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https://www.readbyqxmd.com/read/28088256/ethnobotanics-used-in-folk-medicine-of-tamil-culture-in-sri-lanka-a-scientific-review
#1
REVIEW
Anternite Shanthi Jesuthasan, Deepthi Inoka Uluwaduge
Tamil culture has recognized the potential use of plant herbs for prevention and treatment of different diseases. These folk remedies have been practiced by Sri Lankan Tamils even after modernization. This review focuses on frequently used medicinal plants among Sri Lankan Tamil communities, such as Cuminum cyminum, Azadirechta indica, Coriandrum sativum, Sesamum indicum, Zingiber officinale, Trigonella foenum-graecum, Moringa oleifera, Plectranthus amboinicus, Allium sativum and Curcuma longa, for their documented medicinal properties, which include antimicrobial, antioxidant, antitumor, anti-inflammatory, antihypertensive, hypocholesterolemic, antidiabetic and diuretic effects...
January 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28065501/synthesis-docking-cytotoxicity-and-lta4h-inhibitory-activity-of-new-gingerol-derivatives-as-potential-colorectal-cancer-therapy
#2
Mai H El-Naggar, Amira Mira, Fatma M Abdel Bar, Kuniyoshi Shimizu, Mohamed M Amer, Farid A Badria
Leukotriene A4 hydrolase (LTA4H) is a proinflammatory enzyme that generates the inflammatory mediator leukotriene which may play an important role in chronic inflammation associated carcinogenesis. [6]-gingerol, the major bioactive compound of Zingiber officinale, is a potential inhibitor of LTA4H, a highly expressed enzyme in colorectal carcinoma. Eighteen compounds; seven of natural origin (including [4]-, [6]-, [8]-, and [10]-gingerol), five new and six known semi-synthesized [6]-gingerol derivatives were examined using docking, in vitro cytotoxicity against human colon cancer cells (HCT-116) and LTA4H aminopeptidase and epoxide hydrolase inhibitory studies...
December 29, 2016: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28053576/in-vitro-effectiveness-of-curcuma-longa-and-zingiber-officinale-extracts-on-echinococcus-protoscoleces
#3
Esam Almalki, Esam M Al-Shaebi, Saleh Al-Quarishy, Mansour El-Matbouli, Abdel-Azeem S Abdel-Baki
Hydatid disease is an important economic and human public health problem with a wide geographical distribution. Surgical excision remains the primary treatment and the only hope for complete cure of hydatosis. The most important complications arising from surgical excision, however, is recurrence, which is due to dissemination of protoscolices during the surgery. Pre-surgical inactivation of the contents of the hydatid cyst by injection of scolicidal agent into the cyst has been used as adjunct to surgery in order to overcome the risk of recurrence...
January 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28049462/new-herbal-composition-oa-f2-protects-cartilage-degeneration-in-a-rat-model-of-collagenase-induced-osteoarthritis
#4
Pallavi S Nirmal, Suresh D Jagtap, Aarti N Narkhede, Bhagyashri E Nagarkar, Abhay M Harsulkar
BACKGROUND: Prevalence of osteoarthritis (OA) is on rise on the global scale. At present there are no satisfactory pharmacological agents for treating OA. Our previous study showed that Sida cordifolia L. and Zingiber officinale Rosc. had protective effect on cartilage. Here, we describe the effect of OA-F2, a herbal formulation prepared using combination of these two plants in alleviating OA associated symptoms in a rat model of collagenase-induced OA. METHODS: OA was induced by intra-articular injection of collagenase type II in wistar rats...
January 3, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27981254/ginger-zingiber-officinale-induces-apoptosis-in-trichomonas-vaginalis-in-vitro
#5
Mohsen Arbabi, Mahdi Delavari, Zohre Fakhrieh Kashan, Mohsen Taghizadeh, Hossein Hooshyar
BACKGROUND: Trichomoniasis is the most common sexually transmitted protozoan diseases in the worldwide. Metronidazole is the choice drug for trichomoniasis treatment, however, metronidazole resistant Trichomonas vaginalis (T.vaginalis) has been reported. Natural products are the source of most new drugs, and Zingiber officinale (Ginger) is widely used ingredient in the traditional medicine. OBJECTIVE: The aim of the present study was to determine the effect of different concentrations of the ginger ethanol extract on the growth of T...
