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Prescribing errors

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https://www.readbyqxmd.com/read/28933275/a-case-of-inappropriate-self-medication-compounded-with-prescribing-vis-%C3%A3-vis-dispensing-errors-and-the-hazardous-consequence
#1
Sukalyan Saha Roy, Anupam Roy, Ranjita Santra Dhali, Chiranjib Bagchi, Gautam Banerjee, Santanu K Tripathi
INTRODUCTION Dispensing error, a type of medication error, is not infrequent but seldom reported. Self-medication behavior appears to be a commonplace. And when it is ignorant it may prove dangerous. We report here a case of acute vesico-bullous eruptions from methotrexate in a patient of psoriasis who indulged in self-medication and was wrongfully dispensed higher doses of methotrexate. CASE DESCRIPTION A 50-year-old gentleman presented to the dermatology OPD with erythematous, vesico-bullar lesions spread all over the body including both limbs and scalp, with oral mucosal involvement without any history of fever...
September 19, 2017: Current Drug Safety
https://www.readbyqxmd.com/read/28925569/prescribing-errors-intercepted-by-pharmacist-intervention-in-care-of-patients-hospitalised-with-breast-and-gynaecological-cancer-at-a-brazilian-teaching-hospital
#2
A C Ferracini, A T Rodrigues, A A de Barros, S F Derchain, P G Mazzola
Oncologic inpatients often require multiple drug therapy. They may be at higher risk of experiencing prescribing errors, which pharmacist interventions may help to avoid. This study aimed to evaluate the types of prescribing errors, pharmaceutical interventions and differences in clinical significance, in prescriptions for hospitalised patients with breast and gynaecological cancer. A cross-sectional, prospective study was conducted at the oncology ward of a clinic specialised in breast and gynaecology cancer...
September 19, 2017: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28919061/efficacy-and-safety-of-dapagliflozin-in-patients-with-inadequately-controlled-type-1-diabetes-depict-1-24-week-results-from-a-multicentre-double-blind-phase-3-randomised-controlled-trial
#3
Paresh Dandona, Chantal Mathieu, Moshe Phillip, Lars Hansen, Steven C Griffen, Diethelm Tschöpe, Fredrik Thorén, John Xu, Anna Maria Langkilde
BACKGROUND: Dapagliflozin is a sodium-glucose cotransporter-2 inhibitor approved for the treatment of type 2 diabetes. We aimed to assess the efficacy and safety of dapagliflozin as an add-on to adjustable insulin in patients with inadequately controlled type 1 diabetes. METHODS: DEPICT-1 was a double-blind, randomised, parallel-controlled, three-arm, phase 3, multicentre study done at 143 sites in 17 countries. Eligible patients were aged 18-75 years and had inadequately controlled type 1 diabetes (HbA1c between ≥7·7% and ≤11·0% [≥61·0 mmol/mol and ≤97·0 mmol/mol]) and had been prescribed insulin for at least 12 months before enrolment...
September 13, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28918362/there-are-no-no-responders-to-low-or-high-resistance-training-volumes-among-older-women
#4
Matheus de Siqueira Mendes Barbalho, Paulo Gentil, Mikel Izquierdo, James Fisher, James Steele, Rodolfo de Azevedo Raiol
OBJECTIVES: To assess the prevalence of non-responders to different tests and to compare the effects of different resistance training (RT) volumes on muscle strength, anthropometric and functional performance of older women. METHODS: Three hundred seventy six women performed 12weeks of RT with either low or high volume (LV, 71.29±5.77years and HV 69.73±5.88years, respectively). Both groups performed the same exercises, and all parameters were held constant except for the number of sets performed per week...
September 13, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28905827/refractive-and-ocular-biometric-profile-of-children-with-a-history-of-laser-treatment-for-retinopathy-of-prematurity
#5
Savleen Kaur, Jaspreet Sukhija, Deeksha Katoch, Mansi Sharma, Ramanuj Samanta, Mangat R Dogra
PURPOSE: Indian children belong to a diverse socioeconomic strata with retinopathy of prematurity (ROP) developing in mature, higher birth weight babies as well. The purpose of our study is to analyze the long-term status of refractive errors and its relationship with ocular biometry in children with ROP who were laser treated at a tertiary center in North India. METHODS: Cross sectional study. Children (<16 years) enrolled from January 2014 to December 2014 with a history of laser treatment for ROP and examined for refractive and biometric status...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28900556/the-dynamic-leap-and-balance-test-dlbt-a-test-retest-reliability-study
#6
Abbis H Jaffri, Thomas M Newman, Brent I Smith, Sayers John Miller
BACKGROUND: There is a need for new clinical assessment tools to test dynamic balance during typical functional movements. Common methods for assessing dynamic balance, such as the Star Excursion Balance Test, which requires controlled movement of body segments over an unchanged base of support, may not be an adequate measure for testing typical functional movements that involve controlled movement of body segments along with a change in base of support. PURPOSE/HYPOTHESIS: The purpose of this study was to determine the reliability of the Dynamic Leap and Balance Test (DLBT) by assessing its test-retest reliability...
