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https://www.readbyqxmd.com/read/29656065/penile-prosthesis-in-solid-organ-transplant-recipients-a-matched-cohort-study
#1
Andrew Y Sun, Paurush Babbar, Bradley C Gill, Kenneth W Angermeier, Drogo K Montague
OBJECTIVES: To determine whether solid organ transplant (SOT) patients are at higher risk of developing complications after inflatable penile prosthesis (IPP) implantation. METHODS: We retrospectively reviewed outcomes data for all patients with SOT who underwent IPP placement at our institution. A cohort of age-matched IPP recipients without SOT were used as controls. RESULTS: We identified 26 patients who underwent SOT and IPP between 1999-2015, and 26 controls...
April 12, 2018: Urology
https://www.readbyqxmd.com/read/29652099/a-novel-dynamic-opto-thermo-mechanical-stress-testing-device-1-design-of-the-device
#2
T Z N Sokkar, K A El-Farahaty, M A El-Bakary, M I Raslan, F E Hanash
This article presents a dynamic opto-thermo-mechanical stress testing device to characterize fiber properties. The device has multi-modes and consists of many functions. These modes include stretching, bending, rotating, twisting, and heating processes. Every process can be controlled by micro-controller unit via software programs specially designed for this purpose. The micro-controller unit can execute two different processes at the same time. Such as, dynamic stretching process under the effect of thermal treatment, dynamic stretching process and relaxation, bending process under the effect of thermal treatment, and so forth...
April 13, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29642411/presence-of-human-enteric-viruses-protozoa-and-indicators-of-pathogens-in-the-bagmati-river-nepal
#3
Sarmila Tandukar, Jeevan B Sherchand, Dinesh Bhandari, Samendra P Sherchan, Bikash Malla, Rajani Ghaju Shrestha, Eiji Haramoto
Quantification of waterborne pathogens in water sources is essential for alerting the community about health hazards. This study determined the presence of human enteric viruses and protozoa in the Bagmati River, Nepal, and detected fecal indicator bacteria (total coliforms, Escherichia coli , and Enterococcus spp.), human-fecal markers (human Bacteroidales and JC and BK polyomaviruses), and index viruses (tobacco mosaic virus and pepper mild mottle virus). During a one-year period between October 2015 and September 2016, a total of 18 surface water samples were collected periodically from three sites along the river...
April 6, 2018: Pathogens
https://www.readbyqxmd.com/read/29628172/-impact-of-an-evaluation-of-the-professional-practices-on-the-relevance-of-proton-pump-inhibitors-prescriptions-pertinence-at-the-hospital
#4
A Daumas, E Garros, H Mendizabal, S Gayet, F Bernard, D Bagnères, A-L Demoux, P Rossi, P Villani, B Granel
INTRODUCTION: Proton pump inhibitors (PPI) are widely prescribed for unrecognized indications, at high a dose and for a long duration, in spite of side effects and numerous drug interactions. In 2009, the HAS (French Health Authority) published recommendations of good prescription but the latter are poorly respected. In this context of over prescription and additional cost for the society, we performed a professional practice evaluation of on the model of the Deming wheel. The objective of this work was to optimize the relevance of the prescriptions of the IPP in two services of internal medicine and geriatrics through an evaluation of the professional practices...
April 5, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29616478/official-control-of-plant-protection-products-in-poland-detection-of-illegal-products
#5
Marek Miszczyk, Marlena Płonka, Tomasz Stobiecki, Dorota Kronenbach-Dylong, Kazimierz Waleczek, Roland Weber
Market presence of illegal and counterfeit pesticides is now a global problem. According to data published in 2012 by the European Crop Protection Association (ECPA), illegal products represent over 10% of the global market of plant protection products. Financial benefits are the main reason for the prevalence of this practice. Counterfeit and illegal pesticides may contain substances that may pose a threat to the environment, crops, animals, and humans, inconsistent with the label and registration dossier...
