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Platelet rich plasma injection

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https://www.readbyqxmd.com/read/29667850/a-survey-of-fellowship-trained-upper-extremity-surgeons-on-treatment-of-lateral-epicondylitis
#1
Steven R Niedermeier, Nisha Crouser, Amy Speeckaert, Kanu S Goyal
BACKGROUND: The aim of the study is to investigate current management strategies for lateral epicondylitis by fellowship-trained upper extremity surgeons. METHODS: A 17-question survey of treatment approaches and outcomes related to lateral epicondylitis was sent to 3354 surgeons using the American Society for Surgery of the Hand and American Shoulder and Elbow Surgeons member databases. RESULTS: Six hundred twelve upper extremity surgeons completed the survey...
April 1, 2018: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29663626/treatment-of-auricular-keloids-by-triple-combination-therapy-surgical-excision-platelet-rich-plasma-and-cryosurgery
#2
Ehab Zaki Azzam, Salma Samir Omar
BACKGROUND: Surgical excision alone for auricular keloids is frequently followed by recurrence making combining treatment options necessary. OBJECTIVE: We aimed to assess the long-term efficacy of combining surgical excision, cryosurgery, and platelet-rich plasma (PRP) in treatment of auricular keloids. METHODS: This interventional study was carried out on fifty auricular keloids in 50 patients. Patients were subjected to a combination therapy of surgical excision of the keloids, intraoperative cryosurgery, and PRP injections...
April 16, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29657476/platelet-rich-plasma-injections-for-lateral-epicondylitis-of-the-elbow-reduce-the-need-for-surgical-intervention
#3
Graham Hastie, Mazen Soufi, James Wilson, Bibhas Roy
Objective: We aimed to assess the effectiveness of PRP injections in lateral epicondylitis of the elbow as it was felt after PRP introduction the numbers of patients requiring surgery for had reduced. Methods: We conducted a retrospective review of cases from the 1st January 2008 to 31st December 2015. The numbers of patients undergoing surgical release and the numbers of patients requiring PRP injections were recorded each year and the numbers of patients requiring surgery was compared pre and post PRP injection to ascertain if PRP introduction reduced surgical intervention...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29656808/injections-for-knee-osteoarthritis-corticosteroids-viscosupplementation-platelet-rich-plasma-and-autologous-stem-cells
#4
David M Levy, Kyle A Petersen, Margie Scalley Vaught, David R Christian, Brian J Cole
This article reviews the benefits of corticosteroid, viscosupplementation, platelet-rich plasma, and autologous mesenchymal stem cell injections for the treatment of patients with knee osteoarthritis. Integrating injections into both clinical and surgical practices is complicated given existing health insurance reimbursement policies. This review describes the outcomes associated with these interventions and appropriate methods of navigating the existing reimbursement pathways to help providers implement these treatments into their practices...
April 12, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29644468/-pharmacological-treatment-of-osteoarthritis-related-pain
#5
REVIEW
T A Nees, M Schiltenwolf
Joint pain due to osteoarthritis (OA) is often severe and disabling and affects a large proportion of the aging population impairing daily living and quality of life. Numerous pharmacological treatment approaches are available. Including major OA guidelines this review presents the current evidence of pharmacological therapies in OA-related pain and covers topical, oral and intraarticular treatment approaches. In patients with mild OA topical nonsteroidal antiinflammatory drugs (NSAIDs) can be recommended...
April 11, 2018: Der Schmerz
https://www.readbyqxmd.com/read/29626641/platelet-rich-plasma-versus-hyaluronic-acid-in-patients-with-hip-osteoarthritis-a-meta-analysis-of-randomized-controlled-trials
#6
REVIEW
Ye Ye, Xiang Zhou, Shuiwei Mao, Jun Zhang, Bingmin Lin
BACKGROUND: This study aims to compare the efficacy of intra-articular injection of hyaluronic acid (HA) and platelet-rich plasma (PRP) for treating hip osteoarthritis (OA). METHODS: We performed systematic searches in PubMed, EmBase, ScienceDirect Web of science and the Cochrane Library for relevant literature published in or before February 2018. Only randomized controlled trials (RCTs) were included. The risk of bias assessment was performed using the tool recommended in the Cochrane Handbook for Systematic Reviews of Interventions (version 5...
