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https://www.readbyqxmd.com/read/29149878/assessing-the-delivery-of-alcohol-screening-and-brief-intervention-in-sexual-health-clinics-in-the-north-east-of-england
#1
C Sullivan, N Martin, C White, D Newbury-Birch
BACKGROUND: Risky drinking is associated with risky sexual experiences, however the relationship between alcohol and sex is complex. The aim of the study was to assess the feasibility of delivering alcohol screening and brief interventions in genitourinary medicine (GUM) clinics. The objectives were to; understand the levels of alcohol use amongst patients; report on the number of alcohol interventions delivered; and to analyse the relationship between alcohol use with demographic data as well as diagnosed sexually transmitted infections (STIs) to see if there were any associations...
November 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29148839/sexual-risk-behaviors-and-perceptions-of-men-who-go-to-gay-sex-parties-in-new-york-city-comparisons-between-three-hiv-groups
#2
Étienne Meunier, Karolynn Siegel
Men who have sex with men (MSM) who attend group-sex events often engage in risky sexual behaviors that contribute to the high human immunodeficiency virus (HIV) incidence among this population. We conducted an online survey with 211 New York City MSM who attended sex parties in the prior year and asked them to describe their behaviors and perceptions of risk. We compared responses from HIV-positive-undetectable men (n = 36), HIV-negative men on pre-exposure prophylaxis (PrEP; n = 62), and HIV-negative men never on PrEP (n = 113)...
November 17, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29140439/bivalent-vaccine-effectiveness-against-type-specific-hpv-positivity-evidence-for-cross-protection-against-oncogenic-types-among-dutch-sti-clinic-visitors
#3
Petra J Woestenberg, Audrey J King, Birgit H B van Benthem, Robine Donken, Suzan Leussink, Fiona R M van der Klis, Hester E de Melker, Marianne A B van der Sande, Christian J P A Hoebe, Johannes A Bogaards
Background: Observational post-marketing studies are important to assess vaccine effectiveness (VE). We estimated VE from the bivalent human papillomavirus (HPV) vaccine against HPV positivity of vaccine and non-vaccine types in a high-risk population. Methods: We included all vaccine-eligible women from the PASSYON study, a biennial cross-sectional survey in Dutch sexually transmitted infection clinics. Vaginal swabs were analyzed using a PCR-based assay (SPF10-LiPA25) able to detect the 12 high-risk HPV (hrHPV) types 16/18/31/33/35/39/45/51/52/56/58/59...
November 11, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29132501/low-education-levels-are-associated-with-early-age-of-sexual-debut-drug-use-and-risky-sexual-behaviours-among-young-indigenous-australians
#4
Handan Wand, Joanne Bryant, Heather Worth, Marian Pitts, John M Kaldor, Dea Delaney-Thiele, James Ward
Background: Earlier age at sexual debut is associated with drug and alcohol use, risky sexual behaviours and sexually transmissible infections (STI). Methods: In the present study, 2320 young Indigenous Australians were surveyed. Results: Most study participants had sex for the first time when they were 14 years or younger (79% and 67% for males and females respectively). More than 80% of participants were categorised as being in the high-risk category for the combined sexual risk factors (i.e. not using condoms, drunk or high at last sexual act, or three or more sexual partners in the past year)...
November 14, 2017: Sexual Health
https://www.readbyqxmd.com/read/29130407/hiv-and-other-stis-in-male-sex-workers-findings-from-a-sexual-health-promotion-intervention-in-vietnam
#5
Lloyd A Goldsamt, Michael C Clatts, Le Minh Giang, Bao Q Le, Donn J Colby, Gary Yu
Male sex workers (MSWs) in Vietnam are at high risk for acquisition and transmission of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs), yet are extremely disengaged from the healthcare system. This contributes to large numbers of untreated or late-treated infections and increased secondary transmission. We enrolled 995 MSWs in Hanoi and Ho Chi Minh City (HCMC) in a Sexual Health Promotion intervention that included face-to-face delivery of seven content modules, a clinical examination and testing for HIV, syphilis, gonorrhea and Chlamydia...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29128125/-diagnostic-issues-of-lymphogranuloma-venereum-a-case-series-of-5%C3%A2-patients
#6
A Fabre-Baudouin, A L Roux, C Marin, M Lachatre, M De Laroche, M Ponsoye, T Hanslik, S Trad
INTRODUCTION: Lymphogranuloma venereum (LG) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis L serovar. METHODS: These five consecutive cases aim to highlight the risk of LG misdiagnosis, in case of initial presentation with isolated inguinal adenitis. RESULTS: Five men (mean age: 30±7 years) were seen in an internal medicine department, for inguinal adenopathy. One patient had clinical signs of urethritis. None presented an associated rectitis...
