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https://www.readbyqxmd.com/read/29046968/development-of-an-elution-device-for-virocap-virus-filters
#1
Christine Susan Fagnant, Matthew Toles, Nicolette Angela Zhou, Jacob Powell, John Adolphsen, Yifei Guan, Byron Ockerman, Jeffry Hiroshi Shirai, David S Boyle, Igor Novosselov, John Scott Meschke
Environmental surveillance of waterborne pathogens is vital for monitoring the spread of diseases, and electropositive filters are frequently used for sampling wastewater and wastewater-impacted surface water. Viruses adsorbed to electropositive filters require elution prior to detection or quantification. Elution is typically facilitated by a peristaltic pump, although this requires a significant startup cost and does not include biosafety or cross-contamination considerations. These factors may pose a barrier for low-resource laboratories that aim to conduct environmental surveillance of viruses...
October 19, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29035674/the-startup-performance-and-microbial-distribution-of-an-anaerobic-baffled-reactor-abr-treating-medium-strength-synthetic-industrial-wastewater
#2
Hao Jiang, Hong Nie, Jiangtao Ding, Walter Stinner, Kaixuan Sun, Hongjun Zhou
In this study, an anaerobic baffled reactor (ABR) with seven chambers was applied to treat medium-strength synthetic industrial wastewater (MSIW). The performance of startup and shock test on treating MSIW was investigated. During the acclimation process, the chemical oxygen demand (COD) of MSIW gradually increased from 0 to 2,000 mg L(-1), and the COD removal finally reached 90%. At shock test, the feeding COD concentration increased by one-fifth and the reactor adapted very well with a COD removal of 82%...
October 16, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28989723/single-particle-cryo-em-using-alignment-by-classification-abc-the-structure-of-lumbricus-terrestris-haemoglobin
#3
Pavel Afanasyev, Charlotte Seer-Linnemayr, Raimond B G Ravelli, Rishi Matadeen, Sacha De Carlo, Bart Alewijnse, Rodrigo V Portugal, Navraj S Pannu, Michael Schatz, Marin van Heel
Single-particle cryogenic electron microscopy (cryo-EM) can now yield near-atomic resolution structures of biological complexes. However, the reference-based alignment algorithms commonly used in cryo-EM suffer from reference bias, limiting their applicability (also known as the 'Einstein from random noise' problem). Low-dose cryo-EM therefore requires robust and objective approaches to reveal the structural information contained in the extremely noisy data, especially when dealing with small structures. A reference-free pipeline is presented for obtaining near-atomic resolution three-dimensional reconstructions from heterogeneous ('four-dimensional') cryo-EM data sets...
September 1, 2017: IUCrJ
https://www.readbyqxmd.com/read/28989009/the-surgery-innovation-and-entrepreneurship-development-program-siedp-an-experiential-learning-program-for-surgery-faculty-to-ideate-and-implement-innovations-in-health-care
#4
Jonathan Servoss, Connie Chang, David Olson, Kevin R Ward, Michael W Mulholland, Mark S Cohen
OBJECTIVE: Surgeons are continually engaged in the incorporation of new technologies in their practice. In the operating room and beyond, they combine technical skill with creative problem solving to improve tools and techniques for patient care, making them natural innovators. However, despite their innovative tendencies, education on entrepreneurship and commercialization is severely lacking. Moreover, with increasing pressure to meet productivity metrics, their availability to learn the complexities of commercialization is limited...
October 5, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28971446/determination-of-soft-tissue-breakpoint-based-on-its-temperature-enhancement-pattern-in-vivo-and-in-vitro-experiments
#5
C Austerlitz, I Gkigkitzis, A L S Barros, J Melo, I Haranas, D Campos
The breakpoint of fresh commercial meats and in vivo mice has been assessed using tissue temperature enhancement pattern. A 1 cm length and 0.1 cm diameter gold rod was implanted in fresh chicken breast, beef, fish, and in vivo Mus musculus white mice and was insonated with ultrasound. The temperature enhancement of gold rods was measured with a needle type thermistor over a temperature range from 35 to 50 °C. From these results the breakpoints were determined by plotting the gold rod temperature versus ultrasound exposure duration using the interception point of two curves fitted by a linear regression equations of thermal response above and below 43 °C...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28936795/the-ugly-truth-about-ourselves-and-our-robot-creations-the-problem-of-bias-and-social-inequity
#6
Ayanna Howard, Jason Borenstein
Recently, there has been an upsurge of attention focused on bias and its impact on specialized artificial intelligence (AI) applications. Allegations of racism and sexism have permeated the conversation as stories surface about search engines delivering job postings for well-paying technical jobs to men and not women, or providing arrest mugshots when keywords such as "black teenagers" are entered. Learning algorithms are evolving; they are often created from parsing through large datasets of online information while having truth labels bestowed on them by crowd-sourced masses...
