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https://www.readbyqxmd.com/read/28637083/changes-in-spiritual-well-being-and-psychological-outcomes-in-ovarian-cancer-survivors
#1
Lauren Z Davis, Michaela Cuneo, Premal H Thaker, Michael J Goodheart, David Bender, Susan Lutgendorf
OBJECTIVE: Because of the poor prognosis of ovarian cancer and concomitant distress, understanding contributors to positive well-being is critical. This study examines spiritual growth as a domain of posttraumatic growth and its contribution to longitudinal emotional outcomes in ovarian cancer. METHODS: Ovarian cancer patients (N=241) completed measures assessing spirituality (FACIT-SP-12; subscales: faith, meaning, and peace), depression (CESD), cancer-specific anxiety (IES), and total mood disturbance (TMD: POMS) prior to surgery and one-year post-surgery...
June 21, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28622815/effects-of-a-brief-ed-based-alcohol-and-violence-intervention-on-depressive-symptoms
#2
Megan L Ranney, Jason Goldstick, Andria Eisman, Patrick M Carter, Maureen Walton, Rebecca M Cunningham
OBJECTIVE: Depressive symptoms frequently co-exist in adolescents with alcohol use and peer violence. This paper's purpose was to examine the secondary effects of a brief alcohol-and-violence-focused ED intervention on depressive symptoms. METHOD: Adolescents (ages 14-18) presenting to an ED for any reason, reporting past year alcohol use and aggression, were enrolled in a randomized control trial (control, therapist-delivered brief intervention [TBI], or computer-delivered brief intervention [CBI])...
May 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28617043/eveningness-is-associated-with-greater-depressive-symptoms-in-type-2-diabetes-patients-a-study-in-two-different-ethnic-cohorts
#3
Sunee Saetung, Hataikarn Nimitphong, Nantaporn Siwasaranond, Areesa Manodpitipong, Stephanie J Crowley, Megan M Hood, Sirimon Reutrakul
BACKGROUND: Eveningness is associated with greater depressive symptoms in the general population. Depression and type 2 diabetes (T2D) commonly coexist. We aimed to explore the association between morningness/eveningness and depressive symptoms in T2D patients in the United States and in Thailand. PARTICIPANTS: T2D patients (n=182) from an endocrinology clinic in Chicago, Illinois and six hospitals in Thailand (n=251) were enrolled. METHODS: Diabetes history was collected...
June 15, 2017: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/28609394/evaluation-of-depressive-symptoms-in-mid-aged-women-report-of-a-multicenter-south-american-study
#4
Danny Salazar-Pousada, Alvaro Monterrosa-Castro, Eliana Ojeda, Sandra C Sánchez, Ingrid F Morales-Luna, Faustino R Pérez-López, Peter Chedraui
OBJECTIVE: To evaluate depressive symptoms and related factors among mid-aged women using the 10-item Center for Epidemiologic Studies Depression Scale (CESD-10). METHODS: This was a cross-sectional multicenter study in which women aged 40 to 65 from various South American countries were surveyed with the CESD-10 and a general questionnaire containing personal and partner data. RESULTS: In all, 864 women were interviewed from Colombia (Afro-Colombian, n = 215), Ecuador (Mestizo, n = 202), Perú (Quechua at high altitude, n = 231), and Paraguay (Mestizo, n = 216)...
June 12, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28603562/meditation-in-stressed-older-adults-improvements-in-self-rated-mental-health-not-paralleled-by-improvements-in-cognitive-function-or-physiological-measures
#5
Barry S Oken, Helané Wahbeh, Elena Goodrich, Daniel Klee, Tabatha Memmott, Meghan Miller, Rongwei Fu
To determine if mindfulness meditation (MM) in older adults improves cognition and, secondarily, if MM improves mental health and physiology, 134 at least mildly stressed 50-85 year olds were randomized to a six-week MM intervention or a waitlist control. Outcome measures were assessed at baseline and two months later at Visit 2. The primary outcome measure was an executive function/attentional measure (flanker task). Other outcome measures included additional cognitive assessments, salivary cortisol, respiratory rate, heart rate variability, Positive and Negative Affect Schedule (PANAS), Center for Epidemiologic Studies Depression (CESD), Perceived Stress Scale (PSS), Neuroticism-Extraversion-Openness (NEO) personality traits, and SF-36 health-related quality of life...