November 8, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29128033/association-of-the-emergency-medical-services-related-time-interval-with-survival-outcomes-of-out-of-hospital-cardiac-arrest-cases-in-four-asian-metropolitan-cities-using-the-scoop-and-run-emergency-medical-services-model
#7
Tae Han Kim, Kyungwon Lee, Sang Do Shin, Young Sun Ro, Hideharu Tanaka, Susan Yap, Kwanhathai Darin Wong, Yih Yng Ng, Thammapad Piyasuwankul, Benjamin Leong
BACKGROUND: Response time interval (RTI) and scene time interval (STI) are key time variables in the out-of-hospital cardiac arrest (OHCA) cases treated and transported via emergency medical services (EMS). OBJECTIVE: We evaluated distribution and interactive association of RTI and STI with survival outcomes of OHCA in four Asian metropolitan cities. METHODS: An OHCA cohort from Pan-Asian Resuscitation Outcome Study (PAROS) conducted between January 2009 and December 2011 was analyzed...
November 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29124421/if-you-film-it-will-they-watch-factors-associated-with-willingness-to-view-safer-sex-messaging-in-internet-based-sexually-explicit-media
#8
Martin J Downing, Nadav Antebi-Gruszka, Eric W Schrimshaw, Sabina Hirshfield
Research on the association between viewing condomless sex in sexually explicit media (SEM) and engaging in risk behavior suggests the need for SEM-based safer sex messaging (e.g., PrEP, condom use), though few studies have considered viewer willingness to watch SEM containing HIV/STI prevention messages. Online survey data from a racially diverse sample of 859 men and women were used to investigate factors associated with willingness to watch SEM with safer sex messaging. Analyses were conducted separately for three groups: heterosexual men and other men who only report sex with women, heterosexual women and other women who only report sex with men, and gay, bisexual, and other men who have sex with men...
November 9, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29120699/tolerability-response-and-outcome-of-high-risk-neuroblastoma-patients-treated-with-long-term-infusion-of-anti-gd2-antibody-ch14-18-cho
#9
Ina Mueller, Karoline Ehlert, Stefanie Endres, Lena Pill, Nikolai Siebert, Silke Kietz, Penelope Brock, Alberto Garaventa, Dominique Valteau-Couanet, Evelyne Janzek, Norbert Hosten, Andreas Zinke, Winfried Barthlen, Emine Varol, Hans Loibner, Ruth Ladenstein, Holger N Lode
Immunotherapy with short term infusion (STI) of monoclonal anti-GD2 antibody (mAb) ch14.18 (4 × 25mg/m(2)/d; 8-20h) in combination with cytokines and 13-cis retinoic acid (RA) prolonged survival in high-risk neuroblastoma (NB) patients. Here, we investigated long-term infusion (LTI) of ch14.18 produced in Chinese hamster ovary cells (ch14.18/CHO; 10 × 10mg/m(2); 24h) in combination with subcutaneous (s.c.) interleukin-2 (IL-2) in a single center program and report clinical response, toxicity and survival...
November 9, 2017: MAbs
https://www.readbyqxmd.com/read/29113967/clinical-characteristics-of-children-presenting-with-a-suspicion-or-allegation-of-historic-sexual-abuse
#10
Sarah Al-Jilaihawi, Kevin Borg, Katharine Jamieson, Sabine Maguire, Deborah Hodes
INTRODUCTION: Police-recorded sexual offences against children and young people (CYP) increased 85% in the UK between 2010/2011 and 2014/2015. Many children delay disclosure, but little data are available regarding characteristics of CYP presenting with historic child sexual abuse (CSA). AIM: To identify the clinical and CSA-related characteristics of CYP presenting with a suspicion or allegation of historic CSA. METHOD: Data were collected on all CYP<17 years presenting with suspected or alleged historic CSA (ie, >3 days since last sexual assault in prepubertal children, >7 days pubertal girls) between October 2009 and November 2014...
