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https://www.readbyqxmd.com/read/29458314/a-blended-learning-programme-regarding-professional-ethics-in-physiotherapy-students
#1
Marta Aguilar-Rodríguez, Elena Marques-Sule, Pilar Serra-Añó, Gemma Victoria Espí-López, Lirios Dueñas-Moscardó, Sofía Pérez-Alenda
BACKGROUND: In the university context, assessing students' attitude, knowledge and opinions when applying an innovative methodological approach to teach professional ethics becomes fundamental to know if the used approach is enough motivating for students. RESEARCH OBJECTIVE: To assess the effect of a blended-learning model, based on professional ethics and related to clinical practices, on physiotherapy students' attitude, knowledge and opinions towards learning professional ethics...
January 1, 2018: Nursing Ethics
https://www.readbyqxmd.com/read/29436569/knowledge-attitudes-practices-and-perceptions-of-clinicians-towards-conducting-clinical-trials-in-an-academic-tertiary-care-center
#2
Mohamad A Al-Tannir, Hind M Katan, Ahmad H Al-Badr, Mostafa M Al-Tannir, Amani K Abu-Shaheen
To investigate the knowledge, attitudes practices and perceptions of clinicians concerning the conducting of clinical trials (CTs).  Methods: A cross-sectional study was conducted on clinicians at King Fahad Medical City, Riyadh, Saudi Arabia. Data were collected using a self-administered questionnaire which divided into 5 sections: Section 1 covered respondents' demographics. The other 4 sections explored respondents' knowledge, attitudes, perceptions and practice towards conducting CTs.  Results: A total of 316 clinicians completed the questionnaire...
February 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29431915/issue-information-declaration-of-helsinki
#3
(no author information available yet)
No abstract text is available yet for this article.
February 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29422881/encouragement-induced-real-world-upper-limb-use-after-stroke-by-a-tracking-and-feedback-device-a-study-protocol-for-a-multi-center-assessor-blinded-randomized-controlled-trial
#4
Jeremia P O Held, Andreas R Luft, Janne M Veerbeek
Introduction: Retraining the paretic upper limb after stroke should be intense and specific to be effective. Hence, the best training is daily life use, which is often limited by motivation and effort. Tracking and feedback technology have the potential to encourage self-administered, context-specific training of upper limb use in the patients' home environment. The aim of this study is to investigate post-intervention and long-term effects of a wrist-worn activity tracking device providing multimodal feedback on daily arm use in hemiparetic subjects beyond 3 months post-stroke...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29419680/mir-664a-3p-expression-in-patients-with-obstructive-sleep-apnea-a-potential-marker-of-atherosclerosis
#5
Kun Li, Zhiting Chen, Yanwen Qin, Yongxiang Wei
The early prediction of atherosclerosis (AS) is important in the management of obstructive sleep apnea patients (OSA). MicroRNA (miRNA) plays a vital role in the evolution of OSA and AS. Its differential expression may therefore serve as a diagnostic and prognostic biomarker of AS in OSA. The aim of this study was to identify specific serum miRNAs that could serve as a novel screening signature of AS in OSA patients. The specificity and sensitivity of these miRNAs in the early diagnosis of AS in OSA patients were then determined...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29404298/clinicopathological-and-molecular-epidemiological-study-of-lung-cancer-patients-seen-at-a-tertiary-care-hospital-in-northern-india
#6
Randeep Singh, Nitesh Rohtagi
Aims: The primary objective of this study was to estimate the clinicopathological and molecular profile of lung cancer patients along with the evaluation of their clinical characteristics at a tertiary care hospital in Northern India. Subjects and Methods: A total of 421 patients with lung cancer histology who were treated at Max Super Speciality Hospitals were included in the study. The study protocol conforms to the ethical guidelines of the 1975 Declaration of Helsinki and permission was obtained from the Ethics Committee before the start of the study...
October 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29391385/the-nice-gut-trial-protocol-a-randomised-placebo-controlled-trial-of-oral-nitazoxanide-for-the-empiric-treatment-of-acute-gastroenteritis-among-australian-aboriginal-children
#7
Claire S Waddington, Charlie McLeod, Peter Morris, Asha Bowen, Mark Naunton, Jonathan Carapetis, Keith Grimwood, Roy Robins-Browne, Carl D Kirkwood, Robert Baird, David Green, Ross Andrews, Deborah Fearon, Joshua Francis, Julie A Marsh, Thomas Snelling
INTRODUCTION: Diarrhoeal disease is the second leading cause of death in children under 5 years globally, killing 525 000 annually. Australian Aboriginal and Torres Strait Islander (hereafter Aboriginal) children suffer a high burden of disease. Randomised trials in other populations suggest nitazoxanide accelerates recovery for children with Giardia, amoebiasis, Cryptosporidium, Rotavirus and Norovirus gastroenteritis, as well as in cases where no enteropathogens are found. METHODS AND ANALYSIS: This double blind, 1:1 randomised, placebo controlled trial is investigating the impact of oral nitazoxanide on acute gastroenteritis in hospitalised Australian Aboriginal children aged 3 months to <5 years...
February 1, 2018: BMJ Open
https://www.readbyqxmd.com/read/29388903/in-vivo-pet-assay-of-tumor-glutamine-flux-and-metabolism-in-human-trial-of-18f-2s-4r-4-fluoroglutamine
#8
Mark P S Dunphy, James J Harding, Sriram Venneti, Hanwen Zhang, Eva M Burnazi, Jacqueline Bromberg, Antonio M Omuro, James J Hsieh, Ingo K Mellinghoff, Kevin Staton, Christina Pressl, Bradley J Beattie, Pat B Zanzonico, John F Gerecitano, David P Kelsen, Wolfgang Weber, Serge K Lyashchenko, Hank F Kung, Jason S Lewis
Purpose To assess the clinical safety, pharmacokinetics, and tumor imaging characteristics of fluorine 18-(2S,4R)-4-fluoroglutamine (FGln), a glutamine analog radiologic imaging agent. Materials and Methods This study was approved by the institutional review board and conducted under a U.S. Food and Drug Administration-approved Investigational New Drug application in accordance with the Helsinki Declaration and the Health Insurance Portability and Accountability Act. All patients provided written informed consent...
January 31, 2018: Radiology
https://www.readbyqxmd.com/read/29384978/efficacy-and-safety-of-autologous-peripheral-blood-stem-cell-transplantation-for-philadelphia-chromosome-positive-acute-lymphoblastic-leukemia-a-study-protocol-for-a-multicenter-exploratory-prospective-study-auto-ph17-study
#9
Satoshi Nishiwaki, Isamu Sugiura, Yasuhiko Miyata, Shigeki Saito, Masashi Sawa, Tetsuya Nishida, Koichi Miyamura, Yachiyo Kuwatsuka, Akio Kohno, Masaaki Yuge, Masanobu Kasai, Hiroatsu Iida, Shingo Kurahashi, Masahide Osaki, Tatsunori Goto, Seitaro Terakura, Makoto Murata, Hiroyoshi Nishikawa, Hitoshi Kiyoi
INTRODUCTION: The prognosis of Philadelphia chromosome positive acute lymphoblastic leukemia (Ph + ALL) has been dramatically improved since the introduction of tyrosine kinase inhibitors (TKIs). Although allogeneic hematopoietic cell transplantation (allo-HCT) is a major treatment option, the role of autologous peripheral blood stem cell transplantation (auto-PBSCT) has been reconsidered, especially in patients who achieved early molecular remission. METHODS AND ANALYSIS: This is a multicenter exploratory study for Ph + ALL patients aged between 55 and 70 years who achieved complete molecular remission within 3 cycles of chemotherapy...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29371283/clinical-features-antimicrobial-susceptibility-patterns-and-genomics-of-bacteria-causing-neonatal-sepsis-in-a-children-s-hospital-in-vietnam-protocol-for-a-prospective-observational-study
#10
Nguyen Duc Toan, Thomas C Darton, Christine J Boinett, James I Campbell, Abhilasha Karkey, Evelyne Kestelyn, Le Quoc Thinh, Nguyen Kien Mau, Pham Thi Thanh Tam, Le Nguyen Thanh Nhan, Ngo Ngoc Quang Minh, Cam Ngoc Phuong, Nguyen Thanh Hung, Ngo Minh Xuan, Tang Chi Thuong, Stephen Baker
INTRODUCTION: The clinical syndrome of neonatal sepsis, comprising signs of infection, septic shock and organ dysfunction in infants ≤4 weeks of age, is a frequent sequel to bloodstream infection and mandates urgent antimicrobial therapy. Bacterial characterisation and antimicrobial susceptibility testing is vital for ensuring appropriate therapy, as high rates of antimicrobial resistance (AMR), especially in low-income and middle-income countries, may adversely affect outcome. Ho Chi Minh City (HCMC) in Vietnam is a rapidly expanding city in Southeast Asia with a current population of almost 8 million...
