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https://www.readbyqxmd.com/read/29040187/palliative-radiation-therapy-for-recurrent-ovarian-cancer-efficacy-and-predictors-of-clinical-response
#1
Ginger Jiang, Tracy Balboni, Allison Taylor, Joyce Liu, Larissa J Lee
OBJECTIVE: This study aimed to report response rates and predictors of response to palliative radiotherapy (RT) for recurrent ovarian cancer. METHODS/MATERIALS: Database review identified 64 patients with symptomatic ovarian cancer recurrence who received a total of 76 courses of RT for 103 indications from March 2003 to August 2014. Radiotherapy indications were pain (44%), bleeding (32%), obstruction (15%), and other (9%). Responses were categorized as complete, partial, or none; all response (AR) was the sum of complete and partial responses...
October 17, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29039335/anti-avian-influenza-virus-h9n2-activity-of-aqueous-extracts-of-zingiber-officinalis-ginger-and-allium-sativum-garlic-in-chick-embryos
#2
Amir Rasool, Muti-Ur-Rehman Khan, Muhammad Asad Ali, Aftab Ahmad Anjum, Ishtiaq Ahmed, Asim Aslam, Ghulam Mustafa, Saima Masood, Muhammad Amjad Ali, Muhammad Nawaz
In the present study, anti-Avian influenza virus H9N2 activity of aqueous extracts (5, 10, 15, 20, 25%) of Zingiber officinalis and Allium sativum was evaluated. Embryo-toxicity was evaluated by histopathological scoring of Chorio-allantoic membrane of chick embryos. Cytotoxicity of extracts was determined by MTT assay on Vero cells. Aqueous extract of ginger had antiviral activity at 10, 15, 20 and 25% while garlic had activity at 15, 20 and 25%. Histopathological scoring of chorio-allantoic membrane for aqueous extracts (5, 10, 15, 20, 25%) of ginger (0...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29030875/protection-of-grain-products-from-sitophilus-oryzae-l-contamination-by-anti-insect-pest-repellent-sachet-containing-allyl-mercaptan-microcapsule
#3
Yoonjee Chang, Soo-Hyun Lee, Ja Hyun Na, Pahn-Shick Chang, Jaejoon Han
The purpose of this study was to develop an anti-insect pest repellent sachet to prevent Sitophilus oryzae (L.) (Coleoptera: Curculionidae) contamination in grain packaging. The anti-insect pest activities of essential oils (EOs) from garlic (Allium Sativum), ginger (Zingiber Officinalis), black pepper (Piper nigrum), onion (Allium cepa), and fennel (Foeniculum vulgare) as well as major compounds (allyl disulfide, AD; allyl mercaptan, AM) isolated from of garlic and onion (AD and AM) were measured against S...
October 14, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29027276/natural-medicines-for-acute-renal-failure-a-review
#4
REVIEW
Motahareh Boozari, Hossein Hosseinzadeh
Acute renal failure (ARF) is a life-threating disease with high mortality percentage. Two important mechanisms of ARF are inflammation and oxidative stress. Plants are rich source of antioxidant compounds and have a strong anti-inflammatory activity, so they may be useful for the treatment of ARF. Some herbal medicines are effective against different models of experimentally induced ARF such as cisplatin, gentamicin, glycerol, and ischemia-reperfusion injury. Some of these plants such as ginseng, black seed, ginger, garlic, grape, pomegranate, saffron, and green tea are so famous and are effective against various models of ARF...
October 13, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29024570/deuterium-reinforced-polyunsaturated-fatty-acids-improve-cognition-in-a-mouse-model-of-sporadic-alzheimer-s-disease
#5
Ahmed Elharram, Nicole M Czegledy, Michael Golod, Ginger L Milne, Erik Pollock, Brian M Bennett, Mikhail S Shchepinov
Oxidative damage resulting from increased lipid peroxidation (LPO) is considered an important factor in the development of late onset/age-related Alzheimer's disease (AD). Deuterium-reinforced polyunsaturated fatty acids (D-PUFAs) are more resistant to the reactive oxygen species-initiated chain reaction of LPO than regular hydrogenated (H-) PUFAs. We investigated the effect of D-PUFA treatment on LPO and cognitive performance in aldehyde dehydrogenase 2 (Aldh2) null mice, an established model of oxidative stress-related cognitive impairment that exhibits AD-like pathologies...
