keyword
MENU ▼
Read by QxMD icon Read
search

Matera

keyword
https://www.readbyqxmd.com/read/27812097/investigation-of-factors-affecting-aerobic-and-respiratory-growth-in-the-oxygen-tolerant-strain-lactobacillus-casei-n87
#1
Rocco G Ianniello, Teresa Zotta, Attilio Matera, Francesco Genovese, Eugenio Parente, Annamaria Ricciardi
Aerobic and respiratory cultivations provide benefits for some lactic acid bacteria (LAB). Growth, metabolites, enzymatic activities (lactate dehydrogenase; pyruvate and NADH oxidases, NADH peroxidase; catalase), antioxidant capability and stress tolerance of Lactobacillus casei N87 were evaluated in anaerobic, aerobic and respiratory (aerobiosis with heme and menaquinone supplementation) batch cultivations with different dissolved oxygen (DO) concentrations. The expression of pox (pyruvate oxidase) and cydABCD operon (cytochrome bd oxidase complex) was quantified by quantitative Real Time polymerase chain reaction...
2016: PloS One
https://www.readbyqxmd.com/read/27799503/a-case-report-of-schistosoma-haematobium-infection-in-a-pregnant-migrant-raises-concerns-about-lack-of-screening-policies
#2
Maria Mazzitelli, Giovanni Matera, Carmela Votino, Federica Visconti, Alessio Strazzulla, Maria Teresa Loria, Cinzia Peronace, Pio Settembre, Aida Giancotti, Maria Carla Liberto, Alfredo Focà, Fulvio Zullo, Carlo Torti
Pregnant women with urinary schistosomiasis should be treated, but screening is not implemented in migrants. We report herein a case of a migrant diagnosed late into pregnancy, after diagnosis was made in her husband. Praziquantel was safe and effective. Schistosomiasis should be considered in pregnant women from endemic countries.
July 2016: Journal of Travel Medicine
https://www.readbyqxmd.com/read/27791956/17th-international-conference-on-beh%C3%A3-et-s-disease
#3
Ignazio Olivieri
****************************************************************************.
September 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27787709/muscarinic-receptor-antagonists
#4
Maria Gabriella Matera, Mario Cazzola
Parasympathetic activity is increased in patients with chronic obstructive pulmonary disease (COPD) and asthma and appears to be the major reversible component of airway obstruction. Therefore, treatment with muscarinic receptor antagonists is an effective bronchodilator therapy in COPD and also in asthmatic patients. In recent years, the accumulating evidence that the cholinergic system controls not only contraction by airway smooth muscle but also the functions of inflammatory cells and airway epithelial cells has suggested that muscarinic receptor antagonists could exert other effects that may be of clinical relevance when we must treat a patient suffering from COPD or asthma...
October 28, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27783268/fixed-dose-combination-inhalers
#5
Mario Cazzola, Maria Gabriella Matera
In asthma and chronic obstructive pulmonary disease (COPD), an important step in simplifying management and improving adherence with prescribed therapy is to reduce the dose frequency to the minimum necessary to maintain disease control. Fixed-dose combination (FDC) therapy might enhance compliance by decreasing the number of medications and/or the number of daily doses. Furthermore, they have the potential for enhancing, sensitizing, and prolonging the effects of monocomponents. Combination therapy with an inhaled corticosteroid (ICS) and a long-acting β-agonist (LABA) is considered an important approach for treating patients with asthma and patients with severe COPD who have frequent exacerbations...
October 26, 2016: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/27759641/ultrasound-screening-for-neoplasms-in-children-up-to-6-years-old
#6
Grzegorz Jedrzejewski, Magdalena M Wozniak, Agata Pawelec, Albert Matera, Magdalena Kunach, Tomasz Madej, Andrzej P Wieczorek, Katarzyna Nowakowska
The aim of the ultrasound (US) screening program was to detect neoplastic lesions in children, together with other pathologies of the developmental age in the area of the neck, abdomen, female pelvis, and scrotum in boys.US screening scans, including cervical, abdominal, pelvical, and scrotal US, were performed in the population of asymptomatic children aged from 9 months to 6 years. The children were scanned in Mobile Pediatric US Unit, consisting of 2 independent consulting rooms.The scans of 14,324 children were analyzed, 7247 boys and 7077 girls...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27726025/before-the-first-breath-prenatal-exposures-to-air-pollution-and-lung-development
#7
Mariana Matera Veras, Nilmara de Oliveira Alves, Lais Fajersztajn, Paulo Saldiva
Various environmental contaminants are known to impair the growth trajectories of major organs, indirectly (gestational exposure) or directly (postnatal exposure). Evidence associates pre-gestational and gestational exposure to air pollutants with adverse birth outcomes (e.g., low birth weight, prematurity) and with a wide range of diseases in childhood and later in life. In this review, we explore the way that pre-gestational and gestational exposure to air pollution affects lung development. We present results in topics underlining epidemiological and toxicological evidence...
