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https://www.readbyqxmd.com/read/29791315/incidence-of-early-onset-sepsis-in-infants-born-to-women-with-clinical-chorioamnionitis
#1
Tara M Randis, Madeline Murguia Rice, Leslie Myatt, Alan T N Tita, Kenneth J Leveno, Uma M Reddy, Michael W Varner, John M Thorp, Brian M Mercer, Mara J Dinsmoor, Susan M Ramin, Marshall W Carpenter, Philip Samuels, Anthony Sciscione, Jorge E Tolosa, George Saade, Yoram Sorokin
OBJECTIVE: To determine the frequency of sepsis and other adverse neonatal outcomes in women with a clinical diagnosis of chorioamnionitis. METHODS: We performed a secondary analysis of a multi-center placebo-controlled trial of vitamins C/E to prevent preeclampsia in low risk nulliparous women. Clinical chorioamnionitis was defined as either the "clinical diagnosis" of chorioamnionitis or antibiotic administration during labor because of an elevated temperature or uterine tenderness in the absence of another cause...
May 23, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29789351/development-and-validation-of-two-clinical-prediction-models-to-inform-clinical-decision-making-for-lumbar-spinal-fusion-surgery-for-degenerative-disorders-and-rehabilitation-following-surgery-protocol-for-a-prospective-observational-study
#2
Alison B Rushton, Martin L Verra, Andrew Emms, Nicola R Heneghan, Deborah Falla, Michael Reddington, Ashley A Cole, Paul Willems, Lorin Benneker, David Selvey, Michael Hutton, Martijn W Heymans, J Bart Staal
INTRODUCTION: Potential predictors of poor outcome will be measured at baseline: (1) preoperatively to develop a clinical prediction model to predict which patients are likely to have favourable outcome following lumbar spinal fusion surgery (LSFS) and (2) postoperatively to predict which patients are likely to have favourable long-term outcomes (to inform rehabilitation). METHODS AND ANALYSIS: Prospective observational study with a defined episode inception of the point of surgery...
May 22, 2018: BMJ Open
https://www.readbyqxmd.com/read/29788820/injury-and-infection-in-dental-clinics-risk-factors-and-prevention
#3
Mustafa Al-Zoughool, Zaina Al-Shehri
Needlestick and sharp instrument injuries are common in dental practice and present the risk of direct exposure to blood-borne pathogens, including hepatitis B virus. This cross-sectional study was carried out to determine the risk factors of injury and infection in three types of dental clinic in Riyadh, Saudi Arabia. A total of 274 male and 241 female dentists completed a structured questionnaire on demographic factors, compliance with infection control practices, and past exposure to injury and infection hazards...
January 1, 2018: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29788477/the-relationship-between-sociodemographic-factors-and-reporting-having-terminated-a-pregnancy-among-ghanaian-women-a-population-based-study
#4
Emmanuel Dankwah, Megan Steeves, Dana Ramsay, Cindy Feng, Marwa Farag
Background: Pregnancy termination is an illegal medical procedure in Ghana and 88% of induced abortions are performed in unsafe conditions, thus recipients face an elevated risk of abortion-related complications. This study aims to explore the associations between sociodemographic factors and reporting having terminated a pregnancy among Ghanaian women. Methods: Logistic regression models were estimated using data from the 2014 Ghana Demographic and Health Survey (n=9396)...
May 19, 2018: International Health
https://www.readbyqxmd.com/read/29788475/associations-between-prediagnostic-concentrations-of-circulating-sex-steroid-hormones-and-esophageal-gastric-cardia-adenocarcinoma-among-men
#5
Jessica L Petrick, Paula L Hyland, Patrick Caron, Roni T Falk, Ruth M Pfeiffer, Sanford M Dawsey, Christian C Abnet, Philip R Taylor, Stephanie J Weinstein, Demetrius Albanes, Neal D Freedman, Susan M Gapstur, Gary Bradwin, Chantal Guillemette, Peter T Campbell, Michael B Cook
Background: Esophageal adenocarcinoma (EA) and gastric cardia adenocarcinoma (GCA) are characterized by a strong male predominance. Concentrations of sex steroid hormones have been hypothesized to explain this sex disparity. However, no prospective population-based study has examined sex steroid hormones in relation to EA/GCA risk. Thus, we investigated whether prediagnostic circulating sex steroid hormone concentrations were associated with EA/GCA in a nested case-control study drawn from participants in three prospective cohort studies...