November 7, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29112736/varcards-an-integrated-genetic-and-clinical-database-for-coding-variants-in-the-human-genome
#11
Jinchen Li, Leisheng Shi, Kun Zhang, Yi Zhang, Shanshan Hu, Tingting Zhao, Huajing Teng, Xianfeng Li, Yi Jiang, Liying Ji, Zhongsheng Sun
A growing number of genomic tools and databases were developed to facilitate the interpretation of genomic variants, particularly in coding regions. However, these tools are separately available in different online websites or databases, making it challenging for general clinicians, geneticists and biologists to obtain the first-hand information regarding some particular variants and genes of interest. Starting with coding regions and splice sties, we artificially generated all possible single nucleotide variants (n = 110 154 363) and cataloged all reported insertion and deletions (n = 1 223 370)...
November 3, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29111911/trends-in-long-acting-reversible-contraceptive-larc-use-larc-use-predictors-and-dual-method-use-among-a-national-sample-of-college-women
#12
Eric R Walsh-Buhi, Hannah L Helmy
OBJECTIVE: Assess long-acting reversible contraceptive (LARC) and other contraceptive use trends, identify LARC use predictors, and examine dual method use. PARTICIPANTS: Females in the American College Health Association-National College Health Assessment (ACHA-NCHA) II, aged 18-24 years, who reported having vaginal sex (N = 37,899). METHODS: Secondary analyses of Fall 2011-2014 ACHA-NCHA II data. RESULTS: Statistically significant increases in LARC usage and, specifically, implant usage, were found...
November 7, 2017: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29110216/punto-seguro-a-randomized-controlled-pilot-using-conditional-economic-incentives-to-reduce-sexually-transmitted-infection-risks-in-mexico
#13
Omar Galárraga, Sandra G Sosa-Rubí, Caroline Kuo, Pedro Gozalo, Andrea González, Biani Saavedra, Nathalie Gras-Allain, Carlos J Conde-Glez, Maria Olamendi-Portugal, Kenneth H Mayer, Don Operario
Randomized controlled pilot evaluated effect of conditional economic incentives (CEIs) on number of sex partners, condom use, and incident sexually transmitted infections (STIs) among male sex workers in Mexico City. Incentives were contingent on testing free of new curable STIs and/or clinic attendance. We assessed outcomes for n = 227 participants at 6 and 12 months (during active phase with incentives), and then at 18 months (with incentives removed). We used intention-to-treat and inverse probability weighting for the analysis...
November 7, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29104824/comparative-genomic-analysis-of-the-pks-genes-in-five-species-and-expression-analysis-in-upland-cotton
#14
Xueqiang Su, Xu Sun, Xi Cheng, Yanan Wang, Muhammad Abdullah, Manli Li, Dahui Li, Junshan Gao, Yongping Cai, Yi Lin
Plant type III polyketide synthase (PKS) can catalyse the formation of a series of secondary metabolites with different structures and different biological functions; the enzyme plays an important role in plant growth, development and resistance to stress. At present, the PKS gene has been identified and studied in a variety of plants. Here, we identified 11 PKS genes from upland cotton (Gossypium hirsutum) and compared them with 41 PKS genes in Populus tremula, Vitis vinifera, Malus domestica and Arabidopsis thaliana...