October 10, 2016: Cell and Tissue Research
https://www.readbyqxmd.com/read/27702942/trans-ethnic-meta-analysis-of-genome-wide-association-studies-for-hirschsprung-disease
#8
Clara Sze-Man Tang, Hongsheng Gui, Ashish Kapoor, Jeong-Hyun Kim, Berta Luzón-Toro, Anna Pelet, Grzegorz Burzynski, Francesca Lantieri, Man-Ting So, Courtney Berrios, Hyoung Doo Shin, Raquel M Fernández, Thuy-Linh Le, Joke B G M Verheij, Ivana Matera, Stacey S Cherny, Priyanka Nandakumar, Hyun Sub Cheong, Guillermo Antiñolo, Jeanne Amiel, Jeong-Meen Seo, Dae-Yeon Kim, Jung-Tak Oh, Stanislas Lyonnet, Salud Borrego, Isabella Ceccherini, Robert M W Hofstra, Aravinda Chakravarti, Hyun-Young Kim, Pak Chung Sham, Paul K H Tam, Maria-Mercè Garcia-Barceló
Hirschsprung disease (HSCR) is the most common cause of neonatal intestinal obstruction. It is characterized by the absence of ganglia in the nerve plexuses of the lower gastrointestinal tract. So far, three common disease-susceptibility variants at the RET, SEMA3 and NRG1 loci have been detected through genome-wide association studies (GWAS) in Europeans and Asians to understand its genetic etiologies. Here we present a trans-ethnic meta-analysis of 507 HSCR cases and 1191 controls, combining all published GWAS results on HSCR to fine-map these loci and narrow down the putatively causal variants to 99% credible sets...
October 3, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27697501/deoxycholic-acid-derivatives-as-inhibitors-of-p-glycoprotein-mediated-multidrug-efflux
#9
Luc Rocheblave, Marc Rolland de Ravel, Elodie Monniot, Jeremy Tavenard, Claude-Yves Cuilleron, Catherine Grenot, Sylvie Radix, Eva-Laure Matera, Charles Dumontet, Nadia Walchshofer
Deoxycholic acid derivatives were designed as P-glycoprotein (Pgp, ABCB1) inhibitors. Thus the synthesis and the biological activity of methyl deoxycholate derivatives 5-10 and their ether analogs 15-20 have been reported. The potency of these compounds to modulate Pgp-mediated MDR was evaluated through daunorubicin accumulation and potentiation of doxorubicin cytotoxicity in K562/R7 multidrug resistant cells overexpressing Pgp. In parallel, their intrinsic toxicity was appreciated on K562 sensitive cells. Methyl 12α-[(2R or 2S) tetrahydro-2H-pyran-2-yloxy]-3-oxo-5β-cholan-24-oate 9b has shown a good efficiency as a Pgp inhibitor and a low intrinsic toxicity...
September 30, 2016: Steroids
https://www.readbyqxmd.com/read/27669761/early-effects-of-fluoro-edenite-correlation-between-il-18-serum-levels-and-pleural-and-parenchymal-abnormalities
#10
Caterina Ledda, Carla Loreto, Serena Matera, Nicoletta Massimino, Emanuele Cannizzaro, Andrea Musumeci, Marcello Migliore, Concettina Fenga, Cristoforo Pomara, Venerando Rapisarda
Fluoro-edenite (FE) is a natural mineral asbestos-like fibrous species first isolated in Biancavilla, Sicily. In order to clarify potential involvement of IL-18 in the pathogenesis of FE-induced chest abnormalities, we analyzed IL-18 serum levels in FE-exposed workers (FEEW) and correlated them with pleural and parenchymal abnormalities. A total of 21 FEEWs, residing in Biancavilla for >30 years, with a working seniority of 17 ± 6.1 years were examined. High-resolution computed tomography scans revealed low grade of fibrosis in 8 (38%) FEEWs, and pleural plaques (PPs) in 13 (62%) FEEWs...