June 2017: Mindfulness
https://www.readbyqxmd.com/read/28601985/poor-early-childhood-outcomes-attributable-to-maternal-depression-in-mexican-women
#6
Filipa de Castro, Jean Marie Place, Aremis Villalobos, Rosalba Rojas, Tonatiuh Barrientos, Edward A Frongillo
We aimed to estimate the population fraction of poor early child health and developmental outcomes attributable to maternal depressive symptoms (DS) contrasting it between low- and middle/high-income households. We used a nationally representative probabilistic sample of 4240 children younger than 5 years old and their mothers, derived from the Mexican National Health and Nutrition Survey Data (ENSANUT 2012). Complex survey design, sampling, and analytic weights were taken into account in analyses. DS was measured by CESD-7...
June 10, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28601589/sharpsports-mental-health-awareness-research-project-prevalence-and-risk-factors-of-depressive-symptoms-and-life-stress-in-elite-athletes
#7
Sarah Beable, Mark Fulcher, Arier C Lee, Bruce Hamilton
OBJECTIVES: Our study aims to estimate the prevalence of symptoms of depression and daily life hassles in elite athletes. DESIGN: A cross-sectional prospective epidemiological study design. METHODS: An online anonymous survey was administered during a 2-month period from May to July 2015. Athletes 18 years of age (or older) who were members of the High Performance Sport New Zealand programme were invited to participate. Of 370 potential participants, 187 completed responses were received (51%)...
May 17, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28597110/acculturation-matters-in-the-relation-between-ambivalence-over-emotional-expressions-and-well-being-among-chinese-american-breast-cancer-survivors
#8
William Tsai, Qian Lu
PURPOSE: Ambivalence over emotional expression (AEE) is the inner conflict of desiring emotion expression and fearing consequence of emotion expression. Few studies to date have examined the effects of AEE within an ethnic group that prioritizes emotional self-control. The present study examined the associations between AEE and well-being (viz., quality of life and depressive symptoms) as a function of acculturation among a sample of Chinese American breast cancer survivors. METHODS: Ninety-six Chinese breast cancer survivors (M age = 54...
June 8, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28527672/quality-of-life-among-long-term-survivors-of-advanced-stage-ovarian-cancer-a-cross-sectional-approach
#9
Susan K Lutgendorf, Eileen Shinn, Jeanne Carter, Susan Leighton, Keith Baggerly, Michele Guindani, Bryan Fellman, Marianne Matzo, George M Slavich, Marc T Goodman, William Tew, Jenny Lester, Kathleen M Moore, Beth Y Karlan, Douglas A Levine, Anil K Sood
PURPOSE: Long-term survival of women with advanced-stage ovarian cancer is relatively rare. Little is known about quality of life (QOL) and survivorship concerns of these women. Here, we describe QOL of women with advanced-stage ovarian cancer surviving for 8.5 years or longer and compare women with 0-1 recurrence to those with multiple recurrences. METHODS: Participants (n=56) recruited from 5 academic medical centers and the Ovarian Cancer Research Fund Alliance completed surveys regarding QOL (FACT-O), mood (CESD), social support (SPS), physical activity (IPAQ-SF), diet, and clinical characteristics...
May 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28465305/effects-of-different-amounts-of-exercise-on-preventing-depressive-symptoms-in-community-dwelling-older-adults-a-prospective-cohort-study-in-taiwan
#10
Yu-Chen Chang, Mei-Chun Lu, I-Han Hu, Wan-Chi Ida Wu, Susan C Hu
OBJECTIVES: To compare the effects of four different amounts of exercise for preventing depressive symptoms in community-dwelling older adults. DESIGN: Prospective cohort study. SETTING: A nationally representative sample in Taiwan. PARTICIPANTS: Four waves of the survey 'Taiwan Longitudinal Study on Aging (TLSA)' from 1996 to 2007 were analysed. A total of 2673 older adults aged 65 years and over were recruited. PRIMARY AND SECONDARY OUTCOME MEASURES: Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale (CESD)...