October 12, 2017: FEBS Journal
https://www.readbyqxmd.com/read/29019244/interindividual-variability-in-metabolism-of-6-shogaol-by-gut-microbiota
#6
Pei Wang, Ronghui Wang, Yingdong Zhu, Shengmin Sang
[6]-Shogaol (6S), one of the major bioactive components in dry ginger, is attracting considerable attention because of its wide spectrum of biological activities, but its metabolic fate is still not fully understood. In the present study, the microbial metabolism of 6S was examined for the first time in in vitro batch fecal fermentation system and in mice. Two major microbial metabolites were detected and identified as 1-(4'-hydroxy-3'-methoxyphenyl)-decan-3-ol (M9) and 1-(4'-hydroxy-3'-methoxyphenyl)-decan-3-one (M11)...
October 11, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28992678/alterations-of-food-specific-serum-igg4-titers-to-common-food-antigens-in-patients-with-irritable-bowel-syndrome
#7
Hong Sub Lee, Kwang Jae Lee
Background/Aims: The role of dietary factors in the pathogenesis of irritable bowel syndrome (IBS) is still unclear. The aim of this study was to compare IgG4 levels to common food antigens between patients with IBS and healthy controls. Methods: Thirty-two patients diagnosed as IBS according to the Rome III criteria (12 diarrhea subgroup; 20 non-diarrhea subgroup) and 32 sex and age-matched healthy controls participated in the study. Serum IgG4 titers to 90 common foods were measured in each subject...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28990942/-herbal-supplement-usage-in-cardiac-patients
#8
Neslihan Pınar, Meyli Topaloğlu, Cahit Özer, Harun Alp
OBJECTIVE: Complementary and alternative medicine (CAM) has become more and more widespread around the world. CAM is a broad term that refers to all medical healthcare services, methods, and practices that are not part of standard medical care, as well as the accompanying theories and beliefs. The aim of the present study was to investigate the use of herbal medicinal products in cardiac patients, as well as the methods of administration of the products. METHODS: This descriptive cross-sectional study included 199 patients aged over 18 years who were hospitalized in the Defne Hospital department of cardiology and volunteered to participate in a 20-item survey between April 2016 and June 2016...
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28988478/identification-of-collagen-derived-hydroxyproline-hyp-containing-cyclic-dipeptides-with-high-oral-bioavailability-efficient-formation-of-cyclo-x-hyp-from-x-hyp-gly-type-tripeptides-by-heating
#9
Yuki Taga, Masashi Kusubata, Kiyoko Ogawa-Goto, Shunji Hattori
Cyclic dipeptides (2,5-diketopiperazines) are present in a variety of foods and are reported to demonstrate antioxidant, antidepressant, and other beneficial effects. We recently developed a novel collagen hydrolysate characterized by a high content of X-hydroxyproline (Hyp)-Gly-type tripeptides using ginger protease. In the present study, we found that through heating, X-Hyp-Gly can be easily converted into Hyp-containing cyclic dipeptides. After heating for 3 h at 85°C and pH 4.8, Ala-Hyp-Gly was almost completely cyclized to cyclo(Ala-Hyp) in contrast to a slight cyclization of Ala-Hyp...
