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Therapeutic Recreation

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https://www.readbyqxmd.com/read/29786793/a-method-for-prostate-and-breast-cancer-cell-spheroid-cultures-using-gelatin-methacryloyl-based-hydrogels
#1
Christoph Meinert, Christina Theodoropoulos, Travis J Klein, Dietmar W Hutmacher, Daniela Loessner
Modern tissue engineering technologies have delivered tools to recreate a cell's naturally occurring niche in vitro and to investigate normal and pathological cell-cell and cell-niche interactions. Hydrogel biomaterials mimic crucial properties of native extracellular matrices, including mechanical support, cell adhesion sites and proteolytic degradability. As such, they are applied as 3D cell culture platforms to replicate tissue-like architectures observed in vivo, allowing physiologically relevant cell behaviors...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29786680/-the-comprehensive-evaluation-of-the-bioclimatic-comfort-at-the-territories-of-the-russian-far-east-with-reference-to-winter-time-recreational-activities-and-primary-wellness-tourism
#2
N M Pestereva, A F Khechumyan, N Vorozbit
BACKGROUND: in the framework of the current tendency toward the further development of the socio-economic sphere in the Russian Far East (RFE), the relevant investigations aimed at creating the comfortable conditions for recreational and touristic activities as well as for rehabilitative therapy of the local population acquire the increasingly greater importance. AIM: The objective of the present study was the comprehensive evaluation of the bioclimatic comfort at the territories of interest with special reference to winter-time recreational activities and primary wellness tourism...
May 21, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29781894/a-survey-of-american-psychiatrists-attitudes-toward-classic-hallucinogens
#3
Brian S Barnett, Willie O Siu, Harrison G Pope
Recent years have seen renewed interest and research about the use of hallucinogens as possible agents in the treatment of psychiatric disorders. However, we are unaware of studies assessing the current attitudes of American psychiatrists regarding hallucinogens. Therefore, we e-mailed surveys to 1000 members of the American Psychiatric Association-250 resident-fellows and 750 attending psychiatrists. The response rate was 32.4%. Respondents tended to perceive hallucinogens as potentially hazardous and appropriately illegal for recreational purposes...
May 17, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29781550/walking-gait-asymmetries-six-months-following-anterior-cruciate-ligament-reconstruction-predict-twelve-month-patient-reported-outcomes
#4
Brian Pietrosimone, J Troy Blackburn, Darin A Padua, Steven J Pfeiffer, Hope C Davis, Brittney A Luc-Harkey, Matthew S Harkey, Laura E Stanley, Barnett S Frank, R Alexander Creighton, Ganesh M Kamath, Jeffery T Spang
The study sought to determine the association between gait biomechanics (vertical ground reaction force [vGRF], vGRF loading rate [vGRF-LR]) collected six months following anterior cruciate ligament reconstruction (ACLR) with patient-reported outcomes at twelve months following ACLR. Walking gait mechanics and all subsections of the Knee Injury and Osteoarthritis Outcomes Score (KOOS) were collected at six and twelve months following ACLR, respectively, in 25 individuals with a unilateral ACLR. Peak vGRF and peak instantaneous vGRF-LR were extracted from the first 50% of the stance phase...
May 21, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29776724/outcomes-of-splinting-in-pediatric-mallet-finger
#5
James S Lin, Julie Balch Samora
PURPOSE: Excessive flexion at the distal interphalangeal (DIP) joint disrupts the extensor mechanism, leading to mallet finger injuries. The goal of management is to restore active DIP joint extension. We sought to learn which variables (treatment technique, injury type, time to presentation, adherence to treatment) affect clinical outcomes of pediatric mallet finger injuries. METHODS: A retrospective review was performed of patients who presented with mallet finger injuries during 2013 to 2017 at a large pediatric hospital...
