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https://www.readbyqxmd.com/read/27902907/thermal-stability-study-of-five-newcastle-disease-attenuated-vaccine-strains
#1
Zineb Boumart, Jihane Hamdi, Samira Daouam, Amal Elarkam, Khalid Omari Tadlaoui, Mehdi El Harrak
Newcastle disease (ND) is a big concern throughout the world because of the devastating losses that can occur with commercial and backyard poultry. The major problem in many countries is the loss of the vaccine's effectiveness due to inadequate use or storage conditions, particularly in hot climates. In the present study, stability of the five, most-used NDV vaccine strains (I-2, LaSota, B1, Clone 30 [C30], and VG-GA) was tested comparatively at different storage temperatures (4 and 37 C for the freeze-dried form and 4, 24, 37, and 45 C for the freeze-dried vaccine reconstituted in diluents)...
December 2016: Avian Diseases
https://www.readbyqxmd.com/read/27900217/can-endourology-fellowship-training-enhance-minimally-invasive-surgery-in-urology-practice
#2
Ahmed M Al-Kandari, Yehya Elshebiny, Hamdy Ibrahim, Ahmad AlShammari, Ahmed A Shokeir
OBJECTIVE: To evaluate the influence of fellowship training in endourology on different endourological procedures in a single institution. SUBJECTS AND METHODS: The operative records of endourological and open surgeries were reviewed. Data analysed included numbers, types, and technical issues related to surgeries. The early study period ranged from September 1998 to September 2004, and the later period from January 2014 to June 2016. The study duration was classified into three periods according to the availability of an endourology fellowship trained member of staff (EFTS)...
December 2016: Arab Journal of Urology
https://www.readbyqxmd.com/read/27886384/valorization-of-functional-properties-of-extract-and-powder-of-olive-leaves-in-raw-and-cooked-minced-beef-meat
#3
Fathia Aouidi, Aicha Okba, Moktar Hamdi
BACKGROUND: Olive leaves (OL), resulting with a huge amount from pruning, were known to be a useful source for biologically active compounds. This paper investigates the potential application of OL as a supplement to minced beef meat, in order to develop a functional product. The effect of OL extract or powder (100, 150 µg phenols g(-1) of meat) on quality and stability of raw and cooked meat, during refrigerated storage, was examined. RESULTS: Microwave drying at 600w gave OL with the highest antioxidant quality (evaluated by TEACphenols and by DPPHphenols , compared to other methods...
November 25, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27883074/adipose-stem-cells-display-higher-regenerative-capacities-and-more-adaptable-electro-kinetic-properties-compared-to-bone-marrow-derived-mesenchymal-stromal-cells
#4
Ahmed El-Badawy, Marwa Amer, Reda Abdelbaset, Sameh N Sherif, Marwan Abo-Elela, Yehya H Ghallab, Hamdy Abdelhamid, Yehea Ismail, Nagwa El-Badri
Adipose stem cells (ASCs) have recently emerged as a more viable source for clinical applications, compared to bone-marrow mesenchymal stromal cells (BM-MSCs) because of their abundance and easy access. In this study we evaluated the regenerative potency of ASCs compared to BM-MSCs. Furthermore, we compared the dielectric and electro-kinetic properties of both types of cells using a novel Dielectrophoresis (DEP) microfluidic platform based on a printed circuit board (PCB) technology. Our data show that ASCs were more effective than BM-MSCs in promoting neovascularization in an animal model of hind-limb ischemia...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27876611/re-emergence-of-amantadine-resistant-variants-among-highly-pathogenic-avian-influenza-h5n1-viruses-in-egypt
#5
Rabeh El-Shesheny, Ola Bagato, Ahmed Kandeil, Ahmed Mostafa, Sara H Mahmoud, Hamdi M Hassanneen, Richard J Webby, Mohamed A Ali, Ghazi Kayali
Highly pathogenic avian influenza (HPAI) H5N1 virus continues to undergo substantial evolution. Emergence of antiviral resistance among H5N1 avian influenza viruses is a major challenge in the control of pandemic influenza. Numerous studies have focused on the genetic and evolutionary dynamics of the hemagglutinin and neuraminidase genes; however, studies on the susceptibility of HPAI H5N1 viruses to amantadine and genetic diversity of the matrix (M) gene are limited. Accordingly, we studied the amantadine susceptibility of the HPAI H5N1 viruses isolated in Egypt during 2006-2015 based on genotypic and phenotypic characteristics...
