keyword
https://read.qxmd.com/read/38533665/introducing-the-concept-of-sanctuary-sites-in-ischemic-stroke
#1
JOURNAL ARTICLE
Tharani Thirugnanachandran, Henry Ma, Geoffrey A Donnan, David C Reutens, Thanh G Phan
BACKGROUND: The topography of arterial territories has been defined using digital maps of supratentorial infarcts. Regions with a high probability of infarction (Pi) exist in the deep compartment due to a paucity of collaterals. However, less attention has been given to regions with a low Pi. METHODS: Using published digital maps, patients with cortical stroke and documented vessel occlusion were included. Infarcts from T2 -weighted magnetic resonance images were segmented and registered onto a standard brain template (Montreal Neurological Institute 152)...
March 27, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38533146/less-is-more-a-case-report-on-all-on-4-prosthesis
#2
Dhanashree A Minase, Seema Sathe, Anjali Borle, Ankita Pathak, Tanvi Jaiswal
Severe alveolar ridge atrophy following tooth removal poses a common and worsening issue in edentulous jaws, affecting patient comfort and quality of life. The All-on-4 approach involves axially positioning two anterior implants and distally orienting two posterior implants, reducing cantilever length and enabling prostheses with 12 teeth. This less invasive option, utilizing distal tilting of implants at 30°, offers biomechanical advantages and has shown short-term success, though long-term research is limited...
February 2024: Curēus
https://read.qxmd.com/read/38521423/biosimilars-of-anti-vascular-endothelial-growth-factor-for-ophthalmic-diseases-a-review
#3
REVIEW
Neil M Bressler, Peter K Kaiser, Diana V Do, Quan Dong Nguyen, Kyu Hyung Park, Se Joon Woo, Min Sagong, Mario Bradvica, Mercy Yeeun Kim, Seungkee Kim, SriniVas R Sadda
The development of intravitreally injected biologic medicines (biologics) acting against vascular endothelial growth factor (VEGF) substantially improved the clinical outcomes of patients with common VEGF-driven retinal diseases. The relatively high cost of branded agents, however, represents a financial burden for most healthcare systems and patients, likely resulting in impaired access to treatment and poorer clinical outcomes for some patients. Biosimilar medicines (biosimilars) are clinically equivalent, potentially economic alternatives to reference products...
March 21, 2024: Survey of Ophthalmology
https://read.qxmd.com/read/38519673/what-is-occlusion-part-1
#4
JOURNAL ARTICLE
Stephen Davies
Some dentists choose to ignore the subject of occlusion, while others propose a set of doctrinal rules. It is of little wonder therefore that it can become a source of confusion and even controversy. This series of two papers aims, firstly, to answer the very simple question of 'what is occlusion?'. It will put occlusion into the context of the articulatory system because that is the bio-mechanical environment where the majority of dentists do their work. The concept of jaw relation will also be discussed but within the context of this locomotive system...
March 2024: British Dental Journal
https://read.qxmd.com/read/38514411/evaluation-of-quality-of-life-and-satisfaction-with-fixed-prostheses-on-zygomatic-implants-vs-all-on-four-concept-a-randomized-clinical-study
#5
RANDOMIZED CONTROLLED TRIAL
Mohamed A Nagib, Abdullah M Ibrahim, Fakhreldin Hassan Abdel-Rahman, Salah A Hegazy, Ahmed Habib
AIM: To compare between the rehabilitation of atrophied maxilla with fixed prosthesis using two posterior zygomatic implants and two conventional anterior implants or four implants inserted according to the all-on-four concept regarding the patient quality of life and satisfaction after one year of prosthesis insertion. MATERIALS AND METHODS: Thirty-six patients with atrophic edentulous maxillae were randomized into two groups: Group I (rehabilitated with fixed prostheses supported by two zygomatic and two conventional implants in the anterior region) and group II (fixed prostheses on four implants in the anterior region following an all-on-four concept)...
