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https://www.readbyqxmd.com/read/28535361/maternal-smoking-during-pregnancy-is-associated-with-offspring-hypodontia
#1
A H Al-Ani, J S Antoun, W M Thomson, T R Merriman, M Farella
Little is known about environmental risk factors for hypodontia. The objective of this study was to investigate the association between hypodontia and common environmental risk factors, such as maternal smoking and alcohol and caffeine consumption during pregnancy. Eighty-three hypodontia cases with 1 or more missing permanent lateral incisors and/or 1 or more missing premolars were enrolled in this clinic-based case-control study. Some 253 controls with no missing teeth were frequency matched to cases by age and sex...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28534597/metabolomics-for-improving-pregnancy-outcomes-in-women-undergoing-assisted-reproductive-technologies
#2
REVIEW
Charalampos S Siristatidis, Eleni Sertedaki, Dennis Vaidakis
BACKGROUND: In order to overcome the low effectiveness of assisted reproductive technologies (ART) and the high incidence of multiple births, metabolomics is proposed as a non-invasive method to assess oocyte quality, embryo viability, and endometrial receptivity, and facilitate a targeted subfertility treatment. OBJECTIVES: To evaluate the effectiveness and safety of metabolomic assessment of oocyte quality, embryo viability, and endometrial receptivity for improving live birth or ongoing pregnancy rates in women undergoing ART, compared to conventional methods of assessment...
May 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28534012/association-of-isolated-single-umbilical-artery-with-perinatal-outcomes-systemic-review-and-meta-analysis
#3
Hyeong Ju Kim, Jae-Hoon Kim, Doo Byung Chay, Joo Hyun Park, Min-A Kim
OBJECTIVE: The aim of this study was to evaluate the association between prenatally diagnosed isolated single umbilical artery (iSUA) and perinatal outcomes. METHODS: We searched Medline, Embase, the Cochrane Library, and KoreaMed from inception to January 2016, with no language or regional restrictions, for cohort and case-control studies reporting on the relationship of iSUA and perinatal outcomes. We assessed the odds ratios (ORs) and 95% confidence intervals (CIs) for the occurrence of small for gestational age, preterm birth, pregnancy-induced hypertension, neonatal intensive care unit admission, and perinatal mortality in fetuses with iSUA compared with those in fetuses with three vessel cord...
May 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28533506/the-correlation-theory-of-the-chemical-bond
#4
Szilárd Szalay, Gergely Barcza, Tibor Szilvási, Libor Veis, Örs Legeza
The quantum mechanical description of the chemical bond is generally given in terms of delocalized bonding orbitals, or, alternatively, in terms of correlations of occupations of localised orbitals. However, in the latter case, multiorbital correlations were treated only in terms of two-orbital correlations, although the structure of multiorbital correlations is far richer; and, in the case of bonds established by more than two electrons, multiorbital correlations represent a more natural point of view. Here, for the first time, we introduce the true multiorbital correlation theory, consisting of a framework for handling the structure of multiorbital correlations, a toolbox of true multiorbital correlation measures, and the formulation of the multiorbital correlation clustering, together with an algorithm for obtaining that...
May 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28533426/a-reappraised-meta-analysis-of-the-genetic-association-between-vitamin-d-receptor-bsm-i-rs1544410-polymorphism-and-pulmonary-tuberculosis-risk
#5
Mohammed Y Areeshi, Raju K Mandal, Sajad Ahmad Dar, Abdulrahman M Alshahrani, Aqeel Ahmad, Arshad Jawed, Mohd Wahid, Mohtashim Lohani, Aditya K Panda, Shafiul Haque
BsmI (rs1544410) polymorphism located in intron 8 at the 3' end of the VDR gene is known to be involved in the regulation of mRNA stability. Many studies evaluated the possible correlation between VDR Bsm I polymorphism and the risk of pulmonary tuberculosis (PTB), and reported conflicting results. In this study, an updated meta-analysis was performed to evaluate the above said association. PubMed, EMBASE, and Google Scholar web-databases were searched for the relevant studies and a meta-analysis was performed by calculating pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) for all the genetic models...
