keyword
https://read.qxmd.com/read/38534204/clinical-significance-of-posterior-expansion-of-the-utricular-endolymphatic-space
#1
JOURNAL ARTICLE
Hideyuki Kaida, Tadao Yoshida, Satofumi Sugimoto, Masumi Kobayashi, Shinji Naganawa, Michihiko Sone
BACKGROUND: Posterior expansion of the utricular endolymphatic space (ES) is a finding occasionally observed, and often occurs in bilateral ears. The clinical significance of posterior expansion of the utricular ES is not clear. OBJECTIVES: To investigate the clinical significance of posterior expansion of the utricular ES detected on magnetic resonance imaging (MRI). MATERIALS AND METHODS: Among 957 patients who underwent contrast-enhanced MRI to investigate the presence of endolymphatic hydrops (EH), clinical findings in cases with posterior expansion of the utricular ES were evaluated and the significance of their existence is considered...
March 27, 2024: Acta Oto-laryngologica
https://read.qxmd.com/read/38529449/exploring-the-significance-of-vitamin-d-levels-as-a-biomarker-in-ear-diseases-a-narrative-review
#2
REVIEW
Muhammad Hamayal, Saleh Khurshied, Muhammad A Zahid, Nawal Khurshid, Warda Shahid, Maesum Ali, Hammad Ahmed, Mehrun Nisa
This narrative review examines the role of vitamin D as a biomarker in ear disorders, including benign paroxysmal positional vertigo (BPPV), otitis media, bell's palsy, Meniere's disease, and hearing loss. PubMed, The Cochrane Library, and Google Scholar were utilized to conduct a comprehensive literature search, and findings were combined from studies from 2014 to 2024. As highlighted in this review, there is a consistent association between vitamin D deficiency and an increased risk and recurrence of disease especially in BPPV and otitis media...
February 2024: Curēus
https://read.qxmd.com/read/38525688/large-vestibular-aqueduct-associated-symptoms-endolymphatic-duct-blockage-as-a-surgical-treatment
#3
JOURNAL ARTICLE
Issam Saliba, Sarah Alshehri, Isabelle Fournier, Nasser Altamami
OBJECTIVE: This study aimed to evaluate the effectiveness of endolymphatic duct blockage (EDB) on dizziness control in patients with a large vestibular aqueduct (LVA) and to evaluate its effect on hearing. STUDY DESIGN: This is a prospective nonrandomized study. SETTING: Five adults and one child with dizziness and five children with progressive hearing loss were referred to our tertiary centers. METHODS: The dizziness handicap inventory (DHI) and DHI-PC (dizziness handicap inventory-patient caregiver) questionnaires were used before and after surgery...
March 18, 2024: Audiology Research
https://read.qxmd.com/read/38522357/otologic-disease-trends-in-japan-post-covid-19-outbreak-a-retrospective-time-series-analysis
#4
JOURNAL ARTICLE
Keisuke Kondo, Keiji Honda, Keiichi Goshima, Norihiko Inoue, Daisuke Shinjo, Takeshi Tsutsumi, Kiyohide Fushimi
OBJECTIVE: To evaluate the potential impact of coronavirus disease 2019 (COVID-19) and vaccinations on otologic diseases, including facial nerve paralysis (including Ramsay Hunt syndrome), vestibular neuritis, sudden sensorineural hearing loss, and Meniere's disease. METHODS: In this retrospective study, we conducted a time-series analysis employing a causal impact algorithm on a large-scale inpatient database in Japan. We compared the actual number of hospitalized patients with otologic diseases to two predictions: one without any covariates and another with a covariate accounting for the reduction in the number of hospitalized patients due to lockdown measures...
March 23, 2024: Auris, Nasus, Larynx
https://read.qxmd.com/read/38520520/machine-learning-models-help-differentiate-between-causes-of-recurrent-spontaneous-vertigo
#5
JOURNAL ARTICLE
Chao Wang, Allison S Young, Chahat Raj, Andrew P Bradshaw, Benjamin Nham, Sally M Rosengren, Zeljka Calic, David Burke, G Michael Halmagyi, Gnana K Bharathy, Mukesh Prasad, Miriam S Welgampola
BACKGROUND: Vestibular migraine (VM) and Menière's disease (MD) are two common causes of recurrent spontaneous vertigo. Using history, video-nystagmography and audiovestibular tests, we developed machine learning models to separate these two disorders. METHODS: We recruited patients with VM or MD from a neurology outpatient facility. One hundred features from six "feature subsets": history, acute video-nystagmography and four laboratory tests (video head impulse test, vestibular-evoked myogenic potentials, caloric testing and audiogram) were used...
