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https://www.readbyqxmd.com/read/29456102/the-prognostic-capacity-of-transvaginal-hydrolaparoscopy-to-predict-non-ivf-conception
#1
Mianne van Kessel, Rachel Tros, Jur Oosterhuis, Walter H Kuchenbecker, Elly M Vernooij, Marlies Y Bongers, Ben Willem J Mol, Carolien A Koks
Transvaginal hydrolaparoscopy (THL) is performed to investigate tubal pathology in subfertile women. This retrospective multicentre cohort study investigated the results of THL and subsequent pregnancy rates. Between 2000 and 2011, 1033 subfertile women participated in the study. The primary outcome measure was intrauterine pregnancy, either after natural conception or after treatment with intrauterine insemination or ovulation induction. Cumulative intrauterine pregnancy rates were calculated using Kaplan-Meier analysis and fecundity rate ratios (FRR) were established...
February 5, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29452273/3d-bioprinted-functional-and-contractile-cardiac-tissue-constructs
#2
Zhan Wang, Sang Jin Lee, Heng-Jie Cheng, James J Yoo, Anthony Atala
Bioengineering of a functional cardiac tissue composed of primary cardiomyocytes has great potential for myocardial regeneration and in vitro tissue modeling. However, its applications remain limited because the cardiac tissue is a highly organized structure with unique physiologic, biomechanical, and electrical properties. In this study, we undertook a proof-of-concept study to develop a contractile cardiac tissue with cellular organization, uniformity, and scalability by using three-dimensional (3D) bioprinting strategy...
February 13, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29447311/a-simplified-approach-for-restoration-of-worn-dentition-using-the-full-mock-up-concept-clinical-case-reports
#3
Stefen Koubi, Galip Gurel, Patrice Margossian, Richard Massihi, Herve Tassery
Treatment of tooth wear has increased over the last two decades. However, the treatments involved have not been satisfactory to most patients, nor have they achieved the expected goal on some worn teeth. New approaches have emerged to reconstruct full arches in a minimally invasive way that take advantage of developments in the field of adhesive dentistry. These new concepts constitute a revolution in dentistry and their application requires adapted techniques and training. The purpose of this article is to suggest a precise and reproducible method that simplifies the treatment of worn dentition...
March 2018: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/29431849/medical-treatment-in-the-management-of-deep-endometriosis-infiltrating-the-proximal-rectum-and-sigmoid-colon-a-comprehensive-literature-review
#4
Paolo Vercellini, Laura Buggio, Alessandra Borghi, Ermelinda Monti, Umberto Gattei, Maria Pina Frattaruolo
A comprehensive literature review was performed to evaluate the effect of various hormonal therapies, in terms of variations of intestinal and pain complaints and of patient satisfaction with treatment, in women with symptomatic, non-severely sub-occlusive endometriosis infiltrating the proximal rectum and sigmoid colon. A MEDLINE search through PubMed from 2000 to 2018 was conducted to identify all original English language articles published on medical treatment for colorectal endometriosis. Additional reports were identified by systematically reviewing reference lists and using the "similar articles" function in PubMed...
February 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29408767/the-woven-endobridge-web-for-endovascular-therapy-of-intracranial-aneurysms-update-of-a-systematic-review-with-meta-analysis
#5
Noam Tau, Udi Sadeh-Gonik, Gilles Aulagner, Francis Turjman, Benjamin Gory, Xavier Armoiry
OBJECTIVES: Endovascular treatment of wide-neck intracranial aneurysms (IAs) is challenging, especially in bifurcation location. The intra-saccular flow-disruptor Woven EndoBridge (WEB) offers a new concept of endovascular therapy for wide-neck IAs. We performed an update of a systematic review aimed to report the feasibility, effectiveness and safety of WEB device therapy. PATIENTS AND METHODS: A systematic review was conducted using several electronic databases (including PUBMED and EMBASE), searching for studies published between October 2015 and December 2017 (those published between January 2010 and September 2015 were included in our initial systematic review)...
