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Electroconvulsive therapy cognitive impairment

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https://www.readbyqxmd.com/read/29172056/electroconvulsive-therapy-and-age-age-related-clinical-features-and-effectiveness-in-treatment-resistant-major-depressive-episode
#1
Chiara Socci, Pierpaolo Medda, Cristina Toni, Lorenzo Lattanzi, Beniamino Tripodi, Giulia Vannucchi, Giulio Perugi
OBJECTIVE: This study was aimed to compare clinical features, treatments outcomes and tolerability between young (18-45 years), middle age (46-64 years) and old (≥ 65 years) patients treated with bilateral ECT for treatment resistant major depressive episode. METHOD: 402 patients were evaluated 1 day prior to ECT and a week after the treatment termination using the Clinical Global Impression Scale (CGI), the Hamilton Rating Scale for Depression-17 items (HAM-D-17), the Brief Psychiatric Rating Scale (BPRS), the Young Mania Rating Scale (YMRS) and the Mini Mental State Examination (MMSE)...
November 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29149717/usefulness-of-the-montreal-cognitive-assessment-moca-to-monitor-cognitive-impairments-in-depressed-patients-receiving-electroconvulsive-therapy
#2
Rémi Moirand, Filipe Galvao, Maxime Lecompte, Emmanuel Poulet, Frédéric Haesebaert, Jerome Brunelin
There is a lack of consensual tools for evaluating the cognitive side-effects in patients with depression who are treated with electroconvulsive therapy (ECT). The objective of this study was to evaluate the usefulness of the Montreal Cognitive Assessment (MoCA) and of the Mini Mental State Examination (MMSE) to monitor cognitive changes in patients with depression receiving ECT. Cognitive functioning was assessed prospectively in 48 patients with unipolar or bipolar depression before and after an ECT course...
November 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29111076/electroconvulsive-therapy-for-depression-with-comorbid-borderline-personality-disorder-or-post-traumatic-stress-disorder-a-matched-retrospective-cohort-study
#3
Tyler S Kaster, David S Goldbloom, Zafiris J Daskalakis, Benoit H Mulsant, Daniel M Blumberger
BACKGROUND: The impact of comorbid borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD) on clinical and cognitive outcomes of electroconvulsive therapy (ECT) in patients with major depressive episodes (MDE) is unknown. OBJECTIVE: Compare clinical response and adverse cognitive effects for MDE patients with comorbid BPD or PTSD to MDE only. METHODS: In a matched retrospective cohort study of 75 patients treated with ECT at an academic psychiatric hospital with DSM-IV MDE and either comorbid BPD, PTSD or both (MDE + BPD/PTSD), 75 MDE patients without BPD or PTSD (MDE-only) were matched...
October 19, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29064146/short-and-long-term-evaluation-of-cognitive-functions-after-electroconvulsive-therapy-in-a-japanese-population
#4
Shunsuke Takagi, Takashi Takeuchi, Naoki Yamamoto, Munehisa Fujita, Ko Furuta, Hiroyo Ishikawa, Nobutaka Motohashi, Toru Nishikawa
AIM: While electroconvulsive therapy (ECT) is a well-established, safe and effective treatment for mental illnesses, the potential for adverse effects on cognitive functions remains controversial. We aimed to evaluate multiple cognitive functions in different time periods before and after ECT in a Japanese population. METHODS: A battery of five neurocognitive tests was administered to patients who underwent a course of ECT treatment at three time-points: before, immediately after, and 4 weeks after ECT...
October 24, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/28937546/a-randomized-nonblind-naturalistic-comparison-of-efficacy-and-cognitive-outcomes-with-right-unilateral-bifrontal-and-bitemporal-electroconvulsive-therapy-in-schizophrenia
#5
Aniket Bansod, Sushma S Sonavane, Nilesh B Shah, Avinash A De Sousa, Chittaranjan Andrade
BACKGROUND: There is little literature on the relative efficacy and cognitive safety of right unilateral (RUL), bifrontal (BF), and bitemporal (BT) electroconvulsive therapy (ECT) in schizophrenia. METHODS: We present a randomized, nonblind, naturalist comparison of a fixed course of 8 moderately high-dose RUL (n = 24), threshold BF (n = 27), and threshold BT (n = 31) ECT in patients with schizophrenia. Assessments included the Positive and Negative Syndrome Scale (PANSS), the Wechsler Memory Scale-Revised, and an autobiographical memory interview...