March 23, 2024: Journal of Neurology
https://read.qxmd.com/read/38519595/an-overload-of-missense-variants-in-the-otog-gene-may-drive-a-higher-prevalence-of-familial-meniere-disease-in-the-european-population
#6
JOURNAL ARTICLE
Alberto M Parra-Perez, Alvaro Gallego-Martinez, Jose A Lopez-Escamez
Meniere disease is a complex inner ear disorder with significant familial aggregation. A differential prevalence of familial MD (FMD) has been reported, being 9-10% in Europeans compared to 6% in East Asians. A broad genetic heterogeneity in FMD has been described, OTOG being the most common mutated gene, with a compound heterozygous recessive inheritance. We hypothesize that an OTOG-related founder effect may explain the higher prevalence of FMD in the European population. Therefore, the present study aimed to compare the allele frequency (AF) and distribution of OTOG rare variants across different populations...
March 22, 2024: Human Genetics
https://read.qxmd.com/read/38516125/cerebral-small-vessel-disease-in-elderly-patients-with-meni%C3%A3-re-s-disease
#7
JOURNAL ARTICLE
Fieke K Oussoren, Roeland B van Leeuwen, Tjard R Schermer, Louise N F Poulsen, Joost J Kardux, Tjasse D Bruintjes
BACKGROUND: Menière's disease (MD) is an inner ear disease characterized by vertigo attacks, progressive hearing loss, tinnitus, and the sensation of aural fullness. Although the exact pathophysiology of MD is unknown, endolymphatic hydrops is considered to be its histopathological hallmark. It has been suggested that endolymphatic hydrops results from lowered perfusion pressure due to cardiovascular comorbidity. Cardiovascular risk factors can cause cerebral small vessel disease (CSVD), visible on MRI...
June 2023: Otol Neurotol Open
https://read.qxmd.com/read/38515642/spinning-through-history-evolution-of-the-concept-of-vestibular-migraine
#8
JOURNAL ARTICLE
Yoon-Hee Cha
Vestibular migraine represents a growing public health problem, imposing enormous societal burdens in the form of patient suffering, loss of productivity, and direct healthcare costs. This raises the question of how we developed our ideas about vestibular migraine and how these ideas shape how we treat it. This review walks through the history of how our conceptualization of migraine and vestibular symptoms evolved, starting with clinical observations in ancient times, inclusion under the umbrella of Meniere's disease, and then separation from Meniere's disease with its own identity...
September 2023: Otol Neurotol Open
https://read.qxmd.com/read/38510380/habituation-disorders-in-auditory-middle-latency-response-of-persistent-postural-perceptual-dizziness-patients
#9
JOURNAL ARTICLE
Toshihisa Murofushi, Fumiyuki Goto, Munetaka Ushio
OBJECTIVES: To study habituation disorders in auditory middle latency response (AMLR) to repetitive stimuli of persistent postural-perceptual dizziness (PPPD) patients. SUBJECTS: Twenty-eight PPPD (10 men and 18 women, mean 59.5 years of age, 26-81 years of age) were enrolled. For comparison, data of 13 definite vestibular migraine (VM) patients (3 men, 10 women, mean age 45.5), 13 definite unilateral Meniere's disease (MD) patients (2 men, 11 women, mean age 50...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38498740/deep-learning-model-to-evaluate-sensorimotor-system-ability-in-patients-with-dizziness-for-postural-control
#10
JOURNAL ARTICLE
Ahnryul Choi, Euyhyun Park, Tae Hyong Kim, Seungheon Chae, Gi Jung Im, Joung Hwan Mun
Balanced posture without dizziness is achieved via harmonious coordination of visual, vestibular, and somatosensory systems. Specific frequency bands of center of pressure (COP) signals during quiet standing are closely related to the sensory inputs of the sensorimotor system. In this study, we proposed a deep learning-based novel protocol using the COP signal frequencies to estimate the equilibrium score (ES), a sensory system contribution. Sensory organization test was performed with normal controls (n=125), patients with Meniere's disease (n=72) and vestibular neuritis (n=105)...
March 18, 2024: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://read.qxmd.com/read/38489201/sense-of-direction-in-vestibular-disorders
#11
JOURNAL ARTICLE
Alexander I G Moore, John F Golding, Anastasia Alenova, Patricia Castro, Adolfo M Bronstein
BACKGROUND: Our sense of direction (SOD) ability relies on the sensory integration of both visual information and self-motion cues from the proprioceptive and vestibular systems. Here, we assess how dysfunction of the vestibular system impacts perceived SOD in varying vestibular disorders, and secondly, we explore the effects of dizziness, migraine and psychological symptoms on SOD ability in patient and control groups. METHODS: 87 patients with vestibular disorder and 69 control subjects were assessed with validated symptom and SOD questionnaires (Santa Barbara Sense of Direction scale and the Object Perspective test)...
