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Pelvic organ prolapse, urinary incontinence

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https://www.readbyqxmd.com/read/27902825/association-between-the-amount-of-vaginal-mesh-used-with-mesh-erosions-and-repeated-surgery-after-repairing-pelvic-organ-prolapse-and-stress-urinary-incontinence
#1
Bilal Chughtai, Matthew D Barber, Jialin Mao, James C Forde, Sharon-Lise T Normand, Art Sedrakyan
Importance: Mesh, a synthetic graft, has been used in pelvic organ prolapse (POP) repair and stress urinary incontinence (SUI) to augment and strengthen weakened tissue. Polypropylene mesh has come under scrutiny by the US Food and Drug Administration. Objective: To examine the rates of mesh complications and invasive reintervention after the placement of vaginal mesh for POP repair or SUI surgery. Design, Setting, and Participants: This investigation was an observational cohort study at inpatient and ambulatory surgery settings in New York State...
November 30, 2016: JAMA Surgery
https://www.readbyqxmd.com/read/27872979/evaluation-of-isolated-urinary-stress-incontinence-according-to-the-type-of-levator-ani-muscle-lesion-using-3-4d-transperineal-ultrasound-36%C3%A2-months-post-partum
#2
José Antonio García Mejido, Pamela Valdivieso Mejias, Ana Fernández Palacín, María José Bonomi Barby, Paloma De la Fuente Vaquero, José Antonio Sainz Bueno
INTRODUCTION: Vaginal delivery can lead to pelvic floor disorders. Many authors have described pelvic floor injuries that can predict future defects such as urinary incontinence and pelvic organ prolapse. We propose the assessment of urinary stress incontinence and its association with levator ani muscle (LAM) microtrauma (>20% in the levator hiatus area during Valsalva) and macrotraumas (avulsion) identified by 3/4D transperineal ultrasound (3D-TpUS) 36 months post-partum. MATERIALS AND METHODS: This was a prospective observational study including 168 nulliparous women...
November 21, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27866958/use-of-concomitant-stress-incontinence-surgery-at-time-of-pelvic-organ-prolapse-surgery-since-release-of-the-2011-fda-health-notification-on-serious-complications-associated-with-transvaginal-mesh
#3
Alice Drain, Aqsa Khan, Erin L Ohmann, Benjamin M Brucker, Scott Smilen, Nirit Rosenblum, Victor W Nitti
PURPOSE: There is controversy regarding performing concomitant anti-incontinence procedures at the time of pelvic organ prolapse (POP) repair. Data supports improvement in stress urinary incontinence (SUI) with concomitant sling, but increased adverse events. We assessed trends in preoperative SUI evaluation, concomitant anti-incontinence procedure at POP surgery, and post-operative anti-incontinence procedures at our institution before and after the 2011 FDA Public Health Notification pertaining to vaginal mesh...
November 17, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27855713/microrna-29-facilitates-transplantation-of-bone-marrow-derived-mesenchymal-stem-cells-to-alleviate-pelvic-floor-dysfunction-by-repressing-elastin
#4
Minfei Jin, Yuelin Wu, Jun Wang, Weiping Ye, Lei Wang, Peipei Yin, Wei Liu, Chenhao Pan, Xiaolin Hua
BACKGROUND: Pelvic floor dysfunction (PFD) is a condition affecting many women worldwide, with symptoms including stress urinary incontinence (SUI) and pelvic organ prolapse (POP). We have previously demonstrated stable elastin-expressing bone marrow-derived mesenchymal stem cells (BMSCs) attenuated PFD in rats, and aim to further study the effect of microRNA-29a-3p regulation on elastin expression and efficacy of BMSC transplantation therapy. METHODS: We inhibited endogenous microRNA-29a-3p in BMSCs and investigated its effect on elastin expression by RT-PCR and Western blot...
