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https://www.readbyqxmd.com/read/28705149/f-treegc-a-questionnaire-based-family-tree-creation-software-for-genetic-counseling-and-genome-cohort-studies
#1
Tomoharu Tokutomi, Akimune Fukushima, Kayono Yamamoto, Yasushi Bansho, Tsuyoshi Hachiya, Atsushi Shimizu
BACKGROUND: The Tohoku Medical Megabank project aims to create a next-generation personalized healthcare system by conducting large-scale genome-cohort studies involving three generations of local residents in the areas affected by the Great East Japan Earthquake. We collected medical and genomic information for developing a biobank to be used for this healthcare system. We designed a questionnaire-based pedigree-creation software program named "f-treeGC," which enables even less experienced medical practitioners to accurately and rapidly collect family health history and create pedigree charts...
July 14, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28689107/feasibility-of-thermophilic-anaerobic-processes-for-treating-waste-activated-sludge-under-low-hrt-and-intermittent-mixing
#2
Wanderli Leite, Bruna Scandolara Magnus, Lorena Bittencourt Guimarães, Marco Gottardo, Paulo Belli Filho
Thermophilic anaerobic digestion (AD) arises as an optimized solution for the waste activated sludge (WAS) management. However, there are few feasibility studies using low solids content typically found in the WAS, and that consider uncommon operational conditions such as intermittent mixing and low hydraulic retention time (HRT). In this investigation, a single-stage pilot reactor was used to treat WAS at low HRT (13, 9, 6 and 5 days) and intermittent mixing (withholding mixing 2 h prior feeding). Thermophilic anaerobic digestion (55 °C) was initiated from a mesophilic digester (35 °C) by the one-step startup strategy...
July 6, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28655114/establishment-of-thermophilic-anaerobic-terephthalic-acid-degradation-system-through-one-step-temperature-increase-startup-strategy-revealed-by-illumina-miseq-sequencing
#3
Kai-Li Ma, Xiang-Kun Li, Ke Wang, Ling-Wei Meng, Gai-Ge Liu, Jie Zhang
Over recent years, thermophilic digestion was constantly focused owing to its various advantage over mesophilic digestion. Notably, the startup approach of thermophilic digester needs to be seriously considered as unsuitable startup ways may result in system inefficiency. In this study, one-step temperature increase startup strategy from 37 °C to 55 °C was applied to establish a thermophilic anaerobic system treating terephthalic acid (TA) contained wastewater, meanwhile, the archaeal and bacterial community compositions at steady periods of 37 °C and 55 °C during the experimental process was also compared using Illumina Miseq Sequencing...
June 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28648746/anaerobic-digestion-of-solid-agroindustrial-waste-in-semi-continuous-mode-evaluation-of-mono-digestion-and-co-digestion-systems
#4
Frantseska-Maria Pellera, Evangelos Gidarakos
The present study aimed at investigating the anaerobic digestion of four agroindustrial waste, namely cotton gin waste, winery waste, olive pomace and juice industry waste, in semi-continuous mode, conducting mono-digestion and co-digestion assays, using an artificial organic fraction sample as co-substrate. These assays were divided into two groups, in which different conditions were applied. Group I investigated the variation in two operational parameters, i.e. the organic loading rate (OLR) and the hydraulic retention time (HRT), while in Group II, the assays were fed with different substrates in a sequential order...
June 22, 2017: Waste Management
https://www.readbyqxmd.com/read/28630743/comparison-of-five-video-assisted-intubation-devices-by-novice-and-expert-laryngoscopists-for-use-in-the-aeromedical-evacuation-environment
#5
Matthew C Wallace, SSgt Tyler Britton, Robbie Meek, Sharon Walsh-Hart, Col Todd E Carter, Steven J Lisco
BACKGROUND: The critically ill or injured patient undergoing military medical evacuation may require emergent intubation. Intubation may be life-saving, but it carries risks. The novice or infrequent laryngoscopist has a distinct disadvantage because experience is critical for the rapid and safe establishment of a secured airway. This challenge is compounded by the austere environment of the back of an aircraft under blackout conditions. This study determined which of five different video-assisted intubation devices (VAIDs) was best suited for in-flight use by U...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28610478/a-new-method-of-auxiliary-purification-for-motor-vehicle-exhaust
#6
Dingqi Li
As a result of the limitations of current purification technologies, purification efficiency is relatively low, particularly during startup or in the case of other abnormal automobile exhaust. Therefore, a new method of auxiliary purification is proposed in this paper. The acidic solution of potassium permanganate can oxidize carbon monoxide, nitrogen oxides and sulfur dioxide at relatively high temperatures and the alkaline solution of potassium permanganate can selectively absorb nitrogen oxide and sulfur dioxide...
