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https://www.readbyqxmd.com/read/27867668/a-rare-clinical-course-of-seronegative-pulmonary-renal-syndrome
#1
M Fröhlich-Gildhoff, W J Jabs, C Berhold, M K Kuhlmann, U Ketterer, S Kische, H Ince
Purpose. Pulmonary-renal syndrome (PRS) is characterized by diffuse alveolar hemorrhage and rapidly progressive glomerulonephritis mainly due to autoimmune etiologies. Seronegative PRS is a challenging entity to the clinician, since early diagnosis may be missed leading to delayed appropriate treatment. Materials and Methods. We present the clinical course of a 77-year-old patient who was admitted under the suspected diagnosis of pneumogenic sepsis and septic renal failure with fever, dyspnea, and elevated CRP levels...
2016: Case Reports in Critical Care
https://www.readbyqxmd.com/read/27851129/1493-outcomes-of-patients-with-sepsis-related-to-staphalococcus-aureus-managed-with-ecmo
#2
Angelina June, Adnan Bhutta, Adrian Holloway, Dayanand Bagdure, Jason Custer
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851095/1459-venoarterial-extracorporeal-membrane-oxygenation-for-severe-sepsis-and-septic-shock-in-3-195-adults
#3
Shuhei Takauji, Mineji Hayakawa, Kota Ono, Satoshi Fujita
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27851035/1399-outcomes-of-pediatric-patients-with-sepsis-managed-on-extracorporeal-membrane-oxygenation
#4
Jason Custer, Adnan Bhutta, Dayanand Bagdure, Adrian Holloway, Angelina June
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27842680/an-evolving-paradigm-for-adult-extracorporeal-membrane-oxygenation-should-the-indications-include-patients-with-sepsis
#5
EDITORIAL
Kevin Landolfo, Erol Belli
No abstract text is available yet for this article.
December 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27822747/venovenous-extracorporeal-membrane-oxygenation-for-ards-outcome-analysis-of-a-croatian-referral-center-for-respiratory-ecmo
#6
Marko Kutleša, Anđa Novokmet, Renata Josipović Mraović, Bruno Baršić
BACKGROUND: The use of venovenous extracorporeal membrane oxygenation (VV-ECMO) as a rescue therapy in severe acute respiratory distress syndrome (ARDS) has become well established; however, the affirmation of evidence on VV-ECMO application and the analysis of patient outcomes after VV-ECMO treatment for ARDS continues. The aim of the study is to identify variables that affected the outcome of patients treated with VV-ECMO for severe ARDS outside a major ECMO center. METHODS: The study included adult patients with severe ARDS treated with ECMO at a tertiary care hospital in Zagreb, Croatia between October 2009 and July 2014...
November 7, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27806995/septic-porcine-blood-does-not-further-activate-coagulation-during-in-vitro-membrane-oxygenation
#7
Christian Bleilevens, Oliver Grottke, Sabine Groening, Markus Honickel, Rüdger Kopp, Smriti Singh, Jutta Arens, Rolf Rossaint
OBJECTIVES: For patients with a severe acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) represents a life-saving measure. Frequently, patients with severe ARDS also show signs of severe sepsis. As blood contact with the membrane oxygenator surface leads to adverse effects due to insufficient biocompatibility partly caused by activation of platelets, coagulation factors and leucocytes, we hypothesized that these adverse effects would be amplified if septic blood in a preactivated state came into contact with the membrane oxygenator...
November 2, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27749512/2016-update-for-the-rogers-textbook-of-pediatric-intensive-care-recognition-and-initial-management-of-shock
#8
Julie C Fitzgerald, Scott L Weiss, Niranjan Kissoon
OBJECTIVE: To review important articles in the field of pediatric shock and pediatric septic shock published subsequent to the Fifth Edition of the Rogers' Textbook of Pediatric Intensive Care. DATA SOURCES: The U.S. National Library of Medicine PubMed (www.ncbi.nlm.nih.gov/pubmed) was searched for combination of the term "pediatric" and the following terms: "sepsis, septic shock, shock, antibiotics, extracorporeal membrane oxygenation, and steroid." The abstract lists generated by these searches were screened for potential inclusion...
November 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27717334/early-antibiotics-administration-during-targeted-temperature-management-after-out-of-hospital-cardiac-arrest-a-nationwide-database-study
#9
Takashi Tagami, Hiroki Matsui, Masamune Kuno, Yuuta Moroe, Junya Kaneko, Kyoko Unemoto, Kiyohide Fushimi, Hideo Yasunaga
BACKGROUND: Patients resuscitated after cardiac arrest are reportedly at high risk for infection and sepsis, especially those treated with targeted temperature management (TTM). There is, however, limited evidence suggesting that early antibiotic use improves patient outcomes. We examined the hypothesis that early treatment with antibiotics reduces mortality in patients with cardiac arrest receiving TTM. METHODS: We identified 2803 patients with cardiogenic out-of-hospital cardiac arrest (OHCA) that were treated with TTM and were admitted to 371 hospitals that contribute to the Japanese Diagnosis Procedure Combination inpatient database between July 2007 and March 2013...
