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Prescribing errors

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https://www.readbyqxmd.com/read/29145878/improving-readiness-for-recruitment-through-simulated-trial-activation-the-adjuvant-steroids-in-adults-with-pandemic-influenza-asap-trial
#1
Wei Shen Lim, Garry Meakin, Clare Brittain, Thomas Bewick, Lelia Duley
BACKGROUND: Research in public health emergencies requires trials to be set up in readiness for activation at short notice and in anticipation of limited timelines for patient recruitment. We conducted a simulated activation of a hibernating pandemic influenza clinical trial in order to test trial processes and to determine the value of such simulation in maintaining trial readiness. METHODS: The simulation involved the Nottingham Clinical Trials Unit, one participating hospital, one manufacturing unit and the Investigational Medicinal Product (IMP) supplier...
November 16, 2017: Trials
https://www.readbyqxmd.com/read/29142413/antiurolithiatic-potential-of-neeri-against-calcium-oxalate-stones-by-crystallization-inhibition-free-radicals-scavenging-and-nrk-52e-cell-protection-from-oxalate-injury
#2
Parveen Kumar Goyal, Santosh Kumar Verma, Anil Kumar Sharma
Background: Neeri is a well-established polyherbal formulation prescribed for renal stones by the physicians but has not been experimentally evaluated for its antiurolithiatic potential using cell-lines. Objective: This study is aimed to scientifically substantiate the antiurolithiatic effect of Neeri extract (NRE) through calcium oxalate (CaOx) crystallization inhibition, scavenging of free radicals, and protection of renal tubular epithelial NRK-52E cells from oxalate-induced injury...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29141618/what-do-australian-consumers-pharmacists-and-prescribers-think-about-documenting-indications-on-prescriptions-and-dispensed-medicines-labels-a-qualitative-study
#3
Mona Garada, Andrew J McLachlan, Gordon D Schiff, Elin C Lehnbom
BACKGROUND: Documenting the indication on prescriptions and dispensed medicines labels is not standard practice in Australia. However, previous studies that have focused on the content and design of dispensed medicines labels, have suggested including the indication as a safety measure. The aim of this study was to investigate the perspectives of Australian consumers, pharmacists and prescribers on documenting the indication on prescriptions and dispensed medicines labels. METHODS: Semi-structured interviews were conducted and mock-up of dispensed medicines labels were designed for participants...
November 15, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29138993/adverse-drug-events-and-medication-errors-in-african-hospitals-a-systematic-review
#4
REVIEW
Alemayehu B Mekonnen, Tariq M Alhawassi, Andrew J McLachlan, Jo-Anne E Brien
BACKGROUND: Medication errors and adverse drug events are universal problems contributing to patient harm but the magnitude of these problems in Africa remains unclear. OBJECTIVE: The objective of this study was to systematically investigate the literature on the extent of medication errors and adverse drug events, and the factors contributing to medication errors in African hospitals. METHODS: We searched PubMed, MEDLINE, EMBASE, Web of Science and Global Health databases from inception to 31 August, 2017 and hand searched the reference lists of included studies...
November 14, 2017: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/29131196/multi-element-direct-design-using-a-freeform-surface-for-a-compact-illumination-system
#5
Zhenfeng Zhuang, Phil Surman, Simon Thibault
An iterative optimization algorithm is introduced to address the surface iterative errors as well as source extension issues in a freeform illumination system for producing satisfactory illumination distribution. A unique two-parameter coordinate system is utilized to represent the emitted ray directions. Then, the direction vector for the incident rays, which propagate through several surfaces, is obtained using ray-tracing techniques. Based on the mapping between the incoming rays and a target grid, a freeform surface is generated as a good starting design...
November 10, 2017: Applied Optics
https://www.readbyqxmd.com/read/29130127/predictability-of-orthodontic-movement-with-orthodontic-aligners-a-retrospective-study
#6
Luca Lombardo, Angela Arreghini, Fabio Ramina, Luis T Huanca Ghislanzoni, Giuseppe Siciliani
BACKGROUND: The aim of this study was to evaluate the predictability of F22 aligners (Sweden & Martina, Due Carrare, Italy) in guiding teeth into the positions planned using digital orthodontic setup. METHODS: Sixteen adult patients (6 males and 10 females, mean age 28 years 7 months) were selected, and a total of 345 teeth were analysed. Pre-treatment, ideal post-treatment-as planned on digital setup-and real post-treatment models were analysed using VAM software (Vectra, Canfield Scientific, Fairfield, NJ, USA)...
November 13, 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/29127516/vision-and-visual-history-in-elite-near-elite-level-cricketers-and-rugby-league-players
#7
Brendan T Barrett, Jonathan C Flavell, Simon J Bennett, Alice G Cruickshank, Alex Mankowska, Julie M Harris, John G Buckley
BACKGROUND: The importance of optimal and/or superior vision for participation in high-level sports remains the subject of considerable clinical research interest. Here, we examine the vision and visual history of elite/near-elite cricketers and rugby-league players. METHODS: Stereoacuity (TNO), colour vision, and distance (with/without pinhole) and near visual acuity (VA) were measured in two cricket squads (elite/international-level, female, n = 16; near-elite, male, n = 23) and one professional rugby-league squad (male, n = 20)...