June 19, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28599810/comparative-cost-benefit-analysis-of-tele-homecare-for-community-dwelling-elderly-in-japan-non-government-versus-government-supported-funding-models
#7
Miki Akiyama, Chon Abraham
OBJECTIVE: Tele-homecare is gaining prominence as a viable care alternative, as evidenced by the increase in financial support from international governments to fund initiatives in their respective countries. The primary reason for the funding is to support efforts to reduce lags and increase capacity in access to care as well as to promote preventive measures that can avert costly emergent issues from arising. These efforts are especially important to super-aged and aging societies such as in Japan, many European countries, and the United States (US)...
August 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28582555/enablers-of-innovation-in-digital-public-health-surveillance-lessons-from-flutracking
#8
Craig B Dalton
Opportunities for digital innovation in public health surveillance have never been greater. Social media data streams, Open Data initiatives, mHealth geotagged data, and the 'internet of things' are ripe for development. To embrace these opportunities we need to provide public health professionals with environments that support experimentation with new technology. Innovative practitioners will lead discovery, adaption, trialling and deployment of new technological solutions mostly developed outside their organisation...
May 1, 2017: International Health
https://www.readbyqxmd.com/read/28545601/startup-of-a-partial-nitritation-anammox-mbbr-and-the-implementation-of-ph-based-aeration-control
#9
Stephanie Klaus, Rick Baumler, Bob Rutherford, Glenn Thesing, Hong Zhao, Charles Bott
  The single-stage deammonification moving bed biofilm reactor (MBBR) is a process for treating high strength nitrogen waste streams. In this process, partial nitritation and anaerobic ammonia oxidation (anammox) occur simultaneously within a biofilm attached to plastic carriers. An existing tank at the James River Treatment Plant (76 ML/d) in Newport News, Virginia was modified to install a sidestream deammonification MBBR process. This was the second sidestream deammonification process in North America and the first MBBR type installation...
June 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28511759/telehealth-business-boom-times-but-profits-may-wait
#10
Robert Calandra
What we have here is irrational telehealth exuberance. Investors are plowing millions into startups. And even though millennials could be eager adopters, these are still early days for the industry. It may take years-and some regulatory changes-for profits to materialize.
April 2017: Managed Care
https://www.readbyqxmd.com/read/28500892/enrichment-of-extremophilic-exoelectrogens-in-microbial-electrolysis-cells-using-red-sea-brine-pools-as-inocula
#11
Noura A Shehab, Juan F Ortiz-Medina, Krishna P Katuri, Ananda Rao Hari, Gary Amy, Bruce E Logan, Pascal E Saikaly
Applying microbial electrochemical technologies for the treatment of highly saline or thermophilic solutions is challenging due to the lack of proper inocula to enrich for efficient exoelectrogens. Brine pools from three different locations (Valdivia, Atlantis II and Kebrit) in the Red Sea were investigated as potential inocula sources for enriching exoelectrogens in microbial electrolysis cells (MECs) under thermophilic (70°C) and hypersaline (25% salinity) conditions. Of these, only the Valdivia brine pool produced high and consistent current 6...
September 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28486469/digital-farming-attracts-cash-to-agtech-startups
#12
Emily Waltz
No abstract text is available yet for this article.
May 9, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28486199/startup-and-operating-characteristics-of-an-external-air-lift-reflux-partial-nitritation-anammox-integrative-reactor
#13
Xiang Li, Yong Huang, Yi Yuan, Zhen Bi, Xin Liu
The differences in the physiological characteristics between AOB and ANAMMOX bacteria lead to suboptimal performance when used in a single reactor. In this study, aerobic and anaerobic zones with different survival environments were constructed in a single reactor to realize partitioned culture of AOB and ANAMMOX bacteria. An external air-lift reflux system was formed which used the exhaust from the aeration zone as power to return the effluent to the aeration zone. The reflux system effectively alleviated the large pH fluctuations and promoted NO2(-)-N to rapidly use by ANAMMOX bacteria, effectively inhibiting the activity of NOB...
August 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28486195/denitrification-using-excess-activated-sludge-as-carbon-source-performance-and-the-microbial-community-dynamics
#14
Haohao Sun, Qiang Wu, Ping Yu, Liangying Zhang, Lin Ye, Xu-Xiang Zhang, Hongqiang Ren
In this study, the feasibility of using excess activated sludge as carbon source for denitrification to remove low concentrations of nitrate from wastewater was investigated. With an optimized upflow anaerobic reactor, high denitrification performance for both synthetic wastewater and effluent from municipal wastewater treatment plant was achieved. The results showed that the nitrate nitrogen can be reduced down to <1mgL(-1) with a hydraulic retention time of 6h. The total nitrogen removal increased with the amount of sludge added, while, the nitrogen removal per unit of added sludge decreased with the amount of sludge added...