May 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28436695/the-impact-of-childhood-parental-quality-on-mental-health-outcomes-in-older-adults
#11
R A Burns, V Loh, J E Byles, H L Kendig
OBJECTIVE: Parental bonding is cited as a determinant of mental health outcomes in childhood, adolescence and early-mid adulthood. Examination of the long-term impact for older adults is limited. We therefore examine the long-term risk of perceived poor parental bonding on mental health across the lifespan and into early-old age. METHODS: Participants (N = 1255) were aged 60-64 years of age and drawn from the Australian Life Histories and Health study. Quality of parental bonding was assessed with the Parental Bonding Instrument (PBI)...
April 24, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28401034/targeting-wolman-disease-and-cholesteryl-ester-storage-disease-disease-pathogenesis-and-therapeutic-development
#12
REVIEW
Francis Aguisanda, Natasha Thorne, Wei Zheng
Wolman disease (WD) and cholesteryl ester storage disease (CESD) are lysosomal storage diseases (LSDs) caused by a deficiency in lysosomal acid lipase (LAL) due to mutations in the LIPA gene. This enzyme is critical to the proper degradation of cholesterol in the lysosome. LAL function is completely lost in WD while some residual activity remains in CESD. Both are rare diseases with an incidence rate of less than 1/100,000 births for WD and approximate 2.5/100,000 births for CESD. Clinical manifestation of WD includes hepatosplenomegaly, calcified adrenal glands, severe malabsorption and a failure to thrive...
2017: Current Chemical Genomics and Translational Medicine
https://www.readbyqxmd.com/read/28399649/perceived-discrimination-and-depressive-symptoms-among-us-latinos-the-modifying-role-of-educational-attainment
#13
Julia B Ward, Lydia Feinstein, Anissa I Vines, Whitney R Robinson, Mary N Haan, Allison E Aiello
OBJECTIVE: Despite growing evidence that discrimination may contribute to poor mental health, few studies have assessed this association among US Latinos. Furthermore, the interaction between discrimination and educational attainment in shaping Latino mental health is virtually unexplored. This study aims to examine the association between perceived discrimination and depressive symptoms and the modifying role of education among a population of Mexican-origin adults. DESIGN: We utilized population-based data from 629 Mexican-origin adults (mean age = 52...
April 12, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28384241/mental-ill-health-in-structural-pathways-to-women-s-experiences-of-intimate-partner-violence
#14
Mercilene T Machisa, Nicola Christofides, Rachel Jewkes
BACKGROUND: Depression, post-traumatic stress disorder (PTSD), and binge drinking are among mental health effects of child abuse and intimate partner violence (IPV) experiences among women. Emerging data show the potential mediating role of mental ill health in the relationship of child abuse and IPV. There is evidence that PTSD, depression and alcohol abuse are comorbid common mental disorders and that a bidirectional relationship exists between depression and IPV in some settings. Furthermore, the temporal direction in the relationship of alcohol abuse and women's IPV experiences from different studies is unclear...
2017: PloS One
https://www.readbyqxmd.com/read/28346049/adverse-childhood-experiences-among-veterinary-medical-students-a-multi-site-study
#15
Elizabeth B Strand, Jennifer Brandt, Kenita Rogers, Laurie Fonken, Ruthanne Chun, Peter Conlon, Linda Lord
This research explores Adverse Childhood Experiences (ACEs) among veterinary medical students across six academic institutions of veterinary medicine, and their relationship with depression, stress, and desire to become a veterinarian. Between April 1, 2016 and May 23, 2016, 1,118 veterinary medical students in all 4 years of the curriculum (39% response rate) completed an anonymous web-based questionnaire about ACEs, depression using the Center for Epidemiological Studies Depression scale (CESD), stress using the Perceived Stress Scale (PSS), and the age at which they wanted to become a veterinarian...
