keyword
MENU ▼
Read by QxMD icon Read
search

Hepatitis, non-A, Non-B

keyword
https://www.readbyqxmd.com/read/27932130/acute-liver-failure-caused-by-primary-non-hodgkin-s-lymphoma-of-the-liver
#1
L Romacho López, F J León Díaz, B Sánchez Pérez, J A Pérez Daga, J L Fernández Aguilar, M C Montiel Casado, J M Aranda Narváez, M A Suárez Muñoz, J Santoyo Santoyo
INTRODUCTION: Acute liver failure (ALF) is a rare syndrome involving maximum liver dysfunction. This disease is characterized by a less than 26-week history of coagulopathy (INR ≥1.5) and hepatic encephalopathy and generally occurs in patients without any previously known disease. METHODS: We report the case of a healthy 25-year-old subject who presented with fulminant liver failure caused by a primary non-Hodgkin's lymphoma of the liver that required emergency liver transplantation...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27931582/liver-transplantation-for-hepatitis-b-in-early-adulthood-analysis-of-the-united-network-for-organ-sharing-database
#2
G Rifai, A Anani, I A Hanouneh, B Mohamad, A Matloob, R Lopez, N N Zein, N Alkhouri
BACKGROUND: Chronic hepatitis B virus (HBV) infection has a mild course in most children that may delay initiation of treatment even when indicated. Unfortunately, a small number of cases can progress rapidly to cirrhosis, which may require liver transplantation (LT) in early adulthood. The aim of this study was to assess the characteristics of HBV-positive young adults who received LT and to evaluate post-transplant outcomes including patient and graft survival and differences between pre- and post-implementation of Model for End-stage Liver Disease (MELD) prioritization...
December 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27931107/a-diffusely-enlarged-pancreas-the-un-usual-suspect
#3
Pedro Magalhães-Costa, Maria José Brito, Pedro Pinto-Marques
An 81-years-old female presented with obstructive jaundice and a non-specific clinical picture of nausea and appetite loss. Labs demonstrated a conjugated hyperbilirrubinemia (7.7 mg/dL), increased aspartate aminotransferase and alanine aminotransferase (10xULN and 8xULN, respectively), increased lactate dehydrogenase (10xULN) and serum lipase (3xULN). CA 19.9 was 342 U/mL (Ref value < 37 U/mL). There was no evidence of peripheral lymphadenopathy or hepatosplenomegaly. Imaging (Figure 1A and 1B) revealed a marked homogeneous enlargement of the pancreas (without any well-defined mass), dilation of the extra and intra-hepatic bile ducts and ascites...
December 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27930871/hepatitis-b-virus-infection-status-is-more-prevalent-in-patients-with-type-2-diabetes
#4
Jun Lu, Xuhong Hou, Hong Tu, Zhenghao Tang, Yongbing Xiang, Yuqian Bao, Jianren Gu, Weiping Jia
AIMS/INTRODUCTION: It has not been reported whether chronic hepatitis B virus (HBV) infection (CHB) is associated with a specific type of diabetes. We sought to investigate the prevalence of CHB status in different diabetes subtypes among Chinese population MATERIALS AND METHODS: This is a cross-sectional study. 381 cases with adult-onset autoimmune diabetes,1365 patients with type 2 diabetes, and 1365 non-diabetic controls were recruited from Jun 2005 to Feb 2014.The exclusion criteria included: (1) HCV-antibody positive, (2) hepatic cirrhosis, (3) malignant neoplasm and severe renal dysfunction (serum creatinine > 450 umol/L)...
December 8, 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/27928900/determining-the-health-related-quality-of-life-in-individuals-with-haemophilia-in-developing-economies-results-from-the-brazilian-population
#5
T Salomon, D G Chaves, S Brener, P R J Martins, J V M Mambrini, S V Peixoto
INTRODUCTION: Several studies show the negative impact of haemophilia in health-related quality of life (HRQOL). This issue is not well explored in developing countries. OBJECTIVES: This cross-sectional study aimed to evaluate the HRQOL and its associated factors in patients with haemophilia A/B in Brazil. Data were collected by questionnaire and in medical records, including a Portuguese version of Haem-A-Qol. RESULTS: Brazilian patients were invited to the study and 175 participants (147 haemophilics A and 28 haemophilics B) were included...