August 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28481681/feasibility-of-a-centralized-clinical-trials-coverage-analysis-a-joint-initiative-of-the-american-society-of-clinical-oncology-and-the-national-cancer-institute
#15
Connie M Szczepanek, Patricia Hurley, Marjorie J Good, Andrea Denicoff, Kelly Willenberg, Casey Dawson, Dax Kurbegov
PURPOSE: Clinical trial billing compliance is a challenge that is faced by overburdened clinical trials sites. The requirements place institutions and research sites at increased potential for financial risk. To reduce their risk, sites develop a coverage analysis (CA) before opening each trial. For multisite trials, this translates into system-wide redundancies, inconsistencies, trial delays, and potential costs to sites and patients. These factors exacerbate low accrual rates to cancer clinical trials...
June 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28476004/pcdd-f-emissions-during-startup-and-shutdown-of-a-hazardous-waste-incinerator
#16
Min Li, Chao Wang, Kefa Cen, Mingjiang Ni, Xiaodong Li
Compared with municipal solid waste incineration, studies on the PCDD/F emissions of hazardous waste incineration (HWI) under transient conditions are rather few. This study investigates the PCDD/F emission level, congener profile and removal efficiency recorded during startup and shutdown by collecting flue gas samples at the bag filter inlet and outlet and at the stack. The PCDD/F concentration measured in the stack gas during startup and shutdown were 0.56-4.16 ng I-TEQ Nm(-3) and 1.09-3.36 ng I-TEQ Nm(-3), respectively, far exceeding the present codes in China...
April 12, 2017: Chemosphere
https://www.readbyqxmd.com/read/28456214/communication-appearance-of-undershoots-in-start-up-shear-experimental-findings-captured-by-tumbling-snake-dynamics
#17
Pavlos S Stephanou, Thomas Schweizer, Martin Kröger
Our experimental data unambiguously show (i) a damping behavior (the appearance of an undershoot following the overshoot) in the transient shear viscosity of a concentrated polymeric solution, and (ii) the absence of a corresponding behavior in the transient normal stress coefficients. Both trends are shown to be quantitatively captured by the bead-link chain kinetic theory for concentrated polymer solutions and entangled polymer melts proposed by Curtiss and Bird, supplemented by a non-constant link tension coefficient that we relate to the nematic order parameter...
April 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28440027/the-crispr-cas9-system-their-delivery-in-vivo-and-ex-vivo-applications-and-clinical-development-by-startups
#18
REVIEW
Minjung Song
The CRISPR/Cas9 gene editing system was originally derived from the prokaryotic adaptive immune system mediated by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated proteins (Cas). The system has been successfully applied to genome editing in eukaryotes and has contributed to remarkable advances in the life sciences, in areas ranging from agriculture to genetic disease therapies. For efficient editing and extending the influence of this system, proper delivery of its components is crucial...
April 25, 2017: Biotechnology Progress
https://www.readbyqxmd.com/read/28433898/performance-and-microbial-population-dynamics-during-stable-operation-and-reactivation-after-extended-idle-conditions-in-an-aerobic-granular-sequencing-batch-reactor
#19
Qiulai He, Wei Zhang, Shilu Zhang, Zhuocheng Zou, Hongyu Wang
The evolution of removal performance and bacterial population dynamics of an aerobic granular sequencing batch reactor were investigated during stable operation and reactivation after prolonged storage. The system was run for a period of 130days including the stable condition phase, storage period and the subsequent reactivation process. Excellent removal performance was obtained during the stable operation period, which was decayed by the extended idle conditions. The removal efficiencies for both carbon and nitrogen decayed while phosphorus removal remained unaffected...
August 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28422085/resonant-rectifier-ics-for-piezoelectric-energy-harvesting-using-low-voltage-drop-diode-equivalents
#20
Amad Ud Din, Seneke Chamith Chandrathna, Jong-Wook Lee
Herein, we present the design technique of a resonant rectifier for piezoelectric (PE) energy harvesting. We propose two diode equivalents to reduce the voltage drop in the rectifier operation, a minuscule-drop-diode equivalent (MDDE) and a low-drop-diode equivalent (LDDE). The diode equivalents are embedded in resonant rectifier integrated circuits (ICs), which use symmetric bias-flip to reduce the power used for charging and discharging the internal capacitance of a PE transducer. The self-startup function is supported by synchronously generating control pulses for the bias-flip from the PE transducer...
April 19, 2017: Sensors
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