Ilie Onu, Robert Gherghel, Isabella Nacu, Florina-Daniela Cojocaru, Liliana Verestiuc, Daniela-Viorelia Matei, Dan Cascaval, Ionela Lacramioara Serban, Daniel Andrei Iordan, Alexandra Tucaliuc, Anca-Irina Galaction
Known as the degenerative disease of the knee with the highest prevalence, knee osteoarthritis (KOA) is characterized by a gradual destructive mechanism that, in severe cases, can provoke the need for total knee substitution. As the disease progresses, various enzymatic, immunological, and inflammatory processes abnormally degrade hyaluronic acid (HA), SF's main component, and affect the concentrations of specific proteins, with the final results seriously endangering synovial fluid (SF)'s rheological and tribological features and characteristics...
February 17, 2024: Biomedicines