November 17, 2016: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/27826638/urethral-pressure-reflectometry-in-women-with-pelvic-organ-prolapse-a-study-of-reproducibility
#5
Yasmine Khayyami, Gunnar Lose, Niels Klarskov
INTRODUCTION AND HYPOTHESIS: The mechanism of continence in women with pelvic organ prolapse (POP) before and after surgery remains unknown. Urethral pressure reflectometry (UPR) separates women with stress urinary incontinence (SUI) from continent women by measuring urethral opening pressure at an abdominal pressure of 50 cmH2O (P O-Abd 50). UPR can help identify women with POP at risk of postoperative de novo SUI. The aim of this study was to investigate the reproducibility of UPR in women with POP...
November 8, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27822887/coital-incontinence-a-factor-for-deteriorated-health-related-quality-of-life-and-sexual-function-in-women-with-urodynamic-stress-urinary-incontinence
#6
Magdalena Emilia Grzybowska, Dariusz Grzegorz Wydra
INTRODUCTION AND HYPOTHESIS: To assess the impact of coital incontinence (CI) on health-related quality of life (HRQoL) and quality of sexual function (QSF) in women with urodynamic stress urinary incontinence (SUI). METHODS: Women were recruited for this cross-sectional study from among 289 patients with lower urinary tract symptoms, underwent clinical and urodynamic evaluation. Of these 289 women, 127 sexually active women with SUI completed the King's Health Questionnaire (KHQ) and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ), of whom 97 were enrolled for the study...
November 7, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27797099/the-effect-of-perineal-lacerations-on-pelvic-floor-function-and-anatomy-at-6-months-postpartum-in-a-prospective-cohort-of-nulliparous-women
#7
Lawrence Leeman, Rebecca Rogers, Noelle Borders, Dusty Teaf, Clifford Qualls
OBJECTIVE: To determine the effect of perineal lacerations on pelvic floor outcomes, including urinary and anal incontinence, sexual function, and perineal pain in a nulliparous cohort with low incidence of episiotomy. METHODS: Nulliparous women were prospectively recruited from a midwifery practice. Pelvic floor symptoms were assessed with validated questionnaires, physical examination, and objective measures in pregnancy and 6 months postpartum. Two trauma groups were compared, those with an intact perineum or only 1st degree lacerations and those with second-, third-, or fourth-degree lacerations...
December 2016: Birth
https://www.readbyqxmd.com/read/27796427/is-hysterectomy-or-prior-reconstructive-surgery-associated-with-unsuccessful-initial-trial-of-pessary-fitting-in-women-with-symptomatic-pelvic-organ-prolapse
#8
Zoltan Nemeth, Nelli Farkas, Balint Farkas
INTRODUCTION AND HYPOTHESIS: There is little data in the literature regarding the feasibility and limitations of pessary therapy after pelvic reconstructive surgery for symptom recurrence for treating urinary incontinence. Hysterectomy is an important risk factor for failure of pessary fitting. We aimed to evaluate the influence of these prior surgeries on subsequent initial trials of fitting a pessary. METHODS: Six hundred and twenty-nine women with symptomatic pelvic organ prolapse (POP) were included in a prospective cohort study from January 2014 to December 2015...
October 28, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27796426/primary-care-providers-attitudes-knowledge-and-practice-patterns-regarding-pelvic-floor-disorders
#9
Donna Mazloomdoost, Lauren B Westermann, Catrina C Crisp, Susan H Oakley, Steven D Kleeman, Rachel N Pauls
INTRODUCTION AND HYPOTHESIS: Understanding barriers to seeking care for pelvic floor disorders is necessary. We sought to assess familiarity with pelvic floor disorders, as well as identify screening and referral patterns among primary care providers. METHODS: This Institutional Review Board approved study was distributed through a secure online server (SurveyMonkey®). Primary care providers within a large healthcare system were invited to participate in a 14-question survey regarding the prevalence, diagnosis, and treatment of urinary incontinence (UI), overactive bladder (OAB) syndrome, and pelvic organ prolapse (POP)...