August 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28900321/pattern-of-adverse-drug-reactions-to-anticancer-drugs-a-quantitative-and-qualitative-analysis
#7
Shruti Singh, D C Dhasmana, Manisha Bisht, Prashant Kumar Singh
INTRODUCTION: Anticancer drugs contribute significantly to the global burden of adverse drug reactions (ADRs). Any attempt to quantify their magnitude and provide upgraded knowledge would help oncologists in writing safer prescriptions. AIM: This observational follow-up study was conducted on newly diagnosed cancer patients receiving anticancer therapy with an aim to determine the frequency, severity, causality, predictability, and preventability of ADRs. SUBJECTS AND METHODS: The patients were followed up for 6 months for the appearance of adverse events...
April 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28899617/better-medicines-for-neonates-improving-medicine-development-testing-and-prescribing
#8
Karel Allegaert
Pharmacotherapy is a powerful tool to improve the outcome of neonates. Unfortunately, the potential health impact of pharmacotherapy in neonates remains underexplored. This necessitates a structured approach to go beyond the current practice of trial and error, reflected in off-label prescription. The existing regulatory framework hereby provides a structure to reflect about aspects like pharmacokinetic models for dose selection and outcome assessment, including long-term safety. Future medicine development should also be driven by neonatal needs, diseases and pathophysiology, since surfactant is the latest product developed for preterm neonates...
September 9, 2017: Early Human Development
https://www.readbyqxmd.com/read/28885996/predesigned-labels-to-prevent-medication-errors-in-hospitalized-patients-a-quasi-experimental-design-study
#9
María Fernanda Morales-González, María Alejandra Galiano Gálvez
INTRODUCTION: Our institution implemented the use of pre-designed labeling of intravenous drugs and fluids, administration routes and infusion pumps of to prevent medication errors. OBJECTIVE: To evaluate the effectiveness of predesigned labeling in reducing medication errors in the preparation and administration stages of prescribed medication in patients hospitalized with invasive lines, and to characterize medication errors. METHODS: This is a pre/post intervention study...
September 8, 2017: Medwave
https://www.readbyqxmd.com/read/28879692/safety-and-effectiveness-of-once-daily-tadalafil-5-mg-therapy-in-korean-men-with-benign-prostatic-hyperplasia-lower-urinary-tract-symptoms-in-a-real-world-clinical-setting-results-from-a-post-marketing-surveillance-study
#10
Ji Eon Won, Ji Yeon Chu, Hyunah Caroline Choi, Yun Chen, Hyun Jun Park, Héctor José Dueñas
PURPOSE: The aim of this study was to investigate the safety and effectiveness of tadalafil 5 mg once daily (quaque die [everyday], QD) among Korean men with benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS) in a real-world clinical setting. MATERIALS AND METHODS: This was a single-country, prospective, observational cohort study in which patients newly prescribed tadalafil 5 mg QD for the treatment of BPH/LUTS were followed-up for 12±2 or 24±2 weeks, or to the last treatment, during post-marketing surveillance...
September 6, 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/28877642/to-assess-the-success-of-computerized-order-sets-and-pharmacy-education-modules-in-improving-antiretroviral-prescribing
#11
Dhara Mehta, Bella Kohn, Michael Blumenfeld, Harold W Horowitz
PURPOSE: To assess the success of order set and pharmacist training improvement (OSPTI) in improving prescription of antiretroviral therapy (ART) in a tertiary care, public, teaching hospital. METHODS: In this pre-OSPTI (January 2012 through June 2013) and post-OSPTI study (July 2013 through September 2014), an infectious disease pharmacist reviewed all patients on ART. A review of intervention data in July 2013 led to order-set changes in the hospital's computerized order entry system for frequently intervened on antiretrovirals: ritonavir, tenofovir, emtricitabine/tenofovir disoproxil fumarate (FTC/TDF), and lamivudine...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28874948/impact-of-internally-developed-electronic-prescription-on-prescribing-errors-at-discharge-from-the-emergency-department
#12
Eveline Hitti, Hani Tamim, Rinad Bakhti, Dina Zebian, Afif Mufarrij
INTRODUCTION: Medication errors are common, with studies reporting at least one error per patient encounter. At hospital discharge, medication errors vary from 15%-38%. However, studies assessing the effect of an internally developed electronic (E)-prescription system at discharge from an emergency department (ED) are comparatively minimal. Additionally, commercially available electronic solutions are cost-prohibitive in many resource-limited settings. We assessed the impact of introducing an internally developed, low-cost E-prescription system, with a list of commonly prescribed medications, on prescription error rates at discharge from the ED, compared to handwritten prescriptions...
August 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28871317/-drug-therapy-safety-at-the-transition-from-hospital-to-community-medicine
#13
M Hahn, S C Roll, J Klein
OBJECTIVE: We evaluated the qualitative and quantitative changes of medications during the stay on a geriatric-psychiatric ward where the medication was optimized by a clinical pharmacist, and after discharge. The goal of the study was to analyze the continuity of the medication at the transfer from hospital to ambulatory care. METHODS: We interviewed 41 patients on the phone about their drug regimen 4 and 12 weeks after discharge. Medications were compared to their discharge medication...