March 10, 2024: Journal of Vestibular Research: Equilibrium & Orientation
https://read.qxmd.com/read/38487324/can-head-sway-patterns-differentiate-between-patients-with-meniere-s-disease-vs-peripheral-vestibular-hypofunction
#12
JOURNAL ARTICLE
Jennifer L Kelly, Maura Cosetti, Anat V Lubetzky
BACKGROUND: Meniere's disease (MD) is defined by episodic vertigo, unilateral sensorineural hearing loss and fluctuating aural symptoms. Due to the variable clinical presentation, objective tests of MD may have significant diagnostic utility. Head kinematics derived from a head-mounted display (HMD) have demonstrated to be sensitive to vestibular dysfunction. The purpose of this pilot study was to investigate whether head sway can differentiate between patients with MD, vestibular hypofunction (VH) and healthy controls...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38486804/trends-in-management-of-m%C3%A3-ni%C3%A3-re-disease-a-trinetx-network-database-analysis
#13
JOURNAL ARTICLE
Tyler J Gallagher, Meredith E Adams, Janet S Choi
This study investigated management practices for Meniere's disease (MD) and their temporal trends from 2008 to 2022 within the TriNetX network database. Study cohort included adult patients (≥18 years) with the diagnosis of MD from TriNetX's multi-institutional medical records (n = 77,493). MD diagnosis and management were queried based on the international classification of diseases, tenth revision, current procedural terminology, and RXNorm codes. Temporal trends were analyzed using joinpoint regression...
2024: OTO Open
https://read.qxmd.com/read/38470852/effects-of-age-on-the-frequency-amplitude-ratio-of-cervical-and-ocular-vestibular-evoked-myogenic-potentials
#14
JOURNAL ARTICLE
Raghav H Jha, Erin G Piker, Jesus Gomez
PURPOSE: An increase in the 1000/500 Hz frequency amplitude ratio (FAR) of the cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP, respectively) may serve as a potential biomarker for diagnosing Meniere's disease (MD). However, the aging process can also result in an increased FAR for VEMPs. In older patients, distinguishing whether changes in VEMP FAR are due to MD or aging processes becomes difficult. We aimed to investigate the effects of age on VEMP FARs and establish a FAR-normative range for different age groups...
March 12, 2024: American Journal of Audiology
https://read.qxmd.com/read/38457037/a-novel-radiomics-nomogram-based-on-t2-sampling-perfection-with-application-optimized-contrasts-using-different-flip-angle-evolutions-space-images-for-predicting-cochlear-and-vestibular-endolymphatic-hydrops-in-meniere-s-disease-patients
#15
JOURNAL ARTICLE
Wei Chen, Sihui Yu, Hanyu Xiao, Naier Lin, Xiaolin Wang, Bingrong Li, Yan Sha
OBJECTIVES: To construct and validate a radiomics nomogram based on T2-sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE) images for predicting cochlear and vestibular endolymphatic hydrops (EH) in Meniere's disease patients. METHODS: A total of 156 patients (312 affected ears) with bilateral definite Meniere's disease who underwent delayed enhancement MRI scans were enrolled in this study. All ears of the patients were divided into a training set (n = 218) and an internal validation set (n = 94)...
March 8, 2024: European Radiology
https://read.qxmd.com/read/38455836/therapeutic-response-of-meniere-s-disease-utilizing-sorbus-domestica
#16
JOURNAL ARTICLE
Richard Williams
Introduction Meniere's disease (MD) is a chronic condition characterized by episodic attacks of vertigo, fluctuating hearing loss, and tinnitus. MD can impart a significant socioeconomic impact with associated progressive hearing loss. First-line therapies consist of diuretics and antihistamines, with second-line therapies including intratympanic steroids and pulse therapy. Third-line treatments include endolymphatic sac surgery (ELSS) followed by intratympanic gentamicin injection and/or vestibular neurectomy...
February 2024: Curēus
https://read.qxmd.com/read/38454292/assessing-cognitive-effort-in-m%C3%A3-ni%C3%A3-re-s-disease-pupillometry-as-a-novel-tool-for-postural-control
#17
JOURNAL ARTICLE
Beatrice Francavilla, Gianluca Velletrani, Carlo Chiaramonte, Stefano Di Girolamo, Pier Giorhio Giacomini
BACKGROUND: This study aimed to investigate the utility of pupillometry as a measure of cognitive effort in individuals with Ménière's disease experiencing chronic postural destabilization. By integrating pupillometry with static posturography, we sought to gain deeper insights into the cognitive demands and arousal levels associated with postural control in this specific patient population. METHODS: The study included 36 patients who met the diagnostic criteria for Ménière's disease and a control group comprising 36 healthy volunteers...
January 2024: Journal of International Advanced Otology
https://read.qxmd.com/read/38437837/-off-the-expert-office-assessment-and-differentiation-of%C3%A2-m%C3%A3-ni%C3%A3-re-s-disease-and-vestibular-migraine
#18
JOURNAL ARTICLE
Alexander Blödow, Tilman Brusis, Leif Erik Walther
No abstract text is available yet for this article.
March 2024: Laryngo- Rhino- Otologie
https://read.qxmd.com/read/38437834/-not-available
#19
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Laryngo- Rhino- Otologie
https://read.qxmd.com/read/38437833/-not-available
#20
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Laryngo- Rhino- Otologie
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