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Prescribing errors

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https://www.readbyqxmd.com/read/28726170/prescribing-trends-in-a-glaucoma-clinic-and-adherence-to-egs-guidelines-a-retrospective-non-interventional-single-center-uk-study
#1
Mark Fajgenbaum, Ejaz Ansari
INTRODUCTION: The purpose of this study was to determine prescribing trends in a specialist glaucoma clinic in the UK. Specifically, the aims were to determine which drugs were prescribed as first-, second-, and third-line treatment, the persistence of first-, second-, and third-line treatment regimens, and the proportion of treatment decisions conforming to the European Glaucoma Society (EGS) guidelines. METHODS: A retrospective, non-interventional, single-center, case-note review was performed on a cohort of consecutive patients presenting to a specialist glaucoma clinic for follow-up...
July 19, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28722562/centers-of-excellence-in-healthcare-institutions-what-they-are-and-how-to-assemble-them
#2
James K Elrod, John L Fortenberry
BACKGROUND: Centers of excellence-specialized programs within healthcare institutions which supply exceptionally high concentrations of expertise and related resources centered on particular medical areas and delivered in a comprehensive, interdisciplinary fashion-afford many advantages for healthcare providers and the populations they serve. To achieve full value from centers of excellence, proper assembly is an absolute necessity, but guidance is somewhat limited. This effectively forces healthcare providers to pursue establishment largely via trial-and-error, diminishing opportunities for success...
July 11, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28713798/incidence-and-severity-of-prescribing-errors-in-parenteral-nutrition-for-pediatric-inpatients-at-a-neonatal-and-pediatric-intensive-care-unit
#3
Theresa Hermanspann, Mark Schoberer, Eva Robel-Tillig, Christoph Härtel, Rangmar Goelz, Thorsten Orlikowsky, Albrecht Eisert
OBJECTIVES: Pediatric inpatients are particularly vulnerable to medication errors (MEs), especially in highly individualized preparations like parenteral nutrition (PN). Aside from prescribing via a computerized physician order entry system (CPOE), we evaluated the effect of cross-checking by a clinical pharmacist to prevent harm from PN order errors in a neonatal and pediatric intensive care unit (NICU/PICU). METHODS: The incidence of prescribing errors in PN in a tertiary level NICU/PICU was surveyed prospectively between March 2012 and July 2013 (n = 3,012 orders)...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28703072/-it-s-up-to-nurses-to-tell-politicians-how-it-is
#4
Layla Haidrani
What is your job? I am a practising advanced nurse practitioner in urgent first contact care and visiting professor of prescribing and medicines at Birmingham City University. I also have roles with the Resuscitation Council UK and the British National Formulary. As an independent consultant, I work with organisations to investigate errors, as well as chairing and presenting conferences.
July 13, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/28698975/exploring-the-impact-of-feedback-on-prescribing-error-rates-a-pilot-study
#5
Michael Lloyd, Simon David Watmough, Sarah Victoria O'Brien, Kevin Hardy, Niall Furlong
Background Prescribing errors are prevalent in hospital settings with feedback identified as one potential error reduction strategy. Hospital pharmacists work alongside prescribers at ward level and are credible facilitators of prescribing error feedback. A formalised programme of pharmacist-led prescribing error feedback was designed and implemented Objective To determine the impact of the feedback intervention on prescribing error rates. Method Prospective prescribing audits were undertaken at baseline for control (n = 11) and intervention group (n = 10) prescribers...
July 11, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28694232/reinforcement-of-an-antimicrobial-stewardship-task-force-aims-at-a-better-use-of-antibiotics-of-last-resort-the-colitifos-study
#6
Benjamin Davido, Frédérique Bouchand, Aurélien Dinh, Christian Perronne, Maryvonne Villart, Olivia Senard, Jérome Salomon
BACKGROUND: Physicians are facing a worldwide increase in multidrug-resistant (MDR) organisms. Eradication of such bacteria, including so called superbugs (XDR), may cause physicians to prescribe last-resort antibiotics. However, experience with these drugs is limited and few data are available. METHODS: A before and after retrospective study was conducted from January 2008 to June 2016. Prescriptions of parenteral antimicrobials considered as last-resort antibiotics (colistin, fosfomycin, tigecycline and temocillin) were reviewed by 4 infectious disease specialists (according to microbiology results, susceptibility testing, clinical situation and alternative agents), while doses were analyzed by a pharmacist...
