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https://www.readbyqxmd.com/read/28795892/cold-atmospheric-pressure-plasma-for-treatment-of-chronic-wounds-drug-or-medical-device
#1
A Kramer, B R Conway, K Meissner, F Scholz, B H Rauch, A Moroder, A Ehlers, A J Meixner, C-D Heidecke, L I Partecke, M Kietzmann, O Assadian
OBJECTIVE: The use of cold atmospheric pressure plasma (CAPP) as a new therapeutic option to aid the healing of chronic wounds appears promising. Currently, uncertainty exists regarding their classification as medical device or medical drug. Because the classification of CAPP has medical, legal, and economic consequences as well as implications for the level of preclinical and clinical testing, the correct classification is not an academic exercise, but an ethical need. METHOD: A multidisciplinary team of physicians, surgeons, pharmacists, physicists and lawyers has analysed the physical and technical characteristics as well as legal conditions of the biological action of CAPP...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28795887/cold-atmospheric-pressure-plasmas-exhibit-antimicrobial-properties-against-critical-bacteria-and-yeast-species
#2
C Wiegand, S Fink, U-C Hipler, O Beier, K Horn, A Pfuch, A Schimanski, B Grünler
OBJECTIVE: Cold atmospheric pressure plasmas (CAPPs) have been used to sterilise implant materials and other thermally unstable medical products and to modify chemical surfaces. This study investigates the antimicrobial effect of the gas and input power used to generate CAPPs on microorganisms causing skin infections, such as Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans and Malassezia pachydermatis. METHOD: Microorganisms were cultivated on Mueller Hinton 2 (MH2) agar plates...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28751756/knowledge-or-noise-making-sense-of-general-practitioners-and-consultant-use-of-2-week-wait-referrals-for-suspected-cancer
#3
Conan Donnelly, Nigel Hart, Alan David McCrorie, Lesley Anderson, Michael Donnelly, Peter Murchie, Anna Gavin
BACKGROUND: Early diagnosis and treatment of cancer is the goal of the 2-week-wait referral pathway (2WW). Variation exists between General Practice use of 2WW and rates of consultant reprioritisation of GP referral from routine to 2WW (Consultant Upgrade). We investigated variation in General Practice and Consultant Upgrade 2WW referral activity. METHODS: Data from 185 000 referrals and 29 000 cancers recorded between 2011 and 2013 from the Northern Ireland Cancer Waiting Time database (CaPPS) were analysed to ascertain standardised referral rate ratios, detection rate (DR) (=sensitivity) and conversion rate (CR) (=positive predictive value) for Practice 2WW referrals and Consultant Upgrade 2WW...
July 27, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28749547/comparing-the-lexical-similarity-of-the-triarchic-model-of-psychopathy-to-contemporary-models-of-psychopathy
#4
Dylan T Gatner, Kevin S Douglas, Stephen D Hart
OBJECTIVE: The Triarchic model of psychopathy (Patrick, Fowles, & Krueger, 2009) posits that psychopathic personality comprises three domains: Boldness, Meanness, and Disinhibition. The present study aimed to clarify conceptual overlap between contemporary definitions of psychopathy, with particular emphasis given to the relevance of Boldness (i.e., social dominance, venturesomeness, emotional resiliency)-a topic of recent debate. METHOD: Undergraduate students (N = 439) compared the lexical similarity of Triarchic domains with two contemporary models of psychopathy: the Comprehensive Assessment of Psychopathic Personality (CAPP; Cooke, Hart, Logan, & Michie, 2012) and Five Factor Model of psychopathy (FFM; Widiger & Lynam, 1998)...
July 27, 2017: Journal of Personality
https://www.readbyqxmd.com/read/28723543/necroptosis-last-message-in-a-bubble
#5
Peter Vandenabeele, Franck Riquet, Benjamin Cappe
RIPK3 kinase-mediated phosphorylation of MLKL pseudokinase is the execution event of necroptosis. Two independent reports-in Immunity (Yoon et al., 2017) and Cell (Gong et al., 2017)-reveal that MLKL affects homeostatic membrane trafficking and necroptosis-enhanced bubble formation involving interaction with the ESCRT machinery.