May 15, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29767474/mesenchymal-stromal-cells-from-shwachman-diamond-syndrome-patients-fail-to-recreate-a-bone-marrow-niche-in-vivo-and-exhibit-impaired-angiogenesis
#6
Donatella Bardelli, Erica Dander, Cristina Bugarin, Claudia Cappuzzello, Alice Pievani, Grazia Fazio, Paolo Pierani, Paola Corti, Piero Farruggia, Carlo Dufour, Simone Cesaro, Marco Cipolli, Andrea Biondi, Giovanna D'Amico
Shwachman-Diamond syndrome (SDS) is a rare multi-organ recessive disease mainly characterised by pancreatic insufficiency, skeletal defects, short stature and bone marrow failure (BMF). As in many other BMF syndromes, SDS patients are predisposed to develop a number of haematopoietic malignancies, particularly myelodysplastic syndrome and acute myeloid leukaemia. However, the mechanism of cancer predisposition in SDS patients is only partially understood. In light of the emerging role of mesenchymal stromal cells (MSCs) in the regulation of bone marrow homeostasis, we assessed the ability of MSCs derived from SDS patients (SDS-MSCs) to recreate a functional bone marrow niche, taking advantage of a murine heterotopic MSC transplant model...
May 16, 2018: British Journal of Haematology
https://www.readbyqxmd.com/read/29760180/the-affective-and-neural-correlates-of-heroin-vs-cocaine-use-in-addiction-are-influenced-by-environmental-setting-but-in-opposite-directions
#7
Silvana De Pirro, Gaspare Galati, Luigi Pizzamiglio, Aldo Badiani
Previous studies have shown that individuals with heroin and cocaine addiction prefer to use these drugs in distinct settings: mostly at home in the case of heroin and mostly outside the home in the case of cocaine. Here we investigated whether the context would modulate the affective and neural responses to these drugs in a similar way. First, we used a novel emotional task to assess the affective state produced by heroin or cocaine in different settings, based on the recollections of male and female drug users...
May 14, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29755056/therapeutic-recreation-in-the-public-schools-a-community-partnership
#8
Frederick Green, Christopher Brown, Evelyn Gordon, Deborah Martin
BACKGROUND: In 2002, the University of Southern Mississippi's Therapeutic Recreation Program and the Hattiesburg (MS) Public School District's Department of Exceptional Children and Health Services formed a partnership that has lasted (off and on) for 15 years. METHODS: The partnership was formed based on a shared mission of education and training, and grew in depth based on reciprocated respect and support. RESULTS: Early collaborative efforts included simple programming efforts that provided health and educational benefits for the students with disabilities in the public schools and training for the future professionals in therapeutic recreation at the university...
2018: Progress in Community Health Partnerships: Research, Education, and Action
https://www.readbyqxmd.com/read/29749280/beyond-china-s-drug-century-yunnan-s-first-therapeutic-community-and-narratives-of-drug-treatment-and-mental-health-care
#9
Sandra Teresa Hyde
China is experiencing rapid cultural change and new forms of sociability that are accompanied by social problems and novel humanitarian interventions that have been formulated to address those problems. The pressure related to the rapid transformation of the countryside into mid-level cities has led to recreational drug-use as a means of escape. These illegal drugs have greased the wheels of what I call an affective biopolitics that has influenced Chinese citizens. Carlos Rojas argues that development in China results from the effects of discrete protocols, or practices that stem from tensions between capital and labor, governmentality and biopolitics, and nationalism and globalization...
January 1, 2018: Transcultural Psychiatry
https://www.readbyqxmd.com/read/29741426/yoga-therapy-in-the-german-healthcare-system
#10
Holger Cramer
An estimated 15.7 million Germans are currently practicing yoga or are at least interested in starting to practice, and they often perceive yoga as a therapeutic approach. From a healthcare system perspective, the situation is less clear. Here, yoga is only recognized as a recreational or preventive activity. When yoga teachers fulfill specific qualifications, their preventive yoga classes are covered by the statutory health insurances. Only those with additional qualifications in medicine or psychotherapy, however, can independently use and promote "yoga therapy...
