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https://www.readbyqxmd.com/read/28647971/-association-between-body-fat-percentage-visceral-fat-index-and-cardiometabolic-risk-factor-clustering-among-population-aged-35-year-old-or-over-in-tibet-autonomous-region-and-xinjiang-uygur-autonomous-region
#1
J L Wang, Z Chen, L F Zhang, X Wang, Y Dong, J Y Nie, C Y Zheng, L Shao, Y Tian, Z W Wang
Objective: To investigate the association between body fat percentage (BFP), visceral fat index (VFI) and Cardiometabolic Risk Factor Clustering (CRFC), among population aged 35 or older in Tibet and Xinjiang areas. Methods: Using the stratified multi-stage random sampling method, 7 571 residents aged 35 or above were examined with international standardized examination between 2015 and 2016. Of the eligible 5 643 participants, association of BFP and VFI with CRFC was defined as having two or more of the four risk factors: hypertension, diabetes mellitus, high TG and low HDL-C, at the same time...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647866/coffee-consumption-and-risk-of-renal-cell-carcinoma
#2
Samuel O Antwi, Jeanette E Eckel-Passow, Nancy D Diehl, Daniel J Serie, Kaitlynn M Custer, Michelle L Arnold, Kevin J Wu, John C Cheville, David D Thiel, Bradley C Leibovich, Alexander S Parker
BACKGROUND: Studies have suggested an inverse association between coffee consumption and risk of renal cell carcinoma (RCC); however, data regarding decaffeinated coffee are limited. METHODS: We conducted a case-control study of 669 incident RCC cases and 1,001 frequency-matched controls. Participants completed identical risk factor questionnaires that solicited information about usual coffee consumption habits. The study participants were categorized as non-coffee, caffeinated coffee, decaffeinated coffee, or both caffeinated and decaffeinated coffee drinkers...
June 24, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28646499/the-association-between-oral-hygiene-and-periodontitis-a-systematic-review-and-meta-analysis
#3
REVIEW
Attawood Lertpimonchai, Sasivimol Rattanasiri, Sakda Arj-Ong Vallibhakara, John Attia, Ammarin Thakkinstian
OBJECTIVE: Dental plaque accumulation and inadequate personal oral hygiene (OH) are known major risk factors of periodontitis. Nevertheless, the magnitude of their effects has not yet been the subject of a meta-analysis. MATERIAL AND METHODS: The Medline and Scopus databases were searched up to May 2016. Observational studies were eligible if they assessed associations between OH and periodontitis in adult subjects. A multivariate random-effects meta-analysis was used to pool the effects of fair/poor OH versus good OH on periodontitis across studies...
June 23, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28646407/associations-of-red-and-processed-meat-intake-with-major-molecular-pathological-features-of-colorectal-cancer
#4
Prudence R Carr, Lina Jansen, Stefanie Bienert, Wilfried Roth, Esther Herpel, Matthias Kloor, Hendrik Bläker, Jenny Chang-Claude, Hermann Brenner, Michael Hoffmeister
Red and processed meat is an established risk factor for colorectal cancer (CRC). However, exact mechanisms to explain the associations remain unclear. Few studies have investigated the association with CRC by molecular tumor features, which could provide relevant information on associated molecular pathways. In this population-based case-control study from Germany (DACHS), 2449 cases and 2479 controls provided information on risk factors of CRC and completed a food frequency questionnaire. Multivariable logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CI) for the associations between meat intake and risk of CRC by molecular pathologic features and specific subtypes...
June 23, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28645981/work-related-psychosocial-factors-and-onset-of-metabolic-syndrome-among-workers-a-systematic-review-and-meta-analysis-protocol
#5
Asuka Sakuraya, Kazuhiro Watanabe, Norito Kawakami, Kotaro Imamura, Emiko Ando, Yumi Asai, Hisashi Eguchi, Yuka Kobayashi, Norimitsu Nishida, Hideaki Arima, Akihito Shimazu, Akizumi Tsutsumi
INTRODUCTION: Metabolic syndrome is an important public health target because of its high prevalence worldwide. Work-related psychosocial factors have been identified as determinants of metabolic syndrome components. However, there have been no systematic reviews or meta-analyses conducted to evaluate the relationship between work-related psychosocial factors and metabolic syndrome as an aggregated cluster. The aim of this study is to examine this association from published prospective studies...