April 3, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29603559/enzymatic-formation-of-a-skipped-methyl-substituted-octaprenyl-side-chain-of-longestin-ks-505a-involvement-of-homo-ipp-as-a-common-extender-unit
#6
Taro Ozaki, Sandip S Shinde, Lei Gao, Ryo Okuizumi, Chengwei Liu, Yasushi Ogasawara, Xiaoguang Lei, Tohru Dairi, Atsushi Minami, Hideaki Oikawa
Longestin (KS-505a), a specific inhibitor of phosphodiesterase, is a meroterpenoid that consists of a unique octacyclic terpene skeleton with branched methyl groups at unusual positions (C1 and C12). The biochemical analysis of Lon23, a methyltransferase involved in the biosynthesis of longestin, demonstrated that methylation of IPP afforded 3Z-3-methyl IPP. This compound as well as IPP was selectively accepted as extender units by Lon22, a geranylgeranyl diphosphate (GGPP) synthase homolog, to yield dimethylated GGPP (dmGGPP)...
March 30, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29602329/psychological-abuse-substance-abuse-distress-dissatisfaction-with-friendships-and-incident-psychiatric-problems
#7
Mashhood Ahmed Sheikh
OBJECTIVE: The aim of this study was to assess the mediating role of dissatisfaction with friendships in adulthood in the associations between psychological abuse in childhood, substance abuse distress in childhood, and incident psychiatric problems (IPPs) in adulthood over 13 years of follow-up. METHODS: We used data collected from 1994 to 2008 within the framework of the Tromsø Study (N = 9502), a representative, longitudinal, prospective cohort study. Poisson regression analysis was used to assess the associations between psychological abuse, substance abuse distress, dissatisfaction with friendships in adulthood, and IPPs in adulthood...
May 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29589622/orientation-direction-dependency-of-cavitation-in-pre-oriented-isotactic-polypropylene-at-large-strains
#8
Ying Lu, Glen Thompson, Dong Lyu, Philip Caton-Rose, Phil Coates, Yongfeng Men
Orientation direction dependency of whitening activated at large strains was studied using four pre-oriented isotactic polypropylene (iPP) samples with different molecular weights stretched along different directions with respect to the pre-orientation (0°, 45°, and 90°) by means of in situ wide-, small-, and ultra-small-angle X-ray scattering techniques. A macroscopic fracture of iPP materials was also observed following the stress whitening at large strains. These two associated processes in pre-oriented iPP samples at elevated temperatures were found to be governed by not only the molecular weight of iPP but also the pre-orientation direction...
March 28, 2018: Soft Matter
https://www.readbyqxmd.com/read/29562905/a-qualitative-exploration-of-the-client-experience-of-inter-professional-practice-in-the-delivery-of-activeplus-a-combined-smoking-cessation-and-physical-activity-intervention
#9
G A O'Sullivan, Clare Hanlon, T Dentry, T Morris, L Banting
BACKGROUND: Research investigating interprofessional practice (IPP) frameworks has predominately focused on the service delivery of IPP or educating practitioners through interprofessional education. Minimal research has addressed client outcomes or the experience of clients with IPP in real world contexts. In this paper, we explore the experience of seven participants in the ActivePlus program, an IPP-based smoking cessation intervention combined with physical activity promotion. METHODS: Participants informed on their program experiences through post-program in-depth interviews...
March 21, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29550745/quantum-chemical-study-on-gas-phase-pyrolysis-of-p-isopropenylphenol
#10
Anand Mohan Verma, Harshal D Kawale, Kushagra Agrawal, Nanda Kishore
In the pyrolysis of Sphagnum moss species, p-isopropenylphenol (p-IPP) is a major product which has been considered in this density functional theory based computational study for its conversion to various products such as benzene, phenol, 4-propenylphenol, indan-5-ol, 4-propylcyclohexanone, 4-cyclopropylphenol, etc. In order to achieve these products, eight different reaction schemes are performed using B3LYP/6-311 + g (d,p) level of theory. Further, thermodynamic properties such as reaction free energies and reaction enthalpies associated with these eight reaction schemes are developed in the temperature range of 298-898 K...
March 9, 2018: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/29530749/integrated-analysis-of-isopentenyl-pyrophosphate-ipp-toxicity-in-isoprenoid-producing-escherichia-coli
#11
Kevin W George, Mitchell Thompson, Joonhoon Kim, Edward E K Baidoo, George Wang, Veronica Teixeira Benites, Christopher J Petzold, Leanne Jade G Chan, Suzan Yilmaz, Petri Turhanen, Paul D Adams, Jay D Keasling, Taek Soon Lee
Isopentenyl pyrophosphate (IPP) toxicity presents a challenge in engineered microbial systems since its formation is unavoidable in terpene biosynthesis. In this work, we develop an experimental platform to study IPP toxicity in isoprenol-producing Escherichia coli. We first characterize the physiological response to IPP accumulation, demonstrating that elevated IPP levels are linked to growth inhibition, reduced cell viability, and plasmid instability. We show that IPP toxicity selects for pathway "breakage", using proteomics to identify a reduction in phosphomevalonate kinase (PMK) as a probable recovery mechanism...