May 9, 2018: International Journal of Yoga Therapy
https://www.readbyqxmd.com/read/29737043/bioreactors-for-cardiac-tissue-engineering
#11
REVIEW
Jesus Paez-Mayorga, Gustavo Hernández-Vargas, Guillermo U Ruiz-Esparza, Hafiz M N Iqbal, Xichi Wang, Yu Shrike Zhang, Roberto Parra-Saldivar, Ali Khademhosseini
The advances in biotechnology, biomechanics, and biomaterials can be used to develop organ models that aim to accurately emulate their natural counterparts. Heart disease, one of the leading causes of death in modern society, has attracted particular attention in the field of tissue engineering. To avoid incorrect prognosis of patients suffering from heart disease, or from adverse consequences of classical therapeutic approaches, as well as to address the shortage of heart donors, new solutions are urgently needed...
May 8, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29726054/gdnf-and-alcohol-use-disorder
#12
Segev Barak, Somayeh Ahmadiantehrani, Marian L Logrip, Dorit Ron
Glial cell line-derived neurotrophic factor (GDNF) has been extensively studied for its role in the development and maintenance of the midbrain dopaminergic system, although evidence suggests that GDNF also plays a role in drug and alcohol addiction. This review focuses on the unique actions of GDNF in the mechanisms that prevent the transition from recreational alcohol use to abuse. Specifically, we describe studies in rodents suggesting that alcohol acutely increases GDNF expression in the ventral tegmental area, which enables the activation of the mitogen-activated protein kinase signaling pathway and the gating of alcohol intake...
May 4, 2018: Addiction Biology
https://www.readbyqxmd.com/read/29724156/pulp-regeneration-concepts-for-non-vital-teeth-from-tissue-engineering-to-clinical-approaches
#13
Valérie Orti, Pierre-Yves Collart-Dutilleul, Sofía Silvia Piglionico, Orsolya Pall, Frédéric Cuisinier, Ivan Vladislavov Panayotov
Following the basis of tissue engineering (Cells - Scaffold - Bioactive molecules), regenerative endodontic has emerged as a new concept of dental treatment. Clinical procedures have been proposed by endodontic practitioners willing to promote regenerative therapy. Preserving pulp vitality was a first approach. Later procedures aimed to regenerate a vascularized pulp in necrotic root canals. However, there is still no protocol allowing an effective regeneration of necrotic pulp tissue either in immature or mature teeth...
May 4, 2018: Tissue Engineering. Part B, Reviews
https://www.readbyqxmd.com/read/29706358/the-role-of-cannabinoid-signaling-in-acute-and-chronic-kidney-diseases
#14
REVIEW
Federica Barutta, Graziella Bruno, Raffaella Mastrocola, Stefania Bellini, Gabriella Gruden
The endogenous cannabinoids anandamide and 2-arachidonoylglycerol bind to the cannabinoid receptors of type 1 and 2. These receptors are also the binding sites for exogenous, both natural and synthetic, cannabinoids that are used for recreation purposes. Until recently, cannabinoids and cannabinoid receptors have attracted little interest among nephrologists; however, a full endocannabinoid system (ECS) is present in the kidney and it has recently emerged as an important player in the pathogenesis of diabetic nephropathy, drug nephrotoxicity, and progressive chronic kidney disease...
April 26, 2018: Kidney International
https://www.readbyqxmd.com/read/29695077/role-of-bioreactor-technology-in-tissue-engineering-for-clinical-use-and-therapeutic-target-design
#15
REVIEW
Clare Selden, Barry Fuller
Micro and small bioreactors are well described for use in bioprocess development in pre-production manufacture, using ultra-scale down and microfluidic methodology. However, the use of bioreactors to understand normal and pathophysiology by definition must be very different, and the constraints of the physiological environment influence such bioreactor design. This review considers the key elements necessary to enable bioreactors to address three main areas associated with biological systems. All entail recreation of the in vivo cell niche as faithfully as possible, so that they may be used to study molecular and cellular changes in normal physiology, with a view to creating tissue-engineered grafts for clinical use; understanding the pathophysiology of disease at the molecular level; defining possible therapeutic targets; and enabling appropriate pharmaceutical testing on a truly representative organoid, thus enabling better drug design, and simultaneously creating the potential to reduce the numbers of animals in research...