September 20, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28852245/resolution-of-cognitive-adverse-effects-of-electroconvulsive-therapy-in-persons-with-schizophrenia-a-prospective-study
#6
Channaveerachari Naveen Kumar, Vivek Haridas Phutane, Jagadisha Thirthalli, Naveen Jayaram, Muralidharan Kesavan, Urvakhsh Meherwan Mehta, Vidhi Tyagi, Bangalore N Gangadhar
BACKGROUND: Cognitive impairments are among the most important adverse effects of electroconvulsive therapy (ECT). Although much is known about them in patients with depression, there is very little information about these in persons with schizophrenia. METHODS: In this study, we examined the persistence of cognitive impairments in a subsample of patients (n = 49) with schizophrenia who had earlier participated in a clinical trial comparing the therapeutic and cognitive efficacy of bifrontal ECT (BFECT; n = 23) and bitemporal ECT (BTECT; n = 29) electrode placements...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28748058/electroconvulsive-therapy-hasn-t-negative-effects-on-short-term-memory-function-as-assessed-using-a-bedside-hand-held-device
#7
Helge H O Müller, Mareen Reike, Simon Grosse-Holz, Mareike Röther, Caroline Lücke, Alexandra Philipsen, Johannes Kornhuber, Teja W Grömer
Electroconvulsive therapy (ECT) is effective in the treatment of treatment-resistant major depression. The fear of cognitive impairment after ECT often deters patients from choosing this treatment option. There is little reliable information regarding the effects of ECT on overall cognitive performance, while short-term memory deficits are well known but not easy to measure within clinical routines. In this pilot study, we examined ECT recipients' pre- and post-treatment performances on a digital ascending number tapping test...
March 22, 2017: Mental Illness
https://www.readbyqxmd.com/read/28617690/short-and-long-term-cognitive-outcomes-in-patients-with-major-depression-treated-with-electroconvulsive-therapy
#8
Megha M Vasavada, Amber M Leaver, Stephanie Njau, Shantanu H Joshi, Linda Ercoli, Gerhard Hellemann, Katherine L Narr, Randall Espinoza
OBJECTIVES: The risk of cognitive impairment is a concern for patients with major depressive disorder receiving electroconvulsive therapy (ECT). Here, we evaluate the acute, short-term and long-term effects of ECT on tests of processing speed, executive function, memory, and attention. METHODS: Forty-four patients with major depressive disorder receiving ECT (61% right unilateral, 39% mixed right unilateral-bitemporal, left unilateral, and/or bitemporal lead placement) underwent a cognitive battery prior to ECT (T1), after 2 sessions (T2), and at the end of the index (T3)...
December 2017: Journal of ECT
https://www.readbyqxmd.com/read/28535241/management-of-depression-in-older-adults-a-review
#9
REVIEW
Rob M Kok, Charles F Reynolds
Importance: Depression in older adults is a common psychiatric disorder affecting their health-related quality of life. Major depression occurs in 2% of adults aged 55 years or older, and its prevalence rises with increasing age. In addition, 10% to 15% of older adults have clinically significant depressive symptoms, even in the absence of major depression. Observations: Depression presents with the same symptoms in older adults as it does in younger populations...