January 24, 2018: BMJ Open
https://www.readbyqxmd.com/read/29369134/posttraumatic-stress-depressive-emotions-and-satisfaction-with-life-after-a-road-traffic-accident
#11
Panagiota Copanitsanou, Evagelos Drakoutos, Vasileios Kechagias
BACKGROUND: The psychological response of injured people after traffic accidents includes stress and depression. PURPOSE: To assess orthopaedic patients' stress, depression, and satisfaction with life after traffic accidents in Greece. METHODS: Descriptive, longitudinal, correlational study. Patients' background factors, injury severity, scores on the Impact of Events Scale-Revised (IES-R), the Center for Epidemiologic Studies Depression (CES-D) Scale, and the Satisfaction With Life Quality (SWLQ) Scale were recorded...
January 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29362269/plenadrema-effect-of-dual-release-versus-conventional-hydrocortisone-on-fatigue-measured-by-ecological-momentary-assessments-a-study-protocol-for-an-open-label-switch-pilot-study
#12
Victor Brun Boesen, Thea Christoffersen, Torquil Watt, Stina Willemoes Borresen, Marianne Klose, Ulla Feldt-Rasmussen
INTRODUCTION: Patients with adrenal insufficiency have impaired health-related quality of life (QoL). The dual-release hydrocortisone preparation, Plenadren, has been developed to mimic the physiological cortisol release more closely than conventional hydrocortisone treatment. Plenadren has been shown to improve QoL, in particular fatigue, in patients with primary adrenal insufficiency. However, the effect has not been investigated in patients with secondary adrenal insufficiency; furthermore, no study has taken the diurnal variation of fatigue into account...
January 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/29362244/impact-of-early-palliative-care-on-overall-survival-of-patients-with-metastatic-upper-gastrointestinal-cancers-treated-with-first-line-chemotherapy-a-randomised-phase-iii-trial
#13
Emilie Hutt, Arlette Da Silva, Emilie Bogart, Sara Le Lay-Diomande, Diane Pannier, Stéphanie Delaine-Clisant, Marie-Cécile Le Deley, Antoine Adenis
INTRODUCTION: Palliative care (PC) has usually been offered at the end-of-life stage, although the WHO recommends providing PC as early as possible in the course of the disease. A recent study has shown that early PC (EPC) provides a more meaningful effect on quality of life and, surprisingly, on overall survival (OS) than standard treatment for patients with metastatic lung cancer. Whether EPC benefits also apply to patients with metastatic upper gastrointestinal (GI) cancers is unknown...
January 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/29346005/ethical-issues-in-social-media-research-for-public-health
#14
Ruth F Hunter, Aisling Gough, Niamh O'Kane, Gary McKeown, Aine Fitzpatrick, Tom Walker, Michelle McKinley, Mandy Lee, Frank Kee
Social media (SM) offer huge potential for public health research, serving as a vehicle for surveillance, delivery of health interventions, recruitment to trials, collection of data, and dissemination. However, the networked nature of the data means they are riddled with ethical challenges, and no clear consensus has emerged as to the ethical handling of such data. This article outlines the key ethical concerns for public health researchers using SM and discusses how these concerns might best be addressed. Key issues discussed include privacy; anonymity and confidentiality; authenticity; the rapidly changing SM environment; informed consent; recruitment, voluntary participation, and sampling; minimizing harm; and data security and management...
January 18, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29341309/issue-information-declaration-of-helsinki
#15
(no author information available yet)
No abstract text is available yet for this article.
