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https://www.readbyqxmd.com/read/29235659/effect-of-metabolic-syndrome-on-late-life-depression-associations-with-disease-severity-and-treatment-resistance
#1
John S Mulvahill, Ginger E Nicol, David Dixon, Eric J Lenze, Jordan F Karp, Charles F Reynolds, Daniel M Blumberger, Benoit H Mulsant
BACKGROUND/OBJECTIVES: Metabolic syndrome (MetS) is the co-occurrence of obesity and metabolic derangements. Prior research implicates MetS in prolongation of the course of depression in older adults, but its effect on antidepressant response is unknown in this population. The objective was to determine whether MetS and related metabolic dyscrasias are associated with decreased rate of remission from depression in older adults treated pharmacologically for depression. DESIGN: Secondary analysis of a randomized controlled trial...
December 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29231593/-impacts-on-urodynamic-parameters-and-the-protein-expressions-of-m2-and-m3-receptors-of-detrusor-in-the-rats-of-detrusor-hyperreflexia-treated-with-ginger-salt-isolated-moxibustion-at-shenque-cv-8
#2
Yi Liu, Xuerui Wang, Tianran Li, Liting Lin, Guangxia Shi, Yuanbo Fu, Cunzhi Liu
OBJECTIVE: To discuss the effects on detrusor hyperreflexia treated with ginger-salt-isolated moxibustion at "Shenque" (CV 8) and its mechanism. METHODS: Thirty female adult SD rats were selected. The model of detrusor hyperreflexia was prepared with complete spinal transection at T9, of which, 20 rats were randomized into a model group (10 rats) and a moxibustion group (10 rats). A sham-operation group (10 rats) was set up for sham-spinal transection. In the moxibustion group, when urine incontinence occurred (about in 2 weeks of modeling), the ginger-salt-isolated moxibustion at "Shenque" (CV 8) was given, 3 moxa cones each time, once a day, continuously for 7 days...
April 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29231499/-different-acupuncture-and-moxibustion-methods-at-heding-ex-le-2-for-knee-osteoarthritis-with-yang-deficiency-and-cold-stagnation-syndrome
#3
Jia Zheng, Hui Zhang, Jianwu Liu
OBJECTIVE: To observe the differences for knee osteoarthritis (KOA) with yang-deficiency and cold-stagnation syndrome among acupuncture plus ginger moxibustion at Heding (EX-LE 2) on the affected side, simple acupuncture and simple ginger moxibustion at the same acupoint. METHODS: Ninety patients were randomly assigned into an acupuncture group, a ginger moxibustion group and a combination group, 30 cases in each one. Acupuncture was used in the three groups at bilateral Liangqiu (ST 34), Xuehai (SP 10), and Dubi (ST 35), Neixiyan (EX-LE 4), Yanglingquan (GB 34), Zusanli (ST 36), Yinlingquan (SP 9), Sanyinjiao (SP 6), Xuanzhong (GB 39), Taichong (LR 3) on the affected side...
June 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29231339/-efficacy-of-acupoint-catgut-embedding-combined-with-ginger-partitioned-moxibustion-on-chronic-fatigue-syndrome-of-spleen-kidney-yang-deficiency-syndrome-and-its-effects-on-t-lymphocyte-subsets-and-activity-of-nk-cell
#4
Depeng Xia, Peifang Chen, Peixue Du, Lijun Ding, Anli Liu
OBJECTIVE: To observe the efficacy differences between acupoint catgut embedding combined with ginger-partitioned moxibustion and regular acupuncture on chronic fatigue syndrome (CFS) of spleen-kidney yang deficiency syndrome, and to explore its effects on T lymphocyte subsets and activity of NK cell. METHODS: A total of 60 patients with CFS of spleen-kidney yang deficiency syndrome were randomly divided into a catgut embedding combined with ginger-partitioned moxibustion (CECGP) group and a regular acupuncture group, 30 cases in each one...
August 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29229550/cardiovascular-disease-risk-factors-and-oxidative-stress-among-premenopausal-women
#5
Chelsea Anderson, Ginger L Milne, Yong-Moon Mark Park, Dale P Sandler, Hazel B Nichols
Oxidative stress is one hypothesized mechanism linking anthropometric, behavioral, and medical risk factors with cardiovascular disease (CVD). We evaluated cross-sectional associations between CVD risk factors and biomarkers of oxidative stress, and investigated these biomarkers as predictors of incident diabetes and hypertension among premenopausal women. F2-isoprostane (F2-IsoP) and metabolite (15-F2t-IsoP-M), reliable biomarkers of oxidative stress, were measured in urine samples collected at enrollment from 897 premenopausal women (ages 35-54) enrolled in the Sister Study cohort without a CVD history...
