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https://www.readbyqxmd.com/read/29642672/phytochemicals-and-antioxidant-capacity-from-some-tropical-edible-plants
#1
Heeok Hong, Jun-Hyeong Lee, Soo-Ki Kim
Objective: To find biological functions such as antibacterial and antioxidant activities in several tropical plants and to investigate the possibility of antibiotic substitute agents to prevent and treat diseases caused by pathogenic bacteria. Methods: Those plants such as Poncirus trifoliata fruit (Makrut), Zingiber officinale Rosc (Khing), Areca catechu L. (Mak), Solanum melongena L. I (Makkhuayao), and Solanum melongena L. II (Makhurapro) were extracted by methanol, n-hexane, chloroform, ethyl acetate, butanol and water...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29622202/simultaneous-extraction-of-hydrophobic-and-hydrophilic-bioactive-compounds-from-ginger-zingiber-officinale-roscoe
#2
Xingran Kou, Yuqian Ke, Xiaoqi Wang, Md Ramim Tanver Rahman, Yuzhang Xie, Shangwei Chen, Hongxin Wang
Ginger is a commonly used spice around the world. Its bioactive compounds contain hydrophobic gingerols and hydrophilic polysaccharides. Huge physiochemical differences between these compounds and the thermal instability of gingerols impede fast and effective extraction of them using conventional methods. In this research, ionic liquid-based ultrasonic-assisted extraction (ILUAE) was applied to simultaneously extract gingerols and polysaccharides from ginger. Parameters influencing the recovery of gingerols were ionic liquid type, ionic liquid concentration, solid/liquid ratio, ultrasonic power, extraction temperature and extraction time...
August 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29618440/synergistic-potential-of-zingiber-officinale-and-curcuma-longa-to-ameliorate-diabetic-dyslipidemia
#3
Naveed Hussain, Abu-Saeed Hashmi, Muhammad Wasim, Tauqeer Akhtar, Shagufta Saeed, Toheed Ahmad
To find the cure of world's one of the leading morbid and mortal disorders; diabetes mellitus and its most prevalent complication, 'diabetic-dyslipidemia', is one of the leading health challenges of 21st century. The use of phytomedicine is a glimmer of hope in this scenario. Studies of current decade have shown that methanolic extracts of Zingiber officinale and Curcuma longa have highly effective therapeutic potentials against the aforesaid disorders, however, which of the extracts has more potential is still unclear...
March 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29614764/how-safe-is-ginger-rhizome-for-decreasing-nausea-and-vomiting-in-women-during-early-pregnancy
#4
REVIEW
Julien Stanisiere, Pierre-Yves Mousset, Sophie Lafay
Ginger, Zingiber officinale Roscoe, is increasingly consumed as a food or in food supplements. It is also recognized as a popular nonpharmacological treatment for nausea and vomiting of pregnancy (NVP). However, its consumption is not recommended by all countries for pregnant women. Study results are heterogeneous and conclusions are not persuasive enough to permit heath care professionals to recommend ginger safely. Some drugs are also contraindicated, leaving pregnant women with NVP with few solutions. We conducted a review to assess effectiveness and safety of ginger consumption during early pregnancy...
April 1, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29609660/ginger-zingiber-officinale-phytochemicals-gingerenone-a-and-shogaol-inhibit-sahppk-molecular-docking-molecular-dynamics-simulations-and-in-vitro-approaches
#5
Shailima Rampogu, Ayoung Baek, Rajesh Goud Gajula, Amir Zeb, Rohit S Bavi, Raj Kumar, Yongseong Kim, Yong Jung Kwon, Keun Woo Lee
BACKGROUND: Antibiotic resistance is a defense mechanism, harbored by pathogens to survive under unfavorable conditions. Among several antibiotic resistant microbial consortium, Staphylococcus aureus is one of the most havoc microorganisms. Staphylococcus aureus encodes a unique enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (SaHPPK), against which, none of existing antibiotics have been reported. METHODS: Computational approaches have been instrumental in designing and discovering new drugs for several diseases...
