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Ana Fernández-Araque, Andrea Giaquinta Aranda, Consuelo Laudo Pardo, Abel Rojo Aragüés
Introducción: la influencia de los antioxidantes en los procesos oculares ha tomado en los últimos años una relevancia importante por sus efectos en la salud visual. El estrés oxidativo es un factor implicado en el desarrollo de las principales patologías tales como cataratas, glaucoma y degeneración macular asociada a la edad (DMAE).Objetivo: establecer la evidencia científica que existe sobre los distintos tipos de antioxidantes y sus efectos en procesos patológicos oculares mediante una revisión sistemática...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Christopher Bullister
No abstract text is available yet for this article.
March 2017: Radiologic Technology
Stephen A Geraci, S Calvin Thigpen
Many believe that mentoring is essential for new and developing faculty physicians to achieve their professional and personal goals, yet there are both positive and potential negative aspects of mentoring. Research reports on the process have few quantifiable objective outcomes, use mostly single-center study populations, lack controls and use mostly qualitative techniques. Absence of a standardized definition of mentorship has allowed widespread application of the term to other forms of protégé support. Several models have been developed, with other generalized descriptors used to differentiate the important qualities of mentoring relationships...
February 2017: American Journal of the Medical Sciences
Susan M Downey, Stephen A Geraci
Publications in peer-reviewed biomedical journals are essential for sharing knowledge and advancing healthcare. This article will articulate a 5-step approach for developing and publishing a manuscript, and provide academic clinicians with an instructional tool they can provide to their protégés and junior faculty. The authors attempt to distill existing advice for preparing manuscripts, which is found in myriad formats, combine these tutorials with their collective experience and present this approach for developing and publishing successfully a manuscript in a peer-reviewed journal...
February 2017: American Journal of the Medical Sciences
Pan Wu, Dan Wan, Gudan Xu, Gui Wang, Hongmin Ma, Tingting Wang, Yaojie Gao, Jianzhao Qi, Xiaoxia Chen, Jian Zhu, Yong-Quan Li, Zixin Deng, Wenqing Chen
Pentostatin (PTN, deoxycoformycin) and arabinofuranosyladenine (Ara-A, vidarabine) are purine nucleoside antibiotics used clinically to treat hematological cancers and human DNA virus infections, respectively. PTN has a 1,3-diazepine ring, and Ara-A is an adenosine analog with an intriguing epimerization at the C-2' hydroxyl group. However, the logic underlying the biosynthesis of these interesting molecules has long remained elusive. Here, we report that the biosynthesis of PTN and Ara-A employs an unusual protector-protégé strategy...
January 12, 2017: Cell Chemical Biology
Sara Dubois, Nicole Fenwick, Erin A Ryan, Liv Baker, Sandra E Baker, Ngaio J Beausoleil, Scott Carter, Barbara Cartwright, Federico Costa, Chris Draper, John Griffin, Adam Grogan, Gregg Howald, Bidda Jones, Kate E Littin, Amanda T Lombard, David J Mellor, Daniel Ramp, Catherine A Schuppli, David Fraser
Human-wildlife conflicts are commonly addressed by excluding, relocating, or lethally controlling animals with the goal of preserving public health and safety, protecting property, or conserving other valued wildlife. However, declining wildlife populations, a lack of efficacy of control methods in achieving desired outcomes, and changes in how people value animals have triggered widespread acknowledgment of the need for ethical and evidence-based approaches to managing such conflicts. We explored international perspectives on and experiences with human-wildlife conflicts to develop principles for ethical wildlife control...
January 16, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
R H F Hunter
The contribution of Charles Thibault in creating and developing a major international centre of animal research at Jouy-en-Josas (near Versailles) in post Second World War France is recorded in detail. Not only did he select a team of gifted young chercheurs, but he stimulated and supported their research in diverse ways. The projects covered were not only primarily of significance to animal reproduction, but they also became relevant to human infertility studies and to IVF treatments. Members of the team in Physiologie Animale gained international research reputations and seasoned overseas researchers were attracted to Jouy-en-Josas for their sabbaticals...
February 2017: Zygote: the Biology of Gametes and Early Embryos
Lonneke M JanssenDuijghuijsen, Jaap Keijer, Marco Mensink, Kaatje Lenaerts, Lars Ridder, Stefan Nierkens, Shirley W Kartaram, Martie C M Verschuren, Raymond H H Pieters, Richard Bas, Renger F Witkamp, Harry J Wichers, Klaske van Norren
What is the central question of this study? Exercise is known to induce stress-related physiological responses, such as changes in intestinal barrier function. Our aim was to determine the test-retest repeatability of these responses in well-trained individuals. What is the main finding and its importance? Responses to strenuous exercise, as indicated by stress-related markers such as intestinal integrity markers and myokines, showed high test-retest variation. Even in well-trained young men an adapted response is seen after a single repetition after 1 week...
January 1, 2017: Experimental Physiology
Curtis G Tribble
In helping to organize many different educational environments in the School of Medicine and the Department of Surgery at the University of Virginia over the last 30 years, my colleagues and I have long recognized that our students and trainees, while uniformly well prepared academically for their respective missions, often take inadequate care of themselves. Everyone who has flown on a plane will recall that the flight attendants always tell passengers that, if oxygen is needed, one must put one's own mask on first, before helping others put their masks on...