December 8, 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/27927266/enzymatically-modified-starch-up-regulates-expression-of-incretins-and-sodium-coupled-monocarboxylate-transporter-in-jejunum-of-growing-pigs
#6
B U Metzler-Zebeli, R Ertl, D Grüll, T Molnar, Q Zebeli
Dietary effects on the host are mediated via modulation of the intestinal mucosal responses. The present study investigated the effect of an enzymatically modified starch (EMS) product on the mucosal expression of genes related to starch digestion, sugar and short-chain fatty acid (SCFA) absorption and incretins in the jejunum and cecum in growing pigs. Moreover, the impact of the EMS on hepatic expression of genes related to glucose and lipid metabolism, and postprandial serum metabolites were assessed. Barrows (n=12/diet; initial BW 29 kg) were individually fed three times daily with free access to a diet containing either EMS or waxy corn starch as control (CON) for 10 days...
December 8, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27927202/positive-association-between-serum-apolipoprotein-m-levels-and-hepatitis-b-virus-dna-load-in-hbeag-negative-chronic-hepatitis-b
#7
Ting Shen, Wei Min Wu, Wen Han Du, Lin Wang, La Gu He, Li Tan, ZeYou Wang, Ruohong Chen, Min Hu, Ya Ping Ren
BACKGROUND: Hepatitis virus B (HBV) has infected millions of people worldwide. Notably, such infections can be associated with hepatic complications. Levels of apolipoprotein M (apoM), a component of high-density lipoprotein (HDL), are known to be significantly elevated in patients with chronic hepatitis B (CHB). The aim of this study was to investigate the relationship between HBV DNA load in serum and serum apoM levels in patients with CHB. METHODS: A total of 73 HBeAg-negative CHB patients, 50 HBeAg-positive CHB patients, and 79 non-CHB controls were included in the study cohort...
December 7, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27925503/persistence-of-protective-anti-hbs-antibody-levels-and-anamnestic-response-to-hbv-booster-vaccination-a-cross-sectional-study-among-healthcare-students-20%C3%A2-years-following-the-universal-immunization-campaign-in-italy
#8
Guglielmo Dini, Alessandra Toletone, Ilaria Barberis, Nicoletta Debarbieri, Emanuela Massa, Chiara Paganino, Francesca Bersi, Alfredo Montecucco, Cristiano Alicino, Paolo Durando
Vaccination against Hepatitis B Virus (HBV) became mandatory in Italy for all newborns and twelve years-old individuals in the 1991. The immunogenicity of HBV vaccine and the effectiveness of the universal immunization strategy have been widely demonstrated. However the need to assess the antibody concentrations above the well known serological correlate of protection for HBV infection (≥ 10 mIU/mL), established in individuals immunized with a three doses vaccination course, is still recommended in subjects exposed to occupational risks in different settings, particularly the healthcare services...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925349/hepatitis-c-viremia-reversibly-maintains-subset-of-antigen-specific-t-bet-tissue-like-memory-b-cells
#9
Li-Yuan Chang, Yonghai Li, David E Kaplan
BACKGROUND: Chronic antigen exposure and/or aging increases the frequency of T-box expressed in T cells (T-bet)-expressing B-lymphocytes in mice. The frequency and significance of B-cell T-bet expression during chronic hepatitis C (HCV) infection in human subjects has never been described. METHODS: Healthy controls, cirrhotic and non-cirrhotic HCV-infected patients, and non-HCV patients with cirrhosis were recruited. Peripheral blood mononuclear cells were phenotyped for expression of T-bet and related markers by flow cytometry...
December 7, 2016: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/27925300/the-importance-of-serum-biglycan-levels-as-a-fibrosis-marker-in-patients-with-chronic-hepatitis-b
#10
Rafiye Ciftciler, Seren Ozenirler, Aysegul Atak Yucel, Mustafa Cengiz, Gulbanu Erkan, Erkan Buyukdemirci, Cemile Sönmez, Guldal Yılmaz Esendaglı
BACKGROUND: Liver biopsy is recommended in the majority of patients with chronic viral hepatitis for fibrosis evaluation. Because of the potential risks of liver biopsy, many studies related to non-invasive biomarkers of hepatic fibrosis have been performed. We aimed to assess the diagnostic value of serum biglycan as a non-invasive fibrosis marker in chronic hepatitis B patients. METHODS: This study included 120 patients with biopsy-proven hepatitis B patients and 60 healthy controls...