January 31, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29398312/implementation-of-a-virtual-vascular-clinic-with-point-of-care-ultrasound-in-an-integrated-health-care-system
#6
Judith C Lin, Janelle M Crutchfield, Dana K Zurawski, Courtney Stevens
OBJECTIVE: Using secured videoconferencing technologies, telemedicine may replace traditional clinic visits, save patients' time and travel, and improve use of limited surgeon and facility resources. We report our initial experience of the remote clinical encounter (RCE) by evaluating vascular surgery patients. METHODS: In this proof-of-concept pilot study, we conducted telemedicine evaluations of vascular patients at a tertiary care institution from October 2015 to August 2016...
February 1, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29395454/outcomes-of-treatment-for-intracapsular-fractures-of-the-mandibular-condyle-recommendation-for-a-new-classification
#7
B B Ying, Q Q Zhang, S S Zhu, Y F Li
We know of no universally accepted classification for intracapsular condylar fractures. We propose here a new classification based on the concept of a "disc-condyle" unit, and validate the classification based on outcomes of treatment. From 1 January 2010 - 31 December 2014, 55 patients with unilateral intracapsular condylar fractures were classified into three types: type A has no reduction in mandibular height or displacement of the disc (n=7); type B has displacement of the disc with no reduction in mandibular height (n=17); and type C has reduced mandibular height with or without displacement of the disc (n=31)...
February 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29371173/temporary-simultaneous-two-arterial-occlusions-testo-during-laparoscopic-management-for-cornual-ectopic-pregnancy
#8
Haeree Yang, Taejong Song
STUDY OBJECTIVE: To demonstrate a new technique of TEmporary Simultaneous Two-arterial Occlusions (TESTO) of uterine and ovarian (or utero-ovarian) artery to reduce operative blood loss during laparoscopic cornual resection for cornual ectopic pregnancy. DESIGN: A step-by-step explanation of the surgical procedure using video (Canadian Task Force classification III). This study was approved by the Institutional Review Board. SETTING: A university hospital PATIENTS: A 41-year-old woman presented with pelvic pain with 7 weeks of amenorrhea...
January 22, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29343482/par1-biased-signaling-is-required-for-activated-protein-c-in-vivo-benefits-in-sepsis-and-stroke
#9
Ranjeet K Sinha, Yaoming Wang, Zhen Zhao, Xiao Xu, Laurent Burnier, Naveen Gupta, José A Fernandez, Greg Martin, Sergey Kupriyanov, Laurent O Mosnier, Berislav V Zlokovic, John H Griffin
Activated Protein C (APC) cleaves protease activated receptor (PAR)1 in vitro at R46 to initiate beneficial cell signaling; however, thrombin and APC can cleave at R41. To elucidate PAR1-dependent aspects of pharmacologic APC's in vivo mechanisms, we generated C57BL/6 mouse strains carrying QQ41 or QQ46 point mutations in PAR1 ( F2r gene). Using these strains, we determined whether or not recombinant murine signaling-selective APC mutants would reduce septic death or provide neuroprotection against ischemic stroke when mice carried PAR1 homozygous mutations that prevent cleavage at either R41 or R46...
January 17, 2018: Blood
https://www.readbyqxmd.com/read/29316570/the-randomized-shortened-dental-arch-study-tooth-loss-over-10-years
#10
Michael H Walter, Jens Dreyhaupt, Wolfgang Hannak, Stefan Wolfart, Ralph G Luthardt, Helmut Stark, Peter Pospiech, Torsten Mundt, Matthias Kern, Klaus Walter Böning, Bernd Wöstmann, Herbert Scheller, Florentine Jahn, Wilfried Reinhardt, Joerg Strub, Birgit Marré, Guido Heydecke
PURPOSE: This study aimed to compare the long-term outcomes of two different nonimplant treatments in the bilateral shortened dental arch (SDA). MATERIALS AND METHODS: In a multicenter randomized controlled clinical trial, patients with complete molar loss in one arch were assigned to one of two different nonimplant treatments. In the partial removable dental prosthesis (PRDP) group, patients were provided with a distal-extension prosthesis retained with precision attachments...