October 31, 2016: Heart Surgery Forum
Lonneke M JanssenDuijghuijsen, Marco Mensink, Kaatje Lenaerts, Ewa Fiedorowicz, Dorien A M van Dartel, Jurriaan J Mes, Yvette C Luiking, Jaap Keijer, Harry J Wichers, Renger F Witkamp, Klaske van Norren
Exercise is one of the external factors associated with impairment of intestinal integrity, possibly leading to increased permeability and altered absorption. Here, we aimed to examine to what extent endurance exercise in the glycogen-depleted state can affect intestinal permeability toward small molecules and protein-derived peptides in relation to markers of intestinal function. Eleven well-trained male volunteers (27 ± 4 years) ingested 40 g of casein protein and a lactulose/rhamnose (L/R) solution after an overnight fast in resting conditions (control) and after completing a dual - glycogen depletion and endurance - exercise protocol (first protocol execution)...
October 2016: Physiological Reports
Wanda Montalvo, Mary W Byrne
Objective. The aim of this study was to describe and analyze the correlations between mentoring functions and political skill development among nurses who have earned or are candidates for a Ph.D. or doctorate of nursing practice (DNP) degree. Background. The healthcare system is in flux; future generations of Ph.D. and DNP nurse leaders will be required to demonstrate political acumen. Political skill to navigate organizational politics has had limited research within nursing. Methods. A cross-sectional research design using a web-based survey of 222 nurses who have earned or are candidates for a Ph...
2016: Nursing Research and Practice
Pilar Bueno Vargas, Manuel Manzano Martín, Inmaculada López-Aliaga, José M ª López Pedrosa
Introducción: la gestación y lactancia están relacionadas con pérdidas temporales en la densidad mineral ósea (DMO) materna. Una suplementación con calcio podría resultar beneficiosa para evitar la pérdida de masa ósea del esqueleto materno. Otros nutrientes como los prebióticos han sido identificados como responsables de un incremento en la absorción de minerales, pudiendo condicionar la mineralización ósea.Objetivo: estudiar el efecto de la suplementación de la dieta materna con el prebiótico inulina enriquecida con oligofructosa, durante la gestación y la lactancia sobre el contenido mineral óseo (CMO) y la DMO al final del periodo de lactancia...
September 20, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Bill Jenkins
The duck-billed platypus, or Ornithorhynchus, was the subject of an intense debate among natural historians in the late eighteenth and early nineteenth centuries. Its paradoxical mixture of mammalian, avian and reptilian characteristics made it something of a taxonomic conundrum. In the early 1820s Robert Jameson (1774-1854), the professor of natural history at the University of Edinburgh and the curator of the University's natural history museum, was able to acquire three valuable specimens of this species...
October 2016: Annals of Science
Shannon M Varga, Nancy L Deutsch
No abstract text is available yet for this article.
September 27, 2016: Journal of Primary Prevention
Shannon M Varga, Nancy L Deutsch
Mentoring continues to be a popular intervention for promoting positive youth development. However, the underlying mechanisms associated with sustainable and successful relationships remain largely unknown. Our study aimed to expand on previous literature by examining characteristics that have previously been linked to mentoring outcomes (e.g., authenticity, empathy), from a process-focused lens. We utilized post program satisfaction scores and interviews to examine the presence of each characteristic in a large sample of dyads (n = 144) as well as dyads' levels of agreement or disagreement about aspects of the relationships...
October 2016: Journal of Primary Prevention
Kais Tahar, Michael Schaaf, Franziska Jahn, Christian Kücherer, Barbara Paech, Heinrich Herre, Alfred Winter
The increasing number of terms used in textbooks for information management (IM) in hospitals makes it difficult for medical informatics students to grasp IM concepts and their interrelations. Formal ontologies which comprehend and represent the essential content of textbooks can facilitate the learning process in IM education. The manual construction of such ontologies is time-consuming and thus very expensive [3]. Moreover, most domain experts lack skills in using a formal language like OWL [2] and usually have no experience with standard editing tools like Protégé <fnr rid="fn001" /><fn id="fn001">http://protege...
2016: Studies in Health Technology and Informatics
Claire L Gordon, Chunhua Weng
This article describes the Bacterial Infectious Diseases Ontology (BCIDO) dataset related to research published in 10.1016/j.jbi.2015.07.014 [1], and contains the Protégé OWL files required to run BCIDO in the Protégé environment. BCIDO contains 1719 classes and 39 object properties.
September 2016: Data in Brief
Cheng Chen, Peng Wen
The aim of the present study was to investigate the effect of mentoring on protégés' organizational deviance. The sample comprised 202 ongoing formal mentoring dyads in the People's Republic of China (mentor samples: 61.9% male, M age = 36.8 years; protégé samples: 57.4% male, M age = 25.0 years). The regression results showed that mentoring was negatively related to protégés' organizational deviance. Moreover, job embeddedness and organizational identification mediated the association between mentoring and protégés' organizational deviance...
August 2016: Psychological Reports
Christopher Ochs, James Geller, Yehoshua Perl, Mark A Musen
Software tools play a critical role in the development and maintenance of biomedical ontologies. One important task that is difficult without software tools is ontology quality assurance. In previous work, we have introduced different kinds of abstraction networks to provide a theoretical foundation for ontology quality assurance tools. Abstraction networks summarize the structure and content of ontologies. One kind of abstraction network that we have used repeatedly to support ontology quality assurance is the partial-area taxonomy...
August 2016: Journal of Biomedical Informatics
Ji-Hyun Lee, Hyeoun-Ae Park, Tae-Min Song
The purpose of this study is to develop a low fertility ontology for collecting and analyzing social data. A low fertility ontology was developed according to Ontology Development 101 and formally represented using Protégé. The content coverage of the ontology was evaluated using 1,387 narratives posted by the public and 63 narratives posted by public servants. Six super-classes of the ontology were developed based on Bronfenbrenner's ecological system theory with an individual in the center and environmental systems impacting their as surroundings...
2016: Studies in Health Technology and Informatics
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