Huiyao Chen, Xiang Chen, Liyuan Hu, Chang Ye, Jiantao Zhang, Guoqiang Cheng, Lin Yang, Yulan Lu, Xinran Dong, Wenhao Zhou
BACKGROUND: Acute respiratory distress syndrome (ARDS) could account for a considerable proportion of neonatal death, while the genetic etiology and pathophysiology of neonatal ARDS remain elusive. In this case-control study, 515 neonates were enrolled in the China Neonatal Genomes Project (CNGP, NCT03931707) from August 2016 to June 2021, including 196 ARDS and 319 non-ARDS matched by sex, gestational age, birth weight, perinatal asphyxia, pneumonia, sepsis, and necrotizing enterocolitis...
2022: Computational and Structural Biotechnology Journal