July 7, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28685047/prioritizing-medication-safety-in-care-of-people-with-cancer-clinicians-views-on-main-problems-and-solutions
#7
Lorainne Tudor Car, Nikolaos Papachristou, Catherine Urch, Azeem Majeed, Rifat Atun, Josip Car, Charles Vincent
BACKGROUND: Cancer care is liable to medication errors due to the complex nature of cancer treatment, the common presence of comorbidities and the involvement of a number of clinicians in cancer care. While the frequency of medication errors in cancer care has been reported, little is known about their causal factors and effective prevention strategies. With a unique insight into the main safety issues in cancer treatment, frontline staff can help close this gap. In this study, we aimed to identify medication safety priorities in cancer patient care according to clinicians in North West London using PRIORITIZE, a novel priority-setting approach...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28684456/optimization-of-dsc-mri-echo-times-for-cbv-measurements-using-error-analysis-in-a-pilot-study-of-high-grade-gliomas
#8
L C Bell, M D Does, A M Stokes, L C Baxter, K M Schmainda, A C Dueck, C C Quarles
BACKGROUND AND PURPOSE: The optimal TE must be calculated to minimize the variance in CBV measurements made with DSC MR imaging. Simulations can be used to determine the influence of the TE on CBV, but they may not adequately recapitulate the in vivo heterogeneity of precontrast T2*, contrast agent kinetics, and the biophysical basis of contrast agent-induced T2* changes. The purpose of this study was to combine quantitative multiecho DSC MRI T2* time curves with error analysis in order to compute the optimal TE for a traditional single-echo acquisition...
July 6, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28684117/exploring-the-impact-of-pharmacist-led-feedback-on-prescribing-behaviour-a-qualitative-study
#9
M Lloyd, S D Watmough, S V O'Brien, N Furlong, K Hardy
BACKGROUND: Prescribing errors occur frequently in hospital settings. Interventions to influence prescribing behaviour are needed with feedback one potential intervention to improve prescribing practice. Doctors have reported a lack of feedback on their prescribing previously whilst the literature exploring the impact of feedback on prescribing behaviour is limited. OBJECTIVES: To explore the impact of pharmacist-led feedback on prescribing behaviour. METHODS: Semi-structured interviews were conducted with doctors who had received prescribing error feedback...
June 29, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28681976/mixed-integer-programming-with-dose-volume-constraints-in-intensity-modulated-proton-therapy
#10
Pengfei Zhang, Neng Fan, Jie Shan, Steven E Schild, Martin Bues, Wei Liu
BACKGROUND: In treatment planning for intensity-modulated proton therapy (IMPT), we aim to deliver the prescribed dose to the target yet minimize the dose to adjacent healthy tissue. Mixed-integer programming (MIP) has been applied in radiation therapy to generate treatment plans. However, MIP has not been used effectively for IMPT treatment planning with dose-volume constraints. In this study, we incorporated dose-volume constraints in an MIP model to generate treatment plans for IMPT...
July 6, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28678722/adaptive-neural-networks-prescribed-performance-control-design-for-switched-interconnected-uncertain-nonlinear-systems
#11
Yongming Li, Shaocheng Tong
In this paper, an adaptive neural networks (NNs)-based decentralized control scheme with the prescribed performance is proposed for uncertain switched nonstrict-feedback interconnected nonlinear systems. It is assumed that nonlinear interconnected terms and nonlinear functions of the concerned systems are unknown, and also the switching signals are unknown and arbitrary. A linear state estimator is constructed to solve the problem of unmeasured states. The NNs are employed to approximate unknown interconnected terms and nonlinear functions...
June 28, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28676750/multi-trial-gait-adaptation-of-healthy-individuals-during-visual-kinematic-perturbations
#12
Trieu Phat Luu, Yongtian He, Sho Nakagome, Kevin Nathan, Samuel Brown, Jeffrey Gorges, Jose L Contreras-Vidal
Optimizing rehabilitation strategies requires understanding the effects of contextual cues on adaptation learning. Prior studies have examined these effects on the specificity of split-belt walking adaptation, showing that contextual visual cues can be manipulated to modulate the magnitude, transfer, and washout of split-belt-induced learning in humans. Specifically, manipulating the availability of vision during training or testing phases of learning resulted in differences in adaptive mechanisms for temporal and spatial features of walking...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28666904/actual-target-coverage-after-setup-verification-using-surgical-clips-compared-with-external-skin-markers-in-postoperative-breast-cancer-radiation-therapy
#13
Anke van der Salm, Lars Murrer, Inge Steenbakkers, Ruud Houben, Liesbeth J Boersma
PURPOSE: After changing from offline setup verification to online setup verification using external skin markers in breast cancer patients, we noticed an increase in localized acute skin toxicity beneath the markers. Also, in vivo 3-dimensional dose measurements showed deviations between the delivered and the planned dose distributions; therefore, we investigated the accuracy of setup verification using surgical clips in the tumor bed, with a focus on target coverage of whole breast and tumor bed...
