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https://www.readbyqxmd.com/read/28630787/evaluation-of-aflibercept-treatment-responses-in-eyes-with-bevacizumab-ranibizumab-resistant-wet-age-related-macular-degeneration
#1
Tuncay Topal, Taner Kar, Yıldıray Yıldırım, Sercan Koray Sağdıç, Cihan Büyükavşar, Abdullah Kaya, Ali Ayata, Murat Sönmez, Melih Hamdi Ünal
OBJECTIVES: To evaluate anatomic and functional results after switching from intravitreal bevacizumab or ranibizumab treatment to aflibercept for wet (neovascular) age-related macular degeneration. MATERIALS AND METHODS: This retrospective study included 22 eyes of 22 patients resistant to treatment with at least 6 injections of bevacizumab or ranibizumab. The first three injections had been applied monthly, the others pro re nata (PRN). Outcome measures were follow-up period, injection number, best corrected visual acuity (BCVA), central retinal thickness (CRT) and pigment epithelial detachment (PED) height...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28628356/clips-versus-resilient-liners-used-with-bilateral-posterior-prefabricated-bars-for-retaining-four-implant-supported-mandibular-overdentures
#2
Mona Gibreel, Mohammed Fouad, Fatma El-Waseef, Nesma El-Amier, Hamdy Marzook
The objective of this research was to clinically compare peri-implant tissue health of bar-clips versus silicone-resilient liners used with bilateral posterior bars for retaining four implant supported mandibular overdentures. Thirty completely edentulous male patients (mean age 65) were randomly assigned into two equal groups. Each patient received four implants in canine and first molar regions of the mandible using flapless surgical technique. Mandibular overdentures were immediately connected to the implants with bilateral prefabricated instant adjusting bars...
June 19, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28626541/a-rare-case-of-three-distinct-epstein-barr-virus-associated-lymphoproliferative-disorders-over-sixteen-years-of-human-immunodeficiency-virus-infection
#3
Hamdy M A Ahmed, Abrar Khan, Weyman Lam, Samar Abohamad, Pradyumna Phatak
Epstein Barr virus (EBV) is well known to cause different types of malignancies. In immunocompromised patients, such as those infected with human immunodeficiency virus (HIV), there is a higher likelihood of EBV related malignant transformation. Diagnosis of EBV related malignancies may be difficult and sometimes requires clinical and pathological correlation. It is very rare to have more than one type of EBV related malignancy in a single patient. Until now, there are no specific guidelines for treatment of EBV related malignancies and lymphoproliferative disorders (LPD)...
June 1, 2017: Hematology Reports
https://www.readbyqxmd.com/read/28623846/sonocad-a-software-to-solve-the-dilemma-of-the-prenatal-diagnosis-of-fetal-syndromes
#4
Mahmoud Abdelnaby, Abdulmeneam Fawzi, Manal Swelem, Hisham Elgammal, Hamdy Elgammal
OBJECTIVE: The aim of this work is to develop an efficient, user friendly, time saving computer software program specified with prenatal diagnosis, based solely on ultrasound findings provided by the sonographer. MATERIALS AND METHOD: SonoCAD (Sonographyic Computer Assisted Diagnosis) program was developed in 4 phases. Phase I, data gathering phase. Phase II the software development phase in which the source code of the software was developed. Phase III, system testing phase, was divided into 2 steps...
June 17, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28621530/tailoring-the-oxygen-reduction-activity-of-hemoglobin-through-immobilization-within-microporous-organic-polymer%C3%A2-graphene-composite
#5
Ahmed B Soliman, Rana R Haikal, Arwa A Abugable, Mohamed H Hassan, Stavros G Karakalos, Perry J Pellechia, Hamdy H Hassan, Magdi Habeeb Yacoub, Mohamed H Alkordi
A facile one pot, bottom up, approach to construct composite materials of Graphene and a pyrimidine-based porous-organic polymer (PyPOP), as host for immobilizing human hemoglobin (Hb) biofunctional molecules is reported. The graphene was selected due to its excellent electrical conductivity, while the PyPOP was utilized due to its pronounced permanent microporosity and chemical functionality. This approach enabled enclathration of the hemoglobin within the microporous composite through a ship-in-a-bottle process, where the composite of the PyPOP@G was constructed from its molecular precursors, under mild reaction conditions...