April 2, 2018: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29605868/6-gingerol-ameliorates-behavioral-changes-and-atherosclerotic-lesions-in-apoe-mice-exposed-to-chronic-mild-stress
#6
Shuai Wang, Miao Tian, Ronglai Yang, Yating Jing, Wei Chen, Jinliang Wang, Xian Zheng, Fengrong Wang
Chronic mild stress (CMS) has been demonstrated to contribute to atherosclerosis. 6-gingerol (6-Gin), a phenolic component of ginger (Zingiber officinale), has been shown to exert numerous pharmacological properties, such as anti-inflammatory and cardioprotective effects. Here we investigated the role of CMS in the development of atherosclerosis in high-fat diet (HFD)-fed ApoE-/- mice and evaluated the potential therapeutic effects of 6-Gin. Mice were exposed to CMS for 20 weeks, at week 5, they were fed with a high-fat diet (HFD), then received 6-Gin (20 mg/kg/day, intragastrically) treatment...
March 31, 2018: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/29600613/-identification-and-analysis-of-nac-family-in-ginger-zingiber-officinale-based-on-rna-seq-data
#7
Qin-Hong Liao, Youg Zou, Hong-Lei Li, Yu-Song Jiang
The NAC family is an important transcription factor which regulate plant growth and development, signal transduction, and stress response.In this study, the protein identification, subfamily classification, the determination of physical and chemical properties, protein structure, and expression pattern of NAC family were performed using bioinformatic methods based on the RNA-seq data of ginger. The results showed that a total of 72 NAC transcription factors were identified in 271.1 Mb total nucleotides, and they could be clustered into 13 subfamilies according to the phylogenetic tree...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29600411/differential-modulation-of-endophytic-microbiome-of-ginger-in-the-presence-of-beneficial-organisms-pathogens-and-both-as-identified-by-dgge-analysis
#8
Rohini Sabu, R Aswani, Priya Prabhakaran, B Krishnakumar, E K Radhakrishnan
Endophytic microorganisms play a significant role in plants response to beneficial organisms and pathogens. In the current study, endophytic microorganisms from Zingiber officinale were screened for in vitro inhibition against Pythium myriotylum. From this, Burkholderia vietnamiensis ZoB74 was selected as an organism with remarkable antifungal effect. Further, the study focussed on analysis of in vivo changes in endophytic bacterial community of Z. officinale in presence of selected organisms and the pathogen P...
March 29, 2018: Current Microbiology
https://www.readbyqxmd.com/read/29595889/dietary-onion-or-ginger-modulates-the-stress-response-and-susceptibility-to-vibrio-harveyi-jml1-infection-in-brown-marbled-grouper-epinephelus-fuscoguttatus-juveniles
#9
E C Amar, M J S Apines-Amar, J P Faisan
Onion Allium cepa and ginger Zingiber officinale have health-promoting properties that qualify them as functional foods. The effect of repeated acute stressors was examined in juvenile Brown-marbled Grouper Epinephelus fuscoguttatus that were fed four diets supplemented with onion at 1.8%, ginger at 1.8%, vitamin C at 0.86%, and β-glucan at 0.8% of the diet. The non-supplemented diet served as the control. After 12 weeks of feeding, fish were exposed to stressors and were experimentally infected with a fish pathogen, the bacterium Vibrio harveyi JML1...
March 2018: Journal of Aquatic Animal Health
https://www.readbyqxmd.com/read/29576593/in-vitro-inhibitory-effects-of-two-bornean-medicinal-wild-gingers-against-pathogenic-lagenidium-thermophilum-infected-mud-crab-scylla-tranquebarica
#10
Kishio Hatai, Takashi Kamada, Lik-Ming Lau, Julius Kulip, Chin-Soon Phan, Charles Santhanaraju Vairappan
 The antifungal activity of two Bornean medicinal wild gingers Plagiostachys megacarpa and Zingiber phillippsiae were examined against Lagenidium thermophilum. The most active extract was P. megacarpa at concentration of 320 µg/mL inhibiting both hyphal growth and zoospore production of L. thermophilum in 24 h. Toxicity tests were conducted using mud crab (Scylla tranquebarica) larva. Bath treatment of P. megacarpa at concentrations of 320 and 640 µg/mL for 24 h were highly effective against hyphae and zoospores of the strain and it is non-toxic to mud crab larva...
