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https://www.readbyqxmd.com/read/28391850/increasing-the-efficiency-of-immobilization-and-chitin-determination-using-copper-oxide-nanoparticles
#1
Preety, Vinita Hooda
A novel polyurethane (PU) support with and without copper oxide nanoparticles (nCuO) was employed for immobilization of two chitinolytic enzymes, chitinase and N-acetyl β glucosaminidase (NAGase) to yield PU/nCuO/chitinase/NAGase and PU/chitinase/NAGase conjugates respectively. The surface morphologies, topologies and bonded interactions between different components of the immobilized enzyme conjugates were characterized using Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM) and Fourier Transform Infrared Spectroscopy (FTIR) respectively...
June 1, 2017: Talanta
https://www.readbyqxmd.com/read/28383131/the-hollow-maxillary-complete-denture-a-simple-precise-single-flask-technique-using-a-caramel-spacer
#2
Prem Bhushan, Meena A Aras, Vidya Chitre, Ashwin R Mysore, Kennedy Mascarenhas, Swati Kumar
The success of removable prostheses ultimately depends on a number of factors such as retention, stability, support, esthetics, and masticatory function. Increased intraoral inter-arch distance leads to an increase in the weight of the prosthesis. This may compromise the retention and resistance, which are key for a successful removable prosthesis. Various methods, techniques, and materials have been reported to minimize the weight of a prosthesis. This article describes a simple, unique, precise single-flask technique for the fabrication of a lightweight maxillary prosthesis using caramel as a 3D spacer, which was "indexed" to obtain a uniform thickness of acrylic around the hollow cavity...
April 6, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28378928/azagly-appended-peptidomimetics-structurally-related-to-ptr6154-as-potential-pkb-akt-inhibitors
#3
Shalini Singh, Richa Shrivastava, Gajendra Singh, Rafat Ali, Smrati Bhadhuria, Ravi Sankar Ampapathi, W Haq
Herein we report synthesis, biological and physiochemical properties of a new series of azaGly appended peptides peptidomimetics. We have developed a simple and facile synthesis of azapeptides on solid support without any side reaction. The azaGly inserted by in-situ reaction of disuccinimidyl carbonate with free amine followed by treatment of hydrazine hydrate at room temperature. The new series of peptidomimetics was prepared by azaGly scan of hepta-peptide, Arg-Pro-Arg-Nle-Tyr-Dap-Nle (Akt-01), a GSK3β derived Akt-inhibitor...
April 5, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28375862/clinical-evaluation-of-implant-supported-removable-partial-dentures-with-a-stress-breaking-attachment
#4
Yasunori Suzuki, Kentaro Kono, Hidemasa Shimpo, Yohei Sato, Chikahiro Ohkubo
PURPOSE: The stress-breaking ball (SBB) attachment can distribute the occlusal force equally between the alveolar ridge and the implants. The purpose of this study was to evaluate the implant-supported distal extension removable partial dentures (RPDs) with SBB attachment in 10 patients who were partially edentulous. METHODS: This randomized crossover study was designed to compare the function of RPDs with and without healing abutments and SBB attachments to support the posterior aspects of the RPDs...
April 3, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28368615/role-of-cell-appendages-in-initial-attachment-and-stability-of-e-coli-on-silica-monitored-by-non-destructive-tirf-microscopy
#5
Kerwin K W Wong, Adam L J Olsson, Bahareh Asadishad, Bart van der Bruggen, Nathalie Tufenkji
Total internal reflection fluorescence (TIRF) microscopy was used to investigate initial attachment and stability of wild-type, curli-deficient (ΔcsgA), flagella-deficient (ΔflhDC) and type-1 fimbriae-deficient (Δfim) mutant E. coli strains. Suspended bacteria were injected into a flow cell where they deposited on a silica cover slip and images were acquired over a 2 minute period. TIRF microscope image analysis revealed that curli- and flagella-deficient mutants attached closer to the surface and required a longer time to find their equilibrium position (i...
