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https://www.readbyqxmd.com/read/29712949/association-between-maternal-exposure-to-phthalates-and-lower-language-ability-in-offspring-derived-from-hair-metabolome-analysis
#1
Beatrix Jones, Ting-Li Han, Thibaut Delplancke, Elizabeth J McKenzie, Jamie V de Seymour, Mei Chien Chua, Kok Hian Tan, Philip N Baker
The fetus undergoes a crucial period of neurodevelopment in utero. The maternal hair metabolome provides an integrated record of the metabolic state of the mother prior to, and during pregnancy. We investigated whether variation in the maternal hair metabolome was associated with neurodevelopmental differences across infants. Maternal hair samples and infant neurocognitive assessments (using the Bayley III Scales of Infant Development at 24 months) were obtained for 373 infant-mother dyads between 26-28 weeks' gestation from the Growing Up in Singapore Towards Healthy Outcomes cohort...
April 30, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29705122/measurement-of-endocrine-disrupting-and-asthma-associated-chemicals-in-hair-products-used-by-black-women
#2
Jessica S Helm, Marcia Nishioka, Julia Green Brody, Ruthann A Rudel, Robin E Dodson
BACKGROUND: Personal care products are a source of exposure to endocrine disrupting and asthma-associated chemicals. Because use of hair products differs by race/ethnicity, these products may contribute to exposure and disease disparities. OBJECTIVE: This preliminary study investigates the endocrine disrupting and asthma-associated chemical content of hair products used by U.S. Black women. METHODS: We used gas chromatography/mass spectrometry (GC/MS) to test 18 hair products in 6 categories used by Black women: hot oil treatment, anti-frizz/polish, leave-in conditioner, root stimulator, hair lotion, and relaxer...
April 24, 2018: Environmental Research
https://www.readbyqxmd.com/read/29668472/obesity-in-childhood-and-adolescence-genetic-factors
#3
Marko Kostovski, Velibor Tasic, Nevena Laban, Momir Polenakovic, Dragan Danilovski, Zoran Gucev
Obesity and excess weight are a pandemic phenomenon in the modern world. Childhood and adolescent obesity often ends up in obesity in adults. The costs of obesity and its consequences are staggering for any society, crippling for countries in development. Childhood obesity is also widespread in Macedonia. Metabolic syndrome, dyslipidemia and carbohydrate intolerance are found in significant numbers. Parents and grandparents are often obese. Some of the children are either dysmorphic, or slightly retarded. We have already described patients with Prader-Willi syndrome, Bardet-Biedl syndrome or WAGR syndrome...
December 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/29576359/correlation-of-symptoms-to-serum-vitamin-d-levels
#4
Mir Sadat-Ali, Omar N Al Essa, Fawaz M Alani, Hussain K Al Omar, Walid Y Ebrahim
BACKGROUND AND OBJECTIVE: Recent studies have shown that vitamin D plays an important role in many disease processes. However, data is lacking which correlates the common symptoms attributed with vitamin D levels. This study was undertaken to find the correlation of symptoms and Vitamin D levels among ethnic Saudi Arabian population. METHODS: A structured questionnaire was made and translated in the Arabic language, which included, age, weight and height, ethnicity and marital status...
April 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29573447/localized-hypertrichosis-of-intermammary-cleft-in-monozygotic-twins
#5
Daniel Michalik, Carli Whittington, Robert Bednarek, Katherine Marks
Hypertrichosis is a condition in which hair is longer and denser than what is considered normal for an individual based on age, sex, ethnicity, and location on the body and can be classified based on its distribution (generalized vs localized), age of onset (congenital vs acquired), and type of hair (lanugo or vellus vs terminal). We describe a rare case of monozygotic female twins who presented for localized hypertrichosis of the intermammary cleft that developed during puberty. Endocrine examination was unremarkable...