February 1, 2024: Journal of Contemporary Dental Practice
https://read.qxmd.com/read/38493898/vascular-complications-secondary-to-reboa-placement-at-a-level-1-trauma-center
#6
JOURNAL ARTICLE
Amanda Tullos, Sanjay Wunnava, Daniela Medina, Claudie Sheahan, Amit Chawla, Bruce Torrance, Amadis Brooke, Melissa Donovan, Tapash Palit, Malachi Sheahan
INTRODUCTION: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is designed to manage severe hemorrhagic shock. Popularized in medical care during military conflicts, the concept has emerged as a lifesaving technique that is utilized around the United States. Literature on risks of REBOA placement, especially vascular injuries, are not well reported. Our goal was to assess the incidence of vascular injury from REBOA placement and the risk factors associated with injury and death among these patients at our institution...
March 15, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38475189/wheat-seed-detection-and-counting-method-based-on-improved-yolov8-model
#7
JOURNAL ARTICLE
Na Ma, Yaxin Su, Lexin Yang, Zhongtao Li, Hongwen Yan
Wheat seed detection has important applications in calculating thousand-grain weight and crop breeding. In order to solve the problems of seed accumulation, adhesion, and occlusion that can lead to low counting accuracy, while ensuring fast detection speed with high accuracy, a wheat seed counting method is proposed to provide technical support for the development of the embedded platform of the seed counter. This study proposes a lightweight real-time wheat seed detection model, YOLOv8-HD, based on YOLOv8...
March 3, 2024: Sensors
https://read.qxmd.com/read/38473007/dynamic-perviousness-predicts-revascularization-success-in-acute-ischemic-stroke
#8
JOURNAL ARTICLE
Gergely Bertalan, Roxane Duparc, Miklos Krepuska, Daniel Toth, Jawid Madjidyar, Patrick Thurner, Tilman Schubert, Zsolt Kulcsar
BACKGROUND: The predictive value of thrombus perviousness in acute ischemic stroke (AIS), as measured by computed tomography (CT), has been intensively studied with conflicting results. In this study, we investigate the predictive potential of the novel concept of dynamic perviousness using three-dimensional (3D) volumetric evaluation of occlusive thrombi. METHODS: The full thrombus volume in 65 patients with a hyperdense artery sign on non-contrast CT (NCCT), who underwent mechanical thrombectomy (MT), was segmented...
March 3, 2024: Diagnostics
https://read.qxmd.com/read/38460977/predicting-parameters-of-airway-dynamics-generated-from-inspiratory-and-expiratory-plethysmographic-airway-loops-differentiating-subtypes-of-chronic-obstructive-diseases
#9
JOURNAL ARTICLE
Richard Kraemer, Hans-Jürgen Smith, Juergen Reinstaedtler, Sabina Gallati, Heinrich Matthys
BACKGROUND: The plethysmographic shift volume-flow loop (sRaw -loop) measured during tidal breathing allows the determination of several lung function parameters such as the effective specific airway resistance (sReff ), calculated from the ratio of the integral of the resistive aerodynamic specific work of breathing (sWOB) and the integral of the corresponding flow-volume loop. However, computing the inspiratory and expiratory areas of the sRaw -loop separately permits the determination of further parameters of airway dynamics...
March 9, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38448977/torso-hemorrhage-noncompressible-never-say-never
#10
REVIEW
Lian-Yang Zhang, Hua-Yu Zhang
Since limb bleeding has been well managed by extremity tourniquets, the management of exsanguinating torso hemorrhage (TH) has become a hot issue both in military and civilian medicine. Conventional hemostatic techniques are ineffective for managing traumatic bleeding of organs and vessels within the torso due to the anatomical features. The designation of noncompressible torso hemorrhage (NCTH) marks a significant step in investigating the injury mechanisms and developing effective methods for bleeding control...
