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To evaluate the predictive value of the sFlt-1/PlGF ratio for the prediction of preeclampsia in women with preexisting diabetes mellitus. This is a monocentric retrospective observational study conducted between January 2018 and December 2020. All singleton pregnancies with preexisting diabetes mellitus, who had a dosage of the sFlt-1/PlGF ratio between 30 and 34 + 6 weeks of gestation were included. The principal outcome was preeclampsia. The secondary outcomes were preterm preeclampsia, gestational hypertension, placental abruption, intrauterine fetal death, IUGR, small for gestational age and a composite outcome named "hypertensive disorder of pregnancy" including gestational hypertension, preeclampsia and HELLP syndrome (hemolysis, elevated liver enzymes and low platelet count)...

We report the case of a patient who has been hospitalized for dyspnea. Investigations revealed airway obstruction, eosinophilia, elevated IgE and elevated exhaled nitric oxide. Patient improved with oral corticosteroids (OCS). However, the patient presented two exacerbations requiring OCS during the next twelve months. Chest CT scan revealed two multiloculated parenchymal lesions. Lab test was positive for Echinococcus and Western-Blot confirmed infection with Echinococcus granulosus. Bronchoalveolar lavage confirmed the presence of 6 % eosinophils...

BACKGROUND: Despite systematic thromboprophylaxis, 30% of the COVID-19 patients in intensive care units develop thrombosis. This occurrence is associated with a hypofibrinolytic state measured by thromboelastometry when adding tissue plasminogen activator (tPA) to citrated whole blood for a further run for EXTEM (ROTEM). OBJECTIVES: Because hydroxyethyl starches (HESs) affect fibrin polymerization, we have assessed its potential effect on in vitro tPA-induced fibrinolysis...

PURPOSE: Many artifacts and obstacles associated with cone-beam computed tomography (CBCT) scan can obscure or distort the details of the teeth and occlusal surface, like distorted teeth, streak artifacts, noise, and some malocclusion cases with excessive overlapping between jaws cause decrease the interocclusal space, which can impact diagnosis and treatment planning, and the 3D reconstruction accuracy. Optimizing dental precision by Integrating CBCT scans with other imaging modalities, supply more information to enhance CBCT accuracy, mainly in dental areas with limited clarity...

CONTEXT: Cigarette smoking is a global public health concern, particularly in developing countries. Saudi Arabia has a high prevalence of smoking among young individuals, highlighting the need for interventions to address this issue. AIMS: This study aimed to evaluate the awareness, attitude, smoking rates, and perception of health risks among young individuals in the Jazan region of Saudi Arabia. The goal was to identify areas for improvement and develop effective strategies to combat smoking and promote healthier lifestyles...

Under stress or in optimum conditions, plants foster a specific guild of symbiotic microbes to strengthen pivotal functions including metabolic regulation. Despite that the role of the plant genotype in microbial selection is well documented, the potential of this genotype-specific microbial assembly in maintaining the host homeostasis remains insufficiently investigated. In this study, we aimed to assess the specificity of the foliar metabolic response of contrasting olive genotypes to microbial inoculation with wet-adapted consortia of plant-growth-promoting rhizobacteria (PGPR), to see if previously inoculated plants with indigenous or exogenous microbes would display any change in their leaf metabolome once being subjected to drought stress...

INTRODUCTION: It is well documented that cardiovascular disease (CVD) is the leading cause of death in the US and worldwide, with smoking being the most preventable cause. Additionally, most smokers die from thrombotic-based diseases, in which platelets play a major role. To this end, because of the proven harm of smoking, several novel tobacco products such as electronic(e)-waterpipe have been gaining popularity among different sectors of the population, partly due to their "false" safety claims...

BACKGROUND: In 2016, the Food and Drug Administration approved the first hybrid closed-loop (HCL) insulin delivery system for adults with type 1 diabetes (T1D). There is limited information on the impact of using HCL systems on patient-reported outcomes (PROs) in patients with T1D in real-world clinical practice. In this independent study, we evaluated glycemic parameters and PROs over one year of continuous use of Medtronic's 670G HCL in real-world clinical practice. AIM: To assess the effects of hybrid closed loop system on glycemic control and quality of life in adults with T1D...

This study aimed to evaluate the effectiveness of direct and indirect modified ISO 10272-1:2017 methods for detecting Campylobacter spp. in 10 sites of a poultry slaughterhouse and investigate the relationship between poultry intestinal carriage and carcasses, as well as surfaces contamination during different slaughter steps (scalding, defeathering, evisceration, and rinsing). Antibiotic resistance profiles of the isolates were also determined against 12 antibiotics. A total of 165 intestinal (feces and ceca) and non-intestinal (neck skins and surfaces) samples were collected from 10 different sampling sites before, during, and after the slaughtering of six flocks of broiler chickens...