October 28, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27780347/indications-and-complications-associated-with-the-removal-of-506-pieces-of-vaginal-mesh-used-in-pelvic-floor-reconstruction-a-multicenter-study
#10
John R Miklos, Orawee Chinthakanan, Robert D Moore, Deborah R Karp, Gladys M Nogueiras, G Willy Davila
STUDY OBJECTIVE: Synthetic mesh utilized to treat stress urinary incontinence (SUI) and pelvic organ prolapse (POP) can often result in postoperative complications. The objectives of this study were to determine: 1) the most common indications for mesh removal; 2) the incidences of the removal of specific mesh procedures (such as suburethral sling [SUS], transvaginal mesh [TVM], or sacrocolpopexy); and 3) the idences and types of surgical complications associated with mesh removal. DESIGN: This was a retrospective study...
October 26, 2016: Surgical Technology International
https://www.readbyqxmd.com/read/27779168/porcine-small-intestinal-submucosa-mesh-for-treatment-of-pelvic-organ-prolapsed
#11
Ting-Ting Cao, Xiu-Li Sun, Shi-Yan Wang, Xin Yang, Jian-Liu Wang
BACKGROUND: Pelvic organ prolapse (POP) is a major health concern that affects women. Surgeons have increasingly used prosthetic meshes to correct POP. However, the most common used is synthetic mesh, and absorbable mesh is less reported. This research aimed to evaluate the clinical effectiveness of porcine small intestinal submucosa (SIS). METHODS: Consecutive forty POP patients who met the inclusion criteria underwent pelvic reconstruction surgery with SIS between March 2012 and December 2013...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27776848/-clinical-practice-guidelines-synthesis-of-the-guidelines-for-the-surgical-treatment-of-primary-pelvic-organ-prolapse-in-women-by-the-afu-cngof-sifud-pp-snfcp-and-scgp
#12
L Le Normand, M Cosson, F Cour, X Deffieux, L Donon, P Ferry, B Fatton, J-F Hermieu, H Marret, G Meurette, A Cortesse, L Wagner, X Fritel
OBJECTIVE: Develop guidelines for surgery for primary pelvic organ prolapse (POP). METHODS: Literature review, establishment of levels of evidence, external review, and grading of recommendations by 5 French academic societies: Association Française d'Urologie, Collège National des Gynécologues et Obstétriciens Français, Société Interdisciplinaire d'Urodynamique et de Pelvi-Périnéologie, Société Nationale Française de Colo-proctologie, and Société de Chirurgie Gynécologique et Pelvienne...
October 21, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/27771853/failure-of-expectations-in-vaginal-surgery-lack-of-appropriate-consent-goals-and-expectations-of-surgery
#13
REVIEW
Debjyoti Karmakar, Peter L Dwyer
INTRODUCTION AND BACKGROUND: Vaginal surgery for the treatment of urinary stress incontinence (USI) and pelvic organ prolapse (POP) using a synthetic polypropylene mesh is going through a time of unprecedented turmoil and debate. This review focuses on vaginal surgery for vaginal prolapse and looks at the current scientific literature on issues surrounding surgery including consent and expectations. SAFETY AND EFFECTIVENESS OF SURGICAL OPTIONS: Synthetic mesh has been used both abdominally and vaginally to improve the effectiveness of POP surgery...
December 2016: Current Urology Reports
https://www.readbyqxmd.com/read/27763801/the-prevalence-of-symptomatic-pelvic-floor-disorders-in-women-in-bangladesh
#14
R M Islam, R J Bell, B Billah, M B Hossain, S R Davis
OBJECTIVE: To investigate the prevalence of, and risk factors for, pelvic floor disorders (PFDs) in women in Bangladesh. METHODS: A nationally representative sample of 1590 Bangladeshi women, aged 30-59 years, was recruited using a multistage cluster sampling technique, between September 2013 and March 2014. Urinary incontinence (UI), fecal incontinence (FI) and pelvic organ prolapse (POP) were assessed using validated questionnaires. The weighted prevalence and the factors associated with each PFD were investigated using multivariable weighted logistic regression...