November 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27975389/the-geographical-discrimination-of-ginger-zingiber-officinale-using-hplc-and-uv-spectroscopy-in-combination-with-chemometric-analysis
#6
M T Abdou, H A Gad, S H El-Ahmady, M M Al-Azizi
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27894973/is-there-nothing-new-under-the-sun-the-influence-of-herbals-and-pharmacopoeias-on-ethnobotanical-traditions-in-albacete-spain
#7
Diego Rivera, Alonso Verde, Concepción Obón, Francisco Alcaraz, Candelaria Moreno, Teresa Egea, José Fajardo, José Antonio Palazón, Arturo Valdés, Maria Adele Signorini, Piero Bruschi
ETHNOPHARMACOLOGICAL RELEVANCE: This paper has two overarching aims: (1) presenting the results of studying the Albacete tariff of medicines of 1526 and (2) broadly analyzing the origin and influences of medicinal traditional knowledge in the region of Albacete, Spain. We use historical and modern literature that may have influenced this knowledge. Our primary goal was to determine the ingredients used in the pharmacy in the 16th century CE in Albacete through the analysis of the tariff, and our secondary goal was to investigate until when ingredients and uses present in pharmacy and herbals persisted in later periods...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27883220/how-long-does-the-volumizing-effect-of-a-zingiber-officinale-based-lip-plumper-last
#8
V Mazzarello, G Solinas, P Bandiera, V Pomponi, G Piu, M Ferrari, A Montella
OBJECTIVE: Lip plumpers should enhance lip volume. It has been shown that no noticeable result was obtained after long term use of these products. The present study has been carried out to assess lip plumpers' short term effectiveness within 2 h from application. METHODS: Effectiveness was assessed using non-invasive techniques. The effect on vascularisation was analyzed with the Mexameter MX 16(®) , and the volume enhancing effect was assessed by anthropometric measures and profilometry analysis from 3D scanning electron microscope (SEM) images using Alicona's MEX software...
November 24, 2016: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/27872812/anti-inflammatory-effects-of-the-essential-oils-of-ginger-zingiber-officinale-roscoe-in-experimental-rheumatoid-arthritis
#9
Janet L Funk, Jennifer B Frye, Janice N Oyarzo, Jianling Chen, Huaping Zhang, Barbara N Timmermann
Ginger and its extracts have been used traditionally as anti-inflammatory remedies, with a particular focus on the medicinal properties of its phenolic secondary metabolites, the gingerols. Consistent with these uses, potent anti-arthritic effects of gingerol-containing extracts were previously demonstrated by our laboratory using an experimental model of rheumatoid arthritis, streptococcal cell wall (SCW)-induced arthritis. In this study, anti-inflammatory effects of ginger's other secondary metabolites, the essential oils (GEO), which contain terpenes with reported phytoestrogenic activity, were assessed in female Lewis rats with SCW-induced arthritis...
July 2016: PharmaNutrition
https://www.readbyqxmd.com/read/27857849/in-vitro-effect-of-seven-essential-oils-on-the-reproduction-of-the-cattle-tick-rhipicephalus-microplus
#10
Rafael Pazinato, Andréia Volpato, Matheus D Baldissera, Roberto C V Santos, Dilmar Baretta, Rodrigo A Vaucher, Janice L Giongo, Aline A Boligon, Lenita Moura Stefani, Aleksandro Schafer Da Silva
The acaricidal effect of seven essential oils was examined in vitro against the cattle tick (Rhipicephalus microplus). Engorged female ticks were manually collected in farms of Southern Brazil and placed into petri dishes (n = 10) in order to test the following oils: juniper (Juniperus communis), palmarosa (Cymbopogon martinii), cedar (Cedrus atlantica), lemon grass (Cymbopogon citratus), ginger (Zingiber officinale), geranium (Pelargonium graveolens) and bergamot (Citrus aurantium var bergamia) at concentrations of 1%, 5%, and 10% each...
November 2016: Journal of Advanced Research
https://www.readbyqxmd.com/read/27817090/optimization-of-physical-conditions-for-the-aqueous-extraction-of-antioxidant-compounds-from-ginger-zingiber-officinale-applying-a-box-behnken-design
#11
Juan Ramírez-Godínez, Judith Jaimez-Ordaz, Araceli Castañeda-Ovando, Javier Añorve-Morga, Verónica Salazar-Pereda, Luis Guillermo González-Olivares, Elizabeth Contreras-López
Since ancient times, ginger (Zingiber officinale) has been widely used for culinary and medicinal purposes. This rhizome possesses several chemical constituents; most of them present antioxidant capacity due mainly to the presence of phenolic compounds. Thus, the physical conditions for the optimal extraction of antioxidant components of ginger were investigated by applying a Box-Behnken experimental design. Extracts of ginger were prepared using water as solvent in a conventional solid-liquid extraction. The analyzed variables were time (5, 15 and 25 min), temperature (20, 55 and 90 °C) and sample concentration (2, 6 and 10 %)...
November 5, 2016: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27816008/in-silico-investigation-into-the-interactions-between-murine-5-ht3-receptor-and-the-principle-active-compounds-of-ginger-zingiber-officinale
#12
Anna E Lohning, Wolfgang Marx, Liz Isenring
Gingerols and shogaols are the primary non-volatile actives within ginger (Zingiber officinale). These compounds have demonstrated in vitro to exert 5-HT3 receptor antagonism which could benefit chemotherapy-induced nausea and vomiting (CINV). The site and mechanism of action by which these compounds interact with the 5-HT3 receptor is not fully understood although research indicates they may bind to a currently unidentified allosteric binding site. Using in silico techniques, such as molecular docking and GRID analysis, we have characterized the recently available murine 5-HT3 receptor by identifying sites of strong interaction with particular functional groups at both the orthogonal (serotonin) site and a proposed allosteric binding site situated at the interface between the transmembrane region and the extracellular domain...
November 2016: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/27782086/laurus-nobilis-zingiber-officinale-and-anethum-graveolens-essential-oils-composition-antioxidant-and-antibacterial-activities-against-bacteria-isolated-from-fish-and-shellfish
#13
Mejdi Snuossi, Najla Trabelsi, Sabrine Ben Taleb, Ameni Dehmeni, Guido Flamini, Vincenzo De Feo
Several bacterial strains were isolated from wild and reared fish and shellfish. The identification of these strains showed the dominance of the Aeromonas hydrophila species in all seafood samples, followed by Staphylococcus spp., Vibrio alginolyticus, Enterobacter cloacae, Klebsiella ornithinolytica, Klebsiella oxytoca and Serratia odorifera. The isolates were studied for their ability to produce exoenzymes and biofilms. The chemical composition of the essential oils from Laurus nobilis leaves, Zingiber officinale rhizomes and Anethum graveolens aerial parts was studied by GC and GC/MS...
October 22, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27774899/spices-therapeutic-potential-in-cardiovascular-health
#14
Subha Rastogi, Madan Mohan Pandey, Aks Rawat
BACKGROUND: Dietary factors play a key role in the development as well as prevention of certain human diseases, including cardiovascular diseases. Currently there has been an increase in global interest to identify medicinal plants that are pharmacologically effective and have low or no side effects for use in preventive medicine. Culinary herbs and spices are an important part of human nutrition in all the cultures of the world. There is a growing amount of literature concerning the potential benefits of these herbs and spices from a health perspective especially in conferring protection against cardiovascular diseases...
October 21, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27774555/electrochemical-detection-and-quantification-of-gingerol-species-in-ginger-zingiber-officinale-using-multiwalled-carbon-nanotube-modified-electrodes
#15
Korbua Chaisiwamongkhol, Kamonwad Ngamchuea, Christopher Batchelor-McAuley, Richard G Compton
We demonstrate the potential of electrochemical detection for the analysis of the 'strength' of ginger in ginger sample. This facile and fast detection method is aimed at the quality control in food industry. Specifically, we report adsorptive stripping voltammetry (AdsSV) as a technique for detection of gingerol compounds, the pungent components of ginger rhizome. Among the gingerols, 6-gingerol is the most abundant and is chosen as a model to characterise the behaviour of a wider range of related compounds...
October 24, 2016: Analyst
https://www.readbyqxmd.com/read/27771925/gingerol-and-its-role-in-chronic-diseases
#16
Yasmin Anum Mohd Yusof
Since antiquity, ginger or Zingiber officinale, has been used by humans for medicinal purposes and as spice condiments to enhance flavor in cooking. Ginger contains many phenolic compounds such as gingerol, shogaol and paradol that exhibit antioxidant, anti-tumor and anti-inflammatory properties. The role of ginger and its constituents in ameliorating diseases has been the focus of study in the past two decades by many researchers who provide strong scientific evidence of its health benefit. This review discusses research findings and works devoted to gingerols, the major pungent constituent of ginger, in modulating and targeting signaling pathways with subsequent changes that ameliorate, reverse or prevent chronic diseases in human studies and animal models...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27765607/gastroprotective-activity-of-the-rhizome-ethanol-extract-of-zingiber-simaoense-y-y-qian-in-rats
#17
Pareeya Baiubon, Puongtip Kunanusorn, Parirat Khonsung, Natthakarn Chiranthanut, Ampai Panthong, Chaiyong Rujjanawate
ETHNOPHARMACOLOGICAL RELEVANCE: Zingiber simaoense Y. Y. Qian belongs to the Zingiberaceae family. Its rhizome has been used in Thai folk medicine to relieve gastric disorders; however, scientific evidence of its pharmacological activities has not yet been revealed. AIM OF THE STUDY: This study was designed to validate the gastroprotective activity and to identify possible mechanisms of gastroprotection of Z. simaoense rhizome ethanol extract (ZSE) in rats. MATERIALS AND METHODS: The gastroprotective effect of ZSE was tested using models of gastric ulcers induced by acidified ethanol, indomethacin, and restraint water immersion stress...
December 24, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27757260/medicinal-plants-used-by-traditional-healers-from-south-west-algeria-an-ethnobotanical-study
#18
Bachir Benarba
BACKGROUND/AIM: This study aimed to document and analyzes the local knowledge of medicinal plants' use by traditional healers in South-west Algeria. METHODS: The ethnobotanical survey was conducted in two Saharian regions of South-west of Algeria: Adrar and Bechar. In total, 22 local traditional healers were interviewed using semi-structured questionnaire and open questions. Use value (UV), fidelity level (FL), and informant consensus factor (FIC) were used to analyze the obtained data...
September 2016: Journal of Intercultural Ethnopharmacology
https://www.readbyqxmd.com/read/27737573/the-effect-and-safety-of-highly-standardized-ginger-zingiber-officinale-and-echinacea-echinacea-angustifolia-extract-supplementation-on-inflammation-and-chronic-pain-in-nsaids-poor-responders-a-pilot-study-in-subjects-with-knee-arthrosis
#19
Mariangela Rondanelli, Antonella Riva, Paolo Morazzoni, Pietro Allegrini, Milena Anna Faliva, Maurizio Naso, Alessandra Miccono, Gabriella Peroni, Irene Degli Agosti, Simone Perna
The study aimed to evaluate the effect of Zingiber officinale and Echinacea angustifolia extract supplementation (25 mg of ginger and 5 mg of Echinacea) for 30 days on inflammation and chronic pain in knee osteoarthritis (OA). Consecutive nonsteroidal anti-inflammatory-drugs (NSAIDs) poor responders with chronic inflammation and pain due to knee arthrosis were assessed (15 subjects, age: 67.2 ± 7.9, body mass index: 30.6 ± 7.1, men/women:2/13). The primary endpoint was to determine pain improvement from baseline to Day 30 by Tegner Lysholm Knee Scoring...
October 13, 2016: Natural Product Research
https://www.readbyqxmd.com/read/27722803/genetic-diversity-and-structure-of-brazilian-ginger-germplasm-zingiber-officinale-revealed-by-aflp-markers
#20
Eleonora Zambrano Blanco, Miklos Maximiliano Bajay, Marcos Vinícius Bohrer Monteiro Siqueira, Maria Imaculada Zucchi, José Baldin Pinheiro
Ginger is a vegetable with medicinal and culinary properties widely cultivated in the Southern and Southeastern Brazil. The knowledge of ginger species' genetic variability is essential to direct correctly future studies of conservation and genetic improvement, but in Brazil, little is known about this species' genetic variability. In this study, we analyzed the genetic diversity and structure of 55 Brazilian accessions and 6 Colombian accessions of ginger, using AFLP (Amplified Fragment Length Polymorphism) molecular markers...
December 2016: Genetica
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