April 3, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28363649/immobilization-of-euphorbia-tirucalli-peroxidase-onto-chitosan-cobalt-oxide-magnetic-nanoparticles-and-optimization-using-response-surface-methodology
#6
Ankita Shukla, Ravi Kumar Gundampati, Medicherla V Jagannadham
Euphorbia tirucalli peroxidase (ETP) was immobilized on chitosan beads having magnetic properties for the ease of separation and increasing the reusability of ETP for cost effective assay conditions. The present work reports immobilization of ETP on polymeric support chitosan-cobalt oxide beads subsequently activated with 0.05% cynuric chloride. The magnetic immobilized enzyme was characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) analysis and scanning electron microscopy (SEM)...
March 29, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28335023/qbd-driven-development-and-validation-of-liquid-chromatography-tandem-mass-spectrometric-method-for-the-quantitation-of-sildenafil-in-human-plasma
#7
M Saquib Hasnain, Shaukat Ali Ansari, Shireen Rao, Mohammad Tabish, Mukul Singh, Mohammad Syafiq Abdullah, Mohammed Tahir Ansari
The present work was employing the Quality by Design approach for the development and validation of a LC-MS-MS method to support the clinical advancement in determination of sildenafil in human plasma using lorazepam as an internal standard. Sample preparation involved solid phase extraction and calibration range observed between 3 and 1,700 ng/mL. The method was systematically optimized by employing Box-Behnken design and used mobile phase flow rate, pH and composition of mobile phase as the critical factors, and assessing the design for retention time and peak area as the responses...
February 27, 2017: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/28324627/hospitalized-opioid-dependent-patients-exploring-predictors-of-buprenorphine-treatment-entry-and-retention-after-discharge
#8
Christina S Lee, Jane M Liebschutz, Bradley J Anderson, Michael D Stein
OBJECTIVES: Few studies have explored predictors of entry into and retention in buprenorphine treatment following linkage from an acute medical hospitalization. METHODS: This secondary analysis of a completed clinical trial focuses on medically hospitalized, opioid-dependent patients (n = 72) who were randomized to an intervention including buprenorphine induction and dose stabilization during hospitalization followed by post-discharge transition to office-based buprenorphine treatment (OBOT)...
March 21, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28295611/variation-in-networks-and-forms-of-support-for-care-seeking-across-the-hiv-care-continuum-in-the-rural-southeastern-united-states
#9
Miranda Hill, Amber Huff, Neale Chumbler
PURPOSE: In spite of progress in understanding the importance of social support for health outcomes in Persons Living with HIV (PLWH), more remains to be known about mechanisms of support most beneficial at each stage of HIV treatment. In this study, we use a qualitative analytic approach to investigate the forms and sources of social support deemed most integral to the diagnosis, care engagement, and medication adherence behaviors of a diverse sample of PLWH in a mostly rural health district in the Southeastern United States...
March 14, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28263587/rapid-achievement-of-nitritation-using-aerobic-starvation
#10
Wenlong Liu, Qing Yang, Bin Ma, Jun Li, Linna Ma, Shuying Wang, Yongzhen Peng
Rapid start-up of partial nitrification is of great significance for subsequent denitrification and the anammox process; however, slow nitritation hinders the application of these processes. The current study presents a novel strategy for achieving nitritation using aerobic starvation and controlling sludge retention time (SRT). Activated sludge with a high level of complete nitrification was introduced into an aerated reactor without feeding to start the aerobic starvation. The results showed that nitritation was rapidly achieved, while the shorter SRT (15 days) guaranteed the stability of nitritation with an average nitrite accumulation ratio (NAR) of more than 95%...
March 16, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28262903/an-efficient-route-to-fabricate-fatigue-free-p-vdf-trfe-capacitors-with-enhanced-piezoelectric-and-ferroelectric-properties-and-excellent-thermal-stability-for-sensing-and-memory-applications
#11
Deepa Singh, Deepak, Ashish Garg
P(VDF-TrFE), the best known ferroelectric polymer, suffers from a rather low piezoelectric response as well as poor electrical fatigue life, hampering its application potential. Herein, we report the fabrication of fatigue free poly(vinylidenedifluoride-trifluoroethylene) P(VDF-TrFE)-based capacitors with record piezoelectric coefficients and excellent thermal stability. We proposed a cost-effective and simple solution-based process to fabricate P(VDF-TrFE)-based memory capacitors with large polarization (8...
