keyword
https://read.qxmd.com/read/38493487/global-dynamics-of-discrete-mathematical-models-of-tuberculosis
#1
JOURNAL ARTICLE
Saber Elaydi, René Lozi
In this paper, we develop discrete models of Tuberculosis (TB). This includes SEI endogenous and exogenous models without treatment. These models are then extended to a SEIT model with treatment. We develop two types of net reproduction numbers, one is the traditional <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:msub><mml:mrow><mml:mi>R</mml:mi></mml:mrow><mml:mn>0</mml:mn></mml:msub></mml:math> which is based on the disease-free equilibrium, and a new net reproduction number <mml:math xmlns:mml="https://www...
December 2024: Journal of Biological Dynamics
https://read.qxmd.com/read/38493480/service-evaluation-suggests-variation-in-clinical-care-provision-in-adults-with-congenital-adrenal-hyperplasia-in-the-uk-and-ireland
#2
JOURNAL ARTICLE
Lauren Madden Doyle, S Faisal Ahmed, Jessica Davis, Sue Elford, Yasir S Elhassan, Lynette James, Neil Lawrence, Sofia Llahana, Grace Okoro, D Aled Rees, Jeremy W Tomlinson, Michael W O'Reilly, Nils P Krone
BACKGROUND: Congenital adrenal hyperplasia (CAH) encompasses a rare group of autosomal recessive disorders, characterised by enzymatic defects in steroidogenesis. Heterogeneity in management practices has been observed internationally. The International Congenital Adrenal Hyperplasia registry (I-CAH, https://sdmregistries.org/) was established to enable insights into CAH management and outcomes, yet its global adoption by endocrine centres remains unclear. DESIGN: We sought (1) to assess current practices amongst clinicians managing patients with CAH in the United Kingdom and Ireland, with a focus on choice of glucocorticoid, monitoring practices and screening for associated co-morbidities, and (2) to assess use of the I-CAH registry...
March 17, 2024: Clinical Endocrinology
https://read.qxmd.com/read/38493430/how-social-is-social-media-for-transgender-and-gender-diverse-youth-association-of-online-social-experiences-with-internalizing-mental-health-problems
#3
JOURNAL ARTICLE
Lena Herrmann, Claus Barkmann, Carola Bindt, Sarah Hohmann, Saskia Fahrenkrug, Inga Becker-Hebly
Adolescents spend a critical amount of their free time on the Internet and social media. Transgender and gender-diverse (TGD) adolescents, who report elevated rates of mental health issues, especially internalizing problems, have both positive and negative online social experiences (e.g., support and cyberbullying). This can have both beneficial and/or harmful effects on their mental health. Given the lack of research, the present study examined TGD adolescents' online (social) experiences and the association of positive and negative online social experiences with internalizing problems...
March 17, 2024: European Child & Adolescent Psychiatry
https://read.qxmd.com/read/38493411/modelling-the-public-health-burden-of-herpes-zoster-and-the-impact-of-adjuvanted-recombinant-zoster-vaccine-in-five-selected-countries-in-southeast-asia
#4
JOURNAL ARTICLE
Ru Han, Peter San Martin, Nurilign Ahmed, Adriana Guzman-Holst, Ahmed Mohy, Thatiana Pinto, Bruna de Veras, Jorge A Gomez, Gyneth Lourdes Bibera, Désirée A M van Oorschot
INTRODUCTION: Herpes zoster (HZ) can cause substantial patient morbidity and lead to large healthcare costs. However, the disease burden of HZ in Southeast Asia may be underestimated. This study aimed to estimate the public health burden of HZ and the impact of vaccinating adults aged ≥ 50 years old in five Southeast Asian countries (Indonesia, Malaysia, Philippines, Thailand, and Vietnam), with adjuvanted recombinant zoster vaccine (RZV) compared with no vaccination...
March 17, 2024: Infectious Diseases and Therapy
https://read.qxmd.com/read/38493392/parent-child-associations-in-covid-19-related-preventive-behaviors-and-efficacy-expectations-a-one-year-longitudinal-survey
#5
JOURNAL ARTICLE
Shinya Yoshino, Wai Him Crystal Law, Shinsuke Koike
PURPOSE: It is necessary to identify the variables that explain the variance in preventive behaviors against COVID-19 to increase adolescents' engagement in these behaviors. We focused on efficacy expectations of preventive behaviors and their associations within families. This study examined the associations between efficacy expectations and preventive behaviors, and between adolescents and their parents in terms of efficacy expectations and preventive behaviors. METHODS: A cross-lagged panel model was employed to analyze 281 parent-child pairs consisting of 245 children (118 girls, mean age = 17...