May 23, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28453490/plasma-amyloid-%C3%AE-and-alzheimer-s-disease-related-changes-in-late-life-depression
#10
Chiemi Yamazaki, Toshio Tamaoki, Akihiko Nunomura, Kenichi Tamai, Kazuyuki Yasuda, Nobutaka Motohashi
To elucidate an involvement of amyloid dysmetabolism in the pathophysiology of depression, we investigated associations of plasma amyloid-β (Aβ) levels with Alzheimer's disease-related changes in neuroimaging and cognitive dysfunction in patients with late-life depression. Higher plasma Aβ40, but not Aβ42 nor Aβ40/Aβ42 ratio, was associated with higher degree of parahippocampal atrophy and lower verbal fluency performance. Indeed, high plasma Aβ40 predicted poor cognitive prognosis of depressed patients with mild cognitive impairment...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28422271/a-systematic-review-of-left-unilateral-electroconvulsive-therapy
#11
REVIEW
C H Kellner, K G Farber, X R Chen, A Mehrotra, G D N Zipursky
OBJECTIVE: To systematically review the published clinical trials, case series, and case reports on left unilateral (LUL) electrode placement for clinical electroconvulsive therapy (ECT). METHOD: PubMed, Ovid Medline, and the Cochrane Library were searched for articles concerning LUL ECT. Number of patients, efficacy, and cognitive outcomes were extracted from the papers that met our inclusion criteria. RESULTS: A total of 52 articles were included in this review, consisting of 33 clinical trials, seven case series, and 12 case reports...
August 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28297593/clinical-effectiveness-and-cognitive-impact-of-electroconvulsive-therapy-for-schizophrenia-a-large-retrospective-study
#12
Tyler S Kaster, Zafiris J Daskalakis, Daniel M Blumberger
OBJECTIVE: To determine the clinical effectiveness and cognitive impact of electroconvulsive therapy (ECT) in a large clinical sample of patients with schizophrenia and explore factors associated with treatment response and transient cognitive impairment. METHODS: We examined the clinical records of 144 patients with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder who were treated at an academic mental health hospital from October 2009 to August 2014...
April 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28295591/acetylcholinesterase-inhibitors-for-electroconvulsive-therapy-induced-cognitive-side-effects-a-systematic-review
#13
REVIEW
Marieke J Henstra, Elise P Jansma, Nathalie van der Velde, Eleonora L Swart, Max L Stek, Didi Rhebergen
OBJECTIVE: Electroconvulsive therapy (ECT) is an effective treatment for severe late-life depression; however, ECT-induced cognitive side effects frequently occur. The cholinergic system is thought to play an important role in the pathogenesis. We systematically reviewed the evidence for acetylcholinesterase inhibitors (Ache-I) to prevent or reduce ECT-induced cognitive side effects. METHODS: A systematic search was performed in Pubmed, EMBASE, PsychINFO, and the Cochrane database to identify clinical trials investigating the effect of Ache-I on ECT-induced cognitive side effects...
March 10, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28292650/frontal-and-temporal-cortical-functional-recovery-after-electroconvulsive-therapy-for-depression-a-longitudinal-functional-near-infrared-spectroscopy-study
#14
Jinichi Hirano, Akihiro Takamiya, Bun Yamagata, Syogo Hotta, Yukiko Miyasaka, Shenghong Pu, Akira Iwanami, Hiroyuki Uchida, Masaru Mimura
While the efficacy and tolerability of electroconvulsive therapy (ECT) for depression has been well established, the acute effects of ECT on brain function remain unclear. Particularly, although cognitive dysfunction has been consistently observed after ECT, little is known about the extent and time course of ECT-induced brain functional changes, as observed during cognitive tasks. Considering the acute antidepressant effects of ECT on depression, aberrant brain functional responses during cognitive tasks in patients with depression may improve immediately after this treatment...
August 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28053184/current-status-of-electroconvulsive-therapy-for-mood-disorders-a-clinical-review
#15
Dusan Kolar
Electroconvulsive therapy (ECT) is an effective treatment for mood disorders and a viable treatment option especially when urgency of clinical situation requires a prompt treatment response. After acute series of ECT, the ECT long-term treatment may be considered, although this practice may vary significantly between countries or even within the same country, because there is no universal consensus about its indications, duration and frequency of administration. Continuation or maintenance ECT is common in routine clinical practice and clinicians should be aware of the risks of using ECT long term...