June 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28621291/role-of-endoscopic-ultrasound-and-endoscopic-ultrasound-guided-fine-needle-aspiration-in-endoscopic-biopsy-negative-gastrointestinal-lesions
#6
Hussein Hassan Okasha, Mohamed Naguib, Mohamed El Nady, Reem Ezzat, Emad Al-Gemeie, Waleed Al-Nabawy, Wael Aref, Ahmed Abdel-Moaty, Karim Essam, Ahmed Hamdy
BACKGROUND AND OBJECTIVES: Many cases of gastrointestinal (GI) tumors as lymphoma, adenocarcinoma, and most of submucosal tumors (SMT) such as gastrointestinal stromal tumor (GIST) and leiomyoma are difficult to diagnose as they frequently yield negative endoscopic biopsies. We evaluated the accuracy of endoscopic ultrasound (EUS) and EUS-guided fine-needle aspiration (EUS-FNA) in the diagnosis of endoscopic biopsy negative GI tumors. PATIENTS AND METHODS: One hundred and nine patients with biopsy negative GI tumors were included in this prospective study...
May 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28621269/tooth-wear-patterns-among-khat-and-shammah-users-in-jazan-city-kingdom-of-saudi-arabia-a-cross-sectional-survey
#7
Mohammed E Sayed, Ammar D Hamdi, Bassam M Hakami, Maryam H Mugri, Shilpa H Bhandi
AIM: The effect of Khat and Shammah habits, with the para-functional jaw activities that accompany them, on the structure and integrity of the natural dentition has not yet been investigated. The literature lacks studies that identify the patterns of tooth wear among Khat and Shammah users. Therefore, this study is the first attempt to address this concern in Jazan City population, Kingdom of Saudi Arabia. MATERIALS AND METHODS: A cross-sectional survey study was conducted among 300 recruits among dental clinics in Jazan City, Kingdom of Saudi Arabia from October 1, 2015, to April 30, 2016...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28620308/the-effect-of-interdialytic-combined-resistance-and-aerobic-exercise-training-on-health-related-outcomes-in-chronic-hemodialysis-patients-the-tunisian-randomized-controlled-study
#8
Bechir Frih, Hamdi Jaafar, Wajdi Mkacher, Zohra Ben Salah, Mohamed Hammami, Ameur Frih
Background: Tunisia has the highest prevalence of hemodialysis patients compared to the other countries in North Africa. Dialysis centers rarely offer an exercise program to prevent physiological and psychological dialysis therapy-related alterations in chronic hemodialysis patients. Aim: To examine the effect of combined endurance-resistance training program on physiological and psychological outcomes in patients undergoing hemodialysis. Methods: We designed a single blinded, randomized, controlled study for a period of 4 months...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28613974/inhibition-of-lateral-prefrontal-cortex-produces-emotionally-biased-first-impressions-a-transcranial-magnetic-stimulation-and-electroencephalography-study
#9
Regina C Lapate, Jason Samaha, Bas Rokers, Hamdi Hamzah, Bradley R Postle, Richard J Davidson
Optimal functioning in everyday life requires the ability to override reflexive emotional responses and prevent affective spillover to situations or people unrelated to the source of emotion. In the current study, we investigated whether the lateral prefrontal cortex (lPFC) causally regulates the influence of emotional information on subsequent judgments. We disrupted left lPFC function using transcranial magnetic stimulation (TMS) and recorded electroencephalography (EEG) before and after. Subjects evaluated the likeability of novel neutral faces after a brief exposure to a happy or fearful face...
June 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28613078/the-impact-of-textile-wastewater-irrigation-on-growth-and-development-of-apple-plant
#10
Hamdi Zenginbal, Gamze Dogdu Okcu, Arda Yalcuk
In this work, the effect of irrigation with textile wastewaters on the growth and development of 'Golden Delicious' apple sapling was examined over a one-year period. Municipal water prepared as a control sample (T0), 1/3 diluted (T1) and undiluted (T2) raw textile wastewater was used as the three different irrigation water samples. Two replications of each test were performed on three random samples each time. When examining the effects of T0, T1 and T2 irrigation water on plant growth, it was found that T1 irrigation water significantly increased the weight, the shoot length and the diameter of the sapling...
June 14, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28608237/exogenous-adipokine-peptide-resistin-protects-against-focal-cerebral-ischemia-reperfusion-injury-in-mice
#11
Jiangtao Zhu, Di Wu, Chenyu Zhao, Man Luo, Ronald C Hamdy, Balvin H L Chua, Xingshun Xu, Zhigang Miao
Previous studies have demonstrated that plasma resistin levels were increased in patients with acute ischemic stroke. However, the role of resistin after ischemic brain injury is still unclear. In this study, we investigated the protective effects of resistin on cerebral ischemia/reperfusion injury in a middle cerebral artery occlusion mouse model. We found that resistin (i.c.v.) significantly reduced infarct volume and improved neurological deficits after 45 min of ischemia and 24 h of reperfusion. Furthermore, our data demonstrate that intraperitoneal administration of resistin (10 µg/kg body weight) also had protective effects on infarct volume, indicating the crossing of resistin through the impaired BBB after ischemia injury...