May 22, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28533189/potential-therapeutic-effects-of-odorants-through-their-ectopic-receptors-in-pigmented-cells
#6
REVIEW
Barbara Pavan, Antonio Capuzzo, Alessandro Dalpiaz
Several olfactory receptors (ORs) have been characterized outside the olfactory neuroepithelium in neuronal and non-neuronal tissues, where they were implicated in the recognition of diverse chemical signals. ORs have been found to regulate melanogenesis in skin melanocytes, and OR expression has been found in the human brain nigrostriatal dopaminergic neurons, where production of melanin occurs as neuromelanin and can change with age; OR expression is downregulated in Parkinson's disease. Therefore, we propose several odorants as new functional ligands to ORs expressed in non-olfactory pigmented cells as dopaminergic neurons and melanocytes, where, by acting on cAMP-induced melanin production, they could help to counteract melanogenic and neurodegenerative dysfunctions, including melanoma and Parkinson's disease...
May 19, 2017: Drug Discovery Today
https://www.readbyqxmd.com/read/28532413/dietary-habits-oral-impact-on-daily-performance-and-type-2-diabetes-a-matched-case-control-study-from-sudan
#7
Hasaan G Mohamed, Kamal Mustafa, Salah O Ibrahim, Anne N Åstrøm
BACKGROUND: It is evident that social and behavioural factors influence on individuals' general health and quality of life. Nevertheless, information about the influence of dietary habits on oral health-related quality of life is limited; especially among patients with type 2 diabetes (T2D). The aim of this study was to examine the influence of dietary habits and clinical oral health indicators on oral health-related quality of life in individuals with and without T2D. METHODS: A total of 149 T2D cases and 298 controls were recruited for this age and gender matched case-control study...
May 22, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28532261/abo-blood-types-and-postpartum-depression-among-chinese-women-a-prospective-cohort-study-in-tianjin-china
#8
Chunhua Song, Junhong Leng, Leishen Wang, Wei Li, Shuang Zhang, Wei Wang, Pingying Liu, Jing Zhang, Bin Xie, Weidong Li, Juliana Cn Chan, Xilin Yang
Postpartum depression is associated with adverse consequences for mother and offspring. The heritable ABO blood group has been associated with multiple diseases, including mental illness and diabetes. We explored the association of ABO blood group and postpartum depressive symptoms (PPDS) in a population-based cohort of pregnant Chinese women. From 2010 to August 2012, we recruited 8842 pregnant women with a mean age of 28.5 years (SD: 2.94) and mean body mass index of 22.4kg/m(2) (SD: 3.45) in Tianjin, China...
May 22, 2017: Women & Health
https://www.readbyqxmd.com/read/28529617/combined-detection-of-plasma-zic1-hoxd10-and-runx3-methylation-is-a-promising-strategy-for-early-detection-of-gastric-cancer-and-precancerous-lesions
#9
Zhenghua Lin, Mengzhao Luo, Xueqing Chen, Xingkang He, Yun Qian, Sanchuan Lai, Jianmin Si, Shujie Chen
We try to explore the value of aberrant DNA methylation of several cancer-related genes in plasma as non-invasive biomarkers for gastric cancer (GC) and precancerous lesions. By using methylation-specific polymerase chain reaction assay we determined the methylation status of three selected genes ZIC1, HOXD10 and RUNX3 in blood samples from patients with GC and precancerous lesions. We discovered that the methylation rate of ZIC1, HOXD10 and RUNX3 increased significantly in the progression of gastric carcinogenesis...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28527931/predictors-of-surgical-site-infection-after-open-lower-extremity-revascularization
#10
Frank M Davis, Danielle C Sutzko, Scott F Grey, M Ashraf Mansour, Krishna M Jain, Timothy J Nypaver, Greg Gaborek, Peter K Henke
OBJECTIVE: Surgical site infection (SSI) after open lower extremity bypass (LEB) is a serious complication leading to an increased rate of graft failure, hospital readmission, and health care costs. This study sought to identify predictors of SSI after LEB for arterial occlusive disease and also potential modifiable factors to improve outcomes. METHODS: Data from a statewide cardiovascular consortium of 35 hospitals were used to obtain demographic, procedural, and hospital risk factors for patients undergoing elective or urgent open LEB between January 2012 and June 2015...
