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https://www.readbyqxmd.com/read/28728975/continuous-nitrogen-removal-by-a-single-stage-reactor-packed-with-ring-laced-string-medium
#1
Masahiro Tatara, Shu Ishikawa, Yoshiyuki Ueno
The efficiency of nitrogen removal by a partial-nitritation/anammox (PNA) reaction was investigated using a packed-bed reactor in which ring-laced strings were used as the supporting medium. A stable population of PNA microorganisms was established from typical activated sludge, after less than two months of acclimation in the packed-bed reactor, by applying a high nitrogen-loading rate (NLR: 0.53 kg/m(3)/d) and short hydraulic retention time (HRT: 1.8 h). The stability of reactor performance was confirmed in industrial wastewater (IW), demonstrating a nitrogen removal efficiency (NRE) of greater than 77% during 260 days of continuous operation, between 0...
July 17, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28728415/-177-lu-labelled-cyclic-minigastrin-analogues-with-therapeutic-activity-in-cck2r-expressing-tumours-preclinical-evaluation-of-a-kit-formulation
#2
Christine Rangger, Maximilian Klingler, Lajos Balogh, Zita Pöstényi, Andras Polyak, Dariusz Pawlak, Renata Mikołajczak, Elisabeth von Guggenberg
Minigastrin (MG) analogues specifically target cholecystokinin-2 receptors (CCK2R) expressed in different tumours and enable targeted radiotherapy of advanced and disseminated disease when radiolabelled with a beta emitter such as (177)Lu. Especially truncated MG analogues missing the penta-Glu sequence are associated with low kidney retention and seem therefore most promising for therapeutic use. Based on [D-Glu1,desGlu2-6]MG (MG11) we have designed the two cyclic MG analogues cyclo1,9[γ-D-Glu1,desGlu2-6,D-Lys9]MG (cyclo-MG1) and cyclo1,9[γ-D-Glu1,desGlu2-6,D-Lys9,Nle11]MG (cyclo-MG2)...
July 20, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28700791/efficacy-of-tramadol-extended-release-for-opioid-withdrawal-a-randomized-clinical-trial
#3
Kelly E Dunn, D Andrew Tompkins, George E Bigelow, Eric C Strain
Importance: Opioid use disorder (OUD) is a significant public health problem. Supervised withdrawal (ie, detoxification) from opioids using clonidine or buprenorphine hydrochloride is a widely used treatment. Objective: To evaluate whether tramadol hydrochloride extended-release (ER), an approved analgesic with opioid and nonopioid mechanisms of action and low abuse potential, is effective for use in supervised withdrawal settings. Design, Setting, and Participants: A randomized clinical trial was conducted in a residential research setting with 103 participants with OUD...
July 12, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28693573/a-qualitative-assessment-of-an-abstinence-oriented-therapeutic-community-for-prisoners-with-substance-use-disorders-in-kyrgyzstan
#4
Lyuba Azbel, Julia Rozanova, Ingo Michels, Frederick L Altice, Heino Stöver
BACKGROUND: Kyrgyzstan, where HIV is concentrated in prisons and driven by injection drug use, provides a prison-based methadone maintenance therapy program as well as abstinence-oriented therapeutic community based on the 12-step model called the "Clean Zone." We aimed to qualitatively assess how prisoners navigate between these treatment options to understand the persistence of the Clean Zone despite a lack of evidence to support its effectiveness in treating opioid use disorders. METHODS: We conducted an analysis of policy documents and over 60 h of participant observation in February 2016, which included focus groups with a convenience sample of 20 therapeutic community staff members, 110 prisoners across three male and one female prisons, and qualitative interviews with two former Clean Zone participants...
