keyword
MENU ▼
Read by QxMD icon Read
search

CAPP

keyword
https://www.readbyqxmd.com/read/28212416/the-variability-of-multisensory-processes-of-natural-stimuli-in-human-and-non-human-primates-in-a-detection-task
#1
Cécile Juan, Céline Cappe, Baptiste Alric, Benoit Roby, Sophie Gilardeau, Pascal Barone, Pascal Girard
BACKGROUND: Behavioral studies in both human and animals generally converge to the dogma that multisensory integration improves reaction times (RTs) in comparison to unimodal stimulation. These multisensory effects depend on diverse conditions among which the most studied were the spatial and temporal congruences. Further, most of the studies are using relatively simple stimuli while in everyday life, we are confronted to a large variety of complex stimulations constantly changing our attentional focus over time, a modality switch that can impact on stimuli detection...
2017: PloS One
https://www.readbyqxmd.com/read/28198846/femtosecond-two-photon-laser-induced-fluorescence-of-krypton-for-high-speed-flow-imaging
#2
Yejun Wang, Cade Capps, Waruna D Kulatilaka
Ultrashort-pulse (femtosecond-duration) two-photon laser-induced fluorescence (fs-TPLIF) of an inert gas tracer krypton (Kr) is investigated. A detailed spectroscopic study of fluorescence channels followed by the 5p<sup>'</sup>←←4p excitation of Kr at 204.1 nm is reported. The experimental line positions in the 750-840 nm emission region agree well with the NIST Atomic Spectra Database. The present work provides an accurate listing of relative line strengths in this spectral region. In the range of laser pulse energies investigated, a quadratic dependence was observed between the Kr-TPLIF signal and the laser pulse energy...
February 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28146475/mega-evolutionary-dynamics-of-the-adaptive-radiation-of-birds
#3
Christopher R Cooney, Jen A Bright, Elliot J R Capp, Angela M Chira, Emma C Hughes, Christopher J A Moody, Lara O Nouri, Zoë K Varley, Gavin H Thomas
The origin and expansion of biological diversity is regulated by both developmental trajectories and limits on available ecological niches. As lineages diversify, an early and often rapid phase of species and trait proliferation gives way to evolutionary slow-downs as new species pack into ever more densely occupied regions of ecological niche space. Small clades such as Darwin's finches demonstrate that natural selection is the driving force of adaptive radiations, but how microevolutionary processes scale up to shape the expansion of phenotypic diversity over much longer evolutionary timescales is unclear...
February 16, 2017: Nature
https://www.readbyqxmd.com/read/28141671/community-health-workers-addressing-client-objectives-among-frequent-emergency-department-users
#4
Bethany M Kwan, Amy Rockwood, Brian Bandle, Douglas Fernald, Mika K Hamer, Roberta Capp
OBJECTIVES: To evaluate effectiveness of a community health worker (CHW) program designed to address client objectives among frequent emergency department (ED) users. DESIGN: Program evaluation using secondary analysis of client objectives from program records. Client objectives were characterized according to the World Health Organization's social determinants of health framework. Hierarchical generalized linear modeling was used to assess factors associated with objective achievement...
January 30, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28129409/justice-is-the-missing-link-in-one-health-results-of-a-mixed-methods-study-in-an-urban-city-state
#5
Tamra Lysaght, Benjamin Capps, Michele Bailey, David Bickford, Richard Coker, Zohar Lederman, Sangeetha Watson, Paul Anantharajah Tambyah
BACKGROUND: One Health (OH) is an interdisciplinary collaborative approach to human and animal health that aims to break down conventional research and policy 'silos'. OH has been used to develop strategies for zoonotic Emerging Infectious Diseases (EID). However, the ethical case for OH as an alternative to more traditional public health approaches is largely absent from the discourse. To study the ethics of OH, we examined perceptions of the human health and ecological priorities for the management of zoonotic EID in the Southeast Asia country of Singapore...
2017: PloS One
https://www.readbyqxmd.com/read/28120925/mechanistic-insights-into-the-impact-of-cold-atmospheric-pressure-plasma-on-human-epithelial-cell-lines
#6
Marlène Dezest, Laurent Chavatte, Marion Bourdens, Damien Quinton, Mylène Camus, Luc Garrigues, Pascal Descargues, Stéphane Arbault, Odile Burlet-Schiltz, Louis Casteilla, Franck Clément, Valérie Planat, Anne-Laure Bulteau
Compelling evidence suggests that Cold Atmospheric Pressure Plasma (CAPP) has potential as a new cancer therapy. However, knowledge about cellular signaling events and toxicity subsequent to plasma treatment is still poorly documented. The aim of this study was to focus on the interaction between 3 different types of plasma (He, He-O2, He-N2) and human epithelial cell lines to gain better insight into plasma-cell interaction. We provide evidence that reactive oxygen and nitrogen species (RONS) are inducing cell death by apoptosis and that the proteasome, a major intracellular proteolytic system which is important for tumor cell growth and survival, is a target of (He or He-N2) CAPP...