June 12, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28604181/reference-values-for-maternal-total-and-differential-leukocyte-counts-in-different-trimesters-of-pregnancy-and-the-initial-postpartum-period-in-western-turkey
#12
Muzaffer Sanci, Emrah Töz, Onur Ince, Aykut Özcan, Kevser Polater, Abdurrahman Hamdi Inan, Emrah Beyan, Emrah Akkaya
The aim of this study was to investigate alterations in the leukocyte and differential leukocyte counts in different trimesters of pregnancy and the initial postpartum period. The study population consisted of 40,325 pregnant women. A full blood count and automated differential leukocyte count were performed and all the haemogram results in the different trimesters of pregnancy were recorded. Percentiles were calculated using statistical software. A total of 82,786 complete blood count evaluations were performed in 40,325 subjects from the 6th to 41st week of pregnancy and in the initial postpartum period...
July 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28603834/abstracts-of-the-maghreb-medical-congress-2015
#13
A Dahmeni, M Bouchekoua, D Aloui, S Trabelsi, S Khaled, S Gara, B Herbegue, A Chetoui, S Sellami, I Slama, S Antit, E Boussabah, M Thameur, L Zakhama, S Benyoussef, F Guemira, N Bellil, D Gargouri, N Masmoudi, H Elloumi, N Bibani, D Trad, J Kharrat, I Tounsi, N Fakhfakh, A Kallel, N Hadj Salah, S Belhadj, S Ladab, K Kallell, I Ayadi, S Frikha, M Messaoud, S Belhaj, H Triki, K Kallel, S BenHamida, I Ghribi, A Belkhamsa, M Ben Hamida, I Cheikh, B Hamdi, S Maazaoui, A Berraies, H Sakly, H Blibech, J Ammar, A Hamzaoui, S Belaazri, F Lamine, A Baidada, A Kharbach, A Mensi, A Ben Mohammed, S Khedher, L Mouelhi, F Houissa, T Najjar, R BenJemàa, A Oukaa-Kchaou, I Ben Mefteh, A Ayachi, I Morjène, H Trabelsi, M Mourali, H Maghrebi, M Barka, A Haddad, A Jlassi, A Makni, A Daghfous, W Rebai, F Fteriche, F Chebbi, F Ksantini, A Ammous, M Jouini, M J Kacem, Z Ben Safta, M Cherif, H Zaafouri, A Bouhafa, A Ben Maamer, M Ben Khelifa, O Daboussi, K El Jeri, Y Said, M Salem, R Dabbech, M Hadidane, A Triki, H Henchiri, M Driss, J Ben Hassouna, M Hechiche, T Dhieb, K Rahal, J Lamghari, D Khaiz, Y Ghaddou, P Avala, K El Hattabi, F Z Bensardi, M R Lefriyekh, A Fadil, N O Zerouali, I Benahmed, M Karrou, K Benjaout, R Marouf, I Alloubi, L Achouri, M Slimene, B Laamouri, M Jendoubi, L Satouri, F Ghoul, H Reziga, M Malek, M K Makni, A Baba, A M Derbel, L Sellami, M Zili, R Khelifa, I Benahmed, K Benjaout, I Alloubi, R Maarouf, A Youssef, Bnr Amdouni, M Gharrad, M Saadaoui, M Mbarki, H Rezigua, C Shimi, J Semlani, S Amhajer, H Ghouda, Z Imane, M Gaouzi, Y Kriouile, M Attia, A Ben Amor, S Banneni, K Dimassi, A Triki, M F Gara, B Amdouni, L Bennasser, H Magherbi, I Jallouli, S Harabi, S Kbeili, M Derbel, H Gassara, D Louati, K Chaabene
No abstract text is available yet for this article.
August 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28599704/new-horizons-in-the-extraction-of-bioactive-compounds-using-deep-eutectic-solvents-a-review
#14
REVIEW
Mohamad Hamdi Zainal-Abidin, Maan Hayyan, Adeeb Hayyan, Natesan Subramanian Jayakumar
With the rapid development of ionic liquid analogues, termed 'deep eutectic solvents' (DESs), and their application in a wide range of chemical and biochemical processes in the past decade, the extraction of bioactive compounds has attracted significant interest. Recently, numerous studies have explored the extraction of bioactive compounds using DESs from diverse groups of natural sources, including animal and plant sources. This review summarizes the-state-of-the-art effort dedicated to the application of DESs in the extraction of bioactive compounds...
