Carolyn A Young, Amina Chaouch, Christopher J Mcdermott, Ammar Al-Chalabi, Suresh K Chhetri, Kevin Talbot, Timothy Harrower, Richard W Orrell, Joe Annadale, Oliver C Hanemann, Antonio Scalfari, Alan Tennant, Roger Mills
Objective : Dyspnea, or breathlessness, is an important symptom in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND). We examined the measurement properties of the Dyspnea-12. Methods : Rasch analysis enabled conversion of raw Dyspnea-12 scores to interval level metric equivalents. Converted data were used to perform trajectory modeling; those following different trajectories were compared for demographic, clinical, symptom, and functioning characteristics. Logistic regression examined differences between distinct trajectories...
March 11, 2024: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration