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https://www.readbyqxmd.com/read/28331367/knowledge-attitudes-and-behaviors-of-primary-health-care-nurses-and-midwives-in-breast-cancer-early-diagnosis-applications
#1
Aliye Bulut, Aziz Bulut
PURPOSE: The purpose of this research was to analyze the knowledge, attitudes and behaviors of the nurses and midwives about the early diagnosis of breast cancer. MATERIALS AND METHODS: This cross-sectional study was carried out at 9 family medical centers (FMCs) and 1 community health center (CHC) in Bingol; the population of this research consisted of 25 midwives and 38 nurses. The protocol for this study was approved by the regional ethics committee of Bingol University...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28290964/anabolic-adaptations-occur-in-conscripts-during-basic-military-training-despite-high-prevalence-of-vitamin-d-deficiency-and-decrease-in-iron-status
#2
Vahur Ööpik, Saima Timpmann, Leho Rips, Indrek Olveti, Kersti Kõiv, Martin Mooses, Hanno Mölder, Ahti Varblane, Hele-Reet Lille, Helena Gapeyeva
INTRODUCTION: In Estonian Defense Forces that are drawn up on the basis of the conscription model considerable numbers of young men are prematurely discharged from military service for medical reasons, but causes leading to premature dropout of conscripts have not been systematically studied. However, one of the factors involved could be relatively demanding physical training that starts at the beginning of military service in the form of basic military training (BMT). Cumulative training and nontraining stresses experienced by conscripts during BMT may exceed their physiological adaptability and increase the probability of becoming prematurely discharged...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28281157/climate-change-and-professional-responsibility-a-declaration-of-helsinki-for-engineers
#3
Rob Lawlor, Helen Morley
In this paper, we argue that the professional engineering institutions ought to develop a Declaration of Climate Action. Climate change is a serious global problem, and the majority of greenhouse gas emissions come from industries that are enabled by engineers and represented by the engineering professional institutions. If the professional institutions take seriously the claim that a profession should be self-regulating, with codes of ethics that go beyond mere obedience to the law, and if they take their own ethical codes seriously, recognising their responsibility to the public and to future generations (and also recognising a duty of "responsible leadership"), the professional institutions ought to develop a declaration for engineers, addressing climate change...
March 9, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28280304/factors-associated-with-preoperative-anxiety-levels-of-turkish-surgical-patients-from-a-single-center-in-ankara
#4
Ezgi Erkilic, Elvin Kesimci, Cem Soykut, Cihan Doger, Tülin Gumus, Orhan Kanbak
BACKGROUND: Preoperative anxiety and stress are undoubtedly a difficult experience in patients undergoing elective surgery. These unpleasant sensations depend on several factors. The objective of this study was to evaluate the preoperative anxiety levels in a sample of Turkish population, as well as the underlying causes using the Spielberger State-Trait Anxiety Inventory (STAI anxiety) scale. METHODS: The study was conducted according to the Declaration of Helsinki and was approved by the local ethical committee...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28266774/issue-information-declaration-of-helsinki
#5
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28260450/questionnaire-on-brain-death-and-organ-procurement
#6
Saleh Hammad, Manal Alnammourah, Farah Almahmoud, Mais Fawzi, Abdel-Hadi Breizat
OBJECTIVES: The subject of organs for transplant after brain death raises many concerns, including definition and timing of death, how to permit human organ transplant, and the idea of paying for organs. Many ethical concerns are raised regarding regulations and procedures for organ transplant in developing countries. These include where and how to obtain organs and the concept of justice in organ distribution. MATERIALS AND METHODS: We administered 2682 questionnaires to 628 men and 2054 women over 24 months (range, 18 to 70 years old)...
February 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28260347/adhd-and-enuresis-a-study-about-effectiveness-of-treatment-with-methylphenidate-or-desmopressin-in-a-pediatric-population
#7
Pietro Ferrara, Valeria Sannicandro, Francesca Ianniello, Enrica Quattrocchi, Annamaria Sbordone, Tommasangelo Petitti, Paolo Mariotti
BACKGROUND: To evaluate the effectiveness of treatment with methylphenidate or desmopressin (dDAVP) in patients with comorbid ADHD and enuresis. METHODS: We enrolled 103 patients affected by ADHD and 125 patients with monosymptomatic nocturnal enuresis (NE). Data were collected between January 2014 and December 2015. The study was carried out in compliance with the Helsinki Declaration. RESULTS: About children with ADHD, 9/103 (8,7%) were also suffering from NE; of those 8/9 followed treatment with methylphenidate and cognitive behavioral therapy...
March 3, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28245293/protective-effect-of-1%C3%AE-25-dihydroxyvitamin-d3-on-effector-cd4-t-cell-induced-injury-in-human-renal-proximal-tubular-epithelial-cells
#8
Byung Ha Chung, Bo-Mi Kim, Kyoung Chan Doh, Mi-La Cho, Kyoung Woon Kim, Chul Woo Yang
BACKGROUND: The aim of this study was to investigate the protective effect of 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] on effector CD4+ T cells or on inflammatory cytokine-induced injury in human renal proximal tubular epithelial cells (HRPTEpiC). METHODS: First, we investigated the effect of 1,25(OH)2D3 on CD4+ T cell proliferation. Second, we examined the effect of 1,25(OH)2D3 on inflammatory cytokine secretion or fibrosis in HRPTEpiC induced by inflammatory cytokines or activated CD4+ T cells using ELISA and real-time PCR...
2017: PloS One
https://www.readbyqxmd.com/read/28219961/protocol-for-the-development-of-a-core-domain-set-for-hidradenitis-suppurativa-trial-outcomes
#9
Linnea Thorlacius, John R Ingram, Amit Garg, Bente Villumsen, Solveig Esmann, Joslyn S Kirby, Alice B Gottlieb, Joseph F Merola, Robert Dellavalle, Robin Christensen, Gregor B E Jemec
INTRODUCTION: Randomised controlled trials (RCTs) should have well-defined primary and secondary outcomes to answer questions generated by the main hypotheses. However, for the chronic, inflammatory skin disease hidradenitis suppurativa (HS), the reported outcome measures are numerous and diverse. A recent systematic review found a total of 30 outcome measure instruments in 12 RCTs. This use of a broad range of outcome measures can increase difficulties in interpretation and comparison of results and may potentially obstruct appropriate evidence synthesis by causing reporting bias...
February 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28214788/authorship-criteria-and-reporting-of-ethical-compliance-in-indian-biomedical-journals
#10
Pravin Bolshete
The "instructions to authors" of a total of 55 PubMed/MEDLINE indexed Indian biomedical journals were evaluated to assess the authorship criteria and guidance on reporting of research ethics including incorporation of recent updates. Thirty-seven (67.3%) journals recommended the ICMJE guidelines for manuscript preparation. Thirty-two of 55 (58.2%) journals defined authorship; only two journals defined authorship as per the latest (2013) ICMJE criteria. The journals' recommendations which indicated ethical compliance in articles were - the conduct of a study in accordance with the Declaration of Helsinki(n=39); ethical approval (n=37); consent (n=26); assent (n=10); and consent for identifiable information (n=31)...
February 1, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28160317/issue-information-declaration-of-helsinki
#11
(no author information available yet)
No abstract text is available yet for this article.
February 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28132008/compensatory-changes-in-energy-balance-during-dapagliflozin-treatment-in-type-2-diabetes-mellitus-a-randomised-double-blind-placebo-controlled-cross-over-trial-energize-study-protocol
#12
Surya Panicker Rajeev, Victoria S Sprung, Carl Roberts, Jo A Harrold, Jason C G Halford, Andrej Stancak, Emma J Boyland, Graham J Kemp, Daniel J Cuthbertson, John P H Wilding
INTRODUCTION: Sodium glucose cotransporter 2 (SGLT2) inhibitors are effective blood-glucose-lowering medications with beneficial effects on body weight in patients with type 2 diabetes mellitus (T2DM). However, observed weight loss is less than that predicted from quantified glycosuria, suggesting a compensatory increase in energy intake or a decrease in energy expenditure. Studies using dual-energy X-ray absorptiometry (DEXA) have suggested most body weight change is due to loss of adipose tissue, but organ-specific changes in fat content (eg, liver, skeletal muscle) have not been determined...
January 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28099352/acute-pancreatitis-in-patients-with-pancreatic-cancer-timing-of-surgery-and-survival-duration
#13
Shaojun Li, Bole Tian
Acute pancreatitis (AP) is a rare manifestation of pancreatic cancer (PC). The relationship between AP and PC remains less distinct.From January 2009 to November 2015, 47consecutive patients with PC who presented with AP were reviewed for this study. Clinical features, clinicopathologic variables, postoperative complications, and follow-up evaluations of patients were documented in detail from our database. In order to identify cutoff threshold time for surgery, receiver operating curve (ROC) was built according to patients with or without postoperative complications...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28096255/sheppheartcabg-trial-comprehensive-early-rehabilitation-after-coronary-artery-bypass-grafting-a-protocol-for-a-randomised-clinical-trial
#14
Ida Elisabeth Højskov, Philip Moons, Niels Viggo Hansen, Søren La Cour, Peter Skov Olsen, Christian Gluud, Per Winkel, Jane Lindschou, Lau Caspar Thygesen, Ingrid Egerod, Selina Kikkenborg Berg
INTRODUCTION: Patients undergoing coronary artery bypass graft surgery often experience a range of symptoms. Studies indicate that non-pharmacological interventions such as exercise training and psychoeducation have a positive physiological and psychological effect in early outpatient rehabilitation. The SheppHeartCABG trial will investigate the effect of early comprehensive rehabilitation in early phase rehabilitation versus usual care. The aim of this paper is to present the protocol for the SheppHeartCABG trial...