October 29, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27870364/the-prostate-testing-for-cancer-and-treatment-protect-study-what-have-we-learnt
#6
EDITORIAL
Freddie C Hamdy
No abstract text is available yet for this article.
December 2016: BJU International
https://www.readbyqxmd.com/read/27862740/poor-immune-reconstitution-is-associated-with-symptomatic-bk-polyomavirus-viruria-in-allogeneic-stem-cell-transplant-recipients
#7
Ala Abudayyeh, Amir Hamdi, Maen Abdelrahim, Heather Lin, Valda D Page, Gabriela Rondon, Borje S Andersson, Aimaz Afrough, Charles S Martinez, Jeffrey J Tarrand, Dimitrios P Kontoyiannis, David Marin, A Osama Gaber, Betul Oran, Roy F Chemaly, Sairah Ahmed, Islam Abudayyeh, Amanda Olson, Roy Jones, Uday Popat, Richard E Champlin, Elizabeth J Shpall, Katayoun Rezvani
BACKGROUND: BK polyomavirus (BKPyV) infections are known indicators of immune suppression in hematopoietic stem cell transplant (HSCT) recipients; they can lead to hemorrhagic cystitis, ureteral stenosis, renal dysfunction, and prolonged hospital stays. In this study, we determined transplant-associated variables and immune parameters that can predict for the risk of BKPyV viruria. We hypothesized that BKPyV infection is a marker of poor immune recovery. METHODS: We analyzed all engrafted patients undergoing first allogeneic HSCT at MD Anderson Cancer Center in Houston between January 2004 and December 2012...
November 14, 2016: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/27856154/con-inhaled-pulmonary-vasodilators-are-not-indicated-in-patients-undergoing-lung-transplantation
#8
Mohamed Ehab Ramadan, Muhammad Shabsigh, Hamdy Awad
No abstract text is available yet for this article.
August 31, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27832954/efficient-approach-to-enhance-drug-solubility-by-particle-engineering-of-bovine-serum-albumin
#9
Mouhamad Khoder, Hamdy Abdelkader, Amr ElShaer, Ayman Karam, Mohammad Najlah, Raid G Alany
The aim of this study was to investigate the use of bovine serum albumin (BSA) as a solubility enhancer for indometacin (IND) as a model drug. IND-BSA solid dispersions were prepared by both spray drying and freeze drying techniques using IND:BSA solution (20:1 Molar Ratio (MR)) and IND:BSA suspension (100:1 MR). The solid state of IND in solid dispersions was characterised by SEM, DSC and XRD. The aqueous solubility of IND in the presence of increased amounts of BSA was evaluated. Additionally, IND dissolution and release profiles were evaluated...
November 7, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27832628/associations-of-polymorphisms-in-anti-m%C3%A3-llerian-hormone-amh-ile49ser-and-its-type-ii-receptor-amhrii-482-a-g-on-reproductive-outcomes-and-polycystic-ovary-syndrome-a-systematic-review-and-meta-analysis
#10
Noel Pabalan, Erik Montagna, Eloisa Singian, Lani Tabangay, Hamdi Jarjanazi, Caio Parente Barbosa, Bianca Bianco
BACKGROUND/AIMS: Reported associations of reproductive outcomes (RO) and polycystic ovary syndrome (PCOS) with genotypes of the Ile49Ser and -482A>G polymorphisms in the Anti-Müllerian hormone (AMH) gene and its type II receptor (AMHRII), respectively, have conflicting results. METHODS: PubMed, Google Scholar and Science Direct databases were searched for studies that investigated Ile49Ser and -482A>G in RO and PCOS. Using the metaanalytic approach, we estimated risk (odds ratio [OR] with 95% confidence intervals) using standard genetic models...
2016: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/27830401/investigating-the-prostate-specific-antigen-body-mass-index-and-age-relationship-is-an-age-bmi-adjusted-psa-model-clinically-useful
#11
Sean Harrison, Kate Tilling, Emma L Turner, J Athene Lane, Andrew Simpkin, Michael Davis, Jenny Donovan, Freddie C Hamdy, David E Neal, Richard M Martin
PURPOSE: Previous studies indicate a possible inverse relationship between prostate-specific antigen (PSA) and body mass index (BMI), and a positive relationship between PSA and age. We investigated the associations between age, BMI, PSA, and screen-detected prostate cancer to determine whether an age-BMI-adjusted PSA model would be clinically useful for detecting prostate cancer. METHODS: Cross-sectional analysis nested within the UK ProtecT trial of treatments for localized cancer...