March 15, 2024: Journal of Adolescent Health
https://read.qxmd.com/read/38493371/highlights-of-the-65th-annual-meeting-of-the-american-association-of-physicists-in-medicine
#6
JOURNAL ARTICLE
Sara L Thrower, Brigid A McDonald, Minsun Kim
The 65th annual meeting of the American Association of Physicists in Medicine took place in July 2023 with a theme of "The Art of Science, The Science of Care." We review a sample of the more than 1000 talks and 1600 posters, focusing on a few topics of interest. Recent legislative changes across the country regarding reproductive health care have led to questions about how these regulations may affect your practice. A fantastic multidisciplinary session addressed these issues with experts in the areas of legal, administration, physics, and medicine...
March 14, 2024: Practical Radiation Oncology
https://read.qxmd.com/read/38493358/a-loss-of-function-mutation-in-cldn25-causing-pelizaeus-merzbacher-like-leukodystrophy
#7
JOURNAL ARTICLE
Yosuke Hashimoto, Claude Besmond, Nathalie Boddaert, Arnold Munnich, Matthew Campbell
Claudin-25 (CLDN-25), also known as Claudin containing domain 1, is an uncharacterized claudin family member. It has less conserved amino acid sequences when compared to other claudins. It also has a very broad tissue expression profile and there is currently a lack of functional information from murine knockout models. Here, we report a de novo missense heterozygous variant in CLDN25 (c. 745G>C, p. A249P) found in a patient diagnosed with Pelizaeus-Merzbacher-like leukodystrophy and presenting with symptoms such as delayed motor development, several episodes of tonic absent seizures and generalized dystonia...
March 17, 2024: Human Molecular Genetics
https://read.qxmd.com/read/38493340/translational-bioinformatics-and-data-science-for-biomarker-discovery-in-mental-health-an-analytical-review
#8
JOURNAL ARTICLE
Krithika Bhuvaneshwar, Yuriy Gusev
Translational bioinformatics and data science play a crucial role in biomarker discovery as it enables translational research and helps to bridge the gap between the bench research and the bedside clinical applications. Thanks to newer and faster molecular profiling technologies and reducing costs, there are many opportunities for researchers to explore the molecular and physiological mechanisms of diseases. Biomarker discovery enables researchers to better characterize patients, enables early detection and intervention/prevention and predicts treatment responses...
January 22, 2024: Briefings in Bioinformatics
https://read.qxmd.com/read/38493337/protecting-the-last-line-of-defense-analytical-approaches-for-sample-preparation-and-determination-of-the-reserve-group-of-antibiotics-in-the-environment
#9
REVIEW
Joanna Wilk, Sylwia Bajkacz
Drug resistance in microorganisms is a serious threat to life and health due to the limited number of antibiotics that show efficacy in treating infections and the difficulty in discovering new compounds with antibacterial activity. To address this issue, the World Health Organization created the AWaRe classification, a tool to support global and national antimicrobial stewardship programs. The AWaRe list categorizes antimicrobials into three groups - Access, Watch, and Reserve - according to their intended use...
March 17, 2024: Critical Reviews in Analytical Chemistry
https://read.qxmd.com/read/38493317/tele-urology-in-the-era-of-covid-19-an-experience-of-the-reconstructive-urology-department-in-iran
#10
JOURNAL ARTICLE
Jalil Hosseini, Amir Hossein Eslami, Shahrzad Nematollahi, Rayka Sharifian, Arezoo Sheikh Milani, Alireza Fatemi
INTRODUCTION: The outbreak of coronavirus has put additional pressure on the health care systems of many countries; but telemedicine can be an important way to deal with it, especially for people whose health has been affected by the virus. The present study aims to investigate the Implementation of a Tele-urology Program for Reconstructive Urologic Referrals: Initial Results and Patient Satisfaction. MATERIAL AND METHODS: All patients with a history of a urethral reconstructive surgery during last year was entered to our study and two nurses collected data of demographic and past medical history of patients by existed...
March 17, 2024: Urology Journal
https://read.qxmd.com/read/38493312/crosstalk-between-covid-19-and-the-gut-brain-axis-a-gut-feeling
#11
JOURNAL ARTICLE
Nida Kalam, Vinod R M T Balasubramaniam
The microbes in the gut are crucial for maintaining the body's immune system and overall gut health. However, it is not fully understood how an unstable gut environment can lead to more severe cases of SARS-CoV-2 infection. The gut microbiota also plays a role in the gut-brain axis and interacts with the central nervous system through metabolic and neuroendocrine pathways. The interaction between the microbiota and the host's body involves hormonal, immune, and neural pathways, and any disruption in the balance of gut bacteria can lead to dysbiosis, which contributes to pathogen growth...