April 4, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29608156/effects-of-allogeneic-platelet-rich-plasma-prp-on-the-healing-process-of-sectioned-achilles-tendons-of-rats-a-methodological-description
#7
Laura Greimers, Pierre V Drion, Alain Colige, Vincent Libertiaux, Vincent Denoël, Christelle Lecut, André Gothot, Jean-François Kaux
This article describes the experimental procedures used to observe if PRP can positively affect tendon healing. There are 4 main steps to follow: induce a lesion in the Achilles tendon; prepare PRP and inject it (or the saline solution); remove the tendon; and perform biomechanical, molecular, and histological evaluations. At each step, all the procedures and methods are described in detail, so they can be reproduced easily. Achilles tendons have been surgically sectioned (removal of a 5-mm long section). Afterwards, PRP or saline solution was injected to study whether PRP has a positive effect on the healing of the tendon...
March 19, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29605861/synergistic-activity-of-platelet-rich-plasma-and-high-volume-image-guided-injection-for-patellar-tendinopathy
#8
Michele Abate, Luigi Di Carlo, Sandra Verna, Patrizia Di Gregorio, Cosima Schiavone, Vincenzo Salini
PURPOSE: Platelet rich plasma and high volume image guided injections of saline have been used in the treatment of patellar tendinopathy with positive results. As the different mechanisms of action do not interfere each other, it can be hypothesized that they can be used in combination. Aim of this study was twofold: first, to evaluate the efficacy of these two treatments in the management of patellar tendinopathy; second, to verify whether the combination of these therapies could provide further advantages...
March 31, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29604139/preliminary-observations-of-a-new-approach-to-tissue-repair-periphearal-blood-mononuclear-cells-in-platelet-rich-plasma-injected-into-skin-graft-area
#9
Catuscia Orlandi, Elena Bondioli, Michela Venturi, Davide Melandri
Our purpose was accelerating the physiologic wound healing, stimulating tissue regeneration and the reparative tissue processes in resistant skin ulcers as in a case of an erosive lichen planus of the soles and after a surgical treatment as for severe Darier disease. The challenge was to establish an effective therapy to enhance tissue healing by the injection of a mixture of peripheral blood mononuclear cells (PB-MNCs) and platelet-rich plasma (PRP) into a skin autograft area. This new perioperative biotechnological approach enriches PRP with the effects of PB-MNCs...
March 31, 2018: Experimental Dermatology
https://www.readbyqxmd.com/read/29601383/is-platelet-rich-plasma-injection-effective-for-chronic-achilles-tendinopathy-a-meta-analysis
#10
Yi-Jun Zhang, San-Zhong Xu, Peng-Cheng Gu, Jing-Yu Du, You-Zhi Cai, Chi Zhang, Xiang-Jin Lin
BACKGROUND: Chronic Achilles tendinopathy is common in the general population, and platelet-rich plasma (PRP) is seeing increased use to treat this problem. However, studies disagree as to whether PRP confers a beneficial effect for chronic Achilles tendinopathy, and no one to our knowledge has pooled the available randomized trials in a formal meta-analysis to try to reconcile those differences. QUESTIONS/PURPOSES: In the setting of a systematic review and meta-analysis of randomized controlled trials (RCTs), we asked: Does PRP plus eccentric strength training result in (1) greater improvements in Victorian Institute of Sports Assessment-Achilles (VISA-A) scores; (2) differences in tendon thickness; or (3) differences in color Doppler activity compared with placebo (saline) injections plus eccentric strength training in patients with chronic Achilles tendinopathy? METHODS: A search of peer-reviewed articles was conducted to identify all RCTs using PRP injection with eccentric training for chronic Achilles tendinopathy in the electronic databases of PubMed, Web of Science (SCI-E/SSCI/A&HCI), and EMBASE from January 1981 to August 2017...