July 10, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28661126/transition-metal-ions-enable-the-transition-from-electrospun-prolamin-protein-fibers-to-nitrogen-doped-freestanding-carbon-films-for-flexible-supercapacitors
#5
Yixiang Wang, Jingqi Yang, Rongbing Du, Lingyun Chen
Flexible carbon ultrafine fibers are highly desirable in energy storage and conversion devices. Our previous finding showed that electrospun hordein/zein fibers stabilized by Ca(2+) were successfully transferred into nitrogen-doped carbon ultrafine fibers for supercapacitors. However, their relatively brittle nature needed to be improved. Inspired by this stabilizing effect of Ca(2+), in this work, four transition metal divalent cations were used to assist the formation of flexible hordein/zein-derived carbon ultrafine fibers...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28628356/clips-versus-resilient-liners-used-with-bilateral-posterior-prefabricated-bars-for-retaining-four-implant-supported-mandibular-overdentures
#6
Mona Gibreel, Mohammed Fouad, Fatma El-Waseef, Nesma El-Amier, Hamdy Marzook
The objective of this research was to clinically compare peri-implant tissue health of bar-clips versus silicone-resilient liners used with bilateral posterior bars for retaining four implant supported mandibular overdentures. Thirty completely edentulous male patients (mean age 65) were randomly assigned into two equal groups. Each patient received four implants in canine and first molar regions of the mandible using flapless surgical technique. Mandibular overdentures were immediately connected to the implants with bilateral prefabricated instant adjusting bars...
June 19, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28619721/hagfish-slime-exudate-stabilization-and-its-effect-on-slime-formation-and-functionality
#7
L J Böni, R Zurflüh, M Widmer, P Fischer, E J Windhab, P A Rühs, S Kuster
Hagfish produce vast amounts of slime when under attack. The slime is the most dilute hydrogel known to date, and is a highly interesting material for biomaterial research. It forms from a glandular secrete, called exudate, which deploys upon contact with seawater. To study slime formation ex vivo and to characterize its material properties, stabilization of the sensitive slime exudate is crucial. In this study, we compared the two main stabilization methods, dispersion in high osmolarity citrate/PIPES (CP) buffer and immersion in oil, and tested the influence of time, temperature and pH on the stability of the exudate and functionality of the slime...
July 15, 2017: Biology Open
https://www.readbyqxmd.com/read/28589922/graphene-oxide-hydrogel-as-a-restricted-area-nanoreactor-for-synthesis-of-3d-graphene-supported-ultrafine-tio2-nanorod-nanocomposites-for-high-rate-lithium-ion-battery-anodes
#8
Jianli Cheng, Guifang Gu, Wei Ni, Qun Guan, Yinchuan Li, Bin Wang
Three-dimensional graphene-supported TiO2 nanorod nanocomposites (3D GS-TNR) are prepared using graphene oxide hydrogel as a restricted-area nanoreactor in the hydrothermal process, in which well-distributed TiO2 nanorods with a width of approximately 5 nm and length of 30 nm are conformally embedded in the 3D interconnected graphene network. The 3D graphene oxide not only works as a restricted-area nanoreactor to constrain the size, distribution and morphology of the TiO2; it also work as a highly interconnected conducting network to facilitate electrochemical reactions and maintain good structural integration when the nanocomposites are used as anode materials in lithium-ion batteries...
June 7, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28571293/management-of-severely-atrophic-mandibular-ridge-using-hollow-denture-with-an-analytical-discussion-a-clinical-case-report
#9
Rupal Jaydip Shah, Sanjay Balaji Lagdive, Satyaprakash Ranjit Shah, Vishal Bipinbihari Verma, Shraddha Lalit Saini
A severely resorbed edentulous mandibular ridge, although fairly common in occurrence, its rehabilitation poses a challenging clinical situation for the prosthodontist. This has implored prosthodontists to seek for ingenious modifications in the conventional prosthetic forms so as to gratify patient's expectations who have difficulty in wearing the mandibular complete dentures. Opting for the most suitable treatment modality mandates equilibrating the retention, stability and support triad to the fullest. Extreme resorption of the denture bearing tissue bed may lead to problems with achieving adequate levels of prosthetic satisfaction for the patient...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28535354/high-capacity-and-ultrafast-na-ion-storage-of-a-self-supported-3d-porous-antimony-persulfide-graphene-foam-architecture
#10
Yanying Lu, Ning Zhang, Shuang Jiang, Yudong Zhang, Meng Zhou, Zhanliang Tao, Lynden A Archer, Jun Chen
The key challenge for high-performance sodium-ion batteries is the exploitation of appropriate electrode materials with a long cycling stability and high rate capability. Here, we report Sb2S5 nanoparticles (∼5 nm) uniformly encapsulated in three-dimensional (3D) porous graphene foam, which were fabricated by a facile hydrothermal coassembly strategy, as a high-performance anode material for sodium-ion batteries. The as-prepared composite can be directly used as electrodes without adding a binder or current collector, exhibiting outstanding electrochemical performance with a high reversible capacity (845 mA h g(-1) at 0...