September 27, 2016: Future Oncology
https://www.readbyqxmd.com/read/27648855/smn-a-chaperone-for-nuclear-rnp-social-occasions
#11
Amanda C Raimer, Kelsey M Gray, A Gregory Matera
Survival Motor Neuron (SMN) protein localizes to both the nucleus and the cytoplasm. Cytoplasmic SMN is diffusely localized in large oligomeric complexes with core member proteins, called Gemins. Biochemical and cell biological studies have demonstrated that the SMN complex is required for the cytoplasmic assembly and nuclear transport of Sm-class ribonucleoproteins (RNPs). Nuclear SMN accumulates with spliceosomal small nuclear (sn)RNPs in Cajal bodies, sub-domains involved in multiple facets of snRNP maturation...
September 20, 2016: RNA Biology
https://www.readbyqxmd.com/read/27615145/assessing-the-viability-of-long-acting-%C3%AE-2-agonists-in-paediatric-asthma-patients-a-pharmacokinetic-pharmacodynamic-perspective
#12
Maria Gabriella Matera, Barbara Rinaldi, Luigino Calzetta, Mario Cazzola
INTRODUCTION: Long-acting β2-agonists (LABAs) combined with inhaled corticosteroids (ICSs) are still commonly prescribed to asthmatic children. Unfortunately, pediatric LABA use is based primarily on data from adults, despite the fact that children are not simply small adults and the magnitude of changes in dose exposure and/or exposure response may not be solely reflected by differences in body weight. AREAS COVERED: The differences in pharmacokinetics (PK) and pharmacodynamics (PD) of LABAs are described and discussed with reference children and adults...
September 14, 2016: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/27577872/a-critical-examination-of-the-recently-reported-crystal-structures-of-the-human-smn-protein
#13
Manfred S Weiss, Kay Diederichs, Randy J Read, Santosh Panjikar, Gregory D Van Duyne, A Gregory Matera, Utz Fischer, Clemens Grimm
A recent publication by Seng et al. in this journal reports the crystallographic structure of refolded, full-length SMN protein and two disease-relevant derivatives thereof. Here, we would like to suggest that at least two of the structures reported in that study are incorrect. We present evidence that one of the associated crystallographic datasets is derived from a crystal of the bacterial Sm-like protein Hfq and that a second dataset is derived from a crystal of the bacterial Gab protein. Both proteins are frequent contaminants of bacterially overexpressed proteins which might have been co-purified during metal affinity chromatography...
August 29, 2016: Human Molecular Genetics
https://www.readbyqxmd.com/read/27566777/direct-interrogation-of-the-role-of-h3k9-in-metazoan-heterochromatin-function
#14
Taylor J R Penke, Daniel J McKay, Brian D Strahl, A Gregory Matera, Robert J Duronio
A defining feature of heterochromatin is methylation of Lys9 of histone H3 (H3K9me), a binding site for heterochromatin protein 1 (HP1). Although H3K9 methyltransferases and HP1 are necessary for proper heterochromatin structure, the specific contribution of H3K9 to heterochromatin function and animal development is unknown. Using our recently developed platform to engineer histone genes in Drosophila, we generated H3K9R mutant flies, separating the functions of H3K9 and nonhistone substrates of H3K9 methyltransferases...
August 15, 2016: Genes & Development
https://www.readbyqxmd.com/read/27560182/high-and-low-salt-intake-during-pregnancy-impact-on-cardiac-and-renal-structure-in-newborns
#15
Priscila Seravalli, Ivone Braga de Oliveira, Breno Calazans Zago, Isac de Castro, Mariana Matera Veras, Edson Nogueira Alves-Rodrigues, Joel C Heimann
INTRODUCTION: Previous studies from our laboratory demonstrated that dietary salt overload and salt restriction during pregnancy were associated with cardiac and renal structural and/or functional alterations in adult offspring. The present study evaluated renal and cardiac structure and the local renin-angiotensin system in newborns from dams fed high-, normal- or low-salt diets during pregnancy. METHODS: Female Wistar rats were fed low- (LS, 0.15% NaCl), normal- (NS, 1...