March 28, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29601207/nonsurgical-treatments-of-patellar-tendinopathy-multiple-injections-of-platelet-rich-plasma-are-a-suitable-option-a-systematic-review-and-meta-analysis
#11
Luca Andriolo, Sante Alessandro Altamura, Davide Reale, Christian Candrian, Stefano Zaffagnini, Giuseppe Filardo
BACKGROUND: Patellar tendinopathy is a condition characterized by anterior knee activity-related pain. It has a high incidence among athletes engaged in jumping sports and may become a chronic condition. Nonoperative management is the first choice in these patients, and several nonsurgical treatment options have been proposed. Nonetheless, clear indications on the most effective approach to address patellar tendinopathy are still lacking. PURPOSE: To analyze the evidence on nonoperative options to treat chronic patellar tendinopathy through a systematic review of the literature and to perform a meta-analysis to identify the most effective nonsurgical option...
March 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29600719/comparison-of-plantar-fasciitis-injected-with-platelet-rich-plasma-vs-corticosteroids
#12
Sumit Kumar Jain, Kumar Suprashant, Sanjeev Kumar, Arun Yadav, Stephen R Kearns
BACKGROUND: Plantar fasciitis is one of the most common causes of heel pain. This prospective study compared the efficacy of local injection of corticosteroids vs platelet-rich plasma (PRP) in the treatment of plantar fasciitis. METHODS: Patients were randomly allocated into 2 groups of 40 each (group A and group B). Patients were treated with local corticosteroid injection in group A and autologous PRP injection in group B. Clinical assessment was done prior to the injection and at 1 month, 3 months, and 6 months following the injection, which included visual analog pain scale, subjective rating using the modified Roles and Maudsley score, functional outcome score by the Foot and Ankle Outcome Instrument (FAI) core scale, and the American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot scale...
March 1, 2018: Foot & Ankle International
https://www.readbyqxmd.com/read/29581613/intra-articular-platelet-rich-plasma-prp-injections-for-treating-knee-pain-associated-with-osteoarthritis-of-the-knee-in-the-japanese-population-a-phase-i-and-iia-clinical-trial
#13
Yu Taniguchi, Tomokazu Yoshioka, Akihiro Kanamori, Katsuya Aoto, Hisashi Sugaya, Masashi Yamazaki
Intra-articular platelet-rich plasma (PRP) injection has been found to be effective for treating osteoarthritis in patients from Western countries; however, the safety and efficacy of PRP have not been sufficiently investigated in Japanese patients. The present study aimed to evaluate the safety and feasibility of intra-articular PRP injection in Japanese patients with knee osteoarthritis. PRP without white blood cells was prepared using a single-spin centrifuge (PRGF-Endoret; BTI Biotechnology Institute, Vitoria, Spain)...
February 2018: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29561260/the-effect-of-corticosteroid-versus-platelet-rich-plasma-injection-therapies-for-the-management-of-lateral-epicondylitis-a-systematic-review
#14
Walid Ben-Nafa, Wendy Munro
INTRODUCTION: Lateral epicondylitis is a common musculoskeletal disorder of the upper limb. Corticosteroid injection has been widely used as a major mode of treatment. However, better understanding of the pathophysiology of the disease led to a major change in treating the disease, with new options including platelet-rich plasma (PRP) are currently used. Objectives/research aim: To systematically evaluate the effect of corticosteroid versus PRP injections for the treatment of LE. HYPOTHESIS: PRP injections provide longer-term therapeutic effect and less rate of complications compared to corticosteroid injection...
2018: SICOT-J
https://www.readbyqxmd.com/read/29554209/introducing-platelet-rich-stroma-platelet-rich-plasma-prp-and-stromal-vascular-fraction-svf-combined-for-the-treatment-of-androgenetic-alopecia
#15
Hieronymus P Stevens, Simone Donners, Julia de Bruijn
Background: Androgenetic alopecia (AGA) is characterized by miniaturization of the hair follicles gradually causing conversion of terminal hairs into vellus hairs, leading to progressive reduction of the density of hair on the scalp. Approved therapeutic options are limited and show side effects. Objectives: To evaluate injections of stromal vascular fraction (SVF), which is rich in adipose-derived stromal cells (ASCs) in combination with platelet-rich plasma (PRP) in the upper scalp as a new autologous treatment option for AGA...
