keyword
https://read.qxmd.com/read/38535140/development-of-a-micro-ct-scanner-with-dual-energy-option-and-endovascular-contrast-agent-administration-protocol-for-fetal-and-neonatal-virtual-autopsy
#1
JOURNAL ARTICLE
Robert Zboray, Wolf Schweitzer, Lars Ebert, Martin Wolf, Sabino Guglielmini, Stefan Haemmerle, Stephan Weiss, Bruno Koller
The rate of parental consent for fetal and perinatal autopsy is decreasing, whereas parents are more likely to agree to virtual autopsy by non-invasive imaging methods. Fetal and perinatal virtual autopsy needs high-resolution and good soft-tissue contrast for investigation of the cause of death and underlying trauma or pathology in fetuses and stillborn infants. This is offered by micro-computed tomography (CT), as opposed to the limited resolution provided by clinical CT scanners, and this is one of the most promising tools for non-invasive perinatal postmortem imaging...
February 29, 2024: Journal of Imaging
https://read.qxmd.com/read/38519951/partial-facial-duplication-diprosopus-a%C3%A2-case-report-and-review-of-the%C3%A2-literature
#2
JOURNAL ARTICLE
Fathia Omer Salah, Yohannes Girma Zewdie, Semienew Ambachew, Amal Saleh Nour, Tewodros Endale
BACKGROUND: Diprosopus, or craniofacial duplication, is a rare entity that occurs in approximately 1 in 180,000 to 15 million live births. The degree of duplication varies from complete facial duplication to small facial structure duplication like the nose and eye. The cause of diprosopus is unknown though there are proposed factors. CASE PRESENTATION: Our African patient was a term 72 hours old female neonate who was referred to our center with impression of lower facial duplication with two oral cavity that are located side to side separated by large soft tissue, she also had flat nasal bridge with widely separated nostrils and widely spaced eyes...
March 23, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38517473/optimal-protein-concentration-in-diets-for-sows-during-the-transition-period
#3
JOURNAL ARTICLE
Jakob C Johannsen, Martin T Sørensen, Peter K Theil, Thomas S Bruun, Chantal Farmer, Takele Feyera
The aim of present study was to determine the optimal concentration of dietary protein required in transition diets for multiparous sows that enhance the farrowing process, colostrum production, and subsequent lactation performance. Forty-eight multiparous sows were allotted to one of six dietary treatments according to bodyweight (290 ± 3 kg) and parity (3.8 ± 0.2) from d 108 of gestation until 24 h after the onset of farrowing. The diets were isoenergetic and contained increasing concentrations of dietary protein (expressed as standardized ileal digestible [SID] Lys) and were supplied at a daily feed supply of 3...
March 22, 2024: Journal of Animal Science
https://read.qxmd.com/read/38511267/preimplantation-genetic-testing-as-a-means-of-preventing-hereditary-congenital-myasthenic-syndrome-caused-by-rapsn
#4
JOURNAL ARTICLE
Zhiping Zhang, Xueluo Zhang, Huiqin Xue, Liming Chu, Lina Hu, Xingyu Bi, Pengfei Zhu, Dongdong Zhang, Jiayao Chen, Xiangrong Cui, Lingyin Kong, Bo Liang, Xueqing Wu
BACKGROUND: Congenital myasthenic syndrome is a heterogeneous group of inherited neuromuscular transmission disorders. Variants in RAPSN are a common cause of CMS, accounting for approximately 14%-27% of all CMS cases. Whether preimplantation genetic testing for monogenic disease (PGT-M) could be used to prevent the potential birth of CMS-affected children is unclear. METHODS: Application of WES (whole-exome sequencing) for carrier testing and guidance for the PGT-M in the absence of a genetically characterized index patient as well as assisted reproductive technology were employed to prevent the occurrence of birth defects in subsequent pregnancy...
March 2024: Molecular Genetics & Genomic Medicine
https://read.qxmd.com/read/38510065/timing-of-dietary-zinc-additions-during-gestation-for-improved-piglet-survival
#5
JOURNAL ARTICLE
Kelsey L Hammers, Pedro E Urriola, Mark Schwartz, Moon-Suhn Ryu, Andres Gomez, Lee J Johnston
The objectives of this study were to determine a practical approach to feeding elevated dietary zinc (Zn) to gestating sows in a commercial setting and to confirm preweaning mortality could be reduced by feeding high Zn to sows during different periods of gestation. The study was conducted at a commercial sow farm in the upper Midwest. Mixed parity sows ( n  = 267) over three consecutive weekly farrowing groups (sows farrowing within 1 wk) were assigned randomly to one of the three dietary treatments within parity...