January 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28120813/control-of-spontaneous-emission-of-quantum-dots-using-correlated-effects-of-metal-oxides-and-dielectric-materials
#7
S M Sadeghi, W J Wing, R R Gutha, L Capps
We study the emission dynamics of semiconductor quantum dots in the presence of the correlated impact of metal oxides and dielectric materials. For this we used layered material structures consisting of a base substrate, a dielectric layer, and an ultrathin layer of a metal oxide. After depositing colloidal CdSe/ZnS quantum dots on the top of the metal oxide, we used spectral and time-resolved techniques to show that, depending on the type and thickness of the dielectric material, the metal oxide can characteristically change the interplay between intrinsic excitons, defect states, and the environment, offering new material properties...
January 25, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28106554/recovery-from-proactive-semantic-interference-in-mild-cognitive-impairment-and-normal-aging-relationship-to-atrophy-in-brain-regions-vulnerable-to-alzheimer-s-disease
#8
David A Loewenstein, Rosie E Curiel, Clinton Wright, Xiaoyan Sun, Noam Alperin, Elzabeth Crocco, Sara J Czaja, Arlene Raffo, Ailyn Penate, Jose Melo, Kimberly Capp, Monica Gamez, Ranjan Duara
BACKGROUND: There is growing evidence that proactive semantic interference (PSI) and failure to recover from PSI may represent early features of Alzheimer's disease (AD). OBJECTIVE: This study investigated the association between PSI, recovery from PSI, and reduced MRI volumes in AD signature regions among cognitively impaired and unimpaired older adults. METHODS: Performance on the LASSI-L (a novel test of PSI and recovery from PSI) and regional brain volumetric measures were compared between 38 cognitively normal (CN) elders and 29 older participants with amnestic mild cognitive impairment (MCI)...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28063736/brilliant-cresyl-blue-staining-does-not-present-cytotoxic-effects-on-human-luteinized-follicular-cells-according-to-gene-protein-expression-as-well-as-to-cytotoxicity-tests
#9
Diego Duarte Alcoba, Júlia Schneider, Letícia Arruda, Patrícia Borba Martiny, Edison Capp, Helena von Eye Corleta, Ilma Simoni Brum
In vitro oocyte maturation presents many advantages and its success is related to the selection of fully grown oocytes. In animal models, staining of cumulus-oocyte complexes (COCs) with Brilliant Cresyl Blue (BCB) is widely used for this selection. However, a lack of information about the safety of BCB makes its applicability in humans questionable. Because granulosa and cumulus cells have a close relationship with the oocyte and taking into account that follicular cells are also exposed to BCB when this pre-selection method is applied, we aimed to evaluate the effects of BCB on human follicular cells exposed to BCB...
January 4, 2017: Reproductive Biology
https://www.readbyqxmd.com/read/28052327/tissue-disruption-increases-stochastic-gene-expression-thus-producing-tumours-cancer-initiation-without-driver-mutation
#10
REVIEW
Jean-Pascal Capp
Cancer research produced many paradoxical results in recent years. The reductionist approach now shows its limits. Considering the origin of the disease at the tissue level and increased stochastic gene expression (SGE) as a driving force, while admitting a role for genetic alterations in cancer progression, might solve these contradictions. Undifferentiated cells are characterized by open and accessible chromatin generating global and highly SGE (high expression noise) which is a hallmark of pluripotency, while differentiation is associated with progressive chromatin closing and decreased noise...
January 4, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28042027/distant-heterotopic-callosal-connections-to-premotor-cortex-in-non-human-primates
#11
F Lanz, V Moret, R Ambett, C Cappe, E M Rouiller, G Loquet
Cortico-cortical connectivity has become a major focus of neuroscience in the last decade but most of the connectivity studies focused on intrahemispheric circuits. Little has been reported about information acquired and processed in the premotor cortex and its functional connection with its homotopic counterpart in the opposite hemisphere via the corpus callosum. In non-human primates (macaques) lateralization is not well documented and its exact role is still unknown. The present study confirms in two macaques the existence of homotopic contralateral projections and completes the picture by further exploring heterotopic (non-motor) callosal projections...