July 18, 2017: Immunity
https://www.readbyqxmd.com/read/28710598/reflections-for-clinical-pastoral-education-students-in-psychiatric-settings
#6
Nathan Carlin
This article focuses on Donald Capps's books on mental illness. In doing so I highlight three key insights from Capps that I have applied in my own ministry with persons with mental illness in various psychiatric hospitals. These insights, together with my own experience as a chaplain, lead to three practical lessons for clinical pastoral education students in psychiatric settings. I provide some context for my interest in mental illness and my friendship with Capps, as well as some background regarding how Capps's writings on mental illness fit with certain broader themes in his own work as a pastoral theologian...
July 14, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28708029/effect-of-surface-roughness-in-model-and-fresh-fruit-systems-on-microbial-inactivation-efficacy-of-cold-atmospheric-pressure-plasma
#7
Siddharth Bhide, Deepti Salvi, Donald W Schaffner, Mukund V Karwe
This study investigates the efficacy of cold atmospheric pressure plasma (CAPP) on microbial inactivation as influenced by surface roughness of two types of surfaces: sandpaper and fresh fruit peel. Different grits of closed-coat sandpaper were selected, with their roughness (Pq) values ranging from 6 to 16 μm. Apple, orange, and cantaloupe peels were selected for roughness values that were similar to the sandpapers. The sandpapers and the fruit peel surfaces were spot inoculated with Enterobacter aerogenes (10(9) CFU/63...
July 14, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28661998/description-and-yield-of-current-quality-and-safety-review-in-selected-us-academic-emergency-departments
#8
Richard Thomas Griffey, Ryan M Schneider, Brian R Sharp, Jeffrey J Pothof, Sheridan Hodkins, Roberta Capp, Jennifer L Wiler, Neil Sreshta, John E Sather, Christopher S Sampson, Jonathan T Powell, Kathryn Y Groner, Lee M Adler
OBJECTIVES: Quality and safety review for performance improvement is important for systems of care and is required for US academic emergency departments (EDs). Assessment of the impact of patient safety initiatives in the context of increasing burdens of quality measurement compels standardized, meaningful, high-yield approaches for performance review. Limited data describe how quality and safety reviews are currently conducted and how well they perform in detecting patient harm and areas for improvement...
June 29, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28631923/influence-of-ingesting-a-flavonoid-rich-supplement-on-the-metabolome-and-concentration-of-urine-phenolics-in-overweight-obese-women
#9
David C Nieman, Sivapriya Ramamoorthy, Colin D Kay, Courtney L Goodman, Christopher R Capps, Zack L Shue, Nicole Heyl, Mary H Grace, Mary A Lila
This study evaluated the effect of ingesting a flavonoid-rich supplement (329 mg/d) on total urine phenolics and shifts in plasma metabolites in overweight/obese female adults using untargeted metabolomics procedures. Participants (N = 103, 18-65 y, BMI ≥ 25 kg/m(2)) were randomized to flavonoid (F) or placebo (P) groups for 12 weeks with blood and 24 h urine samples collected prestudy and after 4 and 12 weeks in a parallel design. Supplements were prepared as chewable tablets and included vitamin C, wild bilberry fruit extract, green tea leaf extract, quercetin, caffeine, and omega 3 fatty acids...
June 30, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28628075/using-the-nln-faculty-preparation-for-global-experiences-toolkit-for-successful-application-for-the-fulbright-scholar-award
#10
Zepure Samawi, Lisa Capps, Ruth Hansen
With an increasingly global world and the migration of diverse populations, nurse faculty have opportunities to learn and share varied perspectives through involvement internationally in research, teaching, and practice. The National League for Nursing (NLN) joins with the World Health Organization and the International Council of Nurses to promote international nursing standards. One way in which nursing faculty can contribute to this goal is by pursuing international education, research, and service as a Fulbright scholar...