May 17, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29787929/association-between-the-ratio-of-serum-arachidonic-acid-to-eicosapentaenoic-acid-and-the-presence-of-depressive-symptoms-in-a-general-japanese-population-the-hisayama-study
#6
Mao Shibata, Tomoyuki Ohara, Daigo Yoshida, Jun Hata, Naoko Mukai, Hiroyuki Kawano, Shigenobu Kanba, Takanari Kitazono, Toshiharu Ninomiya
BACKGROUND: Epidemiological evidence suggests that fish consumption and intake of n-3 polyunsaturated fatty acids (PUFA)-namely, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)-confer protection against depression. However, few studies have addressed the influence of the balance between n-3 PUFA and n-6 PUFA in the human body on depression. METHODS: A total of 2,529 community-dwelling Japanese residents aged ≥ 40 years were assessed for depressive symptoms (defined as a score of 16 points or more on the Center for Epidemiologic Studies Depression Scale [CES-D]) in 2007...
May 14, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29787920/identification-and-characterization-of-chemosensory-genes-in-the-antennal-transcriptome-of-spodoptera-exigua
#7
Li-Xiao Du, Yang Liu, Jin Zhang, Xi-Wu Gao, Bing Wang, Gui-Rong Wang
Chemical senses are crucial for insect behaviors such as host preference, mate choice and oviposition site selection. Various protein families are involved in these processes, including odorant receptors (ORs), ionotropic receptors (IRs), gustatory receptors (GRs), chemosensory proteins (CSPs), odorant binding proteins (OBPs) and sensory neuron membrane proteins (SNMPs). To better understand the olfactory mechanism in Spodoptera exigua, we conducted transcriptome analysis of adult antennae and identified a total of 157 candidate chemosensory genes encoding 51 ORs, 20 IRs, 7 GRs, 32 CSPs, 45 OBPs and 2 SNMPs...
May 7, 2018: Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics
https://www.readbyqxmd.com/read/29787898/long-term-effects-of-air-pollution-on-ankle-brachial-index
#8
Siqi Zhang, Kathrin Wolf, Susanne Breitner, Florian Kronenberg, Massimo Stafoggia, Annette Peters, Alexandra Schneider
BACKGROUND: Ankle-brachial index (ABI) has been linked to the risk of cardiovascular events. However, the association between long-term exposure to air pollution and abnormal ABI has not been fully investigated. METHODS: This cross-sectional study involved 4544 participants from the KORA Study (2004-2008) in the region of Augsburg, Germany. Participants' residential annual mean concentrations of particulate matter (PM) and nitrogen dioxide (NO2 ) were predicted with land-use regression models, and the traffic information was collected from geographic information systems...
May 19, 2018: Environment International
https://www.readbyqxmd.com/read/29787477/metabolic-syndrome-and-its-components-in-premenopausal-and-postmenopausal-women-a-comprehensive-systematic-review-and-meta-analysis-on-observational-studies
#9
Jamal Hallajzadeh, Maliheh Khoramdad, Neda Izadi, Nahid Karamzad, Amir Almasi-Hashiani, Erfan Ayubi, Mostafa Qorbani, Reza Pakzad, Amir Hasanzadeh, Mark J M Sullman, Saeid Safiri
OBJECTIVES: To perform a meta-analysis on the global prevalence of metabolic syndrome (MetS) in postmenopausal women. The meta-analysis also sought to measure the relationship menopause status has with MetS and its components. METHODS: The Web of Science, Medline, PubMed, Scopus, Embase, CINAHL, DOAJ, and Google Scholar were all searched using the relevant keywords. Articles published during the period 2004 to 2017 that met our inclusion criteria and reported the prevalence of MetS among premenopausal and postmenopausal women were included...