January 2018: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/29251013/ultrastructure-of-neurovascular-changes-in-human-diabetic-retinopathy
#11
János Fehér, Samanta Taurone, Marialuisa Spoletini, Zsolt Biró, Balázs Varsányi, Gianluca Scuderi, Maria Patrizia Orlando, Rosaria Turchetta, Alessandra Micera, Marco Artico
The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation. The aim of this study was to reveal the potential role of neuronal and glial cells in initial and advanced alterations of the retinopathy in human type 2 diabetes. Electron microscopy and histochemical studies were performed on 38 surgically removed human eyes (28 obtained from diabetic patients and 10 from non-diabetic patients)...
December 1, 2017: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/29243415/compact-dual-mode-diffuse-optical-system-for-blood-perfusion-monitoring-in-a-porcine-model-of-microvascular-tissue-flaps
#12
Seung Yup Lee, Julia M Pakela, Michael C Helton, Karthik Vishwanath, Yooree G Chung, Noah J Kolodziejski, Christopher J Stapels, Daniel R McAdams, Daniel E Fernandez, James F Christian, Jameson O'Reilly, Dana Farkas, Brent B Ward, Stephen E Feinberg, Mary-Ann Mycek
In reconstructive surgery, the ability to detect blood flow interruptions to grafted tissue represents a critical step in preventing postsurgical complications. We have developed and pilot tested a compact, fiber-based device that combines two complimentary modalities-diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy-to quantitatively monitor blood perfusion. We present a proof-of-concept study on an in vivo porcine model (n=8). With a controllable arterial blood flow supply, occlusion studies (n=4) were performed on surgically isolated free flaps while the device simultaneously monitored blood flow through the supplying artery as well as flap perfusion from three orientations: the distal side of the flap and two transdermal channels...
December 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29241221/diagnosis-risk-assessment-and-treatment-decisions-for-occlusal-caries-a-survey-from-the-danish-public-dental-health-service
#13
Joana Christina Carvalho, Vibeke Qvist, Nicole R Aimée, Heliana D Mestrinho, Azam Bakhshandeh
This study validates a case-based survey method and analyzes the extent to which Danish dental professionals apply current concepts and strategies for occlusal caries management in children, adolescents, and young adults. A case-based, precoded questionnaire consisting of 10 clinical cases/patients with 26 teeth/occlusal surfaces was developed. The cases were set up in a PowerPoint presentation and color printed as a booklet illustrating patients with different patterns of caries activity, severity, and risk...
December 15, 2017: Caries Research
https://www.readbyqxmd.com/read/29239104/the-development-of-nonanatomic-denture-occlusion-part-i
#14
Robert L Engelmeier
Part I of this two-part article concentrates on the early 20th century origin of the nonanatomic concept of complete denture occlusion. It focuses on Dr. Victor Sears, who in 1922 made a courageous departure from convention when he introduced the design for his "Chewing Members." Development of these teeth marked the birth of the School of Nonanatomic Denture Occlusion. Dr. Sears' 35-year journey of research and development is traced here through his mid-1950s association with Dr. Simon Myerson. Their Myerson-Sears design set the standard for flat-planed, nonanatomic denture teeth for the next half century...
December 14, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29222244/cardiovascular-care-of-patients-with-chronic-myeloid-leukemia-cml-on-tyrosine-kinase-inhibitor-tki-therapy
#15
REVIEW
Mary C Barber, Michael J Mauro, Javid Moslehi
Cardiovascular (CV) health has emerged as an important consideration in patients with chronic myeloid leukemia (CML) because of improved prognosis. Indeed, the success of BCR-ABL1 tyrosine kinase inhibitors (TKIs) has increased the focus on survivorship and late toxicity in oncological care. Survivorship issues in this population include CV disease prevention, given its prevalence in the general population. The introduction of BCR-ABL1 TKIs represented a unique concept of indefinite cancer therapy, only recently evolving to include "treatment-free remission...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29220863/a-small-dose-of-apomorphine-counteracts-the-deleterious-effects-of-middle-cerebral-artery-occlusion-in-different-models
#16
F Mastroiacovo, A Gaglione, C L Busceti, L Ryskalin, G Bozza, F Nicoletti, F Orzi, F Fornai
The present manuscript investigates in two animal species by using two different experimental models of middle cerebral artery occlusion (permanent and transient), the neuroprotective effects of the dopamine receptor agonist apomorphine. These effects were evaluated by measuring the infarct volume and by counting muscle strength at different time points following the ischemic insult. Apomorphine at the dose of 3 mg/Kg when adminsitered at two hours following the occlusion of the middle cerebral artery was able to reduce significantly the infarct volume in the cortex of mice and the ischemic volume of the basal ganglia perfused by the perforant branches of the middle cerebral artery in the rat...