March 6, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28218617/chimeric-protein-repair-of-laminin-polymerization-ameliorates-muscular-dystrophy-phenotype
#12
Karen K McKee, Stephanie C Crosson, Sarina Meinen, Judith R Reinhard, Markus A Rüegg, Peter D Yurchenco
Mutations in laminin α2-subunit (Lmα2, encoded by LAMA2) are linked to approximately 30% of congenital muscular dystrophy cases. Mice with a homozygous mutation in Lama2 (dy2J mice) express a nonpolymerizing form of laminin-211 (Lm211) and are a model for ambulatory-type Lmα2-deficient muscular dystrophy. Here, we developed transgenic dy2J mice with muscle-specific expression of αLNNd, a laminin/nidogen chimeric protein that provides a missing polymerization domain. Muscle-specific expression of αLNNd in dy2J mice resulted in strong amelioration of the dystrophic phenotype, manifested by the prevention of fibrosis and restoration of forelimb grip strength...
March 1, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28206804/student-service-members-veterans-on-campus-challenges-for-reintegration
#13
Brian Borsari, Ali Yurasek, Mary Beth Miller, James G Murphy, Meghan E McDevitt-Murphy, Matthew P Martens, Monica G Darcy, Kate B Carey
Many returning OIF/OEF/OND Veterans are seeking higher education in an effort to develop a meaningful career and financial stability. Evidence suggests that student service members/veterans (SSM/Vs) are experiencing less academic success than other students. The purpose of this review is to identify the unique challenges of SSM/Vs and evaluate current campus efforts to facilitate their retention and academic performance. With a focus on SSM/Vs attending colleges and universities, we obtained 57 peer-reviewed and 73 gray literature records published between 2001 and 2015...
2017: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/28170246/chemical-stabilization-of-unnatural-nucleotide-triphosphates-for-the-in-vivo-expansion-of-the-genetic-alphabet
#14
Aaron W Feldman, Vivian T Dien, Floyd E Romesberg
We have developed an unnatural base pair (UBP) and a semisynthetic organism (SSO) that imports the constituent unnatural nucleoside triphosphates and uses them to replicate DNA containing the UBP. However, propagation of the UBP is at least in part limited by the stability of the unnatural triphosphates, which are degraded by cellular and secreted phosphatases. To circumvent this problem, we now report the synthesis and evaluation of unnatural triphosphates with their β,γ-bridging oxygen replaced with a difluoromethylene moiety, yielding dNaMTP(CF2) and dTPT3TP(CF2)...
February 15, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28163363/female-perception-of-a-partner-s-mate-value-discrepancy-and-controlling-behaviour-in-romantic-relationships
#15
Dariusz P Danel, Agnieszka Siennicka, Kinga Glińska, Piotr Fedurek, Natalia Nowak-Szczepańska, Ewa A Jankowska, Bogusław Pawłowski, Zdzisław Lewandowski
Mate value discrepancy (MVD) between heterosexual partners is an important factor influencing relationship satisfaction which, in turn, has an effect on the quality and the stability of the relationship. Therefore, partners' involvement in mate retention behaviours, such as controlling behaviours, can be related to MVD and our study aims to determine whether such an association exists. In order to do so, we analysed female perception of MVD and their opinion regarding the intensity of controlling behaviours performed by themselves as well as their romantic partners...
