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Pediatric Heart Network

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https://www.readbyqxmd.com/read/27887664/translating-sickle-cell-guidelines-into-practice-for-primary-care-providers-with-project-echo
#1
Lisa M Shook, Christina B Farrell, Karen A Kalinyak, Stephen C Nelson, Brandon M Hardesty, Angeli G Rampersad, Kay L Saving, Wanda J Whitten-Shurney, Julie A Panepinto, Russell E Ware, Lori E Crosby
BACKGROUND: Approximately 100,000 persons with sickle cell disease (SCD) live in the United States, including 15,000 in the Midwest. Unfortunately, many patients experience poor health outcomes due to limited access to primary care providers (PCPs) who are prepared to deliver evidence-based SCD care. Sickle Treatment and Outcomes Research in the Midwest (STORM) is a regional network established to improve care and outcomes for individuals with SCD living in Indiana, Illinois, Michigan, Minnesota, Ohio, and Wisconsin...
2016: Medical Education Online
https://www.readbyqxmd.com/read/27884629/urgent-listing-exceptions-and-outcomes-in-pediatric-heart-transplantation-comparison-to-standard-criteria-patients
#2
Ryan R Davies, Michael A McCulloch, Shylah Haldeman, Samuel S Gidding, Christian Pizarro
BACKGROUND: United Network for Organ Sharing (UNOS) policy enables listing exceptions to avoid penalizing patients with waitlist mortality not captured by standard criteria. Outcomes among patients listed by exception have not been analyzed. METHODS: We performed a retrospective analysis of pediatric (≤17 years of age, n = 4,706) listings (2006 to 2015) for primary, isolated heart transplantation within the UNOS data set, assessing Status 1A exception (n = 211, 4...
October 1, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27882424/influence-of-transplant-center-procedural-volume-on-survival-outcomes-of-heart-transplantation-for-children-bridged-with-mechanical-circulatory-support
#3
Alex Hsieh, Dmitry Tumin, Patrick I McConnell, Mark Galantowicz, Joseph D Tobias, Don Hayes
Transplant center expertise improves survival after heart transplant (HTx) but it is unknown whether center expertise ameliorates risk associated with mechanical circulatory support (MCS) bridge to transplantation. This study investigated whether center HTx volume reduced survival disparities among pediatric HTx patients bridged with extracorporeal membrane oxygenation (ECMO), left ventricular assist device (LVAD), or no MCS. Patients ≤18 years of age receiving first-time HTx between 2005 and 2015 were identified in the United Network of Organ Sharing registry...
November 24, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27855999/assessment-of-growth-6-years-after-the-norwood-procedure
#4
Phillip T Burch, Chitra Ravishankar, Jane W Newburger, Linda M Lambert, Victoria L Pemberton, Suzanne Granger, Alejandro A Floh, Jeffrey B Anderson, Garick D Hill, Kevin D Hill, Matthew E Oster, Alan B Lewis, Kurt R Schumacher, Sinai C Zyblewski, Ryan R Davies, Jeffrey P Jacobs, Wyman W Lai, L LuAnn Minich
: At 6 years of age, patients with hypoplastic left heart syndrome had mean age-adjusted z-scores for weight and height below the normative population, and body mass index was similar to the normative population. Males had the greatest increase in z-scores for body mass index. TRIAL REGISTRATION: ClinicalTrials.gov: NCT00115934.
November 14, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27852427/monitoring-the-hospital-management-of-acute-asthma-the-italian-pediatric-network-experience
#5
A G Martelli, R Bianchi, B Boldrighini, M Bosoni, A De Vuono, A Flores D'Arcais, G Gargantini, R Longhi, M T Ortisi, E Racchi, L Parola
BACKGROUND: The Study Group on Accreditation and Quality Improvement of the Italian Society of Pediatrics has developed an observational study about the hospital management of pediatric patients affected by severe asthma, in order to evaluate how the Guidelines for severe asthma in childhood are applied in the daily practice. METHODS: This study included patients between 2 and 17 years, hospitalized or under short intensive observation for acute asthma. The data collection was carried out through the compilation of on-line forms...
