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zinc sulfate for gastroenteritis

Bernadeta Patro, Henryk Szymański, Hania Szajewska
OBJECTIVE: To evaluate the efficacy and safety of zinc in the treatment of acute gastroenteritis (AGE) in children in Poland. STUDY DESIGN: Children aged 3 to 48 months with AGE were enrolled in a randomized, double-blind, placebo-controlled trial in which they received zinc sulfate (10 or 20 mg/day depending on age) or placebo for 10 days. A total of 141 of 160 children recruited were available for intention-to-treat analysis. The primary outcome was the duration of diarrhea...
December 2010: Journal of Pediatrics
C Castillo-Durán, P Vial, R Uauy
To evaluate the effect of copper supplementation during recovery from acute diarrhea, we randomly assigned 14 hospitalized infants to receive either 80 micrograms copper body wt-1.d-1 or a placebo. Metabolic balance and plasma copper and zinc concentrations were measured before randomization (period 1) and 6 d after admission (period 2). Fifteen control subjects were studied after respiratory illness. Fecal copper was not affected by supplementation; fecal zinc during period 2 rose significantly only in the copper-supplemented group...
June 1990: American Journal of Clinical Nutrition
J Bohac, J B Derbyshire, J Thorsen
Parathyroid (PT) glands from 20-day-old embryonic chicks cultured in a chemically defined medium secreted a stimulator of in vitro bone resorption. This stimulator was presumed to be parathyroid hormone (PTH) because: 1) the in vitro dose response curve was parallel to that obtained with bovine PTH; 2) the activity was eluted on Sephadex G-1--chromatography at a postition similar to that for PTH; and 3) the material produced hypercalcemia in vivo in chicks. The amount of PTH-activity secreted was inversely proportional to the calcium concentration of the medium over the range of 0...
January 1975: Canadian Journal of Comparative Medicine. Revue Canadienne de Médecine Comparée
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