September 1, 2017: Archives Italiennes de Biologie
https://www.readbyqxmd.com/read/29201488/left-brachiocephalic-vein-stenosis-due-to-the-insertion-of-a-temporal-right-subclavian-hemodialysis-catheter
#17
Eleni I Skandalou, Fani D Apostolidou-Kiouti, Ilias D Minasidis, Ioannis K Skandalos
Central vein stenosis/occlusion is a common well-described sequel to the placement of hemodialysis catheters in the central venous system. The precise mechanisms by which central vein stenosis occurs are not well known. Current concepts in central vein stenosis pathophysiology focus on the response to vessel injury model, emphasizing the process of trauma. A case of left brachiocephalic vein stenosis due to the insertion and function of a temporary right subclavian hemodialysis catheter is presented. The purpose of the manuscript is to emphasize that, with the introduction of a temporary subclavian hemodialysis catheter via the right subclavian vein apart from causing concurrent stenosis/infarction of the right subclavian and right brachiocephalic vein, it is also possible to cause stenosis of the left brachiocephalic vein (close to its contribution to the superior vena cava) although the catheter tip is placed in the correct anatomical position in the superior vena cava...
2017: Case Reports in Vascular Medicine
https://www.readbyqxmd.com/read/29198948/multivariate-prognostic-model-of-acute-stroke-combining-admission-infarct-location-and-symptom-severity-a-proof-of-concept-study
#18
Seyedmehdi Payabvash, John C Benson, Andrew E Tyan, Shayandokht Taleb, Alexander M McKinney
BACKGROUND: The information on topographic distribution of acute ischemic infarct can contribute to prediction of functional outcome. We aimed to develop a multivariate model for stroke prognostication, combining admission clinical and imaging variables, including the infarct topology. METHODS: Acute ischemic stroke patients without baseline functional disability who had magnetic resonance imaging within 24 hours of onset or last-seen-well were included. The admission stroke severity was determined using the National Institutes of Health Stroke Scale (NIHSS) score...
November 29, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29186595/treatment-of-recurrent-intracranial-aneurysms-after-neck-clipping-novel-classification-scheme-and-management-strategies
#19
Shinya Kobayashi, Junta Moroi, Kentaro Hikichi, Shotaro Yoshioka, Hiroshi Saito, Jun Tanabe, Tatsuya Ishikawa
BACKGROUND: Recurrent aneurysms after initial clipping have been discussed as an important issue in the surgical management of aneurysm. OBJECTIVE: To report our experience with recurrent cerebral aneurysms after neck clipping and to discuss classification and recommended management. METHODS: Aneurysm treatments from a single institution over a 20-year period were retrospectively reviewed. Twenty-three recurrent aneurysms in 23 patients were managed during the study period...
December 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29159684/early-experience-with-a-new-concept-of-angioplasty-nitinol-constrained-balloon-catheter-chocolate-%C3%A2-in-severely-claudicant-patients
#20
Pasqualino Sirignano, Wassim Mansour, Alessandro d'Adamo, Simone Cuozzo, Laura Capoccia, Francesco Speziale
BACKGROUND: To report our experience in treating severely claudicant patients, employing a "nitinol-constrained" balloon (Chocolate, TriReme Medical Inc., Pleasanton, CA-USA) before drug-coated balloon (DCB) in a standardized protocol. METHODS: Eighty-one (84 limbs) consecutive Rutherford category (RC) 3 patients treated between December 2014 and December 2016 for superficial femoral artery (SFA) and popliteal arterial (PA) disease by nitinol-constrained balloon followed by DCB were enrolled...
November 20, 2017: Cardiovascular and Interventional Radiology
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