December 8, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29228791/the-protective-effect-of-hydroalcoholic-extract-of-zingiber-officinale-roscoe-ginger-on-ethanol-induced-reproductive-toxicity-in-male-rats
#6
Abolfazl Akbari, Khadijeh Nasiri, Mojtaba Heydari, Seyed Hamdollah Mosavat, Aida Iraji
This study was conducted to evaluate the prophylactic effect of ginger extract on ethanol-induced reproductive toxicity in male rats. Twenty-eight adult male Sprague-Dawley rats were randomly divided into 4 groups and treated daily for 28 days as follows: control, control-ginger (1 g/kg of body weight [BW]/day by gavage), ethanol group (ethanol 4 g/kg of BW/day by gavage), and ginger-ethanol group. At the end of the experiment, all the rats were sacrificed and their testes were removed and used for measurement of the total homocysteine (tHcy), trace elements, antioxidant enzymes activity, and malondialdehyde (MDA)...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29226749/is-ginger-really-effective-for-the-treatment-of-the-first-trimester-nausea-and-vomiting
#7
Ahmed M Abbas
No abstract text is available yet for this article.
December 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29218571/culturable-endophytic-bacteria-of-ginger-rhizome%C3%A2-and-their-remarkable-multi-trait-plant-growth-promoting-features
#8
Sabu Rohini, R Aswani, M Kannan, V P Sylas, E K Radhakrishnan
Functional contribution of endophytic bacteria towards plant growth is highly impressive due to their species diversity and array of probiotic mechanisms. In the study, 96 endophytic bacteria isolated from rhizome of ginger (Zingiber officinale) were screened for phosphate solubilisation, 1-amino cyclopropane-1-carboxylate (ACC) deaminase activity, nitrogen fixation, ammonia and IAA production. Among these, sixteen endophytes with multiple plant growth-promoting activities were identified by 16S rDNA sequencing and all of them showed growth enhancement in Vigna unguiculata var Lola which make the study remarkably significant...
December 7, 2017: Current Microbiology
https://www.readbyqxmd.com/read/29214818/colorectal-cancer-screening-completion-among-individuals-with-and-without-mental-illnesses-a-comparison-of-2-screening-methods
#9
Bobbi Jo H Yarborough, Ginger C Hanson, Nancy A Perrin, Scott P Stumbo, Carla A Green
PURPOSE: Cancer mortality is worse among people with psychiatric disorders. The purpose of this study was to compare facilitators and rates of colorectal cancer (CRC) screening between people with and without mental illnesses. DESIGN: We conducted a secondary analysis using data from a general population cohort study (N = 92 445) that assessed effects of 2 types of CRC screening test kits-guaiac fecal occult blood testing (gFOBT) and fecal immunochemical testing (FIT)-on CRC screening completion...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29203360/the-genetics-of-seborrheic-dermatitis-a-candidate-gene-approach-and-pilot-genome-wide-association-study
#10
Martijn G H Sanders, Luba M Pardo, André G Uitterlinden, Adrian M Smith, Rebecca S Ginger, Tamar Nijsten
No abstract text is available yet for this article.
December 1, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29201493/analysis-of-microbial-diversity-in-soil-under-ginger-cultivation
#11
Yiqing Liu, Lin Wu, Xingwen Wu, Honghai Li, Qinhong Liao, Xiaojing Zhang, Zhiqiang Sun, Wenhua Li
Ginger is a perennial monocotyledonous herb, which can be used as both a vegetable and a medicinal plant. However, it is susceptible to various plant pathogens. Microbial diversity in soil is related closely to the health and productivity of plant crops including ginger. In the current study, we compared microbial diversity from soil samples under ginger cultivation (disease incidence of >50% [relatively unhealthy sample] versus disease incidence of <10% [relatively healthy sample]). The bacterial and fungal taxa were analyzed by Illumina-based sequencing, with 16S and ITS identification, respectively...