October 7, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28974019/a-review-of-the-biomedical-applications-of-zerumbone-and-the-techniques-for-its-extraction-from-ginger-rhizomes
#10
REVIEW
Katayoon Kalantari, Mona Moniri, Amin Boroumand Moghaddam, Raha Abdul Rahim, Arbakariya Bin Ariff, Zahra Izadiyan, Rosfarizan Mohamad
Zerumbone (ZER) is a phytochemical isolated from the subtropical Zingiberaceae family and as a natural compound it has different biomedical properties such as antioxidant, anti-inflammatory anti-proliferative activity. ZER also has effects on angiogenesis and acts as an antitumor drug in the treatment of cancer, showing selective toxicity toward various cancer cell lines. Several techniques also have been established for extraction of ZER from the rhizomes of ginger. This review paper is an overview of recent research about different extraction methods and their efficiencies, in vivo and vitro investigations of ZER and also its prominent chemopreventive properties and treatment mechanisms...
September 30, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28971602/daikenchuto-tu-100-alters-murine-hepatic-and-intestinal-drug-metabolizing-enzymes-in-an-in%C3%A2-vivo-dietary-model-effects-of-gender-and-withdrawal
#11
Kentaro Nobutani, Jun Miyoshi, Mark W Musch, Mitsue Nishiyama, Junko Watanabe, Atsushi Kaneko, Masahiro Yamamoto, Masaru Yoshida, Toru Kono, Hyunyoung Jeong, Eugene B Chang
Herbal medicines and natural products used for maintenance of health or treatment of diseases have many biological effects, including altering the pharmacokinetics and metabolism of other medications. Daikenchuto (TU-100), an aqueous extract of ginger, ginseng, and Japanese green pepper fruit, is a commonly prescribed Kampo (Japanese herbal medicine) for postoperative ileus or bloating. The effects of TU-100 on drug metabolism have not been investigated. In this study, we analyzed the effect of TU-100 on expression of key drug-metabolizing enzymes (DMEs) and drug transporters (DTs) in murine liver and gastrointestinal tract using a dietary model...
October 2017: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28970608/impact-of-student-vs-faculty-facilitators-on-motivational-interviewing-student-outcomes
#12
Rebecca Widder-Prewett, Juanita A Draime, Ginger Cameron, Douglas Anderson, Mark Pinkerton, Aleda M H Chen
Objective. To determine the impact of student or faculty facilitation on student self-assessed attitudes, confidence, and competence in motivational interviewing (MI) skills; actual competence; and evaluation of facilitator performance. Methods. Second-year pharmacy (P2) students were randomly assigned to a student or faculty facilitator for a four-hour, small-group practice of MI skills. MI skills were assessed in a simulated patient encounter with the mMITI (modified Motivational Interviewing Treatment Integrity) tool...
August 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28969549/therapeutic-potential-of-alpinia-officinarum
#13
David Young, Manoharan K Pillai, Mohamed Majid
The plant Alpinia officinarum of the ginger family originated in China and is used throughout South and South-East Asian countries to flavour food and as a traditional medicine to treat a variety of diseases. This review summarizes the biological, pharmacological and phytochemical properties of extracts and subsequently isolated compounds from A. officinarum. In vitro and in vivo studies of both extracts and pure compounds indicate a wide variety of potent bioactivities including anti-inflammatory, antibacterial, antioxidant, antiobesity, anticancer, enzyme inhibitory and remarkable antiviral properties...
October 2, 2017: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/28969119/antimicrobial-activity-of-honey-with-special-reference-to-methicillin-resistant-staphylococcus-aureus-mrsa-and-methicillin-sensitive-staphylococcus-aureus-mssa
#14
Guruvu Neeraja Rani, Radhika Budumuru, Narasinga Rao Bandaru
INTRODUCTION: Antimicrobial agents are essentially important in reducing the global burden of infectious diseases. With the irrational and excessive use of antibiotics in underdeveloped and developing countries, there may be chances to develop and spread resistant pathogens in the community. As a result, the effectiveness of the antibiotics is diminishing. Therefore, the need for novel alternative antimicrobial strategies has renewed interest in natural products like turmeric, honey, ginger and others exhibiting antibacterial properties...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28966452/adrenal-crisis-and-autoimmune-polyglandular-syndromes
#15
Zachary K Freeland, Richard Lueking, Ginger Tsai-Nguyen, Thoris Pan, Adan Mora
We report a 67-year-old woman who presented with adrenal crisis as a manifestation of autoimmune polyglandular syndrome 2, a polygenic disorder characterized by concurrent primary adrenal insufficiency and either autoimmune thyroid disease or type 1 diabetes mellitus.