March 24, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29554198/associations-between-maternal-obesity-and-pregnancy-hyperglycemia-and-timing-of-pubertal-onset-in-adolescent-girls-a-population-based-study
#6
Ai Kubo, Julianna Deardorff, Cecile A Laurent, Assiamira Ferrara, Louise C Greenspan, Charles P Quesenberry, Lawrence H Kushi
Early puberty is associated with adverse health outcomes. We investigated whether in utero exposure to maternal obesity is associated with daughters' pubertal timing using 15,267 racially/ethnically diverse Kaiser Permanente Northern California members age 6-11 years with pediatrician-assessed Tanner staging (2003-2017). We extracted maternal body mass index (BMI) during pregnancy from the electronic health record. Using a proportional hazards model with interval censoring we examined the associations between maternal obesity and girl's pubertal timing, and effect modification by race/ethnicity and mediation by pre-pubertal BMI...
March 15, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29548863/scalp-as-a-donor-site-in-children-is-it-really-the-best-option
#7
G van Niekerk, S Adams, H Rode
BACKGROUND: Since 2003 we have used the scalp as a donor site for split skin grafts (SSGs) in major burns when there was a shortage of conventional donor areas. However, we seen a high incidence of complications, contrary to international experience. OBJECTIVE: The aim of this study was to analyze the results and complications related to the scalp as a donor site and to determine whether there is an association between our specific patient population and the complications encountered...
March 13, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29480734/the-persian-cohort-providing-the-evidence-needed-for-healthcare-reform
#8
Sareh Eghtesad, Zahra Mohammadi, Amaneh Shayanrad, Elnaz Faramarzi, Farahnaz Joukar, Behrooz Hamzeh, Mojtaba Farjam, Mohammad Javad Zare Sakhvidi, Mohammadreza Miri-Monjar, Mahmood Moosazadeh, Hamid Hakimi, Salar Rahimi Kazerooni, Bahman Cheraghian, Ali Ahmadi, Azim Nejatizadeh, Iraj Mohebbi, Farhad Pourfarzi, Farzin Roozafzai, Nazgol Motamed-Gorji, Seyed Ali Montazeri, Sahar Masoudi, Masoumeh Amin-Esmaeili, Navid Danaie, Seyed Reza Mirhafez, Hasan Hashemi, Hossein Poustchi, Reza Malekzadeh
In the past, communicable diseases caused the highest mortality in Iran. Improvements in socioeconomic status and living standards including access to safe drinking water, along with the inception of Health Houses in the 1980s, have changed disease patterns, decreasing the spread of and deaths from infectious and communicable diseases. The incidence and prevalence of non-communicable diseases (NCD), however, have now increased in Iran, accounting for nearly 80% of deaths and disabilities. Without interventions, NCD are predicted to impose a substantial human and economic burden in the next 2 decades...
November 1, 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29454168/genetic-and-environmental-influences-on-pubertal-hormones-in-human-hair-across-development
#9
Andrew D Grotzinger, Daniel A Briley, Laura E Engelhardt, Frank D Mann, Megan W Patterson, Jennifer L Tackett, Elliot M Tucker-Drob, K Paige Harden
Puberty is a complex biopsychosocial process that can affect an array of psychiatric and medical disorders emerging in adolescence. Although the pubertal process is driven by neuroendocrine changes, few quantitative genetic studies have directly measured puberty-relevant hormones. Hair samples can now be assayed for accumulation of hormones over several months. In contrast to more conventional salivary measures, hair measures are not confounded by diurnal variation or hormonal reactivity. In an ethnically and socioeconomically diverse sample of 1286 child and adolescent twins and multiples from 672 unique families, we estimated genetic and environmental influences on hair concentrations of testosterone, DHEA, and progesterone across the period of 8-18 years of age...
April 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29450217/a-cross-sectional-assessment-of-cutaneous-lumbosacral-and-coccygeal-physical-examination-findings-in-a-healthy-newborn-population
#10
Janelle Aby, Juliann Lipps Kim
Objective. The purpose of this study is to describe the range and frequency of cutaneous lumbosacral and coccygeal findings encountered during the newborn examination in a population of apparently healthy babies, to determine if the prevalence of these findings is associated with race/ethnicity, and to report the frequency of co-occurrence of low-risk cutaneous findings. Methods . Lumbosacral physical findings of 1121 infants were documented on well newborns at least 35 weeks or greater gestational age under the authors' care...