2017: PeerJ
https://www.readbyqxmd.com/read/29101138/do-digital-innovations-for-hiv-and-sexually-transmitted-infections-work-results-from-a-systematic-review-1996-2017
#15
Jana Daher, Rohit Vijh, Blake Linthwaite, Sailly Dave, John Kim, Keertan Dheda, Trevor Peter, Nitika Pant Pai
OBJECTIVE: Digital innovations with internet/mobile phones offer a potential cost-saving solution for overburdened health systems with high service delivery costs to improve efficiency of HIV/STI (sexually transmitted infections) control initiatives. However, their overall evidence has not yet been appraised. We evaluated the feasibility and impact of all digital innovations for all HIV/STIs. DESIGN: Systematic review. SETTING/PARTICIPANTS: All settings/all participants...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29100520/the-emergence-of-ethical-issues-in-the-provision-of-online-sexual-health-outreach-for-gay-bisexual-two-spirit-and-other-men-who-have-sex-with-men-perspectives-of-online-outreach-workers
#16
Sophia Fantus, Rusty Souleymanov, Nathan J Lachowsky, David J Brennan
BACKGROUND: Mobile applications and socio-sexual networking websites are used by outreach workers to respond synchronously to questions and provide information, resources, and referrals on sexual health and STI/HIV prevention, testing, and care to gay, bisexual and other men who have sex with men (GB2M). This exploratory study examined ethical issues identified by online outreach workers who conduct online sexual health outreach for GB2M. METHODS: Semi-structured individual interviews were conducted between November 2013 and April 2014 with online providers and managers (n = 22) to explore the benefits, challenges, and ethical implications of delivering online outreach services in Ontario, Canada...
November 3, 2017: BMC Medical Ethics
https://www.readbyqxmd.com/read/29098498/racial-residential-segregation-and-sti-diagnosis-among-non-hispanic-blacks-2006-2010
#17
Khaleeq Lutfi, Mary Jo Trepka, Kristopher P Fennie, Gladys Ibañez, Hugh Gladwin
Sexually transmitted infections (STI) disproportionately impact non-Hispanic blacks. Racial residential segregation has been associated with negative socioeconomic outcomes. We sought to examine the association between segregation and STI diagnosis among blacks. The National Survey of Family Growth and US Census served as data sources. Five distinct dimensions represent segregation. The association between STI diagnosis and each segregation dimension was assessed with multilevel logistic regression modeling...
November 2, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29097418/prevalence-and-treatment-outcomes-of-routine-chlamydia-trachomatis-neisseria-gonorrhoeae-and-trichomonas-vaginalis-testing-during-antenatal-care-gaborone-botswana
#18
Adriane Wynn, Doreen Ramogola-Masire, Ponatshego Gaolebale, Neo Moshashane, Ontiretse Sickboy, Sofia Duque, Elizabeth Williams, Klara Doherty, Jeffrey D Klausner, Chelsea Morroni
OBJECTIVES: Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Trichomonas vaginalis (TV) are curable, mostly asymptomatic, STIs that cause adverse maternal and perinatal outcomes. Most countries do not test for those infections during antenatal care. We implemented a CT, NG and TV testing and treatment programme in an antenatal clinic in Gaborone, Botswana. METHODS: We conducted a prospective study in the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana...
November 2, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29095843/transgender-female-sex-workers-hiv-knowledge-experienced-stigma-and-condom-use-in-the-dominican-republic
#19
Henna Budhwani, Kristine R Hearld, Julia Hasbun, Rebecca Charow, Santo Rosario, Louise Tillotson, Elaine McGlaughlin, John Waters
INTRODUCTION: Not only do transgender female sex workers have some of the highest rates of sexually transmitted infections (STI), human immunodeficiency virus (HIV), and experienced stigma, they also have higher likelihood of early sexual debut and some of the lowest levels of educational attainment compared to other stigmatized populations. Some of the most common interventions designed to reduce transmission of HIV and STIs seek to educate high-risk groups on sexual health and encourage condom use across all partner types; however, reaching stigmatized populations, particularly those in resource-limited settings, is particularly challenging...
2017: PloS One
https://www.readbyqxmd.com/read/29093234/comparative-cost-analysis-of-four-interventions-to-prevent-hiv-transmission-in-bandung-indonesia
#20
Eveline J M Verstraaten, Fenna M M Beeren, Jip L C Janssen, Sophie Kemper, Adiatma Y M Siregar, Noor Tromp, Rob Baltussen
BACKGROUND: the costs of HIV/AIDS interventions in Indonesia are largely unknown. Knowing these costs is an important input for policy makers in the decision-making of setting priorities among HIV/AIDS interventions. The aim of this analysis is to determine the costs of four HIV/AIDS interventions in Bandung, Indonesia in 2015, to inform the local AIDS commission. METHODS: data on utilization and costs of the different interventions were collected in a sexual transmitted infections (STI)-clinic and the KPA, the local HIV/AIDS commission, for the period of January 2015-December 2015...
July 2017: Acta Medica Indonesiana
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