March 6, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38366215/long-term-occlusal-tooth-wear-at-the-onset-of-permanent-dentition
#11
JOURNAL ARTICLE
Thomas Schmid, Konstantinos Dritsas, Meret Gebistorf, Demetrios Halazonetis, Christos Katsaros, Nikolaos Gkantidis
OBJECTIVES: This study quantified the long-term occlusal wear in the natural posterior teeth and the associations per tooth type within the dentition. METHODS: The sample included 70 orthodontically treated subjects (52 females and 18 males; median age, 14.3 years), followed for a 12.7-year period. They were consecutively selected with no tooth wear-related criteria. Post-treatment (T1) and follow-up dental casts (T2) were scanned and superimposed through three-dimensional methods...
February 16, 2024: Clinical Oral Investigations
https://read.qxmd.com/read/38363252/sleep-bruxism-the-past-the-present-and-the-future-evolution-of-a-concept
#12
REVIEW
Davis C Thomas, Daniele Manfredini, Jaimin Patel, Aaron George, Bindu Chanamolu, Priyanka Kodaganallur Pitchumani, Linda Sangalli
BACKGROUND: The concept of sleep bruxism (SB) has evolved exponentially over the past several decades. Many theories and hypotheses have been proposed as to the definition, pathophysiology, and management of SB, from the early 1960s through the present. The role of peripheral factors, such as dental occlusion, in the pathogenesis of SB has been discarded. TYPES OF STUDIES REVIEWED: The authors searched several electronic databases (ie, PubMed, Google Scholar, Web of Science, Embase, and Ovid MEDLINE) for studies on bruxism...
February 16, 2024: Journal of the American Dental Association
https://read.qxmd.com/read/38362005/management-of-non-compressible-torso-hemorrhage-of-the-abdomen-in-civilian-and-military-austere-environments-a-scoping-review
#13
REVIEW
Donald Adams, Paige L McDonald, Seth Holland, Alexander B Merkle, Christen Puglia, Becky Miller, Deidre D Allison, Christina Moussette, Christopher J Souza, Timothy Nunez, Philip van der Wees
BACKGROUND: Non-compressible abdominal hemorrhage (NCAH) is the leading cause of potentially preventable deaths in both civilian and military austere environments, and an improvement in mortality due to this problem has not been demonstrated during the past quarter century. Several innovations have been developed to control hemorrhage closer to the point of injury. OBJECTIVE: This review assessed NCAH interventions in civilian and military settings, focusing on austere environments...
2024: Trauma Surgery & Acute Care Open
https://read.qxmd.com/read/38350299/luminal-delivery-of-pectin-modified-oxygen-microbubbles-mitigates-rodent-experimental-intestinal-ischemia
#14
JOURNAL ARTICLE
Mathew Morreau, Ernest Cheah, Sachin Thakur, Jiwon Hong, Anthony Hickey, Anthony Phillips, John Windsor
INTRODUCTION: Ischemic gut injury is common in the intensive care unit, impairs gut barrier function, and contributes to multiorgan dysfunction. One novel intervention to mitigate ischemic gut injury is the direct luminal delivery of oxygen microbubbles (OMB). Formulations of OMB can be modified to control the rate of oxygen delivery. This project examined whether luminal delivery of pectin-modified OMB (OMBp5) can reduce ischemic gut injury in a rodent model. METHODS: The OMBp5 formulation was adapted to improve delivery of oxygen along the length of small intestine...
February 12, 2024: Journal of Surgical Research
https://read.qxmd.com/read/38332406/a-proof-of-concept-optimized-jawbone-reduction-model-for-mandibular-fracture-surgery
#15
JOURNAL ARTICLE
Jinmin Kim, Deokgi Jeung, Ranyeong Cho, Byoungeun Yang, Jaesung Hong
Previous research on computer-assisted jawbone reduction for mandibular fracture surgery has only focused on the relationship between fractured sections disregarding proper dental occlusion with the maxilla. To overcome malocclusion caused by overlooking dental articulation, this study aims to provide a model for jawbone reduction based on dental occlusion. After dental landmarks and fracture sectional features are extracted, the maxilla and two mandible segments are aligned first using the extracted dental landmarks...