2018: Global Pediatric Health
https://www.readbyqxmd.com/read/29441597/toxic-stress-and-protective-factors-in-multi-ethnic-school-age-children-a-research-protocol
#11
Eileen M Condon, Lois S Sadler, Linda C Mayes
Exposure to stressful environments in early childhood can cause a toxic stress response and lead to poor health outcomes, including obesity, cardiac disease, diabetes, and mental illness. In animals and maltreated children, the presence of a nurturing caregiver can buffer against the physiological disruptions associated with a toxic stress response; however, the specific caregiver and parenting characteristics that best promote a protective relationship in humans remain largely unexplored, particularly in families living in high-risk environments...
April 2018: Research in Nursing & Health
https://www.readbyqxmd.com/read/29396081/girls-sleep-trajectories-across-the-pubertal-transition-emerging-racial-ethnic-differences
#12
Lindsay Till Hoyt, Julianna Deardorff, Kristine Marceau, Cecile A Laurent, Gayle C Windham, Louise C Greenspan, Susan M Pinney, Susan Teitelbaum, Kevin J Grimm, Melissa J Hagan, Frank M Biro, Mary S Wolff, Lawrence H Kushi, Robert A Hiatt
PURPOSE: This study aims to examine the longitudinal association between puberty and sleep in a diverse sample of girls and explore racial/ethnic differences in this association. METHODS: Using latent growth curve modeling, the present study measured pubertal development (timing and rate) and sleep (wake time and bedtime) in 1,239 socioeconomically and ethnically diverse girls starting when they were 6-8 years old and followed longitudinally for up to 8 years. Pubertal assessment was conducted annually in clinic by physical examination, classified by sexual maturation stage for breast and pubic hair development by trained raters...
April 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/29388286/evaluation-of-childhood-nutrition-by-dietary-survey-and-stable-isotope-analyses-of-hair-and-breath
#13
Luciano O Valenzuela, Shannon P O'Grady, Lindsey E Enright, Maureen Murtaugh, Carol Sweeney, James R Ehleringer
OBJECTIVES: The natural abundances of carbon, nitrogen, and sulfur stable isotopes in hair, and of carbon isotopes in breath serve as quantitative biomarkers of protein and carbohydrate sources, but applicability of isotopes for evaluating children's diet has not been demonstrated. In this study, we sought to describe the stable isotope patterns observed in the hair and breath of children and to assess dietary variations in relation to age and ethnicity, hypothesizing that these would reflect dietary differences across age and ethnic groups and would correlate with intake variables derived from a Food Frequency Questionnaire...
February 1, 2018: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/29372330/pre-incubation-in-soil-improves-the-nitrogen-fertiliser-value-of-hair-waste
#14
N M Malepfane, P Muchaonyerwa
Global generation of human hair waste and its disposal at landfills could contribute to the leaching of nitrates into ground water. High concentrations of nitrogen (N) and other elements suggest that the waste could be a source of plant nutrients and differences in ethnic hair types could affect nutrient release and fertiliser value. The objective of this study was to determine the effects of hair type, as an N source, and pre-incubation time on dry-matter yield, nutrient uptake by spinach (Spinacia oleracea L...
January 25, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29315502/a-genome-wide-association-study-identifies-a-candidate-gene-associated-with-atazanavir-exposure-measured-in-hair
#15
Bani Tamraz, Yong Huang, Audrey L French, Seble Kassaye, Kathryn Anastos, Marek J Nowicki, Stephen Gange, Deborah R Gustafson, Peter Bacchetti, Ruth M Greenblatt, Pirro G Hysi, Bradley E Aouizerat
Hair provides a direct measure of long-term exposure of atazanavir (ATV). We report the results of the first genome-wide association study (GWAS) of ATV exposure measured in hair in an observational cohort representative of US women living with HIV; the Women's Interagency HIV Study. Approximately 14.1 million single nucleotide polymorphisms (SNPs) were analyzed in linear regression-based GWAS, with replication, adjusted for nongenetic predictors collected under conditions of actual use of ATV in 398 participants...
