I V Chadaeva, S V Filonov, K A Zolotareva, B M Khandaev, N I Ershov, N L Podkolodnyy, R V Kozhemyakina, D A Rasskazov, A G Bogomolov, E Yu Kondratyuk, N V Klimova, S G Shikhevich, M A Ryazanova, L A Fedoseeva, О Е Redina, O S Kozhevnikova, N A Stefanova, N G Kolosova, A L Markel, M P Ponomarenko, D Yu Oshchepkov
The animal models used in biomedical research cover virtually every human disease. RatDEGdb, a knowledge base of the differentially expressed genes (DEGs) of the rat as a model object in biomedical research is a collection of published data on gene expression in rat strains simulating arterial hypertension, age-related diseases, psychopathological conditions and other human afflictions. The current release contains information on 25,101 DEGs representing 14,320 unique rat genes that change transcription levels in 21 tissues of 10 genetic rat strains used as models of 11 human diseases based on 45 original scientific papers...
December 2023: Vavilovskii Zhurnal Genetiki i Selektsii