February 8, 2024: J Imaging Inform Med
https://read.qxmd.com/read/38284945/myocentric-relation-in-an-additive-esthetic-rehabilitation-within-a-fully-digital-workflow
#16
JOURNAL ARTICLE
Joris Delavy, Cristina Lopez, Leonardo Franchini, Giovanni Tommaso Rocca, Carlo Massimo Saratti
In recent years, tooth wear has been a growing concern in dentistry as it has become increasingly prevalent among the population. At the same time, the development of adhesive techniques has enabled minimally invasive treatment protocols, with the goal of preserving and protecting teeth for as long as possible. This clinical report presents the case of a full-mouth rehabilitation patient with tooth wear who was treated using minimally invasive techniques. Esthetic and functional outcomes were designed and monitored using digital tools such as digital impressions, 3D facial scans, a digital tooth library, transcutaneous electrical nerve stimulation (TENS), MRI, and kinesiographic (KS) analysis throughout the treatment...
January 29, 2024: International Journal of Esthetic Dentistry
https://read.qxmd.com/read/38280254/adversarial-learning-based-domain-adaptation-algorithm-for-intracranial-artery-stenosis-detection-on-multi-source-datasets
#17
JOURNAL ARTICLE
Yuan Gao, Chenbin Ma, Lishuang Guo, Guiyou Liu, Xuxiang Zhang, Xunming Ji
Intracranial arterial stenosis (ICAS) is characterized by the pathological narrowing or occlusion of the inner lumen of intracranial blood vessels. However, the retina can indirectly react to cerebrovascular disease. Therefore, retinal fundus images (RFI) serve as valuable noninvasive and easily accessible screening tools for early detection and diagnosis of ICAS. This paper introduces an adversarial learning-based domain adaptation algorithm (ALDA) specifically designed for ICAS detection in multi-source datasets...
January 21, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38277910/a-parametrical-finite-element-analysis-for-functionally-graded-material-overlay-restoration
#18
JOURNAL ARTICLE
Vincent Fouquet, Nicoline Larsen, Anne-Constance Stchepinsky, Elsa Vennat, Aurélie Benoit, Laurent Tapie
The main cause of failure in bonded ceramic restorations is material fracture due to excessive stress concentration at the base of the prosthesis. The design of restorative functionally graded materials (FGM) could represent a major advance in dissipating mechanical stresses during occlusal contacts. The aim of this paper is to carry out a complete factorial design of finite element analyses to optimize a multilayer FGM introduced at the bottom of an overlay prosthesis. The number and thickness of layers vary within a spectrum compatible with ceramic shaping processes whereas Young's moduli variations are set in the range of dental tissues...
January 17, 2024: Journal of the Mechanical Behavior of Biomedical Materials
https://read.qxmd.com/read/38272761/a-combined-3d-printed-metal-and-resin-digital-denture-5-year-follow-up-data-and-a-creative-design-concept
#19
JOURNAL ARTICLE
Seungyong Park, Chan Park
Many denture frameworks are currently manufactured using metal 3-dimensional (3D) printing technology. However, this advanced technology is still limited to conventional denture designs. A metal 3D printing-based denture design concept was developed and is presented based on a nonwear occlusal surface, a nonfracture denture base, and a novel connection between metal and resin.
January 24, 2024: Journal of Prosthetic Dentistry
https://read.qxmd.com/read/38263141/identifying-barriers-and-strategies-for-achieving-competency-in-removable-prosthodontics-in-undergraduate-dental-students-a-mixed-method-study
#20
JOURNAL ARTICLE
Watcharapong Mongkolrattanasit, Veerit Tanvarasethee, Kittapob Thangjantaraprapab, Supachai Chuenjitwongsa, Nareudee Limpuangthip
BACKGROUND: Developing competency in removable prosthodontics (RP) is challenging for undergraduate dental students because it involves threshold concepts and tacit knowledge. Understanding this process can enhance learning and professional development in RP. The objective of this study was to identify the barriers hindering knowledge (threshold concept) and skill (tacit knowledge) development, and to propose strategies for achieving RP competency. METHODS: Adopting critical theory, quantitative and qualitative approaches were implemented...
January 23, 2024: BMC Oral Health
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