November 10, 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/29122210/strategies-to-increase-patient-safety-in-hemodialysis-application-of-the-modal-analysis-system-of-errors-and-effects-fema-system
#8
María Dolores Arenas Jiménez, Gabriel Ferre, Fernando Álvarez-Ude
BACKGROUND: Haemodialysis (HD) patients are a high-risk population group. For these patients, an error could have catastrophic consequences. Therefore, systems that ensure the safety of these patients in an environment with high technology and great interaction of the human factor is a requirement. OBJECTIVES: To show a systematic working approach, reproducible in any HD unit, which consists of recording the complications and errors that occurred during the HD session; defining which of those complications could be considered adverse event (AE), and therefore preventable; and carrying out a systematic analysis of them, as well as of underlying real or potential errors, evaluating their severity, frequency and detection; as well as establishing priorities for action (Failure Mode and Effects Analysis system [FMEA systems])...
November 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29117104/current-status-of-legislation-on-dietary-products-for-sportspeople-in-a-european-framework
#9
REVIEW
José Miguel Martínez-Sanz, Isabel Sospedra, Eduard Baladía, Laura Arranz, Rocío Ortiz-Moncada, Angel Gil-Izquierdo
The consumption of nutritional ergogenic aids is conditioned by laws/regulations, but standards/regulations vary between countries. The aim of this review is to explore legislative documents that regulate the use of nutritional ergogenic aids intended for sportspeople in a Spanish/European framework. A narrative review has been developed from official websites of Spanish (Spanish Agency of the Consumer, Food Safety, and Nutrition) and European (European Commission and European Food Safety Authority) bodies...
November 8, 2017: Nutrients
https://www.readbyqxmd.com/read/29114561/awareness-about-rational-use-of-medicines-among-fresh-bachelor-of-medicine-and-bachelor-of-surgery-graduates
#10
Vijaya Laxman Chaudhari, Smita N Mali, Amruta V Dawari, Tushar B Nishandar
CONTEXT: Fresh Bachelor of Medicine and Bachelor of Surgery graduates (FMGs) are responsible for the majority of prescription errors and irrational use of medicines. Little research has explored their knowledge on rational prescribing practices. AIMS: The present study aimed to evaluate the awareness of rational use of medicines (RUMs) among the FMGs. SETTINGS AND DESIGN: A multicentric, cross-sectional, and questionnaire-based study was conducted among 308 FMGs during the internship orientation program...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29109576/baseline-competency-assessment-of-pharmacists-prescribing-and-managing-vancomycin-therapy-in-the-regina-qu-appelle-health-region
#11
Kirsten Tangedal, Jennifer Bolt, Suzanne Len, Ali Bell
Background: Pharmacists in the Regina Qu'Appelle Health Region (RQHR), Saskatchewan, independently dose, monitor, and adjust vancomycin therapy. No framework exists for ongoing competency assessment of pharmacists. Objectives: The primary objective was to determine pharmacists' overall level of competency for all components of the vancomycin prescribing procedure. The secondary objectives were to determine competency for individual prescribing phases, to stratify overall competency in relation to pharmacist and patient factors, and to identify the 3 most frequent errors...
September 2017: Canadian Journal of Hospital Pharmacy
https://www.readbyqxmd.com/read/29103898/atmospheric-modeling-to-assess-wind-dependence-in-tracer-dilution-method-measurements-of-landfill-methane-emissions
#12
Diane M Taylor, Fotini K Chow, Madjid Delkash, Paul T Imhoff
The short-term temporal variability of landfill methane emissions is not well understood due to uncertainty in measurement methods. Significant variability is seen over short-term measurement campaigns with the tracer dilution method (TDM), but this variability may be due in part to measurement error rather than fluctuations in the actual landfill emissions. In this study, landfill methane emissions and TDM-measured emissions are simulated over a real landfill in Delaware, USA using the Weather Research and Forecasting model (WRF) for two emissions scenarios...
November 2, 2017: Waste Management
https://www.readbyqxmd.com/read/29099732/error-in-drugs-consumption-among-older-patients
#13
Yosefa Bar-Dayan, Thomas Shotashvily, Mona Boaz, Julio Wainstein
The cost effectiveness of generic drugs has promoted their use worldwide. However, the large variety of bioequivalent generic and brand-name drugs found in the marketplace increases the complexity and frequency of mistakes in drug consumption. This clinical study investigated the prevalence of various mistakes in drug consumption by patients using a hospital setting. This prospective clinical trial used a hospital setting to identify errors in drug consumption. Six hundred patients who were hospitalized for a minimum of 48 hours in the Internal Medicine Departments were checked at various time points...
November 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29095340/prescribing-errors-with-levetiracetam-oral-solution
#14
Ann Shastay
No abstract text is available yet for this article.
