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https://www.readbyqxmd.com/read/29024799/treatment-for-uterine-isthmocele-a-pouch-like-defect-at-the-site-of-cesarean-section-scar
#1
REVIEW
Antonio Setubal, João Alves, Filipa Osório, Adalgisa Guerra, Rodrigo Fernandes, Jaime Albornoz, Zacharoula Sidiroupoulou
Isthmocele appears as a fluid pouch-like defect in the anterior uterine wall at the site of a prior Cesarean section and ranges in prevalence from 19% to 84%, a direct relation to the increase in Cesarean sections performed worldwide. Many definitions have been suggested for the dehiscence resulting from Cesarean section, and we propose standardization with a single term for all cases: isthmocele. Patients are not always symptomatic, but symptoms typically include intermittent abnormal bleeding, pain, and infertility...
October 9, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29022920/the-lncrna-tug1-modulates-proliferation-in-trophoblast-cells-via-epigenetic-suppression-of-rnd3
#2
Yetao Xu, Zhiping Ge, Erbao Zhang, Qing Zuo, Shiyun Huang, Nana Yang, Dan Wu, Yuanyuan Zhang, Yanzi Chen, Haoqin Xu, Huan Huang, Zhiyan Jiang, Lizhou Sun
Due to limited treatment options, pre-eclampsia (PE) is associated with fetal perinatal and maternal morbidity and mortality. During the causes of PE, failure of uterine spiral artery remodeling which might be related to functioning abnormally of trophoblast cells, result in the occurrence and progression of PE. Recently, abnormal expression of long non-coding RNAs (lncRNAs), as imperative regulators involved in human diseases progression (included PE), which has been indicated by increasing evidence. In this research, we found that TUG1, a lncRNA, was markedly reduced in placental samples from patients with PE...
October 12, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/29022077/no-association-between-periodontitis-and-preterm-low-birth-weight-a-case-control-study
#3
Mariana Fampa Fogacci, Elaine de O C Cardoso, Davi da S Barbirato, Denise Pires de Carvalho, Carmelo Sansone
PURPOSE: This study aimed to investigate the association between periodontitis in pregnant women and adverse pregnancy outcomes by heeding confounding risk factors for preterm low birth weight infants. METHODS: This study was reported according to The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement. A case-control study was conducted. Medical records of all pregnant women attending a prenatal care clinic were screened. Those between 21 and 34 years and gestational age of 28-32 weeks were initially enrolled in the study...
October 11, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28994515/role-of-pelvic-ultrasound-simulation
#4
Sushila Arya, Zuber D Mulla, Sanja Kupesic Plavsic
BACKGROUND: Pelvic ultrasound is a critical diagnostic imaging tool in obstetrics and gynaecology. Training opportunities in transvaginal ultrasound have not kept pace with the demand among learners because of the increased complexity of modern ultrasound technology and duty-hour restrictions. Ultrasound simulation training has the potential to overcome this gap. Training opportunities in transvaginal ultrasound have not kept pace with the demand OBJECTIVE: Our study aimed to determine the usefulness, applicability and attitudes toward pelvic ultrasound simulation training among residents, sonographers and practising doctors...
October 10, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28993358/novel-management-of-a-giant-cervical-myoma-in-a-premenopausal-patient
#5
Jolene Wong, Grace Hwei Ching Tan, Ravichandran Nadarajah, Melissa Teo
Cervical myomas are rare and account for <1% of uterine leiomyomas. Clinical complications include bulk-related symptoms of pelvic pain, abnormal bleeding and infertility. While hysterectomies may be readily performed for postmenopausal women; the management of women with cervical myomas of childbearing age remains a challenge.Traditionally described fertility-preserving procedures such as myomectomy, endometrial ablation or myolysis may only be applied to leiomyomas within the uterine corpus. Little is known about the surgical management of its cervical counterpart...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28982650/incidental-detection-of-maternal-neoplasia-in-noninvasive-prenatal-testing
#6
Nilesh G Dharajiya, Daniel S Grosu, Daniel H Farkas, Ron M McCullough, Eyad Almasri, Youting Sun, Sung K Kim, Taylor J Jensen, Juan-Sebastian Saldivar, Eric J Topol, Dirk van den Boom, Mathias Ehrich
BACKGROUND: Noninvasive prenatal testing (NIPT) uses cell-free DNA (cfDNA)(5) as an analyte to detect copy-number alterations in the fetal genome. Because maternal and fetal cfDNA contributions are comingled, changes in the maternal genome can manifest as abnormal NIPT results. Circulating tumor DNA (ctDNA) present in cases of maternal neoplasia has the potential to distort the NIPT readout to a degree that prevents interpretation, resulting in a nonreportable test result for fetal aneuploidy...