2024: Translational Animal Science
https://read.qxmd.com/read/38449857/case-report-complex-evaluation-of-coagulation-fibrinolysis-and-inflammatory-cytokines-in-a-sars-cov-2-infected-pregnant-woman-with-fetal-loss
#6
Eszter Lilla Tóth, Rita Orbán-Kálmándi, Zsuzsa Bagoly, Linda Lóczi, Tamás Deli, Olga Török, Sarolta Molnár, Sándor Baráth, Parvind Singh, Zsuzsanna Hevessy, Éva Katona, Miklós Fagyas, Attila Ádám Szabó, Szabolcs Molnár, Zoárd Tibor Krasznai
BACKGROUND: SARS-CoV-2 infection during pregnancy increases the risk of severe obstetrical complications. Detailed evaluation of COVID-19-associated coagulopathy in a pregnancy with stillbirth hasn't been described so far. Besides knowledge gaps in the pathomechanism leading to stillbirth in COVID-19 pregnancies, currently, no prognostic biomarker is available to identify pregnant patients who are at imminent risk of COVID-19-associated maternal and fetal complications, requiring immediate medical attention...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38441368/limb-body-wall-complex-literature-review-and-case-report
#7
Omar Daniel Cortés-Enríquez, Claudia Vanessa Tapia-Fonseca, María Angelina Torres-Fuentes, Paola Berenice Torres-Riojas, Laura Patricia Raya-Garza
INTRODUCTION: Body wall anomalies comprise a wide range of malformations. Limb-Body wall complex (LBWC) represents the most severe presentation of this group, with life threatening malformations in practically all the cases, including craniofacial, body wall defects, and limb anomalies. There is no consensus about its etiology and folding and gastrulation defects have been involved. Also, impaired angiogenesis has been proposed as a causative process. CASE REPORT: We present the case of a masculine stillborn, product of the first pregnancy in a 15-year-old, apparently healthy mother...
March 2024: Birth Defects Research
https://read.qxmd.com/read/38441171/a-role-for-immunohistochemical-stains-in-perinatal-brain-autopsies
#8
JOURNAL ARTICLE
Angela N Viaene
Identification of central nervous system injury is a critical part of perinatal autopsies; however, injury is not always easily identifiable due to autolysis and immaturity of the developing brain. Here, the role of immunohistochemical stains in the identification of perinatal brain injury was investigated. Blinded semiquantitative scoring of injury was performed on sections of frontal lobe from 76 cases (51 liveborn and 25 stillborn) using H&E, GFAP, Iba-1, and β-APP stains. Digital image analysis was used to quantify GFAP and Iba-1 staining...
March 4, 2024: Journal of Neuropathology and Experimental Neurology
https://read.qxmd.com/read/38417962/predictors-of-perinatal-mortality-in-liberia-s-post-civil-unrest-a-comparative-analysis-of-the-2013-and-2019-2020-liberia-demographic-and-health-surveys
#9
JOURNAL ARTICLE
Munawar Harun Koray, Tanya Curry
INTRODUCTION: Perinatal mortality remains a pressing concern, especially in lower and middle-income nations. Globally, 1 in 72 babies are stillborn. Despite advancements, the 2030 targets are challenging, notably in sub-Saharan Africa. Post-war Liberia saw a 14% spike in perinatal mortality between 2013 and 2020, indicating the urgency for in-depth study. OBJECTIVE: The study aims to investigate the predictors of perinatal mortality in Liberia using 2013 and 2019-2020 Liberia Demographic and Health Survey datasets...
February 27, 2024: BMJ Open
https://read.qxmd.com/read/38371599/cloprostenol-sodium-improves-reproductive-performance-of-multiparous-sows-during-lactation
#10
JOURNAL ARTICLE
Xuedan Zhu, Xinke Zhang, Yuqing Zhang, Jiahao Li, Siqi Li, Siqi Zhang, Li Li, Li Meng, Hengxi Wei, Shouquan Zhang
This study aimed to determine the effect of prostaglandin F2α (PGF2α ) analog ( D -cloprostenol sodium and DL -cloprostenol sodium) administration on the milk yield of multiparous sows (MS) and piglet growth performance. In total, 320 Landrace×Yorkshire parturient MS were randomly divided into three groups on day 115 of pregnancy: without treatment ( N  = 50), with 75 μg D -cloprostenol sodium ( N  = 137), and with 200 μg DL -cloprostenol sodium ( N  = 133)...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38360136/pluck-pools-as-diagnostic-samples-for-detecting-porcine-reproductive-and-respiratory-syndrome-virus-and-porcine-circovirus-type-2-in-porcine-abortion-material-and-stillbirths
#11
JOURNAL ARTICLE
Heinrich Kreutzmann, Christine Unterweger, Lukas Schwarz, Katharina Dimmel, Angelika Auer, Till Rümenapf, Andrea Ladinig
Investigating infectious agents in porcine abortion material and stillborn piglets poses challenges for practitioners and diagnostic laboratories. In this study, pooled samples of individual reference organs (thymus and heart) from a total of 1000 aborted fetuses and stillborn piglets were investigated using quantitative PCR protocols for porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) and porcine circovirus type 2 (PCV2). Simultaneously, a pluck-pool containing equivalent portions of fetal thymus, heart, and lung tissue was collected, frozen at - 20°C, and re-analyzed when a certain amount of either PRRSV-1 RNA or PCV2 DNA was detected in individual reference organs...