2017: Scientifica
https://www.readbyqxmd.com/read/29196903/concurrent-use-of-prescription-drugs-and-herbal-medicinal-products-in-older-adults-a-systematic-review
#12
REVIEW
Taofikat B Agbabiaka, Barbara Wider, Leala K Watson, Claire Goodman
BACKGROUND: The use of herbal medicinal products (HMPs) is common among older adults; however, little is known about concurrent use with prescription drugs, as well as potential interactions associated with such combinations. OBJECTIVE: The aim of this systematic review was to identify and evaluate the literature on concurrent prescription and HMP use among older adults to assess prevalence, patterns, potential interactions and factors associated with this use. METHODS: Systematic searches were conducted in the MEDLINE, PsycINFO, EMBASE, CINAHL, AMED, Web of Science and Cochrane databases from inception to May 2017 for studies reporting concurrent use of prescription medicines with HMPs in adults ≥ 65 years of age...
December 1, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/29193411/a-systematic-review-of-the-anti-obesity-and-weight-lowering-effect-of-ginger-zingiber-officinale-roscoe-and-its-mechanisms-of-action
#13
REVIEW
Vahideh Ebrahimzadeh Attari, Aida Malek Mahdavi, Zeinab Javadivala, Sepideh Mahluji, Sepideh Zununi Vahed, Alireza Ostadrahimi
Recently, the beneficial effects of ginger on obesity is taken into consideration. Albeit, it seems that the anti-obesity effect of ginger and its mechanism of action has not yet been reviewed. Therefore, the aim of this study was to systematically review the effect of Zingiber officinale Roscoe on obesity management. Databases including PubMed, Scopus, Google scholar, and Science Direct were searched from 1995 until May 2017 using the definitive keywords. Searching was limited to articles with English language...
November 29, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29188416/production-of-an-emericellin-and-its-analogues-as-fungal-biological-responses-for-shimbu-to-extract
#14
Nobuhiro Inoue, Daigo Wakana, Hisashi Takeda, Takashi Yaguchi, Tomoo Hosoe
This research examined the production of fungal metabolites as a biological response to Kampo medicines. Shimbu-to (SMB) is a Kampo medicine composed of five herbal components: peony root (Shakuyaku), ginger (Shokyo), processed aconite root (Bushi), Poria sclerotium (Bukuryo), and Atractylodes lancea rhizomes (Sojutsu). High-performance liquid chromatography (HPLC) analysis of the fungus Aspergillus nidulans CBS 112.46 incubated in potato dextrose broth supplemented with SMB extract revealed emericellin (2) as the major peak and new xanthone analogues 24-hydroxyshamixanthone (1), shamixanthone (3), epishamixanthone (4), pre-shamixanthone (5), and variecoxanthone A (6) as minor peaks...
November 29, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/29188046/influence-of-particle-size-and-extraction-solvent-on-antioxidant-properties-of-extracts-of-tea-ginger-and-tea-ginger-blend
#15
Solomon A Makanjuola
The influence of particle size and extraction solvent on the antioxidant properties of aqueous and ethanolic extracts of tea (Camellia sinensis), ginger (Zingiber officinale), and tea-ginger (2:1) blend was investigated. The powder sizes studied were 0.425, 0.710, and 1.180 mm. Extracts were analyzed for DPPH radical scavenging activity, ABTS radical scavenging activity, total phenol content (TPC), iron chelating activity, total flavonoid content, and peroxide scavenging activity. The powder with the lowest particle size of 0...
November 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/29187559/reprograming-of-glucose-metabolism-by-zerumbone-suppresses-hepatocarcinogenesis
#16
Nissar Wani, Bo Zhang, Kun-Yu Teng, Juan Barajas, Tasneem Motiwala, Peng Hu, Lianbo Yu, Rafael Brüschweiler, Kalpana Ghoshal, Samson T Jacob
Hepatocellular carcinoma (HCC) is the most prevalent and a highly aggressive liver malignancy with limited therapeutic options. Here, the therapeutic potential of zerumbone, a sesquiterpene derived from the ginger plant Zingiber zerumbet, against HCC was explored. Zerumbone inhibited proliferation and clonogenic survival of HCC cells in a dose-dependent manner by arresting cell at the G2/M phase, and inducing apoptosis. To elucidate the underlying molecular mechanism, a phosphokinase array was performed that showed significant inhibition of the PI3K/AKT/mTOR and STAT3 signaling pathways in zerumbone treated HCC cells...