November 9, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27823609/inpatient-diabetes-management-in-the-twenty-first-century
#12
REVIEW
Natasha B Khazai, Osama Hamdy
In hospitalized patients, both hyperglycemia and hypoglycemia have been associated with poor outcomes. During the inpatient period, hyperglycemia has been associated with increased risk of infection, cardiovascular events, and mortality. It is also associated with longer length of hospital stay. Hypoglycemia has also been associated with an increased risk of mortality. Therefore, current evidence supports avoidance of both conditions among hospitalized patients whether they are admitted to critical care units or noncritical care units...
December 2016: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/27823606/nutrition-in-diabetes
#13
REVIEW
Osama Hamdy, Mohd-Yusof Barakatun-Nisak
Medical nutrition therapy (MNT) is a key component of diabetes management. The importance of balancing macronutrients, reducing carbohydrate load, lowering glycemic index, and implementing an overall healthy dietary pattern are emerging as better approaches for MNT in diabetes. Recent research points to improved glycemic control, reduction in body weight, and improvement in many cardiovascular risk factors when these approaches are provided by registered dietitians or health care providers. This review article discusses the current evidence about the role of sensible nutrition in diabetes management...
December 2016: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/27822337/on-the-anticataractogenic-effects-of-l-carnosine-is-it-best-described-as-an-antioxidant-metal-chelating-agent-or-glycation-inhibitor
#14
Hamdy Abdelkader, Michael Longman, Raid G Alany, Barbara Pierscionek
Purpose. L-Carnosine is a naturally occurring dipeptide which recently gained popularity as an anticataractogenic agent due to its purported antioxidant activities. There is a paucity of research and conclusive evidence to support such claims. This work offers compelling data that help clarify the mechanism(s) behind the anticataract properties of L-carnosine. Methods. Direct in vitro antioxidant free radical scavenging properties were assayed using three different antioxidant (TEAC, CUPRAC, and DPPH) assays...
2016: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/27819353/a-novel-non-peptidic-agonist-of-the-ghrelin-receptor-with-orexigenic-activity-in-vivo
#15
Elena Pastor-Cavada, Leticia M Pardo, Dalia Kandil, Cristina Torres-Fuentes, Sarah L Clarke, Hamdy Shaban, Gerard P McGlacken, Harriet Schellekens
Loss of appetite in the medically ill and ageing populations is a major health problem and a significant symptom in cachexia syndromes, which is the loss of muscle and fat mass. Ghrelin is a gut-derived hormone which can stimulate appetite. Herein we describe a novel, simple, non-peptidic, 2-pyridone which acts as a selective agonist for the ghrelin receptor (GHS-R1a). The small 2-pyridone demonstrated clear agonistic activity in both transfected human cells and mouse hypothalamic cells with endogenous GHS-R1a receptor expression...
November 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27815609/efficient-method-for-determination-of-methylene-blue-dye-in-water-samples-based-on-a-combined-dispersive-solid-phase-and-cloud-point-extraction-using-cu-oh-2-nanoflakes-central-composite-design-optimization
#16
Farzin Nekouei, Hanieh Kargarzadeh, Shahram Nekouei, Farzaneh Keshtpour, Abdel Salam Hamdy Makhlouf
A new method was developed for the efficient spectrophotometric determination of methylene blue (MB) dye in solutions. The method is based on a combined dispersive solid phase and cloud point extraction using Cu(OH)2 nanoflakes (as an adsorbent). Cu(OH)2 nanoflakes were synthesized by facile and fast methods and characterized using various techniques. The developed method is based on the adsorption of MB on the Cu(OH)2 nanoflakes and transfer into a surfactant-rich phase using Triton X-114 as a nonionic surfactant...
November 4, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27815512/schizophrenia-impact-of-psychopathology-faith-healers-and-psycho-education-on-adherence-to-medications
#17
Karim Abdel Aziz, Mohammed H Elamin, Nisrin M El-Saadouni, Dina Aly El-Gabry, Mahmoud Barakat, Fatima Alhayyas, Hamdy F Moselhy
BACKGROUND: Many patients suffering from psychosis are nonadherent to their medications. Nonadherence can range from treatment refusal to irregular use or partial change in daily medication doses. AIM: To investigate whether symptom dimensions, post-discharge care plans and being involved with faith healer affect the adherence to treatment in patients with schizophrenia. METHOD: A total of 121 patients with schizophrenia were examined 6 weeks post-discharge from the inpatient unit and assessed for full, partial or nonadherence to medication...