November 2017: Home Healthcare Now
https://www.readbyqxmd.com/read/29079061/adaptive-backstepping-h%C3%A2-tracking-control-with-prescribed-performance-for-internet-congestion
#15
Yang Liu, Xiaoping Liu, Yuanwei Jing, Shaowei Zhou
This paper extends the well-known control method, prescribed performance control (PPC), to network congestion control problems. An adaptive H∞ tracking problem for Transmission Control Protocol/Active Queue Management (TCP/AQM) system with external disturbance is studied. Firstly, a modified network model is given. And then, the model is changed to an equivalent error model by using error transformation. Next, to solve the network congestion problem, prescribed performance, backstepping technique, adaptive control and H∞ control are combined to design a congestion controller...
October 24, 2017: ISA Transactions
https://www.readbyqxmd.com/read/29076238/retrospective-review-of-ct-guided-intervertebral-disc-biopsies-performed-at-a-tertiary-referral-centre-for-suspected-osteodiscitis
#16
Kylie Lopes Floro, Wendy Munckhof, John Coucher
INTRODUCTION: Patients with osteodiscitis are often prescribed antibiotics prior to biopsy. There is controversy in the literature about whether antibiotic pre-treatment prior to CT-guided biopsy decreases the microbiological culture yield. Conclusions from previous studies are influenced by sample size error and selection bias. Our study, conducted in a large number of patients over a 10-year period, clarifies this issue so that best clinical practice is assured. METHODS: We performed a retrospective audit of the clinical, radiological and microbiological features of adult patients who underwent CT-guided biopsies for suspected osteodiscitis at a tertiary institution...
October 27, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29074078/the-impact-of-treatment-accuracy-on-proton-therapy-patient-selection-for-oropharyngeal-cancer-patients
#17
Tine Arts, Sebastiaan Breedveld, Martin A de Jong, Eleftheria Astreinidou, Lisa Tans, Fatma Keskin-Cambay, Augustinus D G Krol, Steven van de Water, Rik G Bijman, Mischa S Hoogeman
BACKGROUND AND PURPOSE: The impact of treatment accuracy on NTCP-based patient selection for proton therapy is currently unknown. This study investigates this impact for oropharyngeal cancer patients. MATERIALS AND METHODS: Data of 78 patients was used to automatically generate treatment plans for a simultaneously integrated boost prescribing 70 GyRBE/54.25 GyRBE in 35 fractions. IMRT treatment plans were generated with three different margins; intensity modulated proton therapy (IMPT) plans for five different setup and range robustness settings...
October 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29066355/response-to-correction-of-refractive-errors-and-hypoaccommodation-in-children-with-congenital-zika-syndrome
#18
Liana O Ventura, Linda Lawrence, Camila V Ventura, Gordon N Dutton, Polyana Marinho, Priscila F Ferro, Adriana L Gois, Natalia C Dias, Larissa Ventura, Cynthia A Moore, Lea Hyvärinen
PURPOSE: To describe the immediate response to correction of refractive errors and hypoaccommodation in children with congenital Zika syndrome (CZS). METHODS: Children born between May and December 2015 with a confirmed diagnosis of CZS and enrolled in a multidisciplinary early intervention program were included in this study. All children received a comprehensive ophthalmic examination, including dynamic retinoscopy and cycloplegic refraction. Children were prescribed their full correction if they met the criteria for refractive error, strabismus, accommodative dysfunction, and/or low vision...
October 21, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29062230/treatment-burden-clinical-outcomes-and-comorbidities-in-copd-an-examination-of-the-utility-of-medication-regimen-complexity-index-in-copd
#19
Netsanet A Negewo, Peter G Gibson, Peter Ab Wark, Jodie L Simpson, Vanessa M McDonald
BACKGROUND: COPD patients are often prescribed multiple medications for their respiratory disease and comorbidities. This can lead to complex medication regimens resulting in poor adherence, medication errors, and drug-drug interactions. The relationship between clinical outcomes and medication burden beyond medication count in COPD is largely unknown. OBJECTIVES: The aim of this study was to explore the relationships of medication burden in COPD with clinical outcomes, comorbidities, and multidimensional indices...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29042838/dose-banding-of-intravenous-piperacillin-tazobactam-in-pediatric-surgical-inpatients
#20
Indrajit S Karande, Zoy Goff, Jacqueline Kewley, Shailender Mehta, Thomas Snelling
BACKGROUND: Antimicrobial doses in children are often prescribed by using an individually calculated dose per weight (e.g., mg/kg) or based on body surface area. Dosing errors are the most commonly reported medication errors in children. A "dose-banding" strategy is frequently used for some over-the-counter drugs to prevent dosing errors. It could also lead to efficiencies by enabling batch preparation of intravenous (IV) medications in hospitals. OBJECTIVES: To evaluate whether use of dose-banding for IV piperacillin-tazobactam results in acceptable dose variation from standard practice of individualized prescription of 100 mg/kg in children...
September 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
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