June 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645951/effects-of-socioeconomic-factors-on-cardiovascular-related-symptoms-among-residents-in-fukushima-after-the-great-east-japan-earthquake-a-cross-sectional-study-using-data-from-the-fukushima-health-management-survey
#6
Wen Zhang, Tetsuya Ohira, Seiji Yasumura, Masaharu Maeda, Akira Otsuru, Mayumi Harigane, Naoko Horikoshi, Yuriko Suzuki, Hirooki Yabe, Masato Nagai, Hironori Nakano, Mayumi Hirosaki, Mayu Uemura, Hideto Takahashi, Kenji Kamiya, Shunichi Yamashita, Masafumi Abe
OBJECTIVE: To investigate the association between socioeconomic factors and the exacerbation of cardiovascular symptoms among evacuees after the Great East Japan Earthquake. METHODS: A sample of 73 433 individuals was included in the Fukushima Health Management Survey. Self-report questionnaires were used to determine the influence of socioeconomic factors including living arrangements, loss of employment and decreased income on the exacerbation of headache, dizziness, palpitations and shortness of breath...
June 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28645872/two-obesity-susceptibility-loci-in-lyplal1-and-etv5-independently-associated-with-childhood-hypertension-in-chinese-population
#7
Duo Lv, Dan Zhou, Yan Zhang, Shuai Zhang, Yi-Min Zhu
AIMS: Genome-wide association studies have identified novel obesity-associated susceptibility loci. Associations of these variants with childhood obesity have been studied in our previous research. The purpose of this study is to investigate if these loci are associated with hypertension being independent of obesity in Chinese children and adolescents. METHODS: Nineteen candidate SNPs were genotyped using Sequenom MassARRAY platform among Chinese children (N=2954, 514 hypertension and 2440 controls, aged 7-17years)...
June 20, 2017: Gene
https://www.readbyqxmd.com/read/28645271/association-of-stress-depression-and-suicidal-ideation-with-subjective-oral-health-status-and-oral-functions-in-korean-adults-aged-35%C3%A2-years-or-more
#8
Young Sun Kim, Han-Na Kim, Jung-Ha Lee, Se-Yeon Kim, Eun-Joo Jun, Jin-Bom Kim
BACKGROUND: Oral health greatly affects well-being throughout the different stages of life from childhood to late adulthood. Loss of teeth due to poor oral health hinders mastication, leading to poor nutrition absorption, and affects pronunciation and aesthetics, leading to interpersonal difficulties. As social activities become limited, a sense of isolation and loneliness, stress, and depression grows while happiness decreases. This study aimed to examine the association of stress, depression, and suicidal ideation with oral health status and oral functions in a large nationwide sample of Korean adults aged 35 years or more...
June 23, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28644139/gstp1-polymorphism-predicts-treatment-outcome-and-toxicities-for-breast-cancer
#9
Jie Ma, Shao-Liang Zhu, Yang Liu, Xiang-Yang Huang, Dan-Ke Su
This study aimed to investigate the association of the GSTP1 gene polymorphism with the outcomes and toxicities of treatments in breast cancer. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated for the association of GSTP1 polymorphism with tumour response and toxicities, and the hazard ratios (HRs) and 95% CIs were calculated for the association between GSTP1 polymorphism and overall survival (OS). The statistical analysis showed that the GSTP1 polymorphism was not associated with tumour response or OS...
June 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28644130/mmp-3-gene-polymorphisms-are-associated-with-increased-risk-of-osteoarthritis-in-chinese-men
#10
Wen Guo, Pengcheng Xu, Tianbo Jin, Jihong Wang, Dongsheng Fan, Zengtao Hao, Yuntao Ji, Shangfei Jing, Chaoqian Han, Jieli Du, Dong Jiang, Shuzheng Wen, Jianzhong Wang
Osteoarthritis (OA) is the most common late-onset degenerative joint disease., It is characterized by progressive degradation of articular cartilage. We investigated the association between OA occurrence and single nucleotide polymorphisms (SNPs) in the matrix metalloproteinase-3 (MMP-3)gene involved in the breakdown of extra-cellular matrix proteins. The study included 100 male OA patients and 197 healthy men from the north area of China. Eight MMP-3 SNPs were genotyped. Odds ratios (ORs) with 95% confidence intervals (95%CIs) and multivariate logistic regression analysis were used to assess the association...