March 27, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28327387/estimation-of-the-prevalence-of-cholesteryl-ester-storage-disorder-cesd-in-a-cohort-of-patients-with-clinical-features-of-familial-hypercholesterolaemia
#16
Pauline Ashfield-Watt, Kate Haralambos, Rhiannon Edwards, Delyth Townsend, Rob Gingell, Kah Wa Li, Steve E Humphries, Ian McDowell
No abstract text is available yet for this article.
December 2016: Atherosclerosis
https://www.readbyqxmd.com/read/28322747/quantitation-of-the-rates-of-hepatic-and-intestinal-cholesterol-synthesis-in-lysosomal-acid-lipase-deficient-mice-before-and-during-treatment-with-ezetimibe
#17
COMPARATIVE STUDY
Jen-Chieh Chuang, Adam M Lopez, Stephen D Turley
Esterified cholesterol (EC) and triglycerides, contained within lipoproteins taken up by cells, are hydrolysed by lysosomal acid lipase (LAL) in the late endosomal/lysosomal (E/L) compartment. The resulting unesterified cholesterol (UC) is transported via Niemann-Pick type C2 and C1 into the cytosolic compartment where it enters a putative pool of metabolically active cholesterol that is utilized in accordance with cellular needs. Loss-of-function mutations in LIPA, the gene encoding LAL, result in dramatic increases in tissue concentrations of EC, a hallmark feature of Wolman disease and cholesteryl ester storage disease (CESD)...
July 1, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28321227/co-expression-with-the-type-3-secretion-chaperone-cest-from-enterohemorrhagic-e-coli-increases-accumulation-of-recombinant-tir-in-plant-chloroplasts
#18
Jacqueline MacDonald, Sean Miletic, Typhanie Gaildry, Adam Chin-Fatt, Rima Menassa
Type 3 secretion systems (T3SSs) are utilized by pathogenic Escherichia coli to infect their hosts and many proteins from these systems are affected by chaperones specific to T3SS-containing bacteria. Toward developing a recombinant vaccine against enterohaemorrhagic E. coli (EHEC), we expressed recombinant T3SS and related proteins from predominant EHEC serotypes in Nicotiana chloroplasts. Nicotiana benthamiana were transiently transformed to express chloroplast-targeted Tir, NleA, and EspD from the EHEC serotype O157:H7; a fusion of EspA proteins from serotypes O157:H7 and O26:H11; and a fusion of epitopes of Tir (Tir-ep) from serotypes O157:H7, O26:H11, O45:H2, and O111:H8...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28318950/cholesteryl-ester-storage-disease-an-underdiagnosed-cause-of-cirrhosis-in-adults
#19
REVIEW
Mamta Pant, Kiyoko Oshima
Cholesteryl Ester Storage Disease (CESD), is a rare multisystem autosomal recessive disorder and belongs to the broad family of lysosomal storage disorders. It can present anytime from infancy and childhood to even adulthood. The clinical manifestations are generally severe in infants and with milder forms in adults. One of the prominent sites of involvement is liver. Due to low awareness of this condition among physicians including surgical pathologists, majority of the liver biopsies, especially from the adults are often misdiagnosed as non-alcoholic fatty liver disease/non-alcoholic steatohepatitis or cryptogenic cirrhosis...
February 9, 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28220406/lysosomal-acid-lipase-deficiency-in-23-spanish-patients-high-frequency-of-the-novel-c-966-2t-g-mutation-in-wolman-disease
#20
Carla Ruiz-Andrés, Elena Sellés, Angela Arias, Laura Gort
Lysosomal acid lipase (LAL) is a lysosomal key enzyme involved in the intracellular hydrolysis of cholesteryl esters and triglycerides. Patients with very low residual LAL activity present with the infantile severe form Wolman disease (WD), while patients with some residual activity develop the less severe disorder known as Cholesteryl ester storage disorder (CESD). We present the clinical, biochemical, and molecular findings of 23 Spanish patients (22 families) with LAL deficiency. We identified eight different mutations, four of them not previously reported...
February 21, 2017: JIMD Reports
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