December 7, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27923614/antiviral-therapy-inhibits-viral-reactivation-and-improves-survival-after-repeat-hepatectomy-for-hepatitis-b-virus-related-recurrent-hepatocellular-carcinoma
#11
Shengyu Huang, Yong Xia, Zhengqing Lei, Qifei Zou, Jun Li, Tian Yang, Kui Wang, Zhenlin Yan, Xuying Wan, Feng Shen
BACKGROUND: To explore the impact of antiviral therapy (AVT) on short- and long-term outcomes after re-hepatectomy for patients with recurrent HBV-related hepatocellular carcinoma (HCC). STUDY DESIGN: The data of 583 consecutive patients who underwent re-hepatectomy for intrahepatic recurrence of HBV-related HCC after initial hepatectomy between 2006 and 2011 at the Eastern Hepatobiliary Surgery Hospital were analyzed. Tumor re-recurrence, recurrence to death survival (RTDS) and overall survival (OS) were compared using the Kaplan-Meier method and log-rank test...
December 3, 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27922109/regulation-of-hepcidin-expression-by-inflammation-induced-activin-b
#12
Yohei Kanamori, Makoto Sugiyama, Osamu Hashimoto, Masaru Murakami, Tohru Matsui, Masayuki Funaba
Activin B is induced in response to inflammation in the liver and enhances hepcidin expression, but the source of activin B and the molecular mechanism underlying hepcidin induction are not clear yet. Lipopolysaccharide (LPS)-induced inflammation induced inhibin βB but not inhibin α or inhibin βA expression in the liver, implicating activin B induction. Immunoreactive inhibin βB was detected in endothelial cells and Kupffer cells in LPS-treated liver. Activin B, but not activin A or activin AB, directly increased hepcidin expression...
December 6, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27920479/ceruloplasmin-a-reliable-marker-of-fibrosis-in-chronic-hepatitis-b-virus-patients-with-normal-or-minimally-raised-alanine-aminotransferase
#13
Da-Wu Zeng, Jing Dong, Jia-Ji Jiang, Yue-Yong Zhu, Yu-Rui Liu
AIM: To develop a non-invasive model to evaluate significant fibrosis and cirrhosis by investigating the association between serum ceruloplasmin (CP) levels and liver fibrosis in chronic hepatitis B (CHB) patients with normal or minimally raised alanine aminotransferase (ALT). METHODS: Serum samples and liver biopsy were obtained from 193 CHB patients with minimally raised or normal ALT who were randomly divided into a training group (n = 97) and a validation group (n = 96)...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27920478/diabetes-mellitus-may-affect-the-long-term-survival-of-hepatitis-b-virus-related-hepatocellular-carcinoma-patients-after-liver-transplantation
#14
Qing Zhang, Yong-Lin Deng, Chang Liu, Li-Hong Huang, Lei Shang, Xin-Guo Chen, Le-Tian Wang, Jin-Zan Du, Ying Wang, Pei-Xiao Wang, Hui Zhang, Zhong-Yang Shen
AIM: To determine whether diabetes mellitus (DM) affects prognosis/recurrence after liver transplantation (LT) for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). METHODS: A retrospective study was conducted between January 2000 and August 2013 on 1631 patients with HBV-related HCC who underwent LT with antiviral prophylaxis. Patient data were obtained from the China Liver Transplant Registry (https://www.cltr.org/). To compare the outcomes and tumor recurrence in the HBV-related HCC patients with or without DM, statistical analyses were conducted using χ(2) tests, Mann-Whitney tests, the Kaplan-Meier method, log-rank tests and multivariate step-wise Cox regression analysis...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27920474/hepatitis-b-virus-upregulates-host-expression-of-%C3%AE-1-2-mannosidases-via-the-ppar%C3%AE-pathway
#15
Song Hu, Li-Bin Jiang, Xiao-Jing Zou, Wei Yi, De-Ying Tian
AIM: To assess the effects of hepatitis B virus (HBV) on the expression of host α-1,2-mannosidases and determine the underlying mechanisms. METHODS: We measured the expression levels of MAN1A1, MAN1A2, MAN1B1, and MAN1C1 in cell lines HepG2.2.15, HepN10, HepAD38 and HepG2 by Western blot. Viral antigens (HBsAg and HBeAg) in the culture medium were measured using the chemiluminescence method. HBV DNA quantification assays were performed using a commercial real-time PCR kit...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27919960/dancr-acts-as-a-diagnostic-biomarker-and-promotes-tumor-growth-and-metastasis-in-hepatocellular-carcinoma
#16
Xiang Ma, Xin Wang, Chao Yang, Zusen Wang, Bing Han, Liqun Wu, Likun Zhuang