January 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28089141/stable-emulsion-se-alone-is-an-effective-adjuvant-for-a-recombinant-baculovirus-expressed-h5-influenza-vaccine-in-healthy-adults-a-phase-2-trial
#15
John J Treanor, Laurence Chu, Brandon Essink, Derek Muse, Hana M El Sahly, Ruvim Izikson, Karen L Goldenthal, Peter Patriarca, Lisa M Dunkle
BACKGROUND: Influenza A viruses of the H5 subtype have been identified as important targets for development of vaccines. Achievement of potentially protective antibody responses against pandemic strains has usually required the use of adjuvants. OBJECTIVES: We evaluated a candidate A/Indonesia/05/2005 (H5) vaccine generated by baculovirus expression of recombinant hemagglutinin (HA) protein with or without stable emulsion (SE) as an adjuvant. METHODS: Healthy subjects 18-49years old were randomized (1:1:1:1) to receive two doses of rHA at 7...
February 7, 2017: Vaccine
https://www.readbyqxmd.com/read/28079801/acute-necrotizing-retinal-vasculitis-as-onset-of-systemic-lupus-erythematosus-a-case-report
#16
Simeon Monov, Ruska Hristova, Rositza Dacheva, Reni Toncheva, Russka Shumnalieva, Viara Shoumnalieva-Ivanova, Daniela Monova
RATIONALE: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by autoantibody production, complement activation, and deposition of immune complexes in tissues and organs. SLE can involve any region of the visual system. Although ocular manifestations are not part of the classification criteria for SLE, they can be observed in up to one-third of the patients with SLE. They are rarely reported at the time of disease onset. Retinal vasculitis is usually associated with active generalized disease...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28073727/psychosocial-vulnerability-and-hiv-aids-epidemiological-situation-among-people-with-hearing-disabilities-in-four-towns-in-cameroon
#17
C P Mboua, A Touko
The scientific literature about disabled people has stressed their high exposure to social exclusion and marginalization, linked to ways of thinking and representations about them. In the area of HIV/AIDS, this marginalization, which results in higher levels of self-stigmatization and especially in inequalities in prevention, continues to put disabled people at high risk of HIV infection. The current study, conducted with a socioepidemiological and behavioral approach, included 317 people with hearing disabilities, recruited through purposive sampling combined with a snowball approach...
November 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28073189/relationship-between-lower-urinary-tract-symptoms-and-inguinal-hernia
#18
Aykut Buğra Sentürk, Musa Ekici, Ibrahim Tayfun Sahiner, Tuncay Tas, Basri Cakiroglu
AIM: To determine the relationship between inguinal hernia (and inguinal hernia subtypes) and low urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH), that could be more common than we think. METHOD: The study was designed retrospectively and was done in accordance with the principles of the Declaration of Helsinki, including 100 patients aged > 50 years that were divided into 2 groups: patients with BPH (BPH group) and patients with BPH and inguinal hernia (BPH-IH group 2)...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28063975/surveying-opinions-of-149-registrants-to-the-research-registry-awareness-of-and-attitudes-towards-research-registration
#19
Riaz A Agha, Daniyal J Jafree, Martinique Vella-Baldacchino, Christopher Limb, Ter-Er Kusu-Orkar, Mirabel C Millip, Alexander J Fowler
BACKGROUND: Research registration is an important ethical principle in the Declaration of Helsinki, however, progress to increase registration has been slow. Understanding the attitudes of users towards registries may provide insights into increase research registration. In this survey-based study, we sought to gain insight from users of a single global research registry, the Research Registry(®) (www.researchregistry.com). METHODS: A Google Forms survey was created and emailed to all users of the Research Registry(®) (n = 1432)...
January 5, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28060427/in-defense-of-a-social-value-requirement-for-clinical-research
#20
David Wendler, Annette Rid
Many guidelines and commentators endorse the view that clinical research is ethically acceptable only when it has social value, in the sense of collecting data which might be used to improve health. A version of this social value requirement is included in the Declaration of Helsinki and the Nuremberg Code, and is codified in many national research regulations. At the same time, there have been no systematic analyses of why social value is an ethical requirement for clinical research. Recognizing this gap in the literature, recent articles by Alan Wertheimer and David Resnik argue that the extant justifications for the social value requirement are unpersuasive...
February 2017: Bioethics
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