January 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29317417/patients-and-therapists-experiences-with-a-new-treatment-programme-for-eating-disorders-that-combines-physical-exercise-and-dietary-therapy-the-ped-t-trial-a-qualitative-study-protocol
#16
Gunn Pettersen, Jan H Rosenvinge, Maria Bakland, Rolf Wynn, Therese Fostervold Mathisen, Jorunn Sundgot-Borgen
INTRODUCTION: Women with bulimia nervosa and binge eating disorder often suffer for many years before they seek professional help. Evidence-based treatments like cognitive-behavioural therapy (CBT) might be poorly accessible, and about 50% of those who receive CBT respond to it. Such outcome may reflect the heterogeneous nature of eating disorders, and addressing this heterogeneity calls for expanding the portfolio of treatment options. In particular, it is important to explore such options' acceptability, tolerability and affordability expressed through experiences with the treatment...
January 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29314333/programmed-cell-death-1-blockade-induced-cutaneous-sarcoid-like-epithelioid-granulomas-in-advanced-melanoma-a-case-report
#17
T Ogawa, Y Ishitsuka, K Iwamoto, H Koguchi-Yoshioka, R Tanaka, R Watanabe, Y Fujisawa, M Fujimoto
Sarcoidosis is a chronic, systemic inflammatory disorder of unknown etiology that is characterized by the formation of noncaseating granuloma in affected organs, most commonly the lung.1 In pulmonary sarcoidosis patients, the T helper 1 (Th1) cytokine profile of CD4+ as well as CD8+ T cells was demonstrated in bronchoalveolar lavage fluid.2 However, there has been no detailed description of a lymphocyte profile in cutaneous sarcoid-like epithelioid granulomas. Here, we report a case of sarcoid-like epithelioid granulomas induced by nivolumab in a patient with advanced melanoma and we performed functional lymphocyte analysis of the granuloma lesions...
January 5, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29247084/protocol-of-a-single-group-prospective-observational-study-on-the-diagnostic-value-of-3t-susceptibility-weighted-mri-of-nigrosome-1-in-patients-with-parkinsonian-symptoms-the-n3ipd-study-nigrosomal-iron-imaging-in-parkinson-s-disease
#18
Stefan T Schwarz, Yue Xing, Saadnah Naidu, Jim Birchall, Rob Skelly, Alan Perkins, Jonathan Evans, Gill Sare, Antonio Martin-Bastida, Nin Bajaj, Penny Gowland, Paola Piccini, Dorothee P Auer
INTRODUCTION: Parkinson's disease (PD) is the most common movement disorder in the elderly and is characterised clinically by bradykinesia, tremor and rigidity. Diagnosing Parkinson's can be difficult especially in the early stages. High-resolution nigrosome MRI offers promising diagnostic accuracy of patients with established clinical symptoms; however, it is unclear whether this may help to establish the diagnosis in the early stages of PD, when there is diagnostic uncertainty. In this scenario, a single photon emission CT scan using a radioactive dopamine transporter ligand can help to establish the diagnosis, or clinical follow-up may eventually clarify the diagnosis...
December 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29244252/issue-information-declaration-of-helsinki
#19
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29222884/development-and-evaluation-of-nutritional-sensory-and-glycemic-properties-of-finger-millet-eleusine-coracana-l-based-food-products
#20
Shanmugam Shobana, Ravi Poovizhi Selvi, Vasudevan Kavitha, Nagamuthu Gayathri, Gunasekaran Geetha, Rajagopal Gayathri, Parthasarthy Vijayalakshmi, K Kandappa Gounder Balasubramaniam, Vaidya Ruchi, Vasudevan Sudha, Ranjit Mohan Anjana, Ranjit Unnikrishnan, Nagappa Gurusiddappa Malleshi, C Jk Henry, Kamala Krishnaswamy, Viswanathan Mohan
BACKGROUND AND OBJECTIVES: Finger millet (Eleusine coracana L.) (FM) is rich in dietary fibre and is therefore expected to elicit a lower glycemic response compared to other grains. However, there is little data on the glycemic properties of FM-based products. We evaluated the nutritional, sensory and glycemic properties of decorticated millet with lower polish (DFM-LDP), flakes (FMF), vermicelli (FMV) and extruded snack (FMES) (both FMV and FMES with 7-8% added soluble fibre). METHODS AND STUDY DESIGN: The nutrient contents of the FM products were evaluated by standard AOAC (Association of Official Analytical Chemists) and AACC (American Association of Cereal Chemists) methods...
2018: Asia Pacific Journal of Clinical Nutrition
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