June 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28533736/telescopic-overdenture-a-case-report
#11
C S Shruthi, R Poojya, Swati Ram, Anupama
PATIENT: This report describes the case of a 68 year old female patient who presented with the chief complaint of difficulty in chewing and poor aesthetics due to missing teeth. The patient was interested in saving the remaining natural teeth and desired minimal tissue coverage from the prosthesis. After consideration of all the factors involved, it was deemed advisable to resort to a palate free maxillary telescopic complete denture and a mandibular removable partial denture. DISCUSSION: Considering the age of the patient and the cost involved, implant supported prosthesis was ruled out as a treatment option for the patient...
March 2017: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28494331/graduate-nurses-evaluation-of-mentorship-development-of-a-new-tool
#12
Lay Hwa Tiew, Catherine S L Koh, Debra K Creedy, W S W Tam
AIM: Develop and test an instrument to measure graduate-nurses' perceptions of a structured mentorship program. BACKGROUND: New graduate nurses may experience difficulties in the transition from student to practitioner. Mentoring is commonly used to support graduates. However, there is a lack of published tools measuring graduate nurses' perceptions of mentorship. As mentoring is resource intensive, development and testing of a validated tool are important to assist in determining program effectiveness...
July 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28487369/n-glycosylation-affects-the-stability-and-barrier-function-of-the-muc16-mucin
#13
Takazumi Taniguchi, Ashley M Woodward, Paula Magnelli, Nicole M McColgan, Sylvain Lehoux, Sarah Melissa P Jacobo, Jérôme Mauris, Pablo Argüeso
Transmembrane mucins are highly O-glycosylated glycoproteins that coat the apical glycocalyx on mucosal surfaces and represent the first line of cellular defense against infection and injury. Relatively low levels of N-glycans are found on transmembrane mucins, and their structure and function remain poorly characterized. We previously reported that carbohydrate-dependent interactions of transmembrane mucins with galectin-3 contribute to maintenance of the epithelial barrier at the ocular surface. Now, using MALDI-TOF mass spectrometry, we report that transmembrane mucin N-glycans in differentiated human corneal epithelial cells contain primarily complex-type structures with N-acetyllactosamine, a preferred galectin ligand...
June 30, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28469829/combination-prosthetic-design-providing-a-superior-retention-for-mid-facial-defect-rehabilitation-a-case-report
#14
Supassra Nilanonth, Prana Shakya, Natdhanai Chotprasert, Theerathavaj Srithavaj
Large maxillofacial defects from malignant tumor treatment are rarely rehabilitated by surgical reconstruction alone. Ameloblastic carcinoma, a rare aggressive odontogenic malignant tumor, requires wide surgical excision to gain a tumor-free margin. In the post-surgical defect, prosthetic rehabilitation is the treatment of choice to restore function and esthetics. Moreover, an intra-oral prosthesis such as an obturator restores speech, mastication and deglutition. Retention of the obturator is a major problem while rehabilitating large defects...
April 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28447378/soil-aggregation-and-associated-microbial-communities-modify-the-impact-of-agricultural-management-on-carbon-content
#15
Pankaj Trivedi, Manuel Delgado-Baquerizo, Thomas C Jeffries, Chanda Trivedi, Ian C Anderson, Matthew McNee, Kenneth Flower, Bhupinder Pal Singh, David Minkey, Brajesh K Singh
Soil carbon (C) stabilization is known to depend in part on its distribution in structural aggregates, and upon soil microbial activity within the aggregates. However, the mechanisms and relative contributions of different microbial groups to C turnover in different aggregates under various management practices remain unclear. The aim of this study was to determine the role of soil aggregation and their associated microbial communities in driving the responses of soil organic matter (SOM) to multiple management practices...