March 6, 2017: Neuroscience
https://www.readbyqxmd.com/read/28027121/carcinogenesis-of-vulvar-lesions-morphology-and-immunohistochemistry-evaluation
#12
Raquel Camara Rivero, Deborah Garcia, Luciano Serpa Hammes, Marcelle Reesink Cerski, Valentino Magno, Lúcia Maria Kliemann, Edison Capp
OBJECTIVES: The aim of the study was to assess the 2 pathways of vulvar carcinogenesis and correlate immunohistochemical expression of p53 with histopathological findings. MATERIALS AND METHODS: This cross-sectional study included 76 cases. Patients were classified according to the 2004 International Society for the Study of Vulvovaginal Disease Terminology, followed by a review of clinical records and immunohistochemical staining for p53. RESULTS: Fifteen cases were in the human papillomavirus (HPV)-associated pathway (12 cases of usual vulvar intraepithelial neoplasia [VIN] and 3 of warty squamous cell carcinoma [SCC]), and 13 cases were in the HPV-independent pathway (5 cases of differentiated VIN and 8 of keratinizing SCC)...
January 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28008706/consumer-driven-nutrient-dynamics-in-freshwater-ecosystems-from-individuals-to-ecosystems
#13
Carla L Atkinson, Krista A Capps, Amanda T Rugenski, Michael J Vanni
The role of animals in modulating nutrient cycling [hereafter, consumer-driven nutrient dynamics (CND)] has been accepted as an important influence on both community structure and ecosystem function in aquatic systems. Yet there is great variability in the influence of CND across species and ecosystems, and the causes of this variation are not well understood. Here, we review and synthesize the mechanisms behind CND in fresh waters. We reviewed 131 articles on CND published between 1973 and 1 June 2015. The rate of new publications in CND has increased from 1...
December 23, 2016: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/27982035/global-repositioning-of-transcription-start-sites-in-a-plant-fermenting-bacterium
#14
Magali Boutard, Laurence Ettwiller, Tristan Cerisy, Adriana Alberti, Karine Labadie, Marcel Salanoubat, Ira Schildkraut, Andrew C Tolonen
Bacteria respond to their environment by regulating mRNA synthesis, often by altering the genomic sites at which RNA polymerase initiates transcription. Here, we investigate genome-wide changes in transcription start site (TSS) usage by Clostridium phytofermentans, a model bacterium for fermentation of lignocellulosic biomass. We quantify expression of nearly 10,000 TSS at single base resolution by Capp-Switch sequencing, which combines capture of synthetically capped 5' mRNA fragments with template-switching reverse transcription...
December 16, 2016: Nature Communications
https://www.readbyqxmd.com/read/27901618/genome-wide-interaction-analysis-of-air-pollution-exposure-and-childhood-asthma-with-functional-follow-up
#15
Anna Gref, Simon Kebede Merid, Olena Gruzieva, Stéphane Ballereau, Allan Becker, Tom Bellander, Anna Bergström, Yohan Bossé, Matteo Bottai, Moira Chan-Yeung, Elaine Fuertes, Despo Ierodiakonou, Ruiwei Jiang, Stéphane Joly, Meaghan Jones, Michael S Kobor, Michal Korek, Anita L Kozyrskyj, Ashish Kumar, Nathanaël Lemonnier, Elaina MacIntyre, Camille Ménard, David Nickle, Ma'en Obeidat, Johann Pellet, Marie Standl, Annika Sääf, Cilla Söderhäll, Carla Mt Tiesler, Maarten van den Berge, Judith M Vonk, Hita Vora, Cheng-Jian Xu, Josep M Antó, Charles Auffray, Michael Brauer, Jean Bousquet, Bert Brunekreef, W James Gauderman, Joachim Heinrich, Juha Kere, Gerard H Koppelman, Dirkje Postma, Christopher Carlsten, Göran Pershagen, Erik Melén
RATIONALE: The evidence supporting an association between traffic-related air pollution exposure and incident childhood asthma is inconsistent, and may depend on genetic factors. OBJECTIVES: To identify gene-environment interaction effects on childhood asthma using genome-wide single nucleotide polymorphism (SNP) data and air pollution exposure. Identified loci were further analyzed at epigenetic and transcriptomic levels. METHODS: We used land use regression models to estimate individual air pollution exposure (represented by outdoor NO2 levels) at the birth address and performed a genome-wide interaction study for doctor's diagnosis of asthma up to 8 years in three European birth cohorts (n=1,534) with look-up for interaction in two separate North American cohorts, CHS and CAPPS/SAGE (n=1,602 and 186 subjects, respectively)...