June 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28642883/genetic-polymorphisms-of-cytotoxic-t-lymphocyte-antigen-4-in-primary-biliary-cholangitis-a-meta-analysis
#11
REVIEW
Xing-Chen Yang, Masayuki Fujino, Song-Jie Cai, Shao-Wei Li, Chi Liu, Xiao-Kang Li
BACKGROUND AND AIM: The connection between gene polymorphisms of cytotoxic T-lymphocyte-associated protein 4 (CTLA4) and primary biliary cholangitis (PBC) is still vague and blurred. The purpose of this study is to precisely estimate the association of the polymorphisms of CTLA4 with the risk of PBC by using a meta-analysis. METHODS: PubMed and the Chinese National Knowledge Infrastructure (CNKI) database were used to search correlative literatures, and the documents which were about the relationships between the polymorphisms of CTLA4 (rs231775, rs231725, rs3087243, and rs5742909) and PBC were collected as of June 2016...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28642231/secondhand-smoke-exposure-among-community-dwelling-adult-cancer-survivors-in-the-united-states-1999-2012
#12
Oladimeji Akinboro, Odunayo Olorunfemi, Prasanta Basak, Elizabeth Phillips, Daniel Pomerantz, Bernard Bernhardt, Rasim Gucalp, Stephen Jesmajian, Jamie S Ostroff
Background: Little is known about the prevalence of secondhand smoke exposure (SHSe) among cancer survivors. We sought to determine the prevalence, trends, and correlates of SHSe among nonsmoking adult cancer survivors in the United States.Methods: Interview and serum cotinine data for nonsmoking adults, age 20 years and older, with a history of cancer (N = 686) were obtained from consecutive two-year cross-sectional cycles of the National Health and Nutrition Examination Survey from 1999 to 2012. SHSe was defined as serum cotinine 0...
June 22, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28641875/prevention-of-incisional-hernia-with-prophylactic-onlay-and-sublay-mesh-reinforcement-versus-primary-suture-only-in-midline-laparotomies-prima-2-year-follow-up-of-a-multicentre-double-blind-randomised-controlled-trial
#13
An P Jairam, Lucas Timmermans, Hasan H Eker, Robert E G J M Pierik, David van Klaveren, Ewout W Steyerberg, Reinier Timman, Arie C van der Ham, Imro Dawson, Jan A Charbon, Christoph Schuhmacher, André Mihaljevic, Jakob R Izbicki, Panagiotis Fikatas, Philip Knebel, René H Fortelny, Gert-Jan Kleinrensink, Johan F Lange, Hans J Jeekel
BACKGROUND: Incisional hernia is a frequent long-term complication after abdominal surgery, with a prevalence greater than 30% in high-risk groups. The aim of the PRIMA trial was to evaluate the effectiveness of mesh reinforcement in high-risk patients, to prevent incisional hernia. METHODS: We did a multicentre, double-blind, randomised controlled trial at 11 hospitals in Austria, Germany, and the Netherlands. We included patients aged 18 years or older who were undergoing elective midline laparotomy and had either an abdominal aortic aneurysm or a body-mass index (BMI) of 27 kg/m(2) or higher...
June 19, 2017: Lancet
https://www.readbyqxmd.com/read/28641703/a-randomised-controlled-trial-to-assess-the-cost-effectiveness-of-intensive-versus-no-scheduled-follow-up-in-patients-who-have-undergone-resection-for-colorectal-cancer-with-curative-intent
#14
David Mant, Alastair Gray, Siân Pugh, Helen Campbell, Stephen George, Alice Fuller, Bethany Shinkins, Andrea Corkhill, Jane Mellor, Elizabeth Dixon, Louisa Little, Rafael Perera-Salazar, John Primrose
BACKGROUND: Intensive follow-up after surgery for colorectal cancer is common practice but lacks a firm evidence base. OBJECTIVE: To assess whether or not augmenting symptomatic follow-up in primary care with two intensive methods of follow-up [monitoring of blood carcinoembryonic antigen (CEA) levels and scheduled imaging] is effective and cost-effective in detecting the recurrence of colorectal cancer treatable surgically with curative intent. DESIGN: Randomised controlled open-label trial...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28640651/association-of-the-lipoprotein-lipase-gene-ser447ter-polymorphism-with-hypertension-and-blood-pressure-variation-evidence-from-an-updated-meta-analysis
#15
June Wang, Shenlin Du, Jiamin Wang, Man Zhu, Xue Wen, Weiqing Yang
The polymorphism of lipoprotein lipase (LPL) gene Ser447Ter (S447X) has long been linked to hypertension and blood pressure variation, but the established data remained controversial. To better elucidate this inconsistency, a meta-analysis was conducted. We comprehensively searched electronic databases, including Pubmed, EMBASE, China National Knowledge Infrastructure (CNKI), Web of Science, for all literatures with the last update on February 2016. The strength of association was calculated by using odds ratios (ORs) and weighted mean differences (WMDs) with corresponding 95% confidence intervals (CIs)...