October 7, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27692951/predictors-of-survival-in-adults-undergoing-extracorporeal-membrane-oxygenation-with-severe-infections
#10
Aristine Cheng, Hsin-Yun Sun, Mao-Song Tsai, Wen-Je Ko, Pi-Ru Tsai, Fu-Chang Hu, Yee-Chun Chen, Shan-Chwen Chang
BACKGROUND: To identify novel factors associated with the survival of septic adults receiving extracorporeal membrane oxygenation (ECMO) to improve patient selection and outcomes. METHODS: Cases were identified from our ECMO registry from 2001 to 2011 if they were ≥16 years and received ECMO for life-threatening sepsis. RESULTS: A total of 151 adults with a median (25th-75th percentile) age of 51 (37-63) years were analyzed. Pneumonia (50%), myocarditis (20%), and primary bloodstream infections (15%) were the main types of infection, caused by predominantly nonfermentative Gram-negative bacteria (NFGNB) (26%), Enterobacteriaceae (24%), and Gram-positive cocci (21%)...
August 30, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27670223/extracorporeal-membrane-oxygenation-for-hemophagocytic-lymphohistiocytosis
#11
Victoria Anne Saites, Rachel Hadler, Jacob Thomas Gutsche, Krzysztof Laudanski
BACKGROUND Hemophagocytic lymphohistiocytosis (HLH) is a rare hematological disease characterized by an excessive inflammatory response to various triggers, resulting in rapid multi-organ failure. Its incidence may be underestimated due to its rarity, its variable clinical presentation, and its high mortality rate prior to diagnosis. Oftentimes, HLH is mistaken for refractory sepsis and improperly treated as such. Left untreated, the disease is universally fatal. With treatment, case series of adults with HLH report a 30-day mortality of up to 44% and an overall mortality of up to 75%...
September 27, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27666781/serial-lactate-measurements-as-a-prognostic-tool-in-venovenous-extracorporeal-membrane-oxygenation-support
#12
Manuela Bonizzoli, Chiara Lazzeri, Giovanni Cianchi, Maria Boddi, Morena Cozzolino, Simona Di Valvasone, Paolo Terenzi, Stefano Batacchi, Marco Chiostri, Adriano Peris
BACKGROUND: Serial lactate measurements over time or lactate clearance has been reported to be clinically reliable for risk stratification in different pathologic conditions ranging from sepsis to trauma, but no data are so far available on the behavior of lactate during venovenous extracorporeal membrane oxygenation (VV-ECMO) support in refractory adult acute respiratory distress syndrome (ARDS). METHODS: We assessed lactate values during VV-ECMO support and the prognostic role of lactate clearance at 6, 24, and 72 hours after ECMO start in 126 consecutive patients with refractory ARDS treated with VV-ECMO...
September 22, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27596367/-complex-control-of-the-source-of-infection-in-sepsis-extracorporeal-membrane-oxygenation-ecmo-as-a%C3%A2-bridging-concept-for-tracheal-fistula-repair-in-sepsis-associated-ards
#13
S Weiterer, K Schmidt, M Deininger, A Ulrich, U Tochtermann, R Eberhardt, S Hofer, M A Weigand, T Brenner
Here, we present a case of a tracheal fistula due to an anastomotic insufficiency following abdominothoracic esophageal resection. Despite immediate discontinuity resection, the tracheal fistula could not be surgically closed, resulting in incomplete control of the source of infection and an alternative treatment concept in the form of interventional fistula closure using a Y-tracheal stent. However, owing to existing severe acute respiratory distress syndrome (ARDS), which is associated with a considerable risk of peri-interventional hypoxia, a temporary bridging concept using venovenous extracorporeal membrane oxygenation (ECMO) was implemented successfully...
September 2016: Der Anaesthesist
https://www.readbyqxmd.com/read/27576283/-acute-respiratory-distress-syndrome
#14
Elisa Estenssoro, Arnaldo Dubin
Acute respiratory distress syndrome (ARDS) is an acute respiratory failure produced by an inflammatory edema secondary to increased lung capillary permeability. This causes alveolar flooding and subsequently deep hypoxemia, with intrapulmonary shunt as its most important underlying mechanism. Characteristically, this alteration is unresponsive to high FIO2 and only reverses with end-expiratory positive pressure (PEEP). Pulmonary infiltrates on CXR and CT are the hallmark, together with decreased lung compliance...