November 2016: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27826711/safety-of-enalapril-in-infants-admitted-to-the-neonatal-intensive-care-unit
#6
Lawrence C Ku, Kanecia Zimmerman, Daniel K Benjamin, Reese H Clark, Christoph P Hornik, P Brian Smith
Enalapril is used to treat hypertension and congestive heart failure in infants. However, enalapril is not labeled for neonates, and safety data in infants are sparse. To evaluate the safety of enalapril in young infants, we conducted a retrospective cohort study of infants who were exposed to enalapril in the first 120 days of life and were cared for in 348 neonatal intensive care units from 1997 to 2012. We determined the proportion of exposed infants who developed adverse events, including death, hypotension requiring pressors, hyperkalemia, and elevated serum creatinine...
November 8, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27726857/completeness-and-accuracy-of-local-clinical-registry-data-for-children-undergoing-heart-surgery
#7
Meena Nathan, Marshall L Jacobs, J William Gaynor, Jane W Newburger, Carolyn Dunbar Masterson, Linda M Lambert, Danielle Hollenbeck-Pringle, Felicia L Trachtenberg, Owen White, Brett R Anderson, Margaret C Bell, Phillip T Burch, Eric M Graham, Jonathan R Kaltman, Kirk R Kanter, Carlos M Mery, Christian Pizarro, Marcus S Schamberger, Michael D Taylor, Jeffrey P Jacobs, Sara K Pasquali
BACKGROUND: Data routinely captured in clinical registries may be leveraged to enhance efficiency of prospective research. The quality of registry data for this purpose has not been studied, however. We evaluated the completeness and accuracy of perioperative data within congenital heart centers' local surgical registries. METHODS: Within 12 Pediatric Heart Network (PHN) sites, we evaluated 31 perioperative variables (and their subcategories, totaling 113 unique fields) collected via sites' local clinical registries for submission to The Society of Thoracic Surgeons Database, compared with chart review by PHN research coordinators...
October 7, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27624592/assessment-of-diastolic-function-in-single-ventricle-patients-after-the-fontan-procedure
#8
Renee Margossian, Lynn A Sleeper, Gail D Pearson, Piers C Barker, Luc Mertens, Michael D Quartermain, Jason T Su, Girish Shirali, Shan Chen, Steven D Colan
BACKGROUND: Patients with functional single ventricles after the Fontan procedure have abnormal cardiac mechanics. The aims of this study were to determine factors that influence diastolic function and to describe associations of diastolic function with current clinical status. METHODS: Echocardiograms were obtained as part of the Pediatric Heart Network Fontan Cross-Sectional Study. Diastolic function grade (DFG) was assessed as normal (grade 0), impaired relaxation (grade 1), pseudonymization (grade 2), or restrictive (grade 3)...
November 2016: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/27576242/automated-identification-of-innocent-still-s-murmur-in-children
#9
Sukryool Kang, Robin Doroshow, James McConnaughey, Raj Shekhar
: Still's murmur is the most common innocent heart murmur in children. It is also the most commonly misdiagnosed murmur, resulting in a high number of unnecessary referrals to pediatric cardiologist. The purpose of this study was to develop a computer algorithm for automated identification of Still's murmur that may help reduce unnecessary referrals. METHODS: We first developed an accurate segmentation algorithm to locate the first and the second heart sounds. Once these sounds were identified, we extracted signal features specific to Still's murmur...
August 26, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27542078/donor-predictors-of-allograft-utilization-for-pediatric-heart-transplantation
#10
Asma M Khan, Robert S Green, Irene D Lytrivi, Raj Sahulee
BACKGROUND: Pediatric heart transplantations are limited by the supply of donor allografts. We sought to determine the cardiac allograft utilization rate for pediatric donors and identify donor factors that predict graft use for transplantation. METHODS: The United Network for Organ Sharing deceased donor database was queried from 4/30/2006 to 3/31/2014. Donor risk factors that might affect graft use for cardiac transplantation were evaluated. The pediatric cardiac graft utilization rate was calculated, and logistic regression modeling was performed to determine the risk factors relationship with graft use for transplantation...