June 22, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28640167/timing-of-first-childbirth-and-age-related-cataract
#16
Sangshin Park, Nam-Kyong Choi
OBJECTIVE: No studies investigated the effects of age at first childbirth on cataract formation. This study was performed to determine the relationships of age at first childbirth to age-related cataract in postmenopausal women. METHODS: Study population included 7,021 postmenopausal women in the Korea National Health and Nutrition Examination Survey, 2008 to 2012. Participants were subdivided in quartiles according to the age at first childbirth as follows: 13 to 21, 22 to 23, 24 to 25, and 26 to 44 years...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640128/association-between-polymorphic-cag-repeat-lengths-in-the-androgen-receptor-gene-and-susceptibility-to-prostate-cancer-a-systematic-review-and-meta-analysis
#17
Zhiqiang Qin, Xiao Li, Peng Han, Yuxiao Zheng, Hanyu Liu, Jingyuan Tang, Chengdi Yang, Jianzhong Zhang, Kunpeng Wang, Xiaokang Qi, Min Tang, Wei Wang, Wei Zhang
BACKGROUND: Previous studies have been conducted to reveal the relationship between androgen receptor CAG polymorphism and risk of prostate cancer, yet the results were elusive and controversial. Thus, this meta-analysis was performed to clarify this association. METHODS: To obtain the relevant available studies, online databases PubMed, Embase, and Web of science were searched until September 1st, 2016. The pooled odds ratios (ORs) with 95% confidence intervals (CIs) were used to assess the strength of such association...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28640127/association-between-kcne1-g38s-gene-polymorphism-and-risk-of-atrial-fibrillation-a-prisma-compliant-meta-analysis
#18
Yu-Feng Jiang, Min Chen, Nan-Nan Zhang, Hua-Jia Yang, Lang-Biao Xu, Qing Rui, Si-Jia Sun, Jia-Lu Yao, Ya-Feng Zhou
BACKGROUND: Previous case-control studies on association between KCNE1 G38S polymorphism and risk of atrial fibrillation (AF) have been published but because of the conflicting results and small sample size of individual studies, the consolidated result is still controversial. OBJECTIVES: The aim of this study was to explore the relationship between KCNE1 G38S polymorphism and risk of AF. METHODS: We performed a comprehensive literature search on PubMed, Embase, OVID, Web of Science, Wan Fang, and CNKI databases up to March 10, 2017 in English and Chinese languages...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28639237/work-home-interference-perceived-total-workload-and-the-risk-of-future-sickness-absence-due-to-stress-related-mental-diagnoses-among-women-and-men-a-prospective-twin-study
#19
Pia Svedberg, Lisa Mather, Gunnar Bergström, Petra Lindfors, Victoria Blom
PURPOSE: Work-home interference has been proposed as an important explanation for sickness absence (SA). Previous studies show mixed results, have not accounted for familial factors (genetics and shared everyday environment), or investigated diagnosis specific SA. The aim was to study whether work-home interference and perceived total workload predict SA due to stress-related mental diagnoses, or SA due to other mental diagnoses, among women and men, when adjusting for various confounders and familial factors...
June 21, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28639164/lipid-peroxidation-in-gram-negative-bacteremia-modulates-the-risk-for-septic-shock-and-infections-by-resistant-klebsiella-pneumoniae
#20
S Christodoulou, E Kyriazopoulou, M Chrysanthakopoulou, G Karlis, I Karampela, K Gkizeli, N Veliki, A Safarika, E J Giamarellos-Bourboulis, G Adamis
Controversies in outcomes with the parenteral administration of antioxidants as adjuvant therapies led to the measurement of malondialdehyde (MDA), a product of lipid peroxidation, in serum collected from 120 patients with primary Gram-negative bacteremia during the first 24 h from sepsis onset. MDA was measured by the thiobarbiturate assay, followed by high-performance liquid chromatography (HPLC) analysis. After receiver operator characteristic (ROC) curve analysis, patients were divided into those with high levels of MDA and low levels of MDA...
June 21, 2017: European Journal of Clinical Microbiology & Infectious Diseases
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