June 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28527006/analysis-of-surgical-and-mri-factors-associated-with-cerebellar-mutism
#11
Anjali Sergeant, Michelle Masayo Kameda-Smith, Branavan Manoranjan, Brij Karmur, JoAnn Duckworth, Tina Petrelli, Katey Savage, Olufemi Ajani, Blake Yarascavitch, M Constantine Samaan, Katrin Scheinemann, Cheryl Alyman, Saleh Almenawer, Forough Farrokhyar, Adam J Fleming, Sheila Kumari Singh, Nina Stein
The surgical risk factors and neuro-imaging characteristics associated with cerebellar mutism (CM) remain unclear and require further investigation. Therefore, we aimed to examine surgical and MRI findings associated with CM in children following posterior fossa tumor resection. Using our data registry, we retrospectively collected data from pediatric patients who acquired CM and were matched based on age and pathology type with individuals who did not acquire CM after posterior fossa surgery. The strength of association between surgical and MRI variables and CM were examined using odds ratios (ORs) and corresponding 95% confidence intervals (CIs)...
May 19, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28526222/hemocytometric-measures-predict-the-efficacy-of-oral-rehydration-for-children-with-postural-tachycardia-syndrome
#12
Wenxin Lu, Hui Yan, Shu Wu, Wenrui Xu, Hongfang Jin, Junbao Du
OBJECTIVE: To explore whether hemocytometric measures could be qualified predictors for the effect of oral rehydration salts (ORS) in children with postural tachycardia syndrome (POTS). STUDY DESIGN: Thirty-five children with POTS and 29 healthy children were enrolled. General information, hemodynamic status, and baseline hemocytometric variables were collected. Children with POTS received ORS therapy and were followed up for 3 months. The independent risk factors of developing POTS were explored...
May 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28525637/characterizing-adult-sleep-behavior-over-20-years-the-population-based-doetinchem-cohort-study
#13
Margot L Zomers, Gerben Hulsegge, Sandra H van Oostrom, Karin I Proper, Wm Monique Verschuren, H Susan J Picavet
Study Objectives: To describe sleep duration patterns of adults over a 20-year period, to compare sociodemographic, lifestyle, and health characteristics across these patterns, and to relate the patterns to sleep quality. Methods: The study population consisted of 3,695 adults aged 20 to 59 years at baseline. Five measurements of self-reported sleep duration were used to compose seven patterns from 1987 to 2012: persistent short (≤6 hours), moderate (7-8 hours), or long (≥9 hours) sleep duration and several changing patterns (varying and became short, moderate, or long sleepers)...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28525629/the-association-of-perceived-memory-loss-with-osteoarthritis-and-related-joint-pain-in-a-large-appalachian-population
#14
Kim E Innes, Usha Sambamoorthi
Objective. : Previous studies have documented memory impairment in several chronic pain syndromes. However, the potential link between memory loss and osteoarthritis (OA), the second most common cause of chronic pain, remains little explored. In this cross-sectional study, we examine the association of perceived memory loss to OA and assess the potential mediating influence of sleep and mood disturbance in a large Appalachian population. Design.:  Cross-sectional...
May 19, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28525511/factors-affecting-acoustics-and-speech-intelligibility-in-the-operating-room-size-matters
#15
Richard R McNeer, Christopher L Bennett, Danielle Bodzin Horn, Roman Dudaryk
INTRODUCTION: Noise in health care settings has increased since 1960 and represents a significant source of dissatisfaction among staff and patients and risk to patient safety. Operating rooms (ORs) in which effective communication is crucial are particularly noisy. Speech intelligibility is impacted by noise, room architecture, and acoustics. For example, sound reverberation time (RT60) increases with room size, which can negatively impact intelligibility, while room objects are hypothesized to have the opposite effect...