April 26, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28391850/increasing-the-efficiency-of-immobilization-and-chitin-determination-using-copper-oxide-nanoparticles
#16
Preety, Vinita Hooda
A novel polyurethane (PU) support with and without copper oxide nanoparticles (nCuO) was employed for immobilization of two chitinolytic enzymes, chitinase and N-acetyl β glucosaminidase (NAGase) to yield PU/nCuO/chitinase/NAGase and PU/chitinase/NAGase conjugates respectively. The surface morphologies, topologies and bonded interactions between different components of the immobilized enzyme conjugates were characterized using Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM) and Fourier Transform Infrared Spectroscopy (FTIR) respectively...
June 1, 2017: Talanta
https://www.readbyqxmd.com/read/28383131/the-hollow-maxillary-complete-denture-a-simple-precise-single-flask-technique-using-a-caramel-spacer
#17
Prem Bhushan, Meena A Aras, Vidya Chitre, Ashwin R Mysore, Kennedy Mascarenhas, Swati Kumar
The success of removable prostheses ultimately depends on a number of factors such as retention, stability, support, esthetics, and masticatory function. Increased intraoral inter-arch distance leads to an increase in the weight of the prosthesis. This may compromise the retention and resistance, which are key for a successful removable prosthesis. Various methods, techniques, and materials have been reported to minimize the weight of a prosthesis. This article describes a simple, unique, precise single-flask technique for the fabrication of a lightweight maxillary prosthesis using caramel as a 3D spacer, which was "indexed" to obtain a uniform thickness of acrylic around the hollow cavity...
April 6, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28378928/azagly-appended-peptidomimetics-structurally-related-to-ptr6154-as-potential-pkb-akt-inhibitors
#18
Shalini Singh, Richa Shrivastava, Gajendra Singh, Rafat Ali, Ravi Sankar Ampapathi, Smrati Bhadhuria, Wahajul Haq
We report the synthesis and biological and physiochemical properties of a series of azaGly-appended peptidomimetics. We have developed a simple and facile synthesis for azapeptides on solid support without any side reaction. The azaGly is inserted by in situ reaction of disuccinimidyl carbonate with free amine followed by treatment of hydrazine hydrate at room temperature. The new series of peptidomimetics was prepared by azaGly scanning of heptapeptide Arg-Pro-Arg-Nle-Tyr-Dap-Nle (Akt-01), a GSK-3β-derived Akt inhibitor...
June 19, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28375862/clinical-evaluation-of-implant-supported-removable-partial-dentures-with-a-stress-breaking-attachment
#19
Yasunori Suzuki, Kentaro Kono, Hidemasa Shimpo, Yohei Sato, Chikahiro Ohkubo
PURPOSE: The stress-breaking ball (SBB) attachment can distribute the occlusal force equally between the alveolar ridge and the implants. The purpose of this study was to evaluate the implant-supported distal extension removable partial dentures (RPDs) with SBB attachment in 10 patients who were partially edentulous. METHODS: This randomized crossover study was designed to compare the function of RPDs with and without healing abutments and SBB attachments to support the posterior aspects of the RPDs...
August 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28368615/role-of-cell-appendages-in-initial-attachment-and-stability-of-e-coli-on-silica-monitored-by-nondestructive-tirf-microscopy
#20
Kerwin K W Wong, Adam L J Olsson, Bahareh Asadishad, Bart van der Bruggen, Nathalie Tufenkji
Total internal reflection fluorescence (TIRF) microscopy was used to investigate initial attachment and stability of wild-type, curli-deficient (ΔcsgA), flagella-deficient (ΔflhDC), and type-1 fimbriae-deficient (Δfim) mutant E. coli strains. Suspended bacteria were injected into a flow cell where they deposited on a silica coverslip, and images were acquired over a 2 min period. TIRF microscope image analysis revealed that curli- and flagella-deficient mutants attached closer to the surface and required a longer time to find their equilibrium position (i...
April 11, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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