September 21, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28910583/performance-evaluation-of-startup-for-a-yeast-membrane-bioreactor-mbry-treating-landfill-leachate
#7
Míriam C S Amaral, Rosimeire F Gomes, Yara L Brasil, Sílvia M A Oliveira, Wagner G Moravia
The startup process of a membrane bioreactor inoculated with yeast biomass (Saccharomyces cerevisiae) and used in the treatment of landfill leachate was evaluated. The yeast membrane bioreactor (MBRy) was inoculated with an exogenous inoculum, a granulated active dry commercial bakers' yeast. The MBRy was successfully started up with a progressive increase in the landfill leachate percentage in the MBRy feed and the use of Sabouraud Dextrose Broth. The membrane plays an important role in the startup phase because of its full biomass retention and removal of organic matter...
September 14, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/28871987/low-dose-rate-brachytherapy-for-prostate-cancer-in-low-resource-settings
#8
Michelle I Echevarria, Arash O Naghavi, Yazan A Abuodeh, Kamran A Ahmed, Carlos Chevere, Daniel Fernandez, Kosj Yamoah
PURPOSE: In areas with limited health care, it is important to identify and implement effective treatment methods and to optimize available resources. We investigated the implementation of a low-dose-rate (LDR) brachytherapy program for the treatment of prostate cancer (PCa) in a low-resource setting such as Puerto Rico (PR), where PCa is the main cause of cancer-associated death. METHODS AND MATERIALS: After institutional approval, the medical records of patients with nonmetastatic PCa undergoing LDR brachytherapy from 2008 to 2013 were reviewed from PR...
October 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28867405/attitudes-of-chinese-community-members-and-psychiatrists-towards-forensic-psychiatric-assessments
#9
Zhong Shaoling, Wang Jun, Mellsop Graham, Chen Chen, Zhang Simei, Li Qiguang, Wang Qun, Zhou Jiansong, Wang Xiaoping
The aim of this study was to investigate the attitudes of Chinese community members and psychiatrists towards forensic psychiatric assessments. A questionnaire designed to record attitudes toward the current forensic psychiatric assessment procedures and the disposal of mentally ill offenders was developed and distributed via a mobile App. A total of 134 community members and 132 psychiatrists voluntarily completed the questionnaire. Most of responders agreed that the department of public-security has the right to apply for a forensic psychiatric assessment but should not be held solely by that department...
August 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28866406/rapid-startup-of-thermophilic-anaerobic-digester-to-remove-tetracycline-and-sulfonamides-resistance-genes-from-sewage-sludge
#10
Rui Xu, Zhao-Hui Yang, Qing-Peng Wang, Yang Bai, Jian-Bo Liu, Yue Zheng, Yan-Ru Zhang, Wei-Ping Xiong, Kito Ahmad, Chang-Zheng Fan
Spread of antibiotic resistance genes (ARGs) originating from sewage sludge is highlighted as an eminent health threat. This study established a thermophilic anaerobic digester using one-step startup strategy to quickly remove tetracycline and sulfonamides resistance genes from sewage sludge. At least 20days were saved in the startup period from mesophilic to thermophilic condition. Based on the results of 16S rDNA amplicons sequencing and predicted metagenomic method, the successful startup largely relied on the fast colonization of core thermophilic microbial population (e...