December 2016: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/27811930/defining-the-brain-circuits-involved-in-psychiatric-disorders-imi-newmeds
#18
Francesc Artigas, Esther Schenker, Pau Celada, Michael Spedding, Laia Lladó-Pelfort, Noemi Jurado, Mercedes Núñez, Noemi Santana, Eva Troyano-Rodriguez, Maurizio S Riga, Hanna van den Munkhof, Anna Castañé, Hamdy Shaban, Thérèse M Jay, Anushree Tripathi, Bill P Godsil, Claude Sebban, Jean Mariani, Philippe Faure, Samir Takkilah, Zoe A Hughes, Chester J Siok, Mihaily Hajos, Karsten Wicke, Natalia Gass, Wolfgang Weber-Fahr, Alexander Sartorius, Robert Becker, Michael Didriksen, Jesper F Bastlund, Mark Tricklebank, Céline Risterucci, Andreas Meyer-Lindenberg, Adam J Schwarz
Despite the vast amount of research on schizophrenia and depression in the past two decades, there have been few innovative drugs to treat these disorders. Precompetitive research collaborations between companies and academic groups can help tackle this innovation deficit, as illustrated by the achievements of the IMI-NEWMEDS consortium.
November 4, 2016: Nature Reviews. Drug Discovery
https://www.readbyqxmd.com/read/27810339/novel-immunotherapeutic-approaches-for-treatment-of-infertility
#19
REVIEW
Samaneh Abdolmohammadi-Vahid, Shahla Danaii, Kobra Hamdi, Farhad Jadidi-Niaragh, Majid Ahmadi, Mehdi Yousefi
One of the most important reasons of infertility and human reproductive failure is related to uncontrolled immunological response of maternal immune system to early embryo or fetus, that cause rejection of this semi-allograft. Therefore, a tolerance in the immune system is essential to modulate the reactions against the fetus to avoid rejection. The immune system imbalance during implantation or pregnancy may lead to implantation failure or miscarriage. So, use of immunosuppressive or immunomodulator agents can be helpful to prevent immunological attack...
October 31, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27809934/quality-of-life-and-related-factors-among-chronic-hepatitis-b-infected-patients-a-multi-center-study-turkey
#20
Zehra Karacaer, Banu Cakir, Hakan Erdem, Kenan Ugurlu, Gul Durmus, Nevin Koc Ince, Cinar Ozturk, Rodrigo Hasbun, Ayse Batirel, Esmeray Mutlu Yilmaz, Ilkay Bozkurt, Mustafa Sunbul, Aynur Aynioglu, Aynur Atilla, Ayse Erbay, Ayse Inci, Cigdem Kader, Elif Tukenmez Tigen, Gokhan Karaahmetoglu, Seher Ayten Coskuner, Ebru Dik, Huseyin Tarakci, Selma Tosun, Fatime Korkmaz, Servet Kolgelier, Fatma Yilmaz Karadag, Serpil Erol, Kamuran Turker, Ceyda Necan, Ahmet Melih Sahin, Pinar Ergen, Gulsen Iskender, Pinar Korkmaz, Esma Gulesen Eroglu, Yasemin Durdu, Mehmet Ulug, Suna Secil Deniz, Filiz Koc, Saygın Nayman Alpat, Nefise Oztoprak, Omer Evirgen, Hamdi Sozen, Mustafa Dogan, Selcuk Kaya, Safak Kaya, Mustafa Altindis, Emel Aslan, Recep Tekin, Busra Ergut Sezer, Kevser Ozdemir, Gulden Ersoz, Ahmet Sahin, Ilhami Celik, Emsal Aydin, Aliye Bastug, Rezan Harman, Hacer Deniz Ozkaya, Emine Parlak, Ilknur Yavuz, Suzan Sacar, Senol Comoglu, Ercan Yenilmez, Fatma Sirmatel, Ilker Inanc Balkan, Yesim Alpay, Mustafa Hatipoglu, Affan Denk, Gunes Senol, Mehmet Bitirgen, Mehmet Faruk Geyik, Rahmet Guner, Ayten Kadanali, Ahmet Karakas, Mustafa Namiduru, Hatice Udurgucu, Rukiye Pinar Boluktas, Ergenekon Karagoz, Necati Ormeci
BACKGROUND: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. METHODS: This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers...
November 3, 2016: Health and Quality of Life Outcomes
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