May 21, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29787421/the-impact-of-saphenous-vein-sparing-during-inguinal-lymphadenectomy-on-postoperative-morbidity-in-women-with-vulval-cancer-an-updated-per-groin-meta-analysis-of-short-term-outcomes
#10
Anastasios Tranoulis, Alexandros Laios, George Theophilou, Konstantinos Bramis, Sean Kehoe
OBJECTIVE: Inguinofemoral lymphadenectomy (IFL) is included in the standard surgical management of early-stage vulval cancer (VC) but is often accompanied by surgical complications. Efforts have been made to limit the postoperative morbidity by adopting more conservative IFL techniques without compromising the surgical outcomes. Saphenous vein (SV) preservation during IFL for VC appears to reduce the incidence of postoperative complications including lymphedema. To ascertain the efficacy of SV preservation, we aimed to revisit the impact of SV preservation on short-term per groin complications by updating on a previous meta-analysis to further guide current clinical practice...
May 22, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29785971/community-noise-exposure-and-annoyance-activity-interference-and-academic-achievement-among-university-students
#11
Rattapon Onchang, Darryl W Hawker
Background: Noise annoyance and effects on academic performance have been investigated for primary and secondary school students but comparatively little work has been conducted with university students who generally spend more time in dormitories or accommodation for their self-study. Objective: To determine, using a socio-acoustic approach involving face-to-face interviews and actual noise measurements, the effect of various community noise sources on student activities in accommodation both inside and outside a university precinct and also relationships with cumulative grade point average (GPA)...
May 2018: Noise & Health
https://www.readbyqxmd.com/read/29785797/relationship-between-handgrip-strength-and-pulmonary-function-in-apparently-healthy-older-women
#12
Da-Hye Son, Ji-Won Yoo, Mi-Ra Cho, Yong-Jae Lee
OBJECTIVES: To investigate the relationship between handgrip strength and pulmonary function. DESIGN: Cross-sectional study of a representative sample of older Korean women. SETTING: The Korean National Health and Nutrition Examination Survey. PARTICIPANTS: Community-dwelling women aged 65 and older without chronic diseases or pulmonary disease (N=605). MEASUREMENTS: Handgrip strength was measured using a digital hand dynamometer, and pulmonary function was tested according to guidelines of the American Thoracic Society/European Respiratory Society using a spirometry system...
May 21, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29785256/job-titles-classified-into-socioeconomic-and-occupational-groups-identify-subjects-with-increased-risk-for-respiratory-symptoms-independent-of-occupational-exposure-to-vapour-gas-dust-or-fumes
#13
Christian Schyllert, Martin Andersson, Linnea Hedman, Magnus Ekström, Helena Backman, Anne Lindberg, Eva Rönmark
Objectives : To evaluate the ability of three different job title classification systems to identify subjects at risk for respiratory symptoms and asthma by also taking the effect of exposure to vapours, gas, dust, and fumes (VGDF) into account. Background : Respiratory symptoms and asthma may be caused by occupational factors. There are different ways to classify occupational exposure. In this study, self-reported occupational exposure to vapours, gas, dust and fumes was used as well as job titles classifed into occupational and socioeconomic Groups according to three different systems...
2018: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29785120/association-between-nr5a2-and-the-risk-of-pancreatic-cancer-especially-among-caucasians-a-meta-analysis-of-case-control-studies
#14
Qun Chen, Hao Yuan, Guo-Dong Shi, Yang Wu, Dong-Fang Liu, Yu-Ting Lin, Lei Chen, Wan-Li Ge, Kuirong Jiang, Yi Miao
Background: Previous studies have reported that nuclear receptor subfamily 5, group A, member 2 (NR5A2) polymorphisms (rs3790843 G>A, rs3790844 T>C, rs12029406 C>T) are associated with the risk of pancreatic cancer. However, the results of epidemiological investigations are still controversial. In order to explore its potential attributing factors, we pooled the updated literatures to evaluate the association between NR5A2 polymorphism and the risk of pancreatic cancer in this meta-analysis...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29782935/vitamin-d-status-and-the-risk-of-type-2-diabetes-the-melbourne-collaborative-cohort-study
#15
Alicia K Heath, Elizabeth J Williamson, Allison M Hodge, Peter R Ebeling, Darryl W Eyles, David Kvaskoff, Kerin O'Dea, Graham G Giles, Dallas R English
AIMS: Inverse associations between vitamin D status and risk of type 2 diabetes observed in epidemiological studies could be biased by confounding and reverse causality. We investigated the prospective association between vitamin D status and type 2 diabetes and the possible role of reverse causality. METHODS: We conducted a case-cohort study within the Melbourne Collaborative Cohort Study (MCCS), including a random sample of 628 participants who developed diabetes and a sex-stratified random sample of the cohort (n=1,884)...