February 13, 2024: Veterinary Journal
https://read.qxmd.com/read/38338159/effect-of-feeding-a-calcium-chloride-supplement-on-sow-stillbirth-rate
#12
JOURNAL ARTICLE
Sahara Craig, Si-En Ruth Khaw, Kiro R Petrovski, Roy N Kirkwood
The present study was undertaken to determine the effect of daily calcium chloride (CaCl2 ) supplementation from day of entry into the farrowing house until day of farrowing (6.4 ± 0.3 d) on stillbirth rates. Landrace × Large White sows (parities 4 to 6; n = 53) were offered 40 g/d CaCl2 ( n = 28) or served as controls ( n = 25). The morning before their estimated farrowing date, a blood sample was obtained from 25 sows for calcium measurement and a urine sample from 22 sows for pH measurement. The feeding of CaCl2 decreased urinary pH compared to the control group ( p < 0...
February 4, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38325148/genetic-basis-of-sow-hyperprolificacy-and-litter-size-optimization-based-on-a-genome-wide-association-study
#13
JOURNAL ARTICLE
Błażej Nowak, Anna Mucha, Magdalena Zatoń-Dobrowolska, Grzegorz Chrostowski, Wojciech Kruszyński
Over the last few decades, there has been a constant increase in sow litter size, the consequences of which include parturition duration extension, an increase in the percentage of stillborn and hypoxic piglets, and increased variation in piglet birth weight, which reduces their vitality. As such, it seems clear that further increasing sow fertility will generate difficulties and costs in rearing numerous litters with low birth weights. Therefore, the current study aimed to analyze the genetic background of sow hyperprolifcacy using a genome-wide association study (GWAS)...
February 1, 2024: Theriogenology
https://read.qxmd.com/read/38305505/the-prevalence-of-and-factors-associated-with-prior-induced-abortion-among-women-who-gave-birth-in-victoria-2010-2019
#14
JOURNAL ARTICLE
Kristina Edvardsson, Kirsten I Black, Deborah Bateson, Wendy V Norman, Mridula Shankar, Leesa Hooker, Xia Li, Angela J Taft
OBJECTIVE: To assess the prevalence of a history of induced abortion among women who gave birth in Victoria during 2010-2019; to assess the association of socio-demographic factors with a history of induced abortion. STUDY DESIGN: Retrospective cohort study; analysis of cross-sectional perinatal data in the Victorian Perinatal Data Collection (VPDC). SETTING, PARTICIPANTS: All women who gave birth (live or stillborn) in Victoria, 1 January 2010 - 31 December 2019...
February 2, 2024: Medical Journal of Australia
https://read.qxmd.com/read/38285624/effects-of-negative-dietary-anion-cation-difference-and-calcidiol-supplementation-in-transition-diets-fed-to-sows-on-piglet-survival-piglet-weight-and-sow-metabolism
#15
JOURNAL ARTICLE
Alice Caroline Weaver, Thomas Craig Braun, Jeffrey Allan Braun, Helen Marie Golder, Elliot Block, Ian John Lean
Diets that provide a negative dietary anion cation difference (DCAD) and supplement with a vitamin D metabolite 25-OH-D3, (calcidiol) may increase calcium availability at parturition, enhance piglet survival and performance. This factorial study assessed effects of DCAD, calcidiol (50 µg/kg), and parity (parity 1 or >1) and their interactions. Large White and Landrace sows (n = 328), parity 1-8 were randomly allocated in blocks to treatment diets from d 103 of gestation until d 3 post-farrow: (1) negative DCAD without calcidiol (negative DCAD+no CA), n = 84, (2) negative DCAD with calcidiol (negative DCAD+CA) n = 84, (3) positive DCAD without calcidiol (negative DCAD+no CA), n = 81, or (4) positive DCAD with calcidiol (positive DCAD+CA), n = 79...