BACKGROUND: Long non-coding RNA differentiation antagonizing non-protein coding RNA (DANCR) is considered to be an oncogene in many cancer types. However, the role of DANCR in diagnosis and progression of hepatocellular carcinoma (HCC) is still unknown. PATIENTS AND METHODS: In this study, 146 participants including healthy volunteers (HVs) and patients with chronic hepatitis B (CHB), cirrhosis and HCC were recruited. RESULTS: Firstly, quantitative reverse transcription-PCR analysis showed that DANCR was up-regulated in tumor tissues and plasma of patients with HCC, and its expression was highly correlated with microvascular and liver capsule invasion of HCC...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27917568/clinical-characteristics-and-outcomes-of-patients-with-recurrent-chronic-hepatitis-b-after-nucleos-t-ide-analog-withdrawal-with-stringent-cessation-criteria-a-prospective-cohort-study
#17
Zhirong Liu, Feng Liu, Lei Wang, Youde Liu, Meng Zhang, Tao Li
AIM: The aim of this study was to explore the clinical characteristics and outcomes of patients with recurrent chronic hepatitis B meeting the cessation criteria outlined by the 2008 Asian Pacific Association for the Study of the Liver guidelines. METHODS: In total, 223 chronic hepatitis B patients who met the cessation criteria and discontinued nucleos(t)ide analog therapy were prospectively included. They were monitored monthly during the first 4 months and every 3-6 months thereafter...
November 7, 2016: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/27917462/iron-overload-across-the-spectrum-of-non-transfusion-dependent-thalassaemias-role-of-erythropoiesis-splenectomy-and-transfusions
#18
John B Porter, Maria Domenica Cappellini, Antonis Kattamis, Vip Viprakasit, Khaled M Musallam, Zewen Zhu, Ali T Taher
Non-transfusion-dependent thalassaemias (NTDT) encompass a spectrum of anaemias rarely requiring blood transfusions. Increased iron absorption, driven by hepcidin suppression secondary to erythron expansion, initially causes intrahepatic iron overload. We examined iron metabolism biomarkers in 166 NTDT patients with β thalassaemia intermedia (n = 95), haemoglobin (Hb) E/β thalassaemia (n = 49) and Hb H syndromes (n = 22). Liver iron concentration (LIC), serum ferritin (SF), transferrin saturation (TfSat) and non-transferrin-bound iron (NTBI) were elevated and correlated across diagnostic subgroups...
December 5, 2016: British Journal of Haematology
https://www.readbyqxmd.com/read/27917266/telbivudine-vs-tenofovir-in-hepatitis-b-e-antigen-negative-chronic-hepatitis-b-patients-optima-roadmap-study
#19
Zahari Krastev, Diana Petrova, Iskren Kotzev, Mustafa Kemal Celen, Meryl Mendelson, Richa Chandra, Priti Pandey, Kamal Hamed
AIM: To make efficacy and safety comparison of telbivudine-raodmap and tenofovir-roadmap in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients. METHODS: This was the first prospective, randomised, two-arm, open-label, non-inferiority study in HBeAg-negative CHB patients that compared telbivudine and tenofovir administered as per roadmap concept. Patients were treated up to 24 wk and, depending on virologic response, continued the same therapy or received add-on therapy up to 104 wk...
November 18, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/27916988/circulating-scd36-levels-in-patients-with-non-alcoholic-fatty-liver-disease-and-controls
#20
S Heebøll, M K Poulsen, M J Ornstrup, T N Kjær, S B Pedersen, S Nielsen, H Grønbæk, A Handberg
BACKGROUND AND OBJECTIVE: CD36 is implicated in fatty acid uptake in multiple tissues, including hepatocytes and adipocytes. Circulating CD36 (sCD36) is increased in non-alcoholic fatty liver disease (NAFLD).We explored this association further by investigating correlations between sCD36 levels, intrahepatic lipid content and markers of obesity in NAFLD patients and controls. METHODS: 111 NAFLD patients and 33 normal/overweight controls were included. Intrahepatic lipid content was measured by MR spectroscopy; and subgroups of participants had a dual-energy X-ray absorptiometry (n=99), magnetic resonance imaging (n=94, subcutaneous and visceral adipose tissue) and liver biopsy (n=28 NAFLD patients) performed...
December 5, 2016: International Journal of Obesity: Journal of the International Association for the Study of Obesity
keyword
keyword
92287
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"