October 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28963619/the-effect-of-vitamin-e-l-carnitine-and-ginger-on-production-traits-immune-response-and-antioxidant-status-in-two-broiler-strains-exposed-to-chronic-heat-stress
#16
Zia Ur Rehman, Naila Chand, Rifat Ullah Khan
The present study was designed to find the effect of natural and synthetic antioxidants on the performance of two broiler strains under high ambient temperature. A total of 320 day-old chicks of Hubbard and Cobb were reared for a period for 21 days under the same nutritional and management systems. On day 21 onward, one subgroup was kept as control while other subgroups were provided with vitamin E (250 mg/kg), ginger (2 g/kg), and L-carnitine (500 mg/kg) in basal diets. Body weight and feed conversion ratio (FCR) were significantly (P < 0...
September 30, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28961808/oral-delivery-of-nanoparticles-loaded-with-ginger-active-compound-6-shogaol-attenuates-ulcerative-colitis-and-promotes-wound-healing-in-a-murine-model-of-ulcerative-colitis
#17
Mingzhen Zhang, Changlong Xu, Dandan Liu, Moon Kwon Han, Lixin Wang, Didier Merlin
Background and Aims: Oral drug delivery is the most attractive pathway for ulcerative colitis (UC) therapy, since it has many advantages. However, this strategy has encountered many challenges, including the instability of drugs in the gastrointestinal tract (GT), low targeting of disease tissues, and severe adverse effects. Nanoparticles capable of colitis-tissue-targeted delivery and site-specific drug release may offer a unique and therapeutically effective system that addresses these formidable challenges...
August 18, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28961607/planning-and-implementing-immunization-billing-programs-at-state-and-local-health-departments-barriers-and-possible-solutions
#18
Rosemary Corriero, Ginger Redmon
CONTEXT: Before participating in a project funded by the Centers for Disease Control and Prevention, most state and local health departments (LHDs) were not seeking reimbursement or being fully reimbursed by insurance plans for the cost of immunization services (including vaccine costs and administration fees) they provided to insured patients. Centers for Disease Control and Prevention's Billables Project was designed to enable state and LHDs to bill public and private insurance plans for immunization services provided to insured patients...
September 28, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28949009/nausea-and-vomiting-of-pregnancy-effects-on-quality-of-life-and-day-to-day-function
#19
Amelia Tan, Sandra Lowe, Amanda Henry
AIMS: To investigate the effect of nausea and vomiting of pregnancy (NVP) on quality of life (QoL) and activities of daily living/socioeconomic function in a contemporary Australian setting. MATERIALS AND METHODS: Observational, single centre prospective cohort study using validated survey instruments in pregnant women at 9-16 weeks gestation at a tertiary metropolitan women's hospital in Sydney, Australia. QoL measured by the Short-Form Health Survey (SF-12) was compared between those with and without NVP...
September 26, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28947174/trocar-site-hernia-development-in-patients-undergoing-robotically-assisted-or-standard-laparoscopic-staging-surgery-for-endometrial-cancer
#20
Paulina Cybulska, Maria B Schiavone, Brandon Sawyer, Ginger J Gardner, Oliver Zivanovic, Carol L Brown, Elizabeth L Jewell, Yukio Sonoda, Richard R Barakat, Nadeem R Abu-Rustum, Mario M Leitao
OBJECTIVES: To compare the incidence and potential risk factors of trocar site hernia formation in women undergoing robotically assisted versus standard laparoscopic staging (RBT vs. LSC, respectively) for endometrial cancer. METHODS: We retrospectively identified all patients who underwent MIS staging for endometrial cancer at our institution from 01/09-12/12. Data collection involved the review of all operative notes, postoperative follow-up visit notes, and postoperative imaging reports...
September 22, 2017: Gynecologic Oncology
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