November 29, 2017: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/29187420/bayesian-diallel-analysis-reveals%C3%A2-mx1-dependent-and%C3%A2-mx1-independent-effects-on-response-to-influenza-a-virus-in-mice
#17
Paul L Maurizio, Martin T Ferris, Gregory R Keele, Darla R Miller, Ginger D Shaw, Alan C Whitmore, Ande West, Clayton R Morrison, Kelsey E Noll, Kenneth S Plante, Adam S Cockrell, David W Threadgill, Fernando Pardo-Manuel de Villena, Ralph S Baric, Mark T Heise, William Valdar
Influenza A virus (IAV) is a respiratory pathogen that causes substantial morbidity and mortality during both seasonal and pandemic outbreaks. Infection outcomes in unexposed populations are affected by host genetics, but this host genetic architecture is not well understood. Here we obtain a broad view of how heritable factors affect a mouse model of response to IAV infection using an 8×8 diallel of the eight inbred founder strains of the Collaborative Cross (CC). Expanding on a prior statistical framework for modeling treatment response in diallels, we explore how a range of heritable effects modify acute host response to IAV through 4 days post-infection...
November 29, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29184437/antiallodynic-and-antihyperalgesic-activities-of-zerumbone-via-the-suppression-of-il-1%C3%AE-il-6-and-tnf-%C3%AE-in-a-mouse-model-of-neuropathic-pain
#18
Banulata Gopalsamy, Ahmad Akira Omar Farouk, Tengku Azam Shah Tengku Mohamad, Mohd Roslan Sulaiman, Enoch Kumar Perimal
Background: Neuropathic pain is a debilitating condition that severely affects the quality of life for those with this pain condition, and treatment for pain relief is greatly sought-after. Zerumbone (Zer), a sesquiterpene compound isolated from the rhizomes of a Southeast Asian ginger plant, Zingiber zerumbet (L.) Roscoe ex Smith. (Zingiberaceae), showed antinociceptive and antiinflammatory properties when previously tested on models of nociception and inflammation. Objective: This study investigated the effects of prophylactic administration of zerumbone on allodynia and hyperalgesia in a mouse model of chronic constriction injury (CCI)-induced neuropathic pain...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29184033/networks-of-enzymatically-oxidized-membrane-lipids-support-calcium-dependent-coagulation-factor-binding-to-maintain-hemostasis
#19
Sarah N Lauder, Keith Allen-Redpath, David A Slatter, Maceler Aldrovandi, Anne O'Connor, Daniel Farewell, Charles L Percy, Jessica E Molhoek, Sirpa Rannikko, Victoria J Tyrrell, Salvatore Ferla, Ginger L Milne, Alastair W Poole, Christopher P Thomas, Samya Obaji, Philip R Taylor, Simon A Jones, Phillip G de Groot, Rolf T Urbanus, Sohvi Hörkkö, Stefan Uderhardt, Jochen Ackermann, P Vince Jenkins, Andrea Brancale, Gerhard Krönke, Peter W Collins, Valerie B O'Donnell
Blood coagulation functions as part of the innate immune system by preventing bacterial invasion, and it is critical to stopping blood loss (hemostasis). Coagulation involves the external membrane surface of activated platelets and leukocytes. Using lipidomic, genetic, biochemical, and mathematical modeling approaches, we found that enzymatically oxidized phospholipids (eoxPLs) generated by the activity of leukocyte or platelet lipoxygenases (LOXs) were required for normal hemostasis and promoted coagulation factor activities in a Ca2+- and phosphatidylserine (PS)-dependent manner...
November 28, 2017: Science Signaling
https://www.readbyqxmd.com/read/29181121/ginger-oleoresin-alleviated-%C3%AE-ray-irradiation-induced-reactive-oxygen-species-via-the-nrf2-protective-response-in-human-mesenchymal-stem-cells
#20
Kaihua Ji, Lianying Fang, Hui Zhao, Qing Li, Yang Shi, Chang Xu, Yan Wang, Liqing Du, Jinhan Wang, Qiang Liu
Unplanned exposure to radiation can cause side effects on high-risk individuals; meanwhile, radiotherapies can also cause injury on normal cells and tissues surrounding the tumor. Besides the direct radiation damage, most of the ionizing radiation- (IR-) induced injuries were caused by generation of reactive oxygen species (ROS). Human mesenchymal stem cells (hMSCs), which possess self-renew and multilineage differentiation capabilities, are a critical population of cells to participate in the regeneration of IR-damaged tissues...
2017: Oxidative Medicine and Cellular Longevity
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