June 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28524093/protective-effect-of-dietary-calcium-intake-on-esophageal-cancer-risk-a-meta-analysis-of-observational-studies
#16
Qianwen Li, Lingling Cui, Yalan Tian, Han Cui, Li Li, Weifeng Dou, Haixia Li, Ling Wang
Although several epidemiological studies have investigated the association between dietary calcium intake and the risk of esophageal cancer, the results are inconsistent. This study aimed to make a comprehensive evaluation regarding the association between calcium intake and risk of esophageal cancer through a meta-analysis approach. We searched for all relevant articles from the inception to April 2017, using PUBMED, EMBASE, and Web of Knowledge. The pooled odds ratio (ORs) with the 95% confidence interval (95% CI) for the highest versus the lowest categories of calcium intake was calculated using a Mantel-Haenszel fixed-effect model...
May 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28522877/dce-mri-background-parenchymal-enhancement-quantified-from-an-early-versus-delayed-post-contrast-sequence-association-with-breast-cancer-presence
#17
Shandong Wu, Margarita L Zuley, Wendie A Berg, Brenda F Kurland, Rachel C Jankowitz, Jules H Sumkin, David Gur
We investigated automated quantitative measures of background parenchymal enhancement (BPE) derived from an early versus delayed post-contrast sequence in breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for association with breast cancer presence in a case-control study. DCE-MRIs were retrospectively analyzed for 51 cancer cases and 51 controls with biopsy-proven benign lesions, matched by age and year-of-MRI. BPE was quantified using fully-automated validated computer algorithms, separately from three sequential DCE-MRI post-contrast-subtracted sequences (SUB1, SUB2, and SUB3)...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28521294/expression-of-glucose-transporter-1-and-prognosis-in-non-small-cell-lung-cancer-a-pooled-analysis-of-1665-patients
#18
Zhibo Tan, Chao Yang, Xiaohan Zhang, Pingju Zheng, Weixi Shen
Glucose transporter 1 (GLUT1) plays an important role in the transport and metabolism of glucose in cancer cells. An increasing number of studies have explored the connection between GLUT1 expression and prognosis in non-small cell lung cancer (NSCLC), but the results have been controversial. Therefore, we conducted a meta-analysis to obtain a comprehensive evaluation of the prognostic value of GLUT1 in NSCLC. Relevant studies from PubMed, Embase, and Web of Science were searched. Hazard ratios (HRs) and odds ratios (ORs) with their 95% confidence intervals (CIs) were used as the effective measures...
May 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28520645/oxidative-stress-and-breast-cancer-risk-in-premenopausal-women
#19
Hazel B Nichols, Chelsea Anderson, Alexandra J White, Ginger L Milne, Dale P Sandler
BACKGROUND: Detrimental effects of oxidative stress are widely recognized, but induction of apoptosis and senescence may also have benefits for cancer prevention. Recent studies suggest oxidative stress may be associated with lower breast cancer risk before menopause. METHODS: We conducted a nested case-control study (N=457 cases, 910 controls) within the NIEHS Sister Study cohort of 50,884 women. Premenopausal women ages 35-54 were eligible for selection. We matched controls 2:1 to cases on age and enrollment year and were breast cancer-free at the time of the corresponding case's diagnosis...
May 17, 2017: Epidemiology
https://www.readbyqxmd.com/read/28515515/the-parturient-in-the-interventional-radiology-suite-new-frontier-in-obstetric-anaesthesia
#20
REVIEW
Tasneem Dhansura, Nabila Shaikh
The anaesthesiologist's presence during interventional radiology (IR) is increasing due to increasingly ill patients and intricate procedures. The management of a parturient in IR suite is complex in terms of logistics of an unfamiliar procedure in an unfamiliar area. The literature available is largely written by radiologists with little attention paid to anaesthetic details and considerations. In the Indian scenario, in the absence of hybrid operating rooms (ORs), logistics involve transport of a parturient back and forth between the IR suite and the OR...
April 2017: Indian Journal of Anaesthesia
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