January 9, 2018: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29301538/hair-product-use-age-at-menarche-and-mammographic-breast-density-in-multiethnic-urban-women
#16
Jasmine A McDonald, Parisa Tehranifar, Julie D Flom, Mary Beth Terry, Tamarra James-Todd
BACKGROUND: Select hair products contain endocrine disrupting chemicals (EDCs) that may affect breast cancer risk. We hypothesize that, if EDCs are related to breast cancer risk, then they may also affect two important breast cancer risk factors: age at menarche and mammographic breast density. METHODS: In two urban female cohorts (N = 248): 1) the New York site of the National Collaborative Perinatal Project and 2) the New York City Multiethnic Breast Cancer Project, we measured childhood and adult use of hair oils, lotions, leave-in conditioners, root stimulators, perms/relaxers, and hair dyes using the same validated questionnaire...
January 4, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29273420/allergens-of-permanent-hair-dyes-induces-epidermal-damage-skin-barrier-loss-and-il-1-%C3%AE-increase-in-epidermal-in-vitro-model
#17
Thalita Boldrin Zanoni, Tatiana Nascimento Pedrosa, Carolina Motter Catarino, Sander W Spiekstra, Danielle Palma de Oliveira, Gertjan Den Hartog, Aalt Bast, Geja Hagemann, Susan Gibbs, Silvia Berlanga de Moraes Barros, Silvya Stuchi Maria-Engler
Allergic and irritant skin reactions caused by topical exposure to permanent hair dyes are a common problem. For regulatory and ethnical purposes, it is required to perform chemical safety assessment following the replacement, reduction, and refinement of animal testing (3Rs). Permanent hair dyes are formed by a mixture of ingredients that vary from low to extreme skin sensitizing potency and that inter-react to form unknown by-products. Because of the complex reaction, this cytotoxic mechanism has not yet been elucidated and is the subject of this study...
February 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29241771/alopecia-areata-disease-characteristics-clinical-evaluation-and-new-perspectives-on-pathogenesis
#18
REVIEW
Lauren C Strazzulla, Eddy Hsi Chun Wang, Lorena Avila, Kristen Lo Sicco, Nooshin Brinster, Angela M Christiano, Jerry Shapiro
Alopecia areata (AA) is a common, inflammatory, nonscarring type of hair loss. Significant variations in the clinical presentation of AA have been observed, ranging from small, well-circumscribed patches of hair loss to a complete absence of body and scalp hair. Patients affected by AA encompass all age groups, sexes, and ethnicities, and may experience frustration with the unpredictable nature of their disease for which there is currently no definitive treatment. The cause of AA remains incompletely understood, though it is believed to result-at least in part-from a loss of immune privilege in the hair follicle, autoimmune-mediated hair follicle destruction, and the upregulation of inflammatory pathways...
January 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29240822/acne-keloidalis-nuchae-in-asian-a-single-institutional-experience
#19
Kiyong Na, Sang Ho Oh, Sang Kyum Kim
Acne keloidalis nuchae, a type of folliculitis involving the back of the neck, is common in black men, although rare cases have been reported in patients of other ethnicities. We analyzed the clinicopathological features of acne keloidalis nuchae in 17 Asians. Patients' age at the time of presentation ranged from 20 to 69 years. Most patients experienced the disease over 2 years (range, 3 months-20 years); follow-up data were available for 11 (65%) patients (range, 2-95 months). Nine (53%) patients had comorbidities, but none had a history of other skin disease or a family history of acne keloidalis nuchae...
2017: PloS One
https://www.readbyqxmd.com/read/29230660/dietary-intake-of-soy-and-cruciferous-vegetables-and-treatment-related-symptoms-in-chinese-american-and-non-hispanic-white-breast-cancer-survivors
#20
Sarah J O Nomura, Yi-Ting Hwang, Scarlett Lin Gomez, Teresa T Fung, Shu-Lan Yeh, Chiranjeev Dash, Laura Allen, Serena Philips, Leena Hilakivi-Clarke, Yun-Ling Zheng, Judy Huei-Yu Wang
PURPOSE: This project was undertaken to examine the association between dietary intake of soy or cruciferous vegetables and breast cancer treatment-related symptoms among Chinese-American (CA) and Non-Hispanic White (NHW) breast cancer survivors. METHODS: This cross-sectional study included 192 CA and 173 NHW female breast cancer survivors (stages 0-III, diagnosed between 2006 and 2012) recruited from two California cancer registries, who had completed primary treatment...
April 2018: Breast Cancer Research and Treatment
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