August 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28590320/sticky-silicone-oil
#15
Hamouda Hamdi Ghoraba, Adel Galal Zaky, Haithem Mamoun Abd Al Fatah, Emad El Din Mohamed El Gemai, Mohamed Amin Heikal
OBJECTIVE: To report and analyze the phenomenon of sticky silicone oil on the retina at the time of its removal. BACKGROUND: Silicone oil has been used for more than 25 years as a long-term retinal tamponade in the surgical management of patients with complex retinal detachments. When a decision to remove silicone oil was made at the end of the tamponade period, the system involved a number of different materials: silicone oil, aqueous solution with or without remnants of perfluorocarbon liquid plus the material of the cannula used to aspirate Silicone oil...
October 31, 2016: Retina
https://www.readbyqxmd.com/read/28584332/immunological-and-genotoxic-effects-of-occupational-exposure-to-%C3%AE-cypermethrin-pesticide
#16
El-Sayed El-Okda, Mona Abdel-Aal Abdel-Hamid, Ahmed Mohamed Hamdy
OBJECTIVES: The aim of this work has been to find out the occupational oxidative stress, immunological and genotoxic health hazards among α-cypermethrin (CYP) pesticide-exposed workers. MATERIAL AND METHODS: A cross-sectional study was performed including 200 workers divided into 3 groups according to the level of exposure: highly exposed group (50 workers), moderately exposed group (50 workers) and unexposed group (100 workers). All workers were subjected to detailed laboratory investigation for gene P53 mutations, immunological parameters as a cluster of differentiation into 3 percentage (CD3%), CD4% and CD8% in addition to peripheral blood total leukocytic and platelet counts that were measured...
June 5, 2017: International Journal of Occupational Medicine and Environmental Health
https://www.readbyqxmd.com/read/28578829/understanding-and-improving-recruitment-to-randomised-controlled-trials-qualitative-research-approaches
#17
REVIEW
Daisy Elliott, Samantha Husbands, Freddie C Hamdy, Lars Holmberg, Jenny L Donovan
CONTEXT: The importance of evidence from randomised trials is now widely recognised, although recruitment is often difficult. Qualitative research has shown promise in identifying the key barriers to recruitment, and interventions have been developed to reduce organisational difficulties and support clinicians undertaking recruitment. OBJECTIVE: This article provides an introduction to qualitative research techniques and explains how this approach can be used to understand-and subsequently improve-recruitment and informed consent within a range of clinical trials...
May 31, 2017: European Urology
https://www.readbyqxmd.com/read/28566936/interaction-of-serum-phosphate-with-age-as-predictors-of-cardiovascular-risk-scores-in-stable-renal-transplant-recipients
#18
Jillian Kerry, Holly Mansell, Hamdi Elmoselhi, Mike Moser, Ahmed Shoker
We calculated rate of changes in the cardiovascular risk calculator for renal transplant recipients (CRCRTR) major adverse cardiac events (MACE) in clinically stable renal transplant recipients (RTRs) to identify covariables that associate with fast cardiovascular (CV) risk progression. CRCRTR-MACE scores were calculated on 139 patients in 2011 and 2014. Score changes above and below median changes in scores were labeled fast or slow CV risk progression. Multivariate analysis (MVA) was performed to identify variables significant to percentage changes in scores...
June 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28562456/the-problem-and-goals-are-global-the-solutions-are-local-revisiting-quality-measurements-and-the-role-of-the-private-sector-in-global-health-professions-education
#19
Hossam Hamdy
The shortage of a competent health workforce is a global challenge. However, its manifestations and proposed solutions are very much context related (i.e., local). In addition to the shortage of health professionals, the quality of health professions education programs, institutions, and graduates, and how to measure quality, are also problematic. Commonly used metrics like the Credit Hours System and the European Credit Transfer and Accumulation System have limitations (e.g., being more focused on quantity than quality)...
May 30, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28562284/epidemiology-of-methicillin-resistant-staphylococcus-aureus-bacteremia-in-children
#20
Rana F Hamdy, Alice J Hsu, Chris Stockmann, Jared A Olson, Matthew Bryan, Adam L Hersh, Pranita D Tamma, Jeffrey S Gerber
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with high rates of treatment failure in adults. The epidemiology, clinical outcomes, and risk factors for treatment failure associated with MRSA bacteremia in children are poorly understood. METHODS: Multicenter, retrospective cohort study of children ≤18 years hospitalized with MRSA bacteremia across 3 tertiary care children's hospitals from 2007 to 2014. Treatment failure was defined as persistent bacteremia >3 days, recurrence of bacteremia within 30 days, or attributable 30-day mortality...
May 5, 2017: Pediatrics
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