2016: Medicina
https://www.readbyqxmd.com/read/27562206/role-of-technology-for-the-management-of-aki-in-critically-ill-patients-from-adoptive-technology-to-precision-continuous-renal-replacement-therapy
#15
J Cerdá, I Baldwin, P M Honore, G Villa, John A Kellum, Claudio Ronco
This paper reports on the continuous renal replacement therapy (CRRT) technology group recommendations and research proposals developed during the 17th Acute Dialysis Quality Initiative Meeting in Asiago, Italy. The group was tasked to address questions related to the impact of technology on acute kidney injury management. We discuss technological aspects of the decision to initiate CRRT and the components of the treatment prescription and delivery, the integration of information technology (IT) on overall patient management, the incorporation of CRRT into other 'non-renal' extracorporeal technologies such as ECMO and ECCO2R and the use of sorbents in sepsis and propose new areas for future research...
2016: Blood Purification
https://www.readbyqxmd.com/read/27548818/development-and-validation-of-a-score-to-predict-mortality-in-children-undergoing-extracorporeal-membrane-oxygenation-for-respiratory-failure-pediatric-pulmonary-rescue-with-extracorporeal-membrane-oxygenation-prediction-score
#16
David K Bailly, Ron W Reeder, Luke A Zabrocki, Anna M Hubbard, Jacob Wilkes, Susan L Bratton, Ravi R Thiagarajan
OBJECTIVE: Our objective was to develop and validate a prognostic score for predicting mortality at the time of extracorporeal membrane oxygenation initiation for children with respiratory failure. Preextracorporeal membrane oxygenation mortality prediction is important for determining center-specific risk-adjusted outcomes and counseling families. DESIGN: Multivariable logistic regression of a large international cohort of pediatric extracorporeal membrane oxygenation patients...
August 19, 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27465098/adverse-outcomes-in-neonates-and-children-with-pulmonary-artery-hypertension-supported-with-ecmo
#17
Viviane G Nasr, David Faraoni, James A DiNardo, Ravi R Thiagarajan
Extracorporeal membrane oxygenation (ECMO) has been increasingly used to rescue neonates and children with cardiac or respiratory failure, and critical illnesses including pulmonary artery hypertension (PAH) unresponsive to conventional therapies. This study assesses mortality and outcomes in neonates and children with PAH supported with ECMO. Neonates and children from the 2012 Health Care Cost and Use Project Kids' Database were identified using ICD-9 codes. Children with congenital heart disease were excluded...
November 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/27436116/postcardiotomy-ecmo-support-after-high-risk-operations-in-adult-congenital-heart-disease
#18
Benjamin Acheampong, Jonathan N Johnson, John M Stulak, Joseph A Dearani, Sudhir S Kushwaha, Richard C Daly, Dawit T Haile, Gregory J Schears
BACKGROUND: Cardiac operations in high-risk adult congenital heart disease (ACHD) patients may require mechanical circulatory support (MCS), such as extracorporeal membrane oxygenation (ECMO) or intraaortic balloon pump (IABP), to allow the cardiopulmonary system to recover. METHODS: We reviewed records for all ACHD patients who required MCS following cardiotomy at our institution from 1/2001 to 12/2013. RESULTS: During the study period, 2264 (mean age 39...
July 20, 2016: Congenital Heart Disease
https://www.readbyqxmd.com/read/27436098/combination-of-ecmo-and-cytokine-adsorption-therapy-for-severe-sepsis-with-cardiogenic-shock-and-ards-due-to-panton-valentine-leukocidin-positive-staphylococcus-aureus-pneumonia-and-h1n1
#19
N J Lees, Ajp Rosenberg, A I Hurtado-Doce, J Jones, N Marczin, M Zeriouh, A Weymann, A Sabashnikov, A R Simon, A F Popov
Sepsis-induced cardiogenic shock in combination with severe acute respiratory failure represents a life-threatening combination that is often refractory to the conventional methods of treatment. We describe the case of a 33-year-old patient who developed acute cardiovascular collapse and ARDS secondary to superinfection of Panton-Valentine leukocidin-positive Staphylococcus aureus and H1N1 pneumonia who underwent successful combination therapy for severe sepsis-related cardiomyopathy and respiratory failure using extracorporeal membrane oxygenation and cytokine adsorption therapy...
July 19, 2016: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/27344436/protein-c-zymogen-in-severe-sepsis-a-double-blinded-placebo-controlled-randomized-study
#20
Federico Pappalardo, Martina Crivellari, Ambra L Di Prima, Nataliya Agracheva, Malgorzata Celinska-Spodar, Rosalba Lembo, Daiana Taddeo, Giovanni Landoni, Alberto Zangrillo
PURPOSE: To determine whether protein C zymogen (protein C concentrates or human protein C) improves clinically relevant outcomes in adult patients with severe sepsis and septic shock. METHODS: This is a randomized, double-blind, placebo-controlled, parallel-group trial that from September 2012 to June 2014 enrolled adult patients with severe sepsis or septic shock and high risk of death and of bleeding (e.g., APACHE II greater than 25, extracorporeal membrane oxygenation or disseminated intravascular coagulopathy)...
November 2016: Intensive Care Medicine
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