2018: Biocontrol Science
https://www.readbyqxmd.com/read/29558939/zingiber-zerumbet-l-smith-extract-alleviates-the-ethanol-induced-brain-damage-via-its-antioxidant-activity
#11
Asmah Hamid, Farah Wahida Ibrahim, Teoh Hooi Ming, Mohd Nazir Nasrom, Norelina Eusoff, Khairana Husain, Mazlyzam Abdul Latif
BACKGROUND: Zingiber zerumbet (L.) Smith belongs to the Zingiberaceae family that is widely distributed throughout the tropics, particularly in Southeast Asia. It is locally known as 'Lempoyang' and traditionally used to treat fever, constipation and to relieve pain. It is also known to possess antioxidant and anti-inflammatory activities. Based on these antioxidant and anti-inflammatory activities, this study was conducted to investigate the effects of ethyl-acetate extract of Z. zerumbet rhizomes against ethanol-induced brain damage in male Wistar rats...
March 20, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29541142/effects-of-ginger-zingiber-officinale-roscoe-on-type-2-diabetes-mellitus-and-components-of-the-metabolic-syndrome-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#12
REVIEW
Jie Zhu, Hao Chen, Zhixiu Song, Xudong Wang, Zhenshuang Sun
Objective: This article aims to assess the effects of ginger (Zingiber officinale Roscoe) on type 2 diabetes mellitus (T2DM) and/or components of the metabolic syndrome (MetS). Methods: Electronic literature was searched in PubMed, Embase, the Cochrane Library, Chinese Biomedical Database, China National Knowledge Infrastructure, and Wanfang Database from inception of the database to May 19, 2017, and supplemented by browsing reference lists of potentially eligible articles...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29534560/longevity-and-stress-resistant-property-of-6-gingerol-from-zingiber-officinale-roscoe-in-caenorhabditis-elegans
#13
Eun Byeol Lee, Jun Hyeong Kim, Chang Wan An, Yeong Jee Kim, Yun Jeong Noh, Su Jin Kim, Ju-Eun Kim, Abinash Chandra Shrestha, Ha-Neul Ham, Jae-Yoon Leem, Hyung-Kwon Jo, Dae-Sung Kim, Kwang Hyun Moon, Jeong Ho Lee, Kyung Ok Jeong, Dae Keun Kim
In order to discover lifespan-extending compounds made from natural resources, activity-guided fractionation of Zingiber officinale Roscoe (Zingiberaceae) ethanol extract was performed using the Caenorhabditis elegans ( C. elegans ) model system. The compound 6-gingerol was isolated from the most active ethyl acetate soluble fraction, and showed potent longevity-promoting activity. It also elevated the survival rate of worms against stressful environment including thermal, osmotic, and oxidative conditions...
March 14, 2018: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/29512739/-6-gingerol-enhances-the-radiosensitivity-of-gastric-cancer-via-g2-m-phase-arrest-and-apoptosis-induction
#14
Youjun Luo, Xue Chen, Lumeng Luo, Qi Zhang, Caixia Gao, Xibing Zhuang, Sujuan Yuan, Tiankui Qiao
Ionizing radiation (IR) is the main modality for locoregional control of unresectable gastric cancer (GC). [6]-Gingerol is an active major phenolic compound isolated from ginger (Zingiber officinale Roscoe), and it has been demonstrated to possess antitumor activity in previous studies. In the present study, we aimed to evaluate the potential activity of [6]-gingerol as a radiosensitizer and to further explore the underlying mechanism. A CCK-8 assay revealed that [6]-gingerol inhibited the cell viability of HGC-27 cells in a dose-dependent manner (P<0...
March 5, 2018: Oncology Reports
https://www.readbyqxmd.com/read/29485633/effects-of-fermented-ginger-rhizome-zingiber-officinale-and-fenu-greek-trigonella-foenum-graceum-supplements-on-oxidative-stress-and-lipid-peroxidation-biomarkers-in-poloxamer-407-induced-hyperlipidemic-wistar-rats
#15
Y Tanko, A Kabiru, A Abdulrasak, K A Mohammed, A I Salisu, A Jimoh, N M Gidado, N M Sada
This research was aimed at investigating the Effects of Fermented Ginger Rhizome (Zingiber officinale) and Fenu Greek (Trigonella foenum-graceum) on Oxidative stress and Lipid Peroxidation Biomarkers in Poloxamer 407Induced-Hyperlipidemic Wistar Rats. Hyperlipidaemia was induced with poloxamer P407 (1.5 g/kg   b.w. i.p.) The Animals were grouped into six of five animals each group. Group 1 normal control, Group 2 served as the hyperlipidemic control, Group 3 administered 0.26 g/kg cholestyramine, Group 4 fed on Fenugreek 25% supplement...