August 19, 2016: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/27513600/utilizing-a-collaborative-learning-model-to-promote-early-extubation-following-infant-heart-surgery
#11
William T Mahle, Susan C Nicolson, Danielle Hollenbeck-Pringle, Michael G Gaies, Madolin K Witte, Eva K Lee, Michelle Goldsworthy, Paul C Stark, Kristin M Burns, Mark A Scheurer, David S Cooper, Ravi Thiagarajan, V Ben Sivarajan, Steven D Colan, Marcus S Schamberger, Lara S Shekerdemian
OBJECTIVE: To determine whether a collaborative learning strategy-derived clinical practice guideline can reduce the duration of endotracheal intubation following infant heart surgery. DESIGN: Prospective and retrospective data collected from the Pediatric Heart Network in the 12 months pre- and post-clinical practice guideline implementation at the four sites participating in the collaborative (active sites) compared with data from five Pediatric Heart Network centers not participating in collaborative learning (control sites)...
October 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27506544/in-hospital-vital-status-and-heart-transplants-after-intervention-for-congenital-heart-disease-in-the-pediatric-cardiac-care-consortium-completeness-of-ascertainment-using-the-national-death-index-and-united-network-for-organ-sharing-datasets
#12
Logan G Spector, Jeremiah S Menk, Jeffrey M Vinocur, Matthew E Oster, Brian A Harvey, James D St Louis, James Moller, Lazaros K Kochilas
BACKGROUND: The long-term outcomes of patients undergoing interventions for congenital heart disease (CHD) remain largely unknown. We linked the Pediatric Cardiac Care Consortium (PCCC) with the National Death Index (NDI) and the United Network for Organ Sharing Dataset (UNOS) registries to study mortality and transplant occurring up to 32 years postintervention. The objective of the current analysis was to determine the sensitivity of this linkage in identifying patients who are known to have died or undergone heart transplant...
2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27362312/effect-of-induction-therapy-on-graft-survival-in-primary-pediatric-heart-transplantation-a-propensity-score-analysis-of-the-unos-database
#13
Ryan Butts, Melanie Davis, Andrew Savage, Ali Burnette, Minoo Kavarana, Scott Bradley, Andrew Atz, Paul J Nietert
BACKGROUND: The use of induction therapy in pediatric heart transplantation has increased. The aim of this study was to investigate the effects of induction therapy on graft survival. METHODS: The United Network for Organ Sharing database was queried for isolated pediatric heart transplants from January 1, 1994, to December 31, 2013. Propensity scores for induction treatment were calculated by estimating probability of induction using a logistic regression model...
June 29, 2016: Transplantation
https://www.readbyqxmd.com/read/27343914/heart-block-following-stage-1-palliation-of-hypoplastic-left-heart-syndrome
#14
Douglas Y Mah, Henry Cheng, Mark E Alexander, Lynn Sleeper, Jane W Newburger, Pedro J Del Nido, Ravi R Thiagarajan, Satish K Rajagopal
OBJECTIVES: Publicly available data from the Pediatric Heart Network's Single Ventricle Reconstruction Trial was analyzed to determine the prevalence, timing, risk factors for, and impact of second- and third-degree heart block (HB) on outcomes in patients who underwent stage 1 palliation (S1P) for hypoplastic left heart syndrome (HLHS). METHODS: The presence and date of onset of post-S1P HB occurring within the first year of life, potential risk factors for HB, and factors known to predict poor outcomes after S1P were extracted...
July 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#15
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27296835/age-related-survival-disparity-associated-with-lung-transplantation-in-cystic-fibrosis-an-analysis-of-the-registry-of-the-international-society-for-heart-and-lung-transplantation
#16
Don Hayes, Allan R Glanville, David McGiffin, Joseph D Tobias, Dmitry Tumin
BACKGROUND: A survival advantage has been demonstrated for lung transplantation (LTx) in the cystic fibrosis (CF) population, but children may be at higher risk of post-transplant mortality than adults. METHODS: The registry of the International Society for Heart and Lung Transplantation (ISHLT) was queried for lung transplants performed during the period 1998 to 2014 in patients with CF. Period differences were assessed by dividing the sample into LTxs performed between 2006 and 2014 and those performed between 1998 and 2005...