April 24, 2018: Bioengineering
https://www.readbyqxmd.com/read/29694337/experimental-cerebral-hemispherectomy-in-rodent-models-a-systematic-review-of-current-literature
#16
Cezar Octavian Morosanu, Razvan Lucian Jurca, Larisa Simonca, Roxana Flavia Ilies, Remus Moldovan, Ioan Stefan Florian, Gabriela Adriana Filip
Cerebral hemispherectomy is a neurosurgical procedure that involves surgically removing one hemisphere of the brain, used as a therapeutic option in severe cases of intractable epilepsy. Several animal models have contributed to our understanding of the underlying neuromechanisms. The review was based on a PubMed search using the terms "hemispherectomy" and "mouse" or "rat" or "rodent", with no limitation of year of study or language. We identified a series of elements that were collected and analyzed that add up to our contemporary knowledge of this procedure...
2018: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/29690558/abuse-of-prescription-drugs-in-the-context-of-novel-psychoactive-substances-nps-a-systematic-review
#17
REVIEW
Fabrizio Schifano, Stefania Chiappini, John M Corkery, Amira Guirguis
Recently, a range of prescription and over-the-counter drugs have been reportedly used as Novel Psychoactive Substances (NPS), due to their potential for abuse resulting from their high dosage/idiosyncratic methods of self-administration. This paper provides a systematic review of the topic, focusing on a range of medications which have emerged as being used recreationally, either on their own or in combination with NPS. Among gabapentinoids, pregabalin may present with higher addictive liability levels than gabapentin, with pregabalin being mostly identified in the context of opioid, polydrug intake...
April 22, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29684297/is-medical-marijuana-legalisation-possible-in-poland
#18
Dorota Rogowska-Szadkowska, Julia Strumiło, Sławomir Chlabicz
OBJECTIVES: In some countries of the world it is legal to use plant-based marijuana for therapeutic purposes. When we had learned that 7,000 petitioners (including doctors) signed the petition to enable access to marijuana for patients in the Czech Republic, we decided to examine the knowledge about marijuana's medical properties among Polish medical students. METHODS: Anonymous questionnaire study was conducted on a group of 181 of students of the last (sixth) year of medical school...
March 2018: Central European Journal of Public Health
https://www.readbyqxmd.com/read/29680636/modifiable-risk-factors-for-prescription-medicine-sharing-behaviours
#19
Kebede Beyene, Trudi Aspden, Rob McNeill, Janie Sheridan
BACKGROUND: Prescription medicine sharing has been defined as giving one's own medicine to someone else (lending) or taking someone else's medicine (borrowing). Medicines can be shared for non-medical purposes (recreational sharing or drug abuse) or for their intended therapeutic benefits (non-recreational sharing, e.g. sharing antibiotics to self-treat); the latter is the focus of this research. Limited research evidence is available about modifiable risk factors for non-recreational medicine sharing and addressing this issue was the main aim of this research...
April 6, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29669296/a-twitter-based-survey-on-marijuana-concentrate-use
#20
Raminta Daniulaityte, Mussa Y Zatreh, Francois R Lamy, Ramzi W Nahhas, Silvia S Martins, Amit Sheth, Robert G Carlson
AIMS: The purpose of this paper is to analyze characteristics of marijuana concentrate users, describe patterns and reasons of use, and identify factors associated with daily use of concentrates among U.S.-based cannabis users recruited via a Twitter-based online survey. METHODS: An anonymous Web-based survey was conducted in June 2017 with 687 U.S.-based cannabis users recruited via Twitter-based ads. The survey included questions about state of residence, socio-demographic characteristics, and cannabis use including marijuana concentrates...
April 11, 2018: Drug and Alcohol Dependence
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