May 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29782484/implications-for-human-odor-sensing-revealed-from-the-statistics-of-odorant-receptor-interactions
#16
Ji Hyun Bak, Seogjoo J Jang, Changbong Hyeon
Binding of odorants to olfactory receptors (ORs) elicits downstream chemical and neural signals, which are further processed to odor perception in the brain. Recently, Mainland and colleagues have measured more than 500 pairs of odorant-OR interaction by a high-throughput screening assay method, opening a new avenue to understanding the principles of human odor coding. Here, using a recently developed minimal model for OR activation kinetics, we characterize the statistics of OR activation by odorants in terms of three empirical parameters: the half-maximum effective concentration EC50, the efficacy, and the basal activity...
May 21, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29782466/mucin-expression-in-colorectal-cancer-crc-systematic-review-and-meta-analysis
#17
Yaron Niv, Theodore Rokkas
BACKGROUND: A body of evidence has suggested that mucins play an important role in adhesion, invasion, and cancer metastasis. However, this evidence is scarce and sometimes confusing. OBJECTIVE: We performed a systematic review and meta-analysis of available studies to better define the role of mucins in the behavior of colorectal cancer (CRC). METHODS: Medical literature was searched through November 30, 2017, using suitable keywords. Pooled estimates, that is, odd ratios (ORs), were obtained using fixed or random-effects models, as appropriate...
May 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29782194/five-common-functional-polymorphisms-in-micrornas-and-susceptibility-to-breast-cancer-an-updated-meta-analysis
#18
Jie Wu, Yusi Wang, Lihua Shang, Lichun Qi, Mowei Song
AIMS: microRNAs (miRNA) play a key role in the pathogenesis of breast cancer (BC) as regulators of tumor-associated genes, and understanding their polymorphisms is critical to the control of breast carcinogenesis. Thus, the present study explored the association between five common functional polymorphisms in miRNAs (i.e., miRNA-196a2C>T, rs11614913; miRNA-146aG>C, rs2910164; miRNA-423C>A, rs6505162; miRNA-608G>C, rs4919510; miRNA-27aC>T, rs895819) and the risk of BC. MATERIALS AND METHODS: Meta-analyses were performed on 31 studies, including 14,677 BC patients and 16,143 cancer-free controls...
May 21, 2018: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/29782058/familial-aggregation-of-major-depressive-disorder-in-an-african-american-community
#19
Eleanor Murphy, James E Gangwisch, Janet T Matsunaga, Ruth Ottman
BACKGROUND: African Americans (AAs) with major depressive disorder (MDD) experience more impairment and poorer treatment outcomes relative to Whites, yet are underrepresented in family studies of MDD. This is the first study to investigate the familial aggregation of major depression among AAs. METHODS: Participants' reports of depression from clinical and family history (FH) interviews were used to examine depression rates among 435 first-degree relatives and half-siblings of 63 depressed cases and 222 relatives of 33 nondepressed controls...
May 21, 2018: Depression and Anxiety
https://www.readbyqxmd.com/read/29781671/breed-prevalence-of-canine-lymphoma-in-south-africa
#20
Liesl J Van Rooyen, Emma Hooijberg, Fred Reyers
Lymphoma is a common haematopoietic neoplasm in dogs. Several breeds have been shown to have a predisposition to lymphoma; however, very little information exists regarding the South African dog population. This study assessed whether any breed had increased odds of developing lymphoma compared with others, and also investigated the effects of age, sex and neutering status on disease prevalence. Two study populations and their corresponding reference populations were studied retrospectively. Odds ratios (ORs) for lymphoma in 49 dog breeds, together with their 95% confidence intervals (CI), were calculated...
March 8, 2018: Journal of the South African Veterinary Association
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