March 9, 2018: Metabolic Engineering
https://www.readbyqxmd.com/read/29523479/andrianne-mini-jupette-graft-at-the-time-of-inflatable-penile-prosthesis-placement-for-the-management-of-post-prostatectomy-climacturia-and-minimal-urinary-incontinence
#12
Faysal A Yafi, Robert Andrianne, Laith Alzweri, Jeffrey Brady, Michael Butcher, Daniel Chevalier, Kenneth J DeLay, Antoine Faix, Georgios Hatzichristodoulou, Wayne J G Hellstrom, Lawrence Jenkins, Tobias S Kohler, Daniar Osmanov, Sun Hung Park, M David Schwabb, Robert Valenzuela, Koenraad van Renterghem, Steven K Wilson
BACKGROUND: After radical prostatectomy (RP), erectile dysfunction, often necessitating the need for inflatable penile prosthesis (IPP) insertion, and urinary incontinence and climacturia can ensue. AIM: To assess the efficacy and safety of the mini-jupette, a mesh used to approximate the medial aspects of the 2 corporotomies at the time of IPP insertion, for the management of climacturia and urine leakage in patients with minimal incontinence. METHODS: We conducted a pilot multicenter study of patients with post-RP erectile dysfunction and climacturia and/or mild urinary incontinence (≤2 pads/day [ppd]) undergoing IPP insertion with concomitant placement of a mini-jupette graft...
March 6, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29517679/observational-study-pelvic-ultrasound-a-useful-tool-in-the-diagnosis-and-differentiation-of-precocious-puberty-in-chinese-girls
#13
Xiaoduo Wen, Denggui Wen, Hui Zhang, Huifeng Zhang, Yi Yang
Rapid and noninvasive diagnosis on and differentiation between normal, central precocious puberty (CPP), and isolated precocious puberty (IPP) is imperative before a decision can be made with gonadotropin-releasing hormone (GnRH) agonist treatment. Our study aims to evaluate such a role by pelvic ultrasound.We consecutively enrolled 84 cases of IPP (59 with premature thelarche/ pubarche and 25 with premature menarche), 47 CPP, and 177 age-matched normal controls. The IPP and CPP were diagnosed by clinical examination and GnRH-stimulation test and confirmed by over 2 years' follow-up...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29501367/the-fat-mass-index-not-the-fat-free-mass-index-is-associated-with-impaired-physical-performance-in-older-adult-subjects-evidence-from-a-cross-sectional-study
#14
Maribel Ramírez Torres, Roxana E Ruiz Valenzuela, Julián Esparza-Romero, Miriam T López Teros, Heliodoro Alemán-Mateo
BACKGROUND: Impaired physical performance (IPP) and physical disability (PD) are two serious public health problems in older adult populations worldwide. While studies show that changes in body composition are important risk factors for developing these conditions, there is little evidence that the fat-free mass (FFM) and fat mass (FM) indices (FFMI and FMI, respectively) are associated with IPP in older men and women. This study assessed the association among FFMI, FMI, and IPP using Short Physical Performance Battery (SPPB) in Mexican men and women aged over 60 years...
February 17, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29495506/high-precision-ionosphere-monitoring-using-continuous-measurements-from-bds-geo-satellites
#15
Haiyan Yang, Xuhai Yang, Zhe Zhang, Kunjuan Zhao
The current constellation of the BeiDou Navigation Satellite System (BDS) consists of five geostationary earth orbit (GEO) satellites, five inclined geosynchronous satellite orbit (IGSO) satellites, and four medium earth orbit (MEO) satellites. The advantage of using GEO satellites to monitor the ionosphereis the almost motionless ionospheric pierce point (IPP), which is analyzed in comparison with the MEO and IGSO satellites. The results from the analysis of the observations using eight tracking sites indicate that the ionospheric total electron content (TEC) sequence derived from each GEO satellite at their respective fixed IPPs is always continuous...
