Tong Wang, Yan Guo, Xiao-Wei Shi, Yang Gao, Jia-Yi Zhang, Chun-Jiu Wang, Xue Yang, Qi Shu, Xi-Lin Chen, Xin-Yi Fu, Wen-Shan Xie, Yi Zhang, Bin Li, Chang-Qing Guo
Subchondral bone lesions, as the crucial inducement for accelerating cartilage degeneration, have been considered as the initiating factor and the potential therapeutic target of knee osteoarthritis (KOA). Acupotomy, the biomechanical therapy guided by traditional Chinese meridians theory, alleviates cartilage deterioration by correcting abnormal mechanics. Whether this mechanical effect of acupotomy inhibits KOA subchondral bone lesions is indistinct. This study aimed to investigate the effects of acupotomy on inhibiting subchondral bone resorption and to define the possible mechanism in immobilization-induced KOA rabbits...
2021: Evidence-based Complementary and Alternative Medicine: ECAM