July 2017: Nursing Education Perspectives
https://www.readbyqxmd.com/read/28618883/the-freedom-of-the-octogenarian-to-find-grace-and-humor-in-the-lasting-personal-strength-gained-through-cappe-education
#11
Maureen Soukoreff
No abstract text is available yet for this article.
June 2017: Journal of Pastoral Care & Counseling: JPCC
https://www.readbyqxmd.com/read/28573356/active-involved-community-partnerships-co-creating-implementation-infrastructure-for-getting-to-and-sustaining-social-impact
#12
Renée I Boothroyd, Aprille Y Flint, A Mark Lapiz, Sheryl Lyons, Karen Lofts Jarboe, William A Aldridge
Active involved community partnerships (AICPs) are essential to co-create implementation infrastructure and translate evidence into real-world practice. Across varied forms, AICPs cultivate community and tribal members as agents of change, blending research and organizational knowledge with relationships, context, culture, and local wisdom. Unlike selective engagement, AICPs enable active involvement of partners in the ongoing process of implementation and sustainability. This includes defining the problem, developing solutions, detecting practice changes, aligning organizational supports, and nurturing shared responsibility, accountability, and ownership for implementation...
June 1, 2017: Translational Behavioral Medicine
https://www.readbyqxmd.com/read/28557593/effects-of-low-level-laser-therapy-on-the-modulation-of-tissue-temperature-and-hyperalgesia-following-a-partial-achilles-tendon-injury-in-rats
#13
Cid André Fidelis de Paula Gomes, Almir Vieira Dibai-Filho, Rodney Capp Pallotta, Evela Aparecida Pereira da Silva, Anna Cristina de Farias Marques, Rodrigo Labat Marcos, Paulo de Tarso Camillo de Carvalho
The aim of the present study was to evaluate the effects of low-level laser therapy (LLLT) on the modulation of tissue temperature and hyperalgesia following a partial injury to the Achilles tendon in rats. Forty-five rats were randomly divided into three groups: a control group, a group treated with LLLT at a dose of 1.4 J (808 nm, 50 mW, 1.4 J), and a group treated with LLLT at a dose of 2.1 J (808 nm, 50 mW, 2.1 J). LLLT was administered to a single point immediately following the partial injury of the Achilles tendon...
May 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28537366/variation-in-methods-used-to-determine-national-mean-dmft-scores-for-12-year-old-children-in-european-countries
#14
R N Patel, K A Eaton, N B Pitts, A Schulte, K Pieper, S White
Aim: The aim of this study was to investigate the methods used to identify national mean DMFT scores for 12-year-old children in all the Member States of the European Union and European Economic Area, and in 11 other European countries. Methods: The most recent national mean DMFT scores were accessed from the World Health Organisation Oral Health CAPP and the Council of European Chief Dental Officers databanks. A literature search was then performed to access the reports of the studies that had produced these DMFT scores, cited on these databanks...
December 2016: Community Dental Health
https://www.readbyqxmd.com/read/28452956/protective-effect-of-caffeic-acid-derivatives-on-tert-butyl-hydroperoxide-induced-oxidative-hepato-toxicity-and-mitochondrial-dysfunction-in-hepg2-cells
#15
Tzung-Hsun Tsai, Chun-Hsien Yu, Yu-Ping Chang, Yu-Ting Lin, Ching-Jang Huang, Yueh-Hsiung Kuo, Po-Jung Tsai
Oxidative stress results in structural and functional abnormalities in the liver and is thought to be a crucial factor in liver diseases. The aim of this study was to investigate the cytoprotective and antioxidant effects of caffeic acid (CA) derivatives on tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in HepG2 cells. Nine CA derivatives were synthesized, including N-phenylethyl caffeamide (PECA), N-(3-florophen)methyl caffeamide (FMCA), N-(4-methoxy-phen)methyl caffeamide (MPMCA), N-heptyl caffeamide (HCA), N-octyl caffeamide (OCA), octyl caffeate (CAOE), phenpropyl caffeate (CAPPE), phenethyl caffeate (CAPE), and phenmethyl caffeate (CAPME)...