November 30, 2016: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27900046/proliferation-and-metastatic-potential-of-endometrial-cancer-cells-in-response-to-metformin-treatment-in-a-high-versus-normal-glucose-environment
#16
Amanda de Barros Machado, Vania Dos Reis, Sebastian Weber, Julia Jauckus, Ilma Simoni Brum, Helena von Eye Corleta, Thomas Strowitzki, Edison Capp, Ariane Germeyer
In order to improve our understanding of the potential preventive and therapeutic role of metformin, the present study aimed to investigate the capability of low-dose metformin in the efficient inhibition of cancer development and the reduction of the metastasis of endometrial adenocarcinoma type I and primary endometrial epithelial cells (eEPs), with the drug acting as a treatment in a hyperinsulinemic environment exposed to high and normal glucose conditions. The Ishikawa endometrial adenocarcinoma cell line and primary eEPs were exposed to an environment with high (17 mM) or normal glucose (5 mM) and treated with insulin, low-dose metformin (0...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27898256/comparative-study-of-the-physiotherapeutic-and-drug-protocol-and-low-level-laser-irradiation-in-the-treatment-of-pain-associated-with-temporomandibular-dysfunction
#17
Marcos Fernando Xisto Braga Cavalcanti, Uoston Holder Silva, Ernesto Cesar Pinto Leal-Junior, Rodrigo A B Lopes-Martins, Rodrigo Labat Marcos, Rodney Capp Pallotta, Francesca Diomede, Oriana Trubiani, Natalia De Isla, Lucio Frigo
BACKGROUND: The temporomandibular joint (TMJ) is a structure of the craniofacial complex affected by neurological diseases. Orthopedic and musculoskeletal changes can also cause temporomandibular disorders (TMD) and pain. Low-level laser (LLL) therapy has been studied in the treatment of temporomandibular jaw (TMJ) dysfunction, and controversial results were obtained. OBJECTIVE: The objective of this work was comparing the physiotherapeutic and drug protocol (PDP) to LLL therapy in the treatment of pain associated with TMD...
December 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27831904/distinct-biological-subtypes-and-patterns-of-genome-evolution-in-lymphoma-revealed-by-circulating-tumor-dna
#18
Florian Scherer, David M Kurtz, Aaron M Newman, Henning Stehr, Alexander F M Craig, Mohammad Shahrokh Esfahani, Alexander F Lovejoy, Jacob J Chabon, Daniel M Klass, Chih Long Liu, Li Zhou, Cynthia Glover, Brendan C Visser, George A Poultsides, Ranjana H Advani, Lauren S Maeda, Neel K Gupta, Ronald Levy, Robert S Ohgami, Christian A Kunder, Maximilian Diehn, Ash A Alizadeh
Patients with diffuse large B cell lymphoma (DLBCL) exhibit marked diversity in tumor behavior and outcomes, yet the identification of poor-risk groups remains challenging. In addition, the biology underlying these differences is incompletely understood. We hypothesized that characterization of mutational heterogeneity and genomic evolution using circulating tumor DNA (ctDNA) profiling could reveal molecular determinants of adverse outcomes. To address this hypothesis, we applied cancer personalized profiling by deep sequencing (CAPP-Seq) analysis to tumor biopsies and cell-free DNA samples from 92 lymphoma patients and 24 healthy subjects...
November 9, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/27818073/vocal-range-in-the-speech-of-users-of-low-dose-oral-contraceptives
#19
Eliséa Maria Meurer, Andressa Dias Moura, Leila Rechenberg, Helena von Eye Corleta, Edison Capp
OBJECTIVE: The study aimed to investigate the vocal range of oral contraceptive (OC) users aged between 20 and 30 years. STUDY DESIGN: This is a cross-sectional study. METHODS: Forty-eight women aged 20-30 years who used low-dose OCs and 24 age-matched women who did not use oral monophasic contraceptives (w/oOC) were enrolled. Acoustic analysis was performed using the Motor Speech Profile program, Model 4341 (Kay Elemetrics Corp). Data were analyzed using generalized estimating equation...
November 3, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27798755/quality-of-life-psychological-characteristics-and-adjustment-in-parents-of-children-with-attention-deficit-hyperactivity-disorder
#20
Emilie Cappe, Mélanie Bolduc, Marie-Caroline Rougé, Marie-Claude Saiag, Richard Delorme
PURPOSE: This study investigated quality of life and adjustment mechanisms in parents of children with Attention-Deficit/Hyperactivity Disorder (ADHD). METHOD: Ninety parents of children with ADHD completed a sociodemographic questionnaire and self-assessment scales to measure their perceived stress, social support, sense of control, coping strategies and quality of life. RESULTS: ADHD in children negatively affected parents' quality of life, especially their psychological well-being and personal fulfillment...
October 31, 2016: Quality of Life Research
keyword
keyword
92407
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"