2016: PloS One
https://www.readbyqxmd.com/read/27506851/therapeutic-monoclonal-antibodies-for-the-treatment-of-chronic-obstructive-pulmonary-disease
#16
REVIEW
Maria Gabriella Matera, Clive Page, Paola Rogliani, Luigino Calzetta, Mario Cazzola
Chronic obstructive pulmonary disease (COPD) is a disorder characterized by a complex chronic inflammatory response that is largely poorly responsive to treatment with corticosteroids. Consequently, there is a huge need to find effective anti-inflammatory agents for the treatment of patients with this disease. Inhibition of cytokines and chemokines or their receptors using monoclonal antibodies (mAbs) could be a potential strategy to treat the inflammatory component of COPD. In this article, we review the therapeutic potential of some of these mAbs; however, to date there has been little or no therapeutic effect of any mAb directed against cytokines or chemokines in patients with COPD...
September 2016: Drugs
https://www.readbyqxmd.com/read/27492531/the-effect-of-n-acetylcysteine-on-biofilms-implications-for-the-treatment-of-respiratory-tract-infections
#17
REVIEW
Francesco Blasi, Clive Page, Gian Maria Rossolini, Lucia Pallecchi, Maria Gabriella Matera, Paola Rogliani, Mario Cazzola
OBJECTIVES: In airway infections, biofilm formation has been demonstrated to be responsible for both acute and chronic events, and constitutes a genuine challenge in clinical practice. Difficulty in eradicating biofilms with systemic antibiotics has led clinicians to consider the possible role of non-antibiotic therapy. The aim of this review is to examine current evidence for the use of N-acetylcysteine (NAC) in the treatment of biofilm-related respiratory infections. METHODS: Electronic searches of PUBMED up to September 2015 were conducted, searching for 'biofilm', 'respiratory tract infection', 'N-acetylcysteine', 'cystic fibrosis', 'COPD', 'bronchiectasis', 'otitis', and 'bronchitis' in titles and abstracts...
August 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27492525/can-bronchial-asthma-with-an-highly-prevalent-airway-and-systemic-vagal-tone-be-considered-an-independent-asthma-phenotype-possible-role-of-anticholinergics
#18
Gennaro Liccardi, Antonello Salzillo, Luigino Calzetta, Mario Cazzola, Maria Gabriella Matera, Paola Rogliani
Recently, we studied occurrence and role of non-respiratory symptoms (n-RSs) before a worsening of asthma symptoms. Some n-RSs such as anxiety, reflux, heartburn, abdominal pain, which appeared within 3 h before the onset of an asthma attack, are the likely result of an imbalance between sympathetic/parasympathetic systems with an increase in cholinergic tone. Therefore, it is likely that some of these n-RSs induced by the increased cholinergic tone might be present related with specific parasympathetic-associated respiratory symptoms such as those elicited by airway narrowing...
August 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27470682/evaluation-of-adiponectin-profile-in-italian-patients-affected-by-obstructive-sleep-apnea-syndrome
#19
Donato Lacedonia, Ersilia Nigro, Maria Gabriella Matera, Olga Scudiero, Maria Ludovica Monaco, Rita Polito, Giovanna Elisiana Carpagnano, Maria Pia Foschino Barbaro, Gennaro Mazzarella, Andrea Bianco, Aurora Daniele
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder; obesity represents a major risk factor for the development and progression of OSAS although obese patients do not necessarily suffer from OSAS. Adipose tissue communicates with lung in both physiologic and pathologic conditions through the production of adipokines, hormones active in metabolic and inflammatory processes. To explore the extent to which Acrp30 impacts on pathophysiology of OSAS and whether these proteins could be considered as targets for both diagnosis and therapy through enzyme-linked immunosorbent assay, western blotting analysis and fast protein liquid chromatography we have analyzed total levels as well as oligomer distribution in OSAS patients...
October 2016: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27454494/the-new-smartphone-application-for-wrist-rehabilitation
#20
Giuseppe Matera, Chinnakart Boonyasirikool, Raul Saggini, Alessandro Pozzi, Loris Pegoli
BACKGROUND: The rehabilitation after wrist surgery is extremely important. An instructed therapy in hospital is widely practiced. However, a dependent aging society and rush life style in younger generation have precluded patients to access to the frequent formal therapy. With the advancement in telecommunication technology, we have invented an application for smartphone for home-based wrist motion rehabilitation. METHODS: Twenty participants were included in four-week wrist motion rehabilitation programme after wrist surgery...
February 2016: Journal of Hand Surgery Asian-Pacific Volume
keyword
keyword
92323
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"