February 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/27992893/the-efficacy-and-safety-of-ect-in-population-before-and-after-60-years-of-age
#16
Anna Antosik-Wójcińska, Łukasz Święcicki
OBJECTIVES: The aim of the study was to evaluate efficacy and safety of electroconvulsive therapy (ECT), in two age groups: before and after 60 years of age. METHODS: The study included 107 patients, 62 women and 45 men hospitalized in the Institute of Psychiatry and Neurology and treated with ECT in 2013 and 2014. 76 people were below 60 years; 31 people - above 60. The authors analyzed the course of 1086 ECTs, 747 sessions for patients before 60 and 339 in patients over 60 years of age...
October 31, 2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27828927/effect-of-low-dose-of-ketamine-on-learning-memory-function-in-patients-undergoing-electroconvulsive-therapy-a-randomized-double-blind-controlled-clinical-study
#17
Qibin Chen, Su Min, Xuechao Hao, Lihua Peng, Huaqing Meng, Qinghua Luo, Jianmei Chen, Xiao Li
OBJECTIVES: Converging evidence suggests that low doses of ketamine have antidepressant effects. The feasibility and safety of administering low doses of ketamine as adjunctive medication during electroconvulsive therapy (ECT) to enhance ECT efficacy and mitigate cognitive impairment has attracted much attention. This study investigated the effects of low doses of ketamine on learning and memory in patients undergoing ECT under propofol anesthesia. METHODS: This randomized, placebo-controlled, double-blind study recruited patients with moderate to severe depressive disorders who failed to respond to antidepressants and were scheduled to receive ECT...
June 2017: Journal of ECT
https://www.readbyqxmd.com/read/27771245/early-and-late-onset-depression-in-late-life-a-prospective-study-on-clinical-and-structural-brain-characteristics-and-response-to-electroconvulsive-therapy
#18
Annemiek Dols, Filip Bouckaert, Pascal Sienaert, Didi Rhebergen, Kristof Vansteelandt, Mara Ten Kate, Francois-Laurent de Winter, Hannie C Comijs, Louise Emsell, Mardien L Oudega, Eric van Exel, Sigfried Schouws, Jasmien Obbels, Mike Wattjes, Frederik Barkhof, Piet Eikelenboom, Mathieu Vandenbulcke, Max L Stek
OBJECTIVE: The clinical profile of late-life depression (LLD) is frequently associated with cognitive impairment, aging-related brain changes, and somatic comorbidity. This two-site naturalistic longitudinal study aimed to explore differences in clinical and brain characteristics and response to electroconvulsive therapy (ECT) in early- (EOD) versus late-onset (LOD) late-life depression (respectively onset <55 and ≥55 years). METHODS: Between January 2011 and December 2013, 110 patients aged 55 years and older with ECT-treated unipolar depression were included in The Mood Disorders in Elderly treated with ECT study...
February 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27721186/the-properties-and-utility-of-the-core-measure-of-melancholia
#19
REVIEW
Gordon Parker, Stacey McCraw
BACKGROUND: The CORE measure was designed to assess a central feature of melancholia - signs of psychomotor disturbance (PMD) - and so provide an alternate non-symptom based measure of melancholia or of its probability. This review evaluates development and application studies undertaken over the last 25 years to consider how well it has met its original objectives. METHODS: All studies published using the CORE measure as either the only or an adjunctive measure of melancholia were obtained and are considered in this review...
January 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27663585/the-change-in-facial-emotion-recognition-ability-in-inpatients-with-treatment-resistant-schizophrenia-after-electroconvulsive-therapy
#20
Mihriban Dalkıran, Akif Tasdemir, Tamer Salihoglu, Murat Emul, Alaattin Duran, Mufit Ugur, Ruhi Yavuz
People with schizophrenia have impairments in emotion recognition along with other social cognitive deficits. In the current study, we aimed to investigate the immediate benefits of ECT on facial emotion recognition ability. Thirty-two treatment resistant patients with schizophrenia who have been indicated for ECT enrolled in the study. Facial emotion stimuli were a set of 56 photographs that depicted seven basic emotions: sadness, anger, happiness, disgust, surprise, fear, and neutral faces. The average age of the participants was 33...
September 2017: Psychiatric Quarterly
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