March 16, 2024: Postgraduate Medical Journal
https://read.qxmd.com/read/38493290/satisfaction-with-clinical-pathway-implementation-versus-job-performance-of-clinicians-empirical-evidence-on-the-mediating-role-of-work-engagement-from-public-hospitals-in-sichuan-china
#12
JOURNAL ARTICLE
Junlong Li, Lu Ao, Jay Pan
BACKGROUND: The job performance of clinicians is a clear indicator of both hospital capacity and the level of hospital service. It plays a crucial role in maintaining the effectiveness and quality of medical care. Clinical pathways are a systematic method of quality improvement successfully recommended by broader healthcare systems. Since clinicians play a key role in implementing clinical pathways in public hospitals, this study aims to investigate the effect of the satisfaction of clinicians in public hospitals with clinical pathway implementation on their job performance...
March 16, 2024: BMC Health Services Research
https://read.qxmd.com/read/38493289/hematological-parameters-in-patients-with-recurrent-aphthous-stomatitis-a-systematic-review-and-meta-analysis
#13
JOURNAL ARTICLE
Tahoora Mousavi, Hossein Jalali, Mahmood Moosazadeh
OBJECTIVES: Recurrent Aphthous Stomatitis (RAS) known as recurrent aphthous ulcer is a common and painful ulcerations in oral cavity. It has been suggested that hematological parameters seems to be considered as an etiologic factor. So, this meta-analysis and systematic review was aimed to examine the relationship between RAS and hematological parameters. METHODS: Relevant studies were found using online international databases including Scopus, Science direct, Web of science (ISI), PubMed, and Google Scholar search engine between 2000 and October 2023...
March 16, 2024: BMC Oral Health
https://read.qxmd.com/read/38493283/mindfulness-based-stress-reduction-for-symptom-management-in-older-individuals-with-hiv-associated-neurocognitive-disorder
#14
JOURNAL ARTICLE
Judith T Moskowitz, Brijesh Sharma, Shireen Javandel, Patricia Moran, Robert Paul, Victor De Gruttola, Dimitre Tomov, Haleem Azmy, Rodrigo Sandoval, Madeline Hillis, Karen P Chen, Torie Tsuei, Elizabeth L Addington, Peter D Cummings, Joanna Hellmuth, Isabel Elaine Allen, Beau M Ances, Victor Valcour, Benedetta Milanini
The growing number of people aging with HIV represents a group vulnerable to the symptom burdens of HIV-associated neurocognitive disorder (HAND). Among younger groups, Mindfulness-Based Stress Reduction (MBSR) has been shown to help people living with HIV manage HIV-related and other life stress, and although there is some theoretical and empirical evidence that it may be effective among those with cognitive deficits, the approach has not been studied in older populations with HAND. Participants (n = 180) 55 years or older with HIV and cognitive impairment were randomly assigned to either an 8-week MBSR arm or a waitlist control...
March 16, 2024: AIDS and Behavior
https://read.qxmd.com/read/38493159/screening-for-lung-cancer-with-computed-tomography-protocol-for-systematic-reviews-for-the-canadian-task-force-on-preventive-health-care
#15
JOURNAL ARTICLE
Jennifer Pillay, Sholeh Rahman, Scott Klarenbach, Donna L Reynolds, Laure A Tessier, Guylène Thériault, Nav Persaud, Christian Finley, Natasha Leighl, Matthew D F McInnes, Chantelle Garritty, Gregory Traversy, Maria Tan, Lisa Hartling
PURPOSE: Lung cancer is the leading cause of cancer deaths in Canada, and because early cancers are often asymptomatic screening aims to prevent mortality by detecting cancer earlier when treatment is more likely to be curative. These reviews will inform updated recommendations by the Canadian Task Force on Preventive Health Care on screening for lung cancer. METHODS: We will update the review on the benefits and harms of screening with CT conducted for the task force in 2015 and perform de novo reviews on the comparative effects between (i) trial-based selection criteria and use of risk prediction models and (ii) trial-based nodule classification and different nodule classification systems and on patients' values and preferences...