2017: Acta Ethologica
https://www.readbyqxmd.com/read/28128494/retention-of-the-zn-zn-bond-in-ge9-zn-znge9-6-and-formation-of-ge9-zn-ge9-znge9-8-and-polymeric-1%C3%A2-ge9-zn-2-1
#16
Kerstin Mayer, Laura-Alice Jantke, Stephan Schulz, Thomas F Fässler
Reactions of Zn(I)2 L2 (where L=[HC(PPh2 NPh)](-) ) with solutions of the Zintl phase K4 Ge9 in liquid ammonia lead to retention of the Zn-Zn bond and formation of the anion [(η(4) -Ge9 )Zn-Zn(η(4) -Ge9 )](6-) , representing the first complex with a Zn-Zn unit carrying two cluster entities. The trimeric anion [(η(4) -Ge9 )Zn{μ2 (η(1) :η(1) Ge9 )}Zn(η(4) -Ge9 )](8-) forms as a side product, indicating that oxidation reactions also take place. The reaction of Zn2 Cp*2 (Cp*=1,2,3,4,5-pentamethylcyclopentadienyl) with K4 Ge9 in ethylenediamine yielded the linear polymeric unit 1∞ {[Zn[μ2 (η(4) :η(1) Ge9 )]}(2-) with the first head-to-tail arrangement of ten-atom closo-clusters...
January 27, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28079645/the-role-of-patient-navigators-in-building-a-medical-home-for-multiply-diagnosed-hiv-positive-homeless-populations
#17
Mariana Sarango, Alexander de Groot, Melissa Hirschi, Chukwuemeka Anthony Umeh, Serena Rajabiun
CONTEXT: People living with human immunodeficiency virus (HIV) (PLWH) who are most at risk for falling out of HIV primary care and detectable viral loads include homeless and unstably housed individuals and those codiagnosed with behavioral health disorders. The patient-centered medical home (PCMH) is a model that promotes provision of comprehensive, patient-centered, accessible, coordinated, and quality care for patients. This initiative provided patient navigation to HIV-positive homeless and unstably housed individuals codiagnosed with a mental health or substance use disorder as a means to create an adapted PCMH to meet the specific needs of this population...
May 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28067457/oxide-nanotrap-anchored-platinum-nanoparticles-with-high-activity-and-sintering-resistance-by-area-selective-atomic-layer-deposition
#18
Xiao Liu, Qianqian Zhu, Yun Lang, Kun Cao, Shengqi Chu, Bin Shan, Rong Chen
An area-selective atomic layer deposition (AS-ALD) method is described to construct oxide nanotraps to anchor Pt nanoparticles (NPs) on Al2 O3 supports. The as-synthesized catalysts have exhibited outstanding room-temperature CO oxidation activity, with a significantly lowered apparent activation energy (ca. 22.17 kJ mol(-1) ) that is half that of pure Pt catalyst with the same loading. Furthermore, the structure shows excellent sintering resistance with the high catalytic activity retention up to 600 °C calcination...
January 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28050985/patients-awareness-toward-implant-supported-prosthesis-an-observational-study
#19
C Mahendra Raju, Sumanth Gunupati, Madisetty Mahesh Babu, C Sameer Kumar Reddy, Sukrutha Biradavolu, M Saravanan
INTRODUCTION: Implant-supported prosthesis has high predictability and success and improves quality of life. This study aims at assessing awareness among the patients regarding implant-supported prosthesis. MATERIALS AND METHODS: A cross-sectional study was conducted among 391 study participants. A structured questionnaire was distributed to assess implant-related awareness among the study participants. The questionnaires were analyzed for the responses. RESULTS: Among the 391 respondents, 37...
January 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28042277/distal-extension-mandibular-removable-partial-denture-with-implant-support
#20
Canan Bural, Begum Buzbas, Sebnem Ozatik, Gulsen Bayraktar, Yusuf Emes
This case report describes the fabrication of a distal extension removable partial denture (RPD) of a 65-year-old man with implant support. Loss of fibroelasticity of the peripheral tissues and reduced mandibular vestibular sulcular depth due to a previous surgical resection and radiotherapy at the right side were the main clinical factors that created difficulty for denture retention and stability. The fabrication of a mandibular RPD supported by anterior teeth and two bilaterally placed implants in the molar area to convert from Kennedy Class 1 design to Kennedy Class 3 implant-bounded RPD is reported...
October 2016: European Journal of Dentistry
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