August 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28857610/fast-track-to-accreditation-an-implementation-review-of-college-of-american-pathologists-and-international-organization-for-standardization-15189-accreditation
#11
Laila O AbdelWareth, Fasila Pallinalakam, Faisal Ibrahim, Peter Anderson, Muneezeh Liaqat, Bryson Palmer, Jonathan Harris, Saber Bashir, Adnan Alatoom, Manuel Algora, Ahmad Alduaij, Imran Mirza
CONTEXT: - This review examines challenges and opportunities in preparing laboratories in a startup phase for accreditation by both College of American Pathologists (CAP) and International Organization for Standardization (ISO) 15189 in an international setting as it relates to our experience at Cleveland Clinic Abu Dhabi Laboratory. It also discusses some of the strategies used in executing those projects and the added advantages in perusing both types of accreditations. OBJECTIVES: - To share our experience with CAP and ISO 15189 accreditations in a startup international operation in relation to the challenges encountered and implementation strategy success factors...
August 31, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28831702/microbial-community-composition-and-electricity-generation-in-cattle-manure-slurry-treatment-using-microbial-fuel-cells-effects-of-inoculum-addition
#12
Binghan Xie, Weijia Gong, An Ding, Huarong Yu, Fangshu Qu, Xiaobin Tang, Zhongsen Yan, Guibai Li, Heng Liang
Microbial fuel cell (MFC) is a sustainable technology to treat cattle manure slurry (CMS) for converting chemical energy to bioelectricity. In this work, two types of allochthonous inoculum including activated sludge (AS) and domestic sewage (DS) were added into the MFC systems to enhance anode biofilm formation and electricity generation. Results indicated that MFCs (AS + CMS) obtained the maximum electricity output with voltage approaching 577 ± 7 mV (~ 196 h), followed by MFCs (DS + CMS) (520 ± 21 mV, ~ 236 h) and then MFCs with autochthonous inoculum (429 ± 62 mV, ~ 263...
August 22, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28809823/non-equilibrium-microwave-plasma-for-efficient-high-temperature-chemistry
#13
Dirk van den Bekerom, Niek den Harder, Teofil Minea, Nicola Gatti, Jose Palomares Linares, Waldo Bongers, Richard van de Sanden, Gerard van Rooij
A flowing microwave plasma based methodology for converting electric energy into internal and/or translational modes of stable molecules with the purpose of efficiently driving non-equilibrium chemistry is discussed. The advantage of a flowing plasma reactor is that continuous chemical processes can be driven with the flexibility of startup times in the seconds timescale. The plasma approach is generically suitable for conversion/activation of stable molecules such as CO2, N2 and CH4. Here the reduction of CO2 to CO is used as a model system: the complementary diagnostics illustrate how a baseline thermodynamic equilibrium conversion can be exceeded by the intrinsic non-equilibrium from high vibrational excitation...
August 1, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28799380/a-force-level-theory-of-the-rheology-of-entangled-rod-and-chain-polymer-liquids-i-tube-deformation-microscopic-yielding-and-the-nonlinear-elastic-limit
#14
Kenneth S Schweizer, Daniel M Sussman
We employ a first-principles-based, force-level approach to construct the anharmonic tube confinement field for entangled fluids of rigid needles, and also for chains described at the primitive-path (PP) level in two limiting situations where chain stretch is assumed to either be completely equilibrated or unrelaxed. The influence of shear and extensional deformation and polymer orientation is determined in a nonlinear elastic limit where dissipative relaxation processes are intentionally neglected. For needles and PP-level chains, a self-consistent analysis of transverse polymer harmonic dynamical fluctuations predicts that deformation-induced orientation leads to tube weakening or widening...
December 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28744989/impact-of-rurality-and-substance-use-on-young-people-at-ultra-high-risk-for-psychosis
#15
Helen J Stain, Sean A Halpin, Amanda L Baker, Mike Startup, Vaughan J Carr, Ulrich Schall, Kylie Crittenden, Vanessa Clark, Terry J Lewin, Sandra Bucci
BACKGROUND: Longitudinal research into early intervention for youth at ultra high risk (UHR) for psychosis demonstrates beneficial outcomes including increased treatment compliance and greater participation in education and the workforce. Despite known barriers for rural youth accessing mental health services, research comparing urban and rural UHR youth is lacking. The study included an examination of the impact of substance use on functioning of UHR youth. METHODS: Youth aged 12 to 25 years were recruited from the urban area of Newcastle or the rural area of Orange, New South Wales, Australia, and identified as UHR by the Comprehensive Assessment of At Risk Mental States...