March 16, 2024: Systematic Reviews
https://read.qxmd.com/read/38493117/the-utilization-of-decision-trees-on-orthopantomographic-and-lateral-panoramic-graphs-for-the-diagnosis-of-unilateral-anterior-disc-displacement-of-the-temporomandibular-joint
#16
JOURNAL ARTICLE
Muhammed Enes Naralan, Binali Cakir, Kaan Orhan
BACKGROUND: Investigation is to utilize decision trees in conjunction with orthopantomography (OPT) and lateral panoramic graphy (LPG) to diagnose unilateral anterior disc displacement (ADD) of the temporomandibular joint. METHODS: In this study, 161 patients with images obtained through all three imaging methods, MRI, OPT, and LPG, were selected from the archives. The participants were categorized into two groups: the study group, comprising 89 patients with unilateral anterior disc displacement, and the control group, consisting of 72 healthy individuals...
March 16, 2024: BMC Oral Health
https://read.qxmd.com/read/38493112/the-assessment-of-preschool-children-with-essence-symptoms-concordance-between-parents-preschool-teachers-and-child-psychologists
#17
JOURNAL ARTICLE
B M Gustafsson, M Sund Levander
BACKGROUND: It is important to detect children with Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations (ESSENCE) in order to implement early intervention and support for the child and family. Standardized instruments for assessment in different contexts of behaviour problems, engagement and psychosocial health obtain an objective picture of the preschool child's mental health. AIM: To explore and compare parents', preschool teachers' and child health care psychologists' assessment of behaviour, everyday function, engagement, social interaction and psychosocial health in children with ESSENCE symptoms...
March 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38493097/effect-of-transporting-oreochromis-niloticus-in-water-with-and-without-sodium-chloride-on-skin-morphology-and-some-immunity-related-genes-expression
#18
JOURNAL ARTICLE
Heba Naeim Sadek Hana, Mohamed Abd El Aziz Ahmed Abd El Galil, Mohamed Abd Allah Mousa, Rasha S B El-Lateif, Arafah M Emam
The aim of this study was to examine the effects of salt addition on the skin gene expression of Mucin, Antimicrobial peptides, cortisol, and glucose in Oreochromis niloticus after 5-hour transportation in water. Three groups were compared: Control, post-transport without salt (PT-S), and post-transport with 5 g salt-1(PT + S), with a stocking density of 28.6 gL-1, 20 fish for each experimental group. The results showed that the PT-S group had more significant changes in gene expression than the PT + S group, suggesting that salt alleviated the stress and immune responses of O...
March 16, 2024: BMC Veterinary Research
https://read.qxmd.com/read/38493083/performance-of-cone-beam-computed-tomography-cbct-in-comparison-to-conventional-computed-tomography-ct-and-magnetic-resonance-imaging-mri-for-the-detection-of-bone-invasion-in-oral-squamous-cell-cancer-oscc-a-prospective-study
#19
JOURNAL ARTICLE
Anton Straub, Christian Linz, Constantin Lapa, Stefan Hartmann, Alexander C Kübler, Urs D A Müller-Richter, Julian Faber, Thorsten Bley, Joachim Brumberg, Olivia Kertels, Roman C Brands
BACKGROUND: Oral squamous carcinoma (OSCC) is often diagnosed at late stages and bone erosion or invasion of the jawbone is frequently present. Computed tomography (CT) and magnetic resonance imaging (MRI) are known to have high diagnostic sensitivities, specificities, and accuracies in detecting these bone affections in patients suffering from OSCC. To date, the existing data regarding the impact of cone-beam computed tomography (CBCT) have been weak. Therefore, this study aimed to investigate whether CBCT is a suitable tool to detect bone erosion or invasion in patients with OSCC...
March 16, 2024: BMC Oral Health
https://read.qxmd.com/read/38493082/associations-of-physical-activity-intensity-frequency-duration-and-volume-with-the-incidence-of-sarcopenia-in-middle-aged-and-older-adults-a-4-year-longitudinal-study-in-china
#20
JOURNAL ARTICLE
Xiaoguang Zhao, Dongxue Liu, Hongjun Zhang, Shaoshuai Shen, Naipeng Zhang, Yihan Pan, Chao Fu, Wenjiao Wang, Hang Ren, Xiaopeng Pan
BACKGROUND: Physical activity (PA) plays an important role in the process of several chronic diseases. It may be also associated with the incidence of sarcopenia. This study aimed to determine the association of PA from different components including frequency, duration, intensity, and volume with the incidence of sarcopenia in middle-aged and older adults. METHODS: This study used data from the China Health and Retirement Longitudinal Study in 2011 and 2015. A total of 3,760 individuals aged ≥ 40 years were involved in this study...
March 16, 2024: BMC Geriatrics
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