September 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27221537/asthma-control-and-need-for-future-asthma-controller-therapy-among-inner-city-hispanic-asthmatic-children-engaged-in-a-pediatric-asthma-disease-management-program-the-breathmobile-program-mobile-asthma-care-for-kids-network
#17
Lyne Scott, Marilyn Li, Salima Thobani, Breck Nichols, Tricia Morphew, Kenny Yat-Choi Kwong
OBJECTIVE: To determine whether significant numbers of asthmatic children with initially rated intermittent asthma later suffer poor asthma control and require the addition of controller medications. METHODS: Inner-city Hispanic children were followed prospectively in an asthma-specific disease management system (Breathmobile) for a period of 2 years. Clinical asthma symptoms, morbidity treatment, and demographic data were collected at each visit. Treatment was based upon National Heart, Lung, and Blood Institute (NHLBI) Expert Panel Report 3 asthma guidelines...
August 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27167022/maladaptive-aortic-properties-after-the-norwood-procedure-an-angiographic-analysis-of-the-pediatric-heart-network-single-ventricle-reconstruction-trial
#18
Sarah T Plummer, Christoph P Hornik, Hamilton Baker, Gregory A Fleming, Susan Foerster, M Eric Ferguson, Andrew C Glatz, Russel Hirsch, Jeffrey P Jacobs, Kyong-Jin Lee, Alan B Lewis, Jennifer S Li, Mary Martin, Diego Porras, Wolfgang A K Radtke, John F Rhodes, Julie A Vincent, Jeffrey D Zampi, Kevin D Hill
OBJECTIVES: Aortic arch reconstruction in children with single ventricle lesions may predispose to circulatory inefficiency and maladaptive physiology leading to increased myocardial workload. We sought to describe neoaortic anatomy and physiology, risk factors for abnormalities, and impact on right ventricular function in patients with single right ventricle lesions after arch reconstruction. METHODS: Prestage II aortic angiograms from the Pediatric Heart Network Single Ventricle Reconstruction trial were analyzed to define arch geometry (Romanesque [normal], crenel [elongated], or gothic [angular]), indexed neoaortic dimensions, and distensibility...
August 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27039842/nationwide-survey-of-the-transfer-of-adults-with-congenital-heart-disease-from-pediatric-cardiology-departments-to-adult-congenital-heart-disease-centers-in-japan
#19
Ryota Ochiai, Hitoshi Kato, Naomi Akiyama, Fukiko Ichida, Atsushi Yao, Ryo Inuzuka, Koichiro Niwa, Isao Shiraishi, Toshio Nakanishi
BACKGROUND: Current Japanese transfer practices for adult congenital heart disease (ACHD) patients in pediatric departments are elucidated in this study. The focus was on 149 facilities (from the Japanese Society of Pediatric Cardiology and Cardiac Surgery Subspecialty Board and the Japanese Association of Children's Hospitals and Related Institutions). One hundred and thirteen facilities were surveyed and the response rate was 75.8%. METHODS AND RESULTS: Twenty-six facilities (23...
April 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/26995379/rationale-and-methodology-of-a-collaborative-learning-project-in-congenital-cardiac-care
#20
REVIEW
Michael J Wolf, Eva K Lee, Susan C Nicolson, Gail D Pearson, Madolin K Witte, Jeryl Huckaby, Michael Gaies, Lara S Shekerdemian, William T Mahle
BACKGROUND: Collaborative learning is a technique through which individuals or teams learn together by capitalizing on one another's knowledge, skills, resources, experience, and ideas. Clinicians providing congenital cardiac care may benefit from collaborative learning given the complexity of the patient population and team approach to patient care. RATIONALE AND DEVELOPMENT: Industrial system engineers first performed broad-based time-motion and process analyses of congenital cardiac care programs at 5 Pediatric Heart Network core centers...
April 2016: American Heart Journal
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