March 15, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29554150/effect-of-leukocyte-reduced-platelet-rich-plasma-on-osteoarthritis-caused-by-cranial-cruciate-ligament-rupture-a-canine-gait-analysis-model
#16
José M Vilar, Maria E Manera, Angelo Santana, Giuseppe Spinella, Oliver Rodriguez, Mónica Rubio, José M Carrillo, Joaquín Sopena, Miguel Batista
The goal of this study was to objectively assess the effect of a platelet-rich plasma (PRP) derivate in English bulldogs with stifle degenerative joint disease secondary to cranial cruciate ligament rupture (CCLR). We used a force platform and affixed electrogoniometers to measure peak vertical force (PVF), vertical impulse (VI), stance time (ST), and angular range of motion (AROM), from 12 lame client-owned English bulldogs with post-CCLR stifle joint abnormalities. The 12 affected subjects were treated with 4 intra-articular injections of PRP, at 30-day intervals...
2018: PloS One
https://www.readbyqxmd.com/read/29551888/intra-articular-platelet-rich-plasma-versus-hyaluronic-acid-in-the-treatment-of-knee-osteoarthritis-a-meta-analysis
#17
Hua-Feng Zhang, Chen-Guang Wang, Hui Li, Yu-Ting Huang, Zhi-Jun Li
Purpose: Platelet-rich plasma (PRP) and hyaluronic acid (HA) have been increasingly used in recent years to treat knee osteoarthritis (OA). However, whether PRP is superior to HA is controversial. Methods: We conducted an electronic search of PubMed, Embase, ScienceDirect, and Cochrane library. The pooled data were analyzed using RevMan 5.1. Results: Three prospective and ten randomized trials were identified. PRP injections reduced pain more effectively than HA injections in OA of the knee at 6 months (mean difference [MD]=-14...
2018: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29546474/effects-of-subtenon-injected-autologous-platelet-rich-plasma-on-visual-functions-in-eyes-with-retinitis-pigmentosa-preliminary-clinical-results
#18
Umut Arslan, Emin Özmert, Sibel Demirel, Firdevs Örnek, Figen Şermet
PURPOSE: One of the main reasons for apoptosis and dormant cell phases in degenerative retinal diseases such as retinitis pigmentosa (RP) is growth factor withdrawal in the cellular microenvironment. Growth factors and neurotrophins can significantly slow down retinal degeneration and cell death in animal models. One possible source of autologous growth factors is platelet-rich plasma. The purpose of this study was to determine if subtenon injections of autologous platelet-rich plasma (aPRP) can have beneficial effects on visual function in RP patients by reactivating dormant photoreceptors...
March 15, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29529674/stem-cells-combined-with-platelet-rich-plasma-effectively-treat-corticosteroid-induced-osteonecrosis-of-the-hip-a-prospective-study
#19
Matthew T Houdek, Cody C Wyles, Mark S Collins, Benjamin M Howe, Andre Terzic, Atta Behfar, Rafael J Sierra
BACKGROUND: Randomized trials have shown the benefits of injecting bone marrow-derived mesenchymal stem cells (BmMSCs) after standard hip decompression in patients with osteonecrosis of the femoral head. However, the combination of BmMSCs and platelet-rich plasma (PRP) injected into the femoral head after decompression has not been reported previously. This study reports the results in a preliminary series of patients with osteonecrosis of the femoral head treated with BmMSCs plus PRP...
February 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29525907/autologous-platelet-rich-plasma-and-triamcinolone-acetonide-intralesional-injection-in-the-treatment-of-oral-erosions-of-pemphigus-vulgaris-a-pilot-study
#20
Mohamed Hussein Medhat El-Komy, Noha Adly Saleh, Marwah Adly Saleh
Oral erosions of pemphigus vulgaris (PV) represent a therapeutic challenge. In this work we compared intralesional injection of steroids (ILS) and autologous platelet-rich plasma (PRP) treatment of oral erosions of PV. In this split-mouth randomized double blind study, one side of the buccal mucosa of 11 PV patients was injected with 10 mg/ml triamcinolone and the opposite side was injected with 1 millilitre of autologous PRP every 14 days for 3 months. The percentage of clinical improvement, pemphigus disease area index and pain score were recorded before and after therapy...
March 10, 2018: Archives of Dermatological Research
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