September 4, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28870178/using-total-quality-management-approach-to-improve-patient-safety-by-preventing-medication-error-incidences
#14
Nadin Yousef, Farah Yousef
BACKGROUND: Whereas one of the predominant causes of medication errors is a drug administration error, a previous study related to our investigations and reviews estimated that the incidences of medication errors constituted 6.7 out of 100 administrated medication doses. Therefore, we aimed by using six sigma approach to propose a way that reduces these errors to become less than 1 out of 100 administrated medication doses by improving healthcare professional education and clearer handwritten prescriptions...
September 4, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28869712/acute-oxygen-therapy-an-audit-of-prescribing-and-delivery-practices-in-a-tertiary-hospital-in-perth-western-australia
#15
Anam Kamran, Elisa Chia, Claire Tobin
BACKGROUND: Oxygen is a widely used drug in the hospital setting. However, international audits suggest that oxygen administration practices are often not compliant with prescribed standards. This can place patients at risk and cause serious adverse events. AIM: To analyse data related to recent practices of oxygen prescription and administration at Royal Perth Hospital (RPH), Western Australia. The results of this audit aim to guide further research on possible interventional studies implementing key solutions...
September 4, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28868960/e-pain-reporter-a-digital-pain-and-analgesic-diary-for-home-hospice-care
#16
Masako Mayahara, JoEllen Wilbur, Sean O'Mahony, Susan Breitenstein
Informal hospice caregivers play a key role in managing patients' pain at home, but lack of adherence to doctor-prescribed analgesic regimens and medication errors are significant barriers to truly effective pain management. A digital pain diary may improve caregiver management of pain at home; however, most digital pain tools available today were developed without input from patients or caregivers. Accordingly, the purpose of this study was to develop a digital pain application (1) for hospice caregivers to record patient pain and analgesic use and (2) for nurses to monitor administration of analgesics by caregivers...
January 1, 2017: Journal of Palliative Care
https://www.readbyqxmd.com/read/28858001/prescribing-errors-with-low-molecular-weight-heparins
#17
Marielle Slikkerveer, Afke van de Plas, Johanna H M Driessen, Robin Wijngaard, Frank de Vries, Renske Olie, Nathalie Meertens, Patricia van den Bemt
BACKGROUND: Low-molecular-weight heparins (LMWHs) are used in the prevention and treatment of venous thromboembolism (VTE). Bleeding is the primary major complication of LMWH therapy, which is associated with dose. The administration of appropriate dosages of LMWHs depends on the patient's risk of VTE, risk of bleeding, bodyweight, and renal function. Therefore, LMWH prescribing is prone to errors. However, no earlier study has explored the frequency of prescribing errors with LMWH. PURPOSE: The aim of the study was to determine the frequency and determinants of in-hospital LMWH-prescribing errors...
August 28, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28854919/adaption-implementation-and-evaluation-of-collaborative-service-improvements-in-the-testing-and-result-communication-process-in-primary-care-from-patient-and-staff-perspectives-a-qualitative-study
#18
Ian J Litchfield, Louise M Bentham, Richard J Lilford, Richard J McManus, Ann Hill, Sheila Greenfield
BACKGROUND: Increasing numbers of blood tests are being ordered in primary care settings and the swift and accurate communication of test results is central to providing high quality care. The process of testing and result communication is complex and reliant on the coordinated actions of care providers, external groups in laboratory and hospital settings, and patients. This fragmentation leaves it vulnerable to error and the need to improve an apparently fallible system is apparent. However, primary care is complex and does not necessarily adopt change in a linear and prescribed manner influenced by a range of factors relating to practice staff, patients and organisational factors...
August 30, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28852529/evaluating-insulin-information-provided-on-discharge-summaries-in-a-secondary-care-hospital-in-the-united-kingdom
#19
Amie Bain, Lois Nettleship, Sallianne Kavanagh, Zaheer-Ud-Din Babar
BACKGROUND: Prescribing errors at the time of hospital discharge are common and could potentially lead to avoidable patient harm, especially when they involve insulin, a high-risk medicine widely used for the treatment of diabetes mellitus. When information regarding insulin therapy is not sufficiently communicated to a patient's primary care provider, continuity of care for patients with diabetes may be compromised. The objectives of this study were to investigate the nature and prevalence of insulin-related medication discrepancies contained in hospital discharge summaries for patients with diabetes...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28838856/blood-transfusion-in-burn-patients-triggers-of-transfusion-in-a-referral-burn-center-in-iran
#20
S H Tavousi, A Ahmadabadi, A Sedaghat, M Khadem-Rezaiyan, Z Yaghoubi Moghaddam, M J Behrouzian, S Nemati, H Saghafi
OBJECTIVES: Blood and its derivatives are one of the most lifesaving products in the modern medicine practice. However, it is not an absolutely safe prescription. Many adverse effects such as infection, transfusion-related acute lung injury, immunosuppression, multi-organ dysfunction, acute respiratory syndrome, transfusion errors, transmission of infectious agents such as HIV, HBV, HCV are attributable to blood transfusion. The aim of this study was to describe how and when blood products were transfused in a referral burn center...
August 21, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
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