The aim of this study was to investigate the insecticidal properties of essential oil derived from Eucalyptus cinerea leaves and its main component, 1,8-cineole, against two significant pests of stored dates, Ectomyelois ceratoniae and Ephestia kuehniella (Pyralidae). The impact of the treatment on the sensory characteristics of date fruits was assessed to verify the complete absence of off-odours and off-flavours. Gas chromatography - mass spectrometry analysis of E. cinerea essential oil revealed that the primary compound was 1,8-cineole (74...

According to several international, regional, and national guidelines on hypertension, lifestyle interventions are the first-line treatment to lower blood pressure (BP). Although diet is one of the major lifestyle modifications described in hypertension guidelines, dietary fiber is not specified. Suboptimal intake of foods high in fiber, such as in Westernized diets, is a major contributing factor to mortality and morbidity of noncommunicable diseases due to higher BP and cardiovascular disease. In this review, we address this deficiency by examining and advocating for the incorporation of dietary fiber as a key lifestyle modification to manage elevated BP...

[This corrects the article DOI: 10.1021/acsomega.3c05790.].

The numbers of wastewater treatment plants (WWTP) in Egypt are increasing, yet the general level of pollution associated with wastewater discharge after treatment has not been evaluated. Grey water footprint (GWF) was used to assess the effluent discharges from Zefta WWTP. GWF, before and after treatment, was calculated and followed up to determine its impact on the receiving freshwater body. 150 samples were collected and analysed for BOD5 to determine the optimum operating conditions. Averages values were DO = 2...

IMPORTANCE: The Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP) reported no effect of prostate-specific antigen (PSA) screening on prostate cancer mortality at a median 10-year follow-up (primary outcome), but the long-term effects of PSA screening on prostate cancer mortality remain unclear. OBJECTIVE: To evaluate the effect of a single invitation for PSA screening on prostate cancer-specific mortality at a median 15-year follow-up compared with no invitation for screening...

BACKGROUND: Total thyroidectomy is the main line of treatment for papillary thyroid cancer. Central lymph node dissection (CLND) is still debatable. In this study, we aimed to correlate the central lymph node status with the age of patients. METHODS: This is a retrospective study including patients with papillary thyroid cancer (PTC) who underwent total thyroidectomy and CLND at a tertiary cancer center during the period from January 2012 to September 2022. Patients were subdivided into 3groups: patients younger than 20 years old, patients between 20 and 40 years old, and patients older than 40 years old...

Water, as an indispensable constituent of life, serves as the primary source of sustenance for all living things on Earth. The contamination of surface water with heavy metals poses a significant global health risk to humans, animals, and plants. Sharkiya Governorate, situated in the East Nile Delta region of Egypt, is particularly susceptible to surface water pollution due to various industrial, agricultural, and urban activities. The Bahr Mouse Stream, crucial for providing potable water and supporting irrigation activities in Sharkiya Governorate, caters to a population of approximately 7...

BACKGROUND: Extracellular vesicles (EVs) present in oviductal (OF) and uterine fluid (UF) have been shown to enhance bovine embryo quality during in vitro culture by reducing lipid contents and modulating lipid metabolism-related genes (LMGs), while also influencing cell proliferation, suggesting their involvement on the regulation of different biological pathways. The regulation of signaling pathways related to cell differentiation, proliferation, and metabolism is crucial for early embryo development and can determine the success or failure of the pregnancy...

In order to maximize the utilization of noble metals in catalysis, single atom of palladium (Pd) and platinum (Pt) were incorporated individually in the framework of porous ceria (CeO2 ) by using a one-step flash combustion method. Samples with different Pd and Pt loading (0.5, 1, 2.5, and 5 wt%) were prepared and examined by using different analysis techniques such as XRD, ICP, N2 sorption measurements, SEM, HR-TEM, and XPS. The characterization data confirms the formation of zero-state single-atom Pt and Pd (with possible formation of Pd nanoparticles with a size less than 5 nm) incorporated onto the three-dimensional porous ceria structure...

ETHNOPHARMACOLOGICAL RELEVANCE: Infections caused by parasitic worms or helminth continue to pose a great burden on human and animal health, particularly in underdeveloped tropical and subtropical countries where they are endemic. Current anthelmintic drugs present serious limitations and the emergence of drug resistance has made it increasingly challenging to combat such infections (helminthiases). In Bangladesh, medicinal plants are often used by indigenous communities for the treatment of helminthiases...