December 30, 2017: Nigerian Journal of Physiological Sciences: Official Publication of the Physiological Society of Nigeria
https://www.readbyqxmd.com/read/29472791/antimicrobial-activity-of-some-plant-extracts-against-bacterial-strains-causing-food-poisoning-diseases
#16
Ashraf A Mostafa, Abdulaziz A Al-Askar, Khalid S Almaary, Turki M Dawoud, Essam N Sholkamy, Marwah M Bakri
Prevention of food spoilage and food poisoning pathogens is usually achieved by use of chemical preservatives which have negative impacts including: human health hazards of the chemical applications, chemical residues in food & feed chains and acquisition of microbial resistance to the used chemicals. Because of such concerns, the necessity to find a potentially effective, healthy safer and natural alternative preservatives is increased. Within these texts, Plant extracts have been used to control food poisoning diseases and preserve foodstuff...
February 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29471237/quantifying-the-harmful-potential-of-ten-essential-oils-on-immature-trichogramma-pretiosum-stages
#17
Douglas Silva Parreira, Ricardo Alcántara-de la Cruz, Germano Leão Demolin Leite, Francisco de Souza Ramalho, José Cola Zanuncio, José Eduardo Serrão
The use of chemical insecticides and non-selective natural products authorized for use in organic farming may reduce the effectiveness of egg parasitoids. The side-effects of ten plant essential oils on immature stages of Trichogramma pretiosum were evaluated. Carapa guianensis, Origanum vulgare and Zingiber officinalle during the F1 generation, and Azadirachtin and Mentha piperita in the F2 generation were slightly harmful (class II: 30-79%) to the emergence of this parasitoid. All essential oils affected the longevity of females of the F1 and F2 generations...
February 14, 2018: Chemosphere
https://www.readbyqxmd.com/read/29467652/quantitative-ethnobotany-of-medicinal-plants-used-by-indigenous-communities-in-the-bandarban-district-of-bangladesh
#18
Mohammad O Faruque, Shaikh B Uddin, James W Barlow, Sheng Hu, Shuang Dong, Qian Cai, Xiaohua Li, Xuebo Hu
This study documents information on significant ethnomedicinal plants, which was collected from the traditional healers of three indigenous communities of Bangladesh. The documented data were quantitatively analyzed for the first time in this area. The information was obtained through open-ended, semi-structured questionnaires. The benefits, importance and coverage of ethnomedicine were expressed through several quantitative indices including Informant Consensus Factor (ICF), Use Value (UV), Frequency of Citation (FC), Relative Frequency of Citation (RFC) and Relative Importance Index (RI)...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29454952/probing-the-interaction-of-the-phytochemical-6-gingerol-from-the-spice-ginger-with-dna
#19
Poovvathingal Haris, Varughese Mary, Chellappanpillai Sudarsanakumar
6-Gingerol [5-hydroxy-1-(4-hydroxy-3-methoxyphenyl) decan-3-one], the bio-active ingredient of the popular Indian spice ginger (Zingiber officinale Roscoe), is well-known for its pharmacological and physiological actions. The potent antioxidant, antiemetic, antiulcer, antimicrobial, analgesic, hypoglycemic, antihypertensive, antihyperlipidemic, immunostimulant, anti-inflammatory, cardiotonic, and cancer prevention activities of 6-Gingerol has been investigated and explored. 6-Gingerol is a good candidate for the treatment of various cancers including prostrate, pancreatic, breast, skin, gastrointestinal, pulmonary, and renal cancer...
February 16, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29450200/nutritional-compositions-and-phytochemical-properties-of-the-edible-flowers-from-selected-zingiberaceae-found-in-thailand
#20
Apinya Rachkeeree, Kuttiga Kantadoung, Ratchuporn Suksathan, Ratchadawan Puangpradab, Paul Alexander Page, Sarana Rose Sommano
The nutritional compositions and phytochemical properties of eight edible flowers of the ginger family (Zingiberaceae) commonly found in Thailand are reported herein. The plant genera investigated were Zingiber (Ginger, Phlai Dam, Krathue), Hedychium (two morphological filament forms), Curcuma (Ao), Etlingera (Torch ginger), Amomum (Chi Kuk), and Alpinia (Galangal), which are eaten fresh or cooked as ingredients in the preparation of many Thai dishes. The proximate compositions (moisture, ash, fiber, protein, fat, and carbohydrate contents) varied among the different genera...
2018: Frontiers in Nutrition
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