October 20, 2016: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/27762472/treatment-of-total-pelvic-organ-prolapse-using-a-whole-biological-patch-a-pilot-study-of-17-patients
#15
Xianghua Liang, Lili Zhang, Yanwei Lv
AIM: A complete and non-splice porcine small-intestine submucosa (SIS) patch was used for total pelvic anatomical repair of organ prolapse. METHODS: This study included a total of 17 patients with severe total pelvic organ prolapse, including five patients with combined stress urinary incontinence (SUI). Panhysterectomy was performed, and then a porcine SIS patch was placed on the anterior (posterior) vaginal wall. The top of the vaginal wall was moved to the corresponding side of the vaginal wall, and the patch was sutured to bilateral uterosacral ligaments, the sacrospinous ligament, and arcus tendineus fasciae pelvis...
October 20, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27752911/prevalence-and-risk-factors-of-urinary-incontinence-among-perimenopausal-women-in-wuhan
#16
Shi Lu, Hong-Ling Zhang, Ya-Jun Zhang, Qing-Chun Shao
This study investigated the prevalence and risk factors of urinary incontinence (UI) among perimenopausal women in Wuhan. A cross-sectional survey was performed on 1067 women aged 40-65 years sampled in Wuhan urban area from April to October 2014. Information about demographic characteristics, menstruation, parity and UI symptoms was collected using a questionnaire. The data were evaluated by Chi-square test and multiple Logistic regression analysis. The prevalence rate of UI was 37.2%, with stress UI (32.2%) being more prevalent than urgency UI (21...
October 2016: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/27752749/variability-in-practice-patterns-in-stress-urinary-incontinence-and-pelvic-organ-prolapse-results-of-an-iuga-survey
#17
Dorothy Kammerer-Doak, Kamil Svabik, Tony Bazi
INTRODUCTION AND HYPOTHESIS: Members of the International Urogynecological Association (IUGA) come from different geographic locations and practice settings. A member survey regarding practice patterns provides valuable information for practitioners and researchers alike, and allows the IUGA to discover areas to focus on education and information dissemination. METHODS: A questionnaire was developed by the IUGA Research and Development committee and distributed electronically to IUGA surgeons...
October 17, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27738734/patient-satisfaction-and-regret-with-decision-differ-between-outcomes-in-the-composite-definition-of-success-after-reconstructive-surgery
#18
Waseem Khoder, Emily Hom, Anna Guanzon, Sarah Rose, Douglass Hale, Michael Heit
INTRODUCTION AND HYPOTHESIS: To evaluate patient satisfaction and regret with their decision for reconstructive surgery, and determine if they valued each item equally in the composite definition of success after making the decision for surgery. METHODS: A list was created including all patients who underwent laparoscopic sacral colpopexy or laparoscopic uterosacrocolpopexy. Patients were placed in mutually exclusive outcome categories (retreatment, symptomatic failure, anatomic failure, and surgical success)...
October 13, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27706005/stress-urinary-incontinence-in-women-with-multiple-sclerosis
#19
Caroline Massot, Hichem Khenioui, Olivier Agnani, Marc-Alexandre Guyot, Patrick Hautecoeur, Cécile Donze
PURPOSE: To report the prevalence and risk factors of stress urinary incontinence (SUI) and the prevalence of intrinsic sphincter deficiency in women with multiple sclerosis (MS). METHODS: We conducted a retrospective study. Female patients with MS, followed for lower urinary tract symptoms (LUTS) during a 15-year period were included. Demographic data, MS history, expanded disability status scale (EDSS) score at the urodynamic visit, obstetrical past, birth weight, LUTS, and urodynamic findings were collected...
September 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27704153/in-the-footsteps-of-bonney-and-nichols-hysterectomy-during-surgical-repair-of-pelvic-organ-prolapse
#20
Maurizio Serati, Diaa Rizk, Stefano Savatore
Based on the available urogynecological literature, the role of hysterectomy in the surgical strategy of pelvic organ prolapse (POP) repair remains controversial. Currently, there are no data to favor either the removal or preservation of the uterus in women with POP. The findings that hysterectomy may contribute to a higher success rate and to the development of urinary incontinence and/or female sexual dysfunction are not supported by evidence. It is not clear why both hysteropexy was sometimes performed in the presence of overt uterine prolapse and/or concomitant vaginal hysterectomy was often included in vaginal prolapse repair in the absence of uterine prolapse...
October 4, 2016: International Urogynecology Journal
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