July 26, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28705149/f-treegc-a-questionnaire-based-family-tree-creation-software-for-genetic-counseling-and-genome-cohort-studies
#16
RANDOMIZED CONTROLLED TRIAL
Tomoharu Tokutomi, Akimune Fukushima, Kayono Yamamoto, Yasushi Bansho, Tsuyoshi Hachiya, Atsushi Shimizu
BACKGROUND: The Tohoku Medical Megabank project aims to create a next-generation personalized healthcare system by conducting large-scale genome-cohort studies involving three generations of local residents in the areas affected by the Great East Japan Earthquake. We collected medical and genomic information for developing a biobank to be used for this healthcare system. We designed a questionnaire-based pedigree-creation software program named "f-treeGC," which enables even less experienced medical practitioners to accurately and rapidly collect family health history and create pedigree charts...
July 14, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28689107/feasibility-of-thermophilic-anaerobic-processes-for-treating-waste-activated-sludge-under-low-hrt-and-intermittent-mixing
#17
Wanderli Leite, Bruna Scandolara Magnus, Lorena Bittencourt Guimarães, Marco Gottardo, Paulo Belli Filho
Thermophilic anaerobic digestion (AD) arises as an optimized solution for the waste activated sludge (WAS) management. However, there are few feasibility studies using low solids content typically found in the WAS, and that consider uncommon operational conditions such as intermittent mixing and low hydraulic retention time (HRT). In this investigation, a single-stage pilot reactor was used to treat WAS at low HRT (13, 9, 6 and 5 days) and intermittent mixing (withholding mixing 2 h prior feeding). Thermophilic anaerobic digestion (55 °C) was initiated from a mesophilic digester (35 °C) by the one-step startup strategy...
July 6, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28655114/establishment-of-thermophilic-anaerobic-terephthalic-acid-degradation-system-through-one-step-temperature-increase-startup-strategy-revealed-by-illumina-miseq-sequencing
#18
Kai-Li Ma, Xiang-Kun Li, Ke Wang, Ling-Wei Meng, Gai-Ge Liu, Jie Zhang
Over recent years, thermophilic digestion was constantly focused owing to its various advantage over mesophilic digestion. Notably, the startup approach of thermophilic digester needs to be seriously considered as unsuitable startup ways may result in system inefficiency. In this study, one-step temperature increase startup strategy from 37 °C to 55 °C was applied to establish a thermophilic anaerobic system treating terephthalic acid (TA) contained wastewater, meanwhile, the archaeal and bacterial community compositions at steady periods of 37 °C and 55 °C during the experimental process was also compared using Illumina Miseq Sequencing...
October 2017: Chemosphere
https://www.readbyqxmd.com/read/28648746/anaerobic-digestion-of-solid-agroindustrial-waste-in-semi-continuous-mode-evaluation-of-mono-digestion-and-co-digestion-systems
#19
Frantseska-Maria Pellera, Evangelos Gidarakos
The present study aimed at investigating the anaerobic digestion of four agroindustrial waste, namely cotton gin waste, winery waste, olive pomace and juice industry waste, in semi-continuous mode, conducting mono-digestion and co-digestion assays, using an artificial organic fraction sample as co-substrate. These assays were divided into two groups, in which different conditions were applied. Group I investigated the variation in two operational parameters, i.e. the organic loading rate (OLR) and the hydraulic retention time (HRT), while in Group II, the assays were fed with different substrates in a sequential order...
June 22, 2017: Waste Management
https://www.readbyqxmd.com/read/28630743/comparison-of-five-video-assisted-intubation-devices-by-novice-and-expert-laryngoscopists-for-use-in-the-aeromedical-evacuation-environment
#20
Matthew C Wallace, SSgt Tyler Britton, Robbie Meek, Sharon Walsh-Hart, Col Todd E Carter, Steven J Lisco
BACKGROUND: The critically ill or injured patient undergoing military medical evacuation may require emergent intubation. Intubation may be life-saving, but it carries risks. The novice or infrequent laryngoscopist has a distinct disadvantage because experience is critical for the rapid and safe establishment of a secured airway. This challenge is compounded by the austere environment of the back of an aircraft under blackout conditions. This study determined which of five different video-assisted intubation devices (VAIDs) was best suited for in-flight use by U...
2017: Military Medical Research
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