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Abel Cordoba, Alexandre Escande, Pauline Comte, Ingrid Fumagalli, Lucie Bresson, Ndaye Mubiayi, Eric Lartigau
In November 2013, a woman with Herlyn-Werner-Wunderlich (HWW) syndrome was diagnosed with a locally advanced left cervical adenocarcinoma. The patient's malformation consisted of two uteri with two cervixes, a obstructed vagina, and a left renal agenesis. Classification FIGO: stage IIIa because of infiltration of the inferior third of the vagina wall. Locoregional management comprised an infrarenal lateral aortic lymphadenectomy followed by concomitant radio-chemotherapy to the pelvic (inguinal, pelvic, and infrarenal para aortic nodes) volumes...
February 2017: Journal of Contemporary Brachytherapy
H Zhang, H Qu, G Ning, B Cheng, F Jia, X Li, X Chen
AIM: To outline the anatomical variations of obstructive reproductive tract anomalies (ORTA) using magnetic resonance imaging (MRI) and its role in preoperative evaluation. MATERIALS AND METHODS: MRI and treatment of 21 paediatric patients with ORTA were reviewed and analysed. MRI findings were correlated with ultrasound and surgical findings. RESULTS: Patients presented in two distinct ways: primary amenorrhoea with cyclic pelvic pain, or progressive dysmenorrhoea...
March 7, 2017: Clinical Radiology
Jun-Li Tsai, Shang-Feng Tsai
INTRODUCTION: Urinary tract infection is a common disease in the general population. However, in patients with frequent urinary tract infection, it is important to determine any treatable cause to avoid recurrence. CASE PRESENTATION: Herlyn-Werner-Wunderlich syndrome or OHVIRA syndrome is a very rare congenital anomaly with uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. The earliest presentation of this syndrome is hematocolpos that develops during menstruation and results in dysmenorrhea and a pelvic mass shortly after menarche...
November 2016: Iranian Red Crescent Medical Journal
Maria Inês Reis, Ana Patrícia Vicente, Joana Cominho, Andrea Sousa Gomes, Luísa Martins, Filomena Nunes
We describe a Herlyn-Werner-Wunderlich syndrome (HWWS) patient with previous history of infertility who got pregnant without treatment and presented a pyometra in the contralateral uterus throughout the gestational period, despite multiple antibiotic treatments. Due to the uterus' congenital anomaly and the possibility of ascending infection with subsequent abortion, this pregnancy was classified as high-risk. We believe that the partial horizontal septum in the vagina may have contributed to the closure of the gravid uterus cervix, thus ensuring that the pregnancy came to term, with an uneventful vaginal delivery...
December 2016: Revista Brasileira de Ginecologia e Obstetrícia
Yashant Aswani
No abstract text is available yet for this article.
July 2016: Indian Journal of Radiology & Imaging
D W Lee, H N Lee
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
R Raju, O M Abuzeid, O Bolonduro, A Akinpeloye, M Ashraf, M I Abuzeid
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
R E Ruz Barros, L Leroy López, L E Gallardo Valencia, L Ramírez Arreola, A G López Chávez, L L Cruz Sánchez
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
Rajaram Sharma, Amit Kumar Dey, Kartik Mittal, Puneeth Kumar, Hemangini Thakkar
No abstract text is available yet for this article.
October 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
Askin Dogan, Ibrahim Uyar, Gulsah Selvi Demirtas, Atalay Ekin, Ibrahim Gulhan, Ibrahim E Ertas, Mehmet Ozeren
BACKGROUND: We report on an unusual presentation of Herlyn-Werner-Wunderlich syndrome in two 11-year-old girls within a year of menarche. The setting was a training and research hospital. CASE: We present two patients in the pubertal period with cyclic abdominal pain and urinary incontinence who received hysteroscopic septal resection. Menstrual flow was resumed and the complaints of incontinence were eliminated after the hysteroscopic resection of the vaginal septum...
December 2016: Journal of Pediatric and Adolescent Gynecology
Entidhar Al Sawah, Shayne M Plosker, Emad Mikhail
BACKGROUND: Herlyn-Werner-Wunderlich Syndrome (HWWS) is a rare Müllerian anomaly characterized by uterus didelphys coexisting with an obstructed hemivagina and ipsilateral renal agenesis. CASE: A 13-year-old female presented one-year after menarche with severe dysmenorrhea and a right-sided pelvic mass. Imaging identified a right uterus with hematometra, hematocolpos, absent right kidney, normal left kidney, ureter, left uterus, and vagina compressed to the left by right hematocolpos...