January 29, 2024: Journal of Animal Science
https://read.qxmd.com/read/38275785/impacts-of-farrowing-pen-design-season-and-sow-parity-on-litter-performance-and-piglet-mortality
#16
JOURNAL ARTICLE
Verônica Madeira Pacheco, Tami M Brown-Brandl, Gary A Rohrer, Rafael Vieira de Sousa, Luciane Silva Martello
Piglet mortality during lactation is a significant concern in swine production, influenced by complex interactions involving sow, piglet, environmental, and management factors. While crushing by the sow may be the ultimate cause of piglet mortality, there are many factors influencing the outcome, including parity, thermal stress, and animal housing systems. New farrowing systems are continuously being developed; however, it is difficult for producers to make decisions without any scientific basis. This study aimed to assess the impact of different farrowing pen layouts on piglet performance, considering parity and season...
January 20, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38252589/gonadal-morphology-of-stillborn-hawksbill-sea-turtle-eretmochelys-imbricata-hatchlings
#17
JOURNAL ARTICLE
Emanuel Lucas Bezerra Rocha, Lucas Gabriel Verissimo Pinheiro da Silva, Isadora Natália Rocha Barreto, Marcela Dos Santos Magalhães, Lucas Castanhola Dias, Radan Elvis Matias de Oliveira, Janine Karla França da Silva Braz, Moacir Franco de Oliveira, Carlos Eduardo Bezerra de Moura
This study aimed to investigate sexual dimorphism in stillborn hawksbill sea turtles (Eretmochelys imbricata) through gonadal morphological characterizations. Macroscopic, light microscopy, and transmission electron analyses were performed for 30 gonad-mesonephros complexes. Female gonads were spindle-shaped and present a translucent whitish appearance with a grainy texture. Male gonads were approximately ovoid with a smooth opaque white surface. A primary sexual difference concerns different marrow structures, with females presenting organized cellularity featuring oocytes, lacunae, and blood vessels, while males presented a distinct organizational medulla pattern marked by testicular cords extending throughout the gonad length...
January 22, 2024: Microscopy and Microanalysis
https://read.qxmd.com/read/38247023/hydrocephalus-associated-with-a-molar-tooth-sign-a-distinct-subtype-of-joubert-syndrome
#18
Michal Gafner, Leila Haddad, Rachna Gupta, Zvi Leibovitz, Itamar Zilberman Ron, Liat Ben-Sira, Stephanie Libzon, Liat Gindes, Eugen Boltshauser, Tally Lerman-Sagie
Hydrocephalus is rarely described in Joubert-Boltshauser syndrome (JBTS). The aim of this study was to investigate whether this association is a chance occurrence or potentially signifies a new phenotypic subtype. The databases of Wolfson Medical Center, Sourasky Medical Center, and EB's personal collection were reviewed. Records from an additional family were obtained from RG. The patients' medical records, prenatal ultrasounds, and magnetic resonance imaging were assessed. In addition, we reviewed the medical literature for the association of ventriculomegaly/hydrocephalus (VM/HC) in JBTS...
January 21, 2024: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/38223290/an-abortion-storm-in-a-goat-farm-in-the-northeast-region-of-brazil-was-caused-by-the-atypical-toxoplasma-gondii-genotype-13
#19
JOURNAL ARTICLE
Vinícius Longo Ribeiro Vilela, Thais Ferreira Feitosa, Sara Vilar Dantas Simões, Rinaldo Aparecido Mota, Frank Katzer, Paul M Bartley
The objective of this study was to characterise a Toxoplasma gondii -induced abortion outbreak on a goat farm in the State of Paraíba, Northeast Region of Brazil. From a herd of 10 does, seven experienced abortions and one gave birth to twins (one stillborn and the other weak and underdeveloped). Serum samples from all of the does were analysed by indirect fluorescent antibody test (IFAT). Samples of colostrum and placenta from two does, along with lung, heart, brain and umbilical cord samples from four of the foetuses, were screened by nested ITS1 PCR specific for T...
2024: Curr Res Parasitol Vector Borne Dis
https://read.qxmd.com/read/38217893/influence-of-prepartum-feed-levels-on-colostrum-production-and-farrowing-performance-in-highly-prolific-sows-in-a-tropical-environment
#20
JOURNAL ARTICLE
Y K Adi, P Taechamaeteekul, J Ruampatana, M Malison, J Suwimonteerabutr, R N Kirkwood, P Tummaruk
Currently, there is a lack of data on the effects of altering feed levels on sow performance and piglet characteristics during the transition period in tropical environments. The present study determined the effect of sow feed levels during the transition period on colostrum yield, colostrum immunoglobulin (Ig) G, colostrum intake of piglets, farrowing duration, proportion of stillborn piglets per litter (SB) and the incidence of farrowing assistance in highly prolific sows. A total of 114 Landrace × Yorkshire crossbred sows and their offspring (n = 2 072) were included in the experiment...
December 21, 2023: Animal
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