February 27, 2018: Sensors
https://www.readbyqxmd.com/read/29492584/penoscrotal-versus-minimally-invasive-infrapubic-approach-for-inflatable-penile-prosthesis-placement-a-single-center-matched-pair-analysis
#16
Pietro Grande, Gabriele Antonini, Cristiano Cristini, Ettore De Berardinis, Antonio Gatto, Giovanni Di Lascio, Andrea Lemma, Giuseppe Gentile, Giovanni Battista Di Pierro
PURPOSE: To compare perioperative results, safety and efficacy profile in patients receiving inflatable penile prosthesis (IPP) via penoscrotal (PS) or minimally invasive infrapubic (MII) approach for erectile dysfunction. METHODS: A matched-pair analysis was performed including 42 patients undergoing IPP implantation via PS (n = 21) or MII (n = 21) between 2011 and 2016. Clinical and surgical data were prospectively collected. Patients' and partners' outcomes were assessed by the International Index of Erectile Function (IIEF), Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) and Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) questionnaires...
February 28, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29479218/parent-led-interventions-in-reducing-infant-vaccination-pain-after-participation-in-a-longitudinal-randomized-control-trial
#17
Caitlin McNair, Many Fung, Anna Taddio, Moshe Ipp, Steven Moss, Stephen Baker, Jonathan Tolkin, Malini Dave, Sharmeen Feerasta, Preeya Govan, Rebecca Pillai Riddell
No abstract text is available yet for this article.
July 2017: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29452979/3-piece-inflatable-penile-prosthesis-placement-following-radical-cystoprostatectomy-and-urinary-diversion-technique-and-outcomes
#18
Jeffrey Loh-Doyle, Mukul B Patil, Hari Sawkar, Kevin Wayne, Stuart D Boyd
BACKGROUND: After radical cystoprostatectomy (RC), postoperative erectile dysfunction (ED) is a common consequence with multiple contributing etiologies. The inflatable penile prosthesis (IPP) offers patients a definitive treatment option when ED is refractory to medical therapies. Because of the hostile postoperative anatomy of these patients, a careful surgical approach is necessary for successful outcomes and to avoid adjacent organ injury. To date, there is no series describing the outcomes of 3-piece IPP placement in patients with urinary diversions...
February 13, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29451871/environmental-heterogeneity-blurs-the-signature-of-dispersal-syndromes-on-spatial-patterns-of-woody-species-in-a-moist-tropical-forest
#19
Pablo Ramón, Eduardo Velázquez, Adrián Escudero, Marcelino de la Cruz
We assessed the relative importance of dispersal limitation, environmental heterogeneity and their joint effects as determinants of the spatial patterns of 229 species in the moist tropical forest of Barro Colorado Island (Panama). We differentiated five types of species according to their dispersal syndrome; autochorous, anemochorous, and zoochorous species with small, medium-size and large fruits. We characterized the spatial patterns of each species and we checked whether they were best fitted by Inhomogeneous Poisson (IPP), Homogeneous Poisson cluster (HPCP) and Inhomogeneous Poisson cluster processes (IPCP) by means of the Akaike Information Criterion...
2018: PloS One
https://www.readbyqxmd.com/read/29444892/role-of-protein-phosphatase-1-and-inhibitor-of-protein-phosphatase-1-in-nitric-oxide-dependent-inhibition-of-the-dna-damage-response-in-pancreatic-%C3%AE-cells
#20
Bryndon J Oleson, Aaron Naatz, Sarah C Proudfoot, Chay Teng Yeo, John A Corbett
Nitric oxide is produced at micromolar levels by pancreatic β-cells during exposure to proinflammatory cytokines. While classically viewed as damaging, nitric oxide also activates pathways that promote β-cell survival. We have shown that nitric oxide, in a cell type selective manner, inhibits the DNA damage response (DDR) and, in doing so, protects β-cells from DNA damage-induced apoptosis. This study explores potential mechanisms by which nitric oxide inhibits DDR signaling. We show that inhibition of DDR signaling (measured by γH2AX formation and the phosphorylation of KAP1) is selective for nitric oxide, as other forms of reactive oxygen/nitrogen species do not impair DDR signaling...
February 14, 2018: Diabetes
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