July 29, 2016: Surgical Technology International
Salil B Chakrabarti, Maureen P Tigga, Jayanta Ray, Amulya Debbarma
Herlyn-Werner-Wunderlich syndrome is an uncommon variant of mullerian duct anomaly and the approach to its diagnosis requires a high index of suspicion and vigilant work up. Presented here is a case of a 26-year-old woman who had the aforementioned anomaly and was pursued for nearly 10 years to provide her with a fruitful obstetric outcome after having undergone Strassman's metroplasty at a young age of 15 years.
April 2016: Journal of Human Reproductive Sciences
Rohit Bhoil, Ajay Ahluwalia, Narvir Chauhan
Herlyn-Werner-Wunderlich (HWW) syndrome is an uncommon combined müllerian duct anomalies (MDAs) and mesonephric duct malformation of female urogenital tract characterized by uterus didelphys and obstructed hemi-vagina and ipsilateral renal agenesis (OHVIRA) syndrome. We present a rare and unusual case of this syndrome in a 19 year-old female who suffered from hypomenorrhoea and abdominal pain. She had an obstructed hemi-vagina on right side which led to marked distention of ipsilateral cervix, while proximal hemi-vagina compressed the contralateral side causing its partial obstruction resulting in hypomenorrhoea...
April 2016: International Journal of Fertility & Sterility
Rita Mittal
No abstract text is available yet for this article.
April 2016: Journal of Obstetrics and Gynaecology of India
Sofie S F Yung, Siew-Fei Ngu, Vincent Y T Cheung
No abstract text is available yet for this article.
May 2016: International Journal of Gynaecology and Obstetrics
Emel Unal, Hikmet Gulsah Tanyildiz, Murat Sonmezer, Hatice Gul Erkol, Suat Fitoz
Herlyn-Werner-Wunderlich (HWW) syndrome is a rare developmental anomaly that includes uterus didelphys with obstructed hemivagina and ipsilateral renal agenesis. A 13-year-old girl presented with chronic abdominal pain. Magnetic resonance imaging revealed uterus didelphys, hematometrocolpos and renal agenesis on the right side with imperforate hymen. Subsequently the patient was found to have Mullerian duct anomalies. CA 19-9 level was high. At laparoscopy combined with vaginoscopy hematocolpos was drained following which she improved clinically and CA 19-9 level returned to normal...
January 2016: APSP Journal of Case Reports
Niyazi Tug, Mehmet Akif Sargin, Ayhan Çelik, Turgut Alp, Ilter Yenidede
Mullerian malformations result from defective fusion of the Mullerian ducts during development of the female reproductive system and have an incidence of 2-3%. The American Fertility Society classification of Mullerian anomalies is the most commonly utilized standardized classification. The least common form of these malformations is Herlyn-Werner-Wunderlich syndrome characterized by obstructed hemivagina and ipsilateral renal anomaly (OHVIRA). This syndrome has been described with case reports since 1922. Early diagnosis and surgery that include drainage of fluid and resection of the vaginal septum is necessary for OHVIRA to prevent late complications (i...
November 2015: Journal of Clinical and Diagnostic Research: JCDR
Pedro Acién, Maribel Acién
BACKGROUND: Common uterine anomalies are important owing to their impact on fertility, and complex mesonephric anomalies and certain Müllerian malformations are particularly important because they cause serious clinical symptoms and affect woman's quality of life, in addition to creating fertility problems. In these cases of complex female genital tract malformations, a correct diagnosis is essential to avoid inappropriate and/or unnecessary surgery. Therefore, acquiring and applying the appropriate embryological knowledge, management and therapy is a challenge for gynaecologists...
January 2016: Human Reproduction Update
Beatriz Fraga, Catarina Gomes, Raquel Gouveia, Graça Oliveira
A neonate with a prenatal diagnosis of left renal agenesis was born at 33 weeks gestation. A postnatal abdominal ultrasound confirmed the absence of the left kidney and revealed two non-divergent hemiuteri, consistent with the diagnosis of Herlyn-Werner-Wunderlich syndrome. During admission, significant axial hypotonia was noted, warranting additional investigations. Brain ultrasounds and MRI were normal, as were a preliminary metabolic study and comparative genomic hybridisation array. DNA methylation testing confirmed the diagnosis of Prader-Willi syndrome...
2015: BMJ Case Reports
Shibani Mehra, Komal Chamaria, U C Garga, Ankur Kataria, Ashim Ahuja
Herlyn-Werner-Wunderlich (HWW) syndrome is a very rare congenital anomaly of the urogenital tract resulting from maldevelopment of both Mullerian and Wolffian ducts. It is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. It generally presents at puberty shortly following menarche with the symptom of acute pelvic pain. Management of these cases is surgical and consists mainly of vaginoplasty with excision of the vaginal septum in order to release the obstruction and prevent the long term complication of recurrent pyocolpos and infertility...
May 2015: Journal of Clinical and Diagnostic Research: JCDR
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