April 19, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28658078/comparison-of-incremental-intermittent-and-time-trial-testing-in-age-group-swimmers
#14
Rodrigo Zacca, Rui Azevedo, Ricardo Peterson Silveira, João Paulo Vilas-Boas, David B Pyne, Flávio A de S Castro, Ricardo J Fernandes
The aim of this study was to compare physiological and biomechanical characteristics between an incremental intermittent test and a time trial protocol in age-group swimmers. 11 national level age-group swimmers (6 male and 5 female) performed a 7 x 200-m incremental intermittent protocol (until exhaustion; 30 s rest) and a 400-m test (T400) in front crawl on separate days. Cardiorespiratory variables were measured continuously using a telemetric portable gas analyzer. Swimming speed, stroke rate, stroke length and stroke index were assessed by video analysis...
June 22, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28657855/errors-associated-with-utilizing-prescribed-scapular-kinematics-to-estimate-unconstrained-natural-upper-extremity-motion-in-musculoskeletal-modeling
#15
R Tyler Richardson, Elizabeth A Rapp, R Garry Quinton, Kristen F Nicholson, Brian A Knarr, Stephanie A Russo, Jill S Higginson, James G Richards
Musculoskeletal modeling is capable of estimating physiological parameters that cannot be directly measured, however, the validity of the results must be assessed. Several models utilize a scapular rhythm to prescribe kinematics, yet it is unknown how well they replicate natural scapular motion. This study evaluated kinematic errors associated with a model that employs a scapular rhythm using two shoulder movements - abduction and forward reach. Two versions of the model were tested - the original MoBL ARMS model that utilizes a scapular rhythm, and a modified MoBL ARMS model that permits unconstrained scapular motion...
June 28, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28655357/drug-related-problems-and-medication-reviews-among-old-people-with-dementia
#16
Bettina Pfister, Jeanette Jonsson, Maria Gustafsson
BACKGROUND: Drug-related problems, including medication errors and adverse drug events, are common among old people. Due to, for example, greater susceptibility to side effects, people with dementia are even more at risk of drug-related problems. The objectives of this study were to assess the occurrence and character of drug-related problems found among old people with dementia or cognitive impairment. METHODS: Data from a randomized controlled clinical trial exploring the effects of a pharmacist intervention as part of a hospital ward team in patients 65 years and older with dementia or cognitive impairment were used...
June 27, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28653940/review-medication-errors-and-strategies-for-their-prevention
#17
Muhammad Kashif Riaz, Mohammad Riaz, Abida Latif
Medication errors occur every day causing injury to the patients and even deaths. The health care professionals are not fully aware of the damages done by medication errors in terms of patients' discomfort and economic burden. There is a need to provide information about medication errors to health care providers. This article reviews research done on the various aspects of medication errors. The research work done on prescribing errors, transcribing errors, dispensing errors, administration errors and discharged summaries errors have been examined...
May 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28653203/ras-screening-in-colorectal-cancer-a-comprehensive-analysis-of-the-results-from-the-uk-neqas-colorectal-cancer-external-quality-assurance-schemes-2009-2016
#18
Susan D Richman, Jennifer Fairley, Rachel Butler, Zandra C Deans
Evidence strongly indicates that extended RAS testing should be undertaken in mCRC patients, prior to prescribing anti-EGFR therapies. With more laboratories implementing testing, the requirement for External Quality Assurance schemes increases, thus ensuring high standards of molecular analysis. Data was analysed from 15 United Kingdom National External Quality Assessment Service (UK NEQAS) for Molecular Genetics Colorectal cancer external quality assurance (EQA) schemes, delivered between 2009 and 2016. Laboratories were provided annually with nine colorectal tumour samples for genotyping...
June 26, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28647814/the-effects-of-variable-practice-on-locomotor-adaptation-to-a-novel-asymmetric-gait
#19
Jacob W Hinkel-Lipsker, Michael E Hahn
Very little is known about the effects of specific practice on motor learning of predictive balance control during novel bipedal gait. This information could provide an insight into how the direction and magnitude of predictive errors during acquisition of a novel gait task influence transfer of balance control, as well as yield a practice protocol for the restoration of balance for those with locomotor impairments. This study examined the effect of a variable practice paradigm on transfer of a novel asymmetric gait pattern in able-bodied individuals...
June 24, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28643030/hospital-electronic-prescribing-system-implementation-impact-on-discharge-information-communication-and-prescribing-errors-a-before-and-after-study
#20
Pamela Ruth Mills, Anita Elaine Weidmann, Derek Stewart
PURPOSE: The study aimed to test the hypothesis that hospital electronic prescribing and medicine administration system (HEPMA) implementation impacted patient discharge letter quality, nature and frequency of prescribing errors. METHOD: A quasi experimental before and after retrospective case note review was conducted in one United Kingdom district general hospital. The total sample size was 318 (random samples of 159 before and after implementation), calculated to achieve a 10% error reduction with a power of 80% and p < 0...
June 22, 2017: European Journal of Clinical Pharmacology
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