April 28, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28430249/study-of-a-reflection-grating-used-in-littrow-mount
#16
D M Capps
The near and far fields of a finite conductivity metallic grating with symmetrical triangular facets, used in Littrow mount, are studied. A new Green's function approach, based on the Hertz vector, is introduced and used to propagate throughout a two-dimensional domain. The field quantity of primary interest is Poynting's vector; however, the stored power is also calculated. In assessing the fields generated by the propagator, a quasi-periodic dependence of output characteristics on the grating depth to period ratio, discussed in the literature, is also found in the present study...
April 20, 2017: Applied Optics
https://www.readbyqxmd.com/read/28408878/reward-based-motor-adaptation-mediated-by-basal-ganglia
#17
Taegyo Kim, Khaldoun C Hamade, Dmitry Todorov, William H Barnett, Robert A Capps, Elizaveta M Latash, Sergey N Markin, Ilya A Rybak, Yaroslav I Molkov
It is widely accepted that the basal ganglia (BG) play a key role in action selection and reinforcement learning. However, despite considerable number of studies, the BG architecture and function are not completely understood. Action selection and reinforcement learning are facilitated by the activity of dopaminergic neurons, which encode reward prediction errors when reward outcomes are higher or lower than expected. The BG are thought to select proper motor responses by gating appropriate actions, and suppressing inappropriate ones...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28406176/male-alliance-behaviour-and-mating-access-varies-with-habitat-in-a-dolphin-social-network
#18
Richard C Connor, William R Cioffi, Srđan Randić, Simon J Allen, Jana Watson-Capps, Michael Krützen
Within-species variation in social structure has attracted interest recently because of the potential to explore phenotypic plasticity and, specifically, how demographic and ecological variation influence social structure. Populations of bottlenose dolphins (Tursiops spp.) vary in male alliance formation, from no alliances to simple pairs to, in Shark Bay, Western Australia, the most complex nested alliances known outside of humans. Examination of ecological contributions to this variation is complicated by differences among populations in other potentially explanatory traits, such as phylogenetic distance, as well as female reproductive schedules, sexual size dimorphism, and body size...
April 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28399596/antral-follicles-count-and-anti-m%C3%A3-llerian-hormone-levels-after-gonadotoxic-chemotherapy-in-patients-with-breast-cancer-cohort-study
#19
Ângela Marcon D'Avila, Edison Capp, Helena von Eye Corleta
Aim To assess ovarian reserve (OVR) by means of follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and antral follicle count (AFC) measurement in eumenorrheic women with breast cancer, exposed to gonadotoxic chemotherapy. Method Fifty-two women (35.3 ± 3.8 years old) with breast cancer and undergoing cyclophosphamide-containing chemotherapy were enrolled. The assessment was performed before chemotherapy (T1) and after 2 (T2) and 6 months (T3). Results Six months after chemotherapy, the prevalence of regular cycles was 60%...
April 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28399311/molecular-markers-of-pesticide-resistance-and-pathogens-in-human-head-lice-phthiraptera-pediculidae-from-rural-georgia-usa
#20
Marina E Eremeeva, Danielle Capps, Emmanuel B Winful, Shamta S Warang, Sarah E Braswell, Nikolay K Tokarevich, Denise L Bonilla, Lance A Durden
Although the head louse, Pediculus humanus capitis De Geer, and body louse, Pediculus humanus humanus L., both have a worldwide distribution, the occurrence of head louse pediculosis appears to be more prevalent in modern societies despite systematic use of various pediculicides. This study tested head lice collected in rural Georgia and body lice collected in Russia for the prevalence of a kdr-biomarker that is associated with permethrin resistance. This study also screened lice for the presence of DNA from Bartonella quintana and Acinetobacter species...
March 2, 2017: Journal of Medical Entomology
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