October 5, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28964685/shunt-based-interventions-why-how-and-when-to-place-a-shunt
#7
REVIEW
Mark P Johnson, R Douglas Wilson
The broad categories of surgical fetal therapy can be separated into either open surgical techniques or minimally invasive endoscopic/ultrasound-guided techniques that require only puncture of the uterus with single or multiple small ports. Benefits of fetoscopic or ultrasound-guided fetal intervention include decreased uterine irritability, decreased incidence of preterm labor, and avoidance of risks associated with hysterotomy and commitment to cesarean delivery for future pregnancies. Fetal abnormalities potentially amenable to ultrasound-guided drainage techniques include thoracic fluid-filled lesions and lower urinary tract obstruction...
September 27, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28963923/pro-inflammatory-m1-th1-type-immune-network-and-increased-expression-of-tsg-6-in-the-eutopic-endometrium-from-women-with-endometriosis
#8
M Matteo, E Cicinelli, M Neri, R Carrubba, F A Carpagnano, F Romeo, G Scutiero, P Greco, C Garlanda, G Vendemiale, P E Levi Setti, G Serviddio
OBJECTIVE: The study aimed to explore the type 1 and type 2 cytokines expression in the endometrium from women affected by endometriosis compared to controls. The expression of TSG-6, a multifunctional protein involved in several inflammatory disease, was also evaluated. Study Design SETTING: Experimental clinical study. PATIENTS: 10 patients affected by endometriosis and 11 controls. INTERVENTIONS: Patients underwent to an ultrasound transvaginal examination and a diagnostic hysteroscopy in order to exclude any uterine abnormality...
September 7, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28963728/diagnostic-accuracy-of-ultrasound-in-detecting-the-severity-of-abnormally-invasive-placentation-a-systematic-review-and-meta-analysis
#9
REVIEW
Giorgio Pagani, Giuseppe Cali, Ganesh Acharya, Ilan Timor Trisch, Jose Palacios-Jaraquemada, Alessandra Familiari, Danilo Buca, Lamberto Manzoli, Maria Elena Flacco, Francesco Fanfani, Marco Liberati, Giovanni Scambia, Francesco D'Antonio
INTRODUCTION: Our objective was to elucidate the overall diagnostic accuracy of ultrasound in detecting the severity of abnormally invasive placentation (AIP). MATERIAL AND METHODS: Medline, Embase, CINAHL and The Cochrane databases were searched. The ultrasound signs explored were: loss of hypoechoic (clear) zone in the placental-uterine interface, placental lacunae, bladder wall interruption, myometrial thinning, focal exophitic mass, placental lacunar flow, sub-placental vascularity, and uterovescical hypervascularity...
September 30, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28963562/association-between-exposure-to-air-pollution-during-pregnancy-and-false-positives-in-fetal-heart-rate-monitoring
#10
Seiichi Morokuma, Takehiro Michikawa, Shin Yamazaki, Hiroshi Nitta, Kiyoko Kato
Fetal heart rate (FHR) monitoring is essential for fetal management during pregnancy and delivery but results in many false-positive diagnoses. Air pollution affects the uterine environment; thus, air pollution may change FHR reactivity. This study assessed the association between exposure to air pollution during pregnancy and FHR monitoring abnormalities using 2005-2010 data from the Japan Perinatal Registry Network database. Participants were 23,782 singleton pregnant women with FHR monitoring, without acidemia or fetal asphyxia...
September 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28960053/an-overview-of-the-results-of-hysterosonography-prior-to-in-vitro-fertilization
#11
Vinicius Medina Lopes, Jean Pierre Barguil, Thaísa Sant'Anna Lacerda, Anna Luíza Moraes Souza, Aluísio Mendes da Rocha Filho, Mariana Fonseca Roller, Eleonora Araújo Barbosa, Natalia Zavattiero Tierno, Joaquim Roberto Costa Lopes
OBJECTIVE: This study aimed to analyze the results of hysterosonography performed prior to in vitro fertilization (IVF) and to correlate anomalous findings with hysteroscopy. METHODS: Findings from 197 hysterosonograms of patients examined in an assisted reproduction clinic between January 2012 and August 2014 were included. Enrollment criteria: patients in preparation for IVF not recently submitted to uterine examination through hysterosalpingography or hysteroscopy referred to hysterosonography...
September 29, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28944967/risk-for-chromosomal-aberrations-in-apparently-isolated-intra-uterine-growth-restriction-a-systematic-review
#12
REVIEW
Lena Sagi-Dain, Amir Peleg, Shlomi Sagi
OBJECTIVE: To perform a systematic review examining the risk of chromosomal aberrations in apparently isolated intra-uterine growth restriction (IUGR). METHODS: Search was conducted by research librarian in five databases. By independent screening of 2894 references, two investigators selected original studies examining the risk of chromosomal aberrations in apparently isolated IUGR diagnosed at the second and third trimesters using ultrasound. We excluded studies describing IUGR combined with additional fetal anomalies detected by ultrasound and those where fetuses with structural anomalies or aneuploidy were not reported...
September 25, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28939480/title-hysteroscopic-removal-of-retained-products-of-conception-implanted-over-a-focal-area-of-adenomyosis-a-case-report
#13
Luis Alonso, Laura Nieto, Jose Carugno
STUDY OBJECTIVE: To describe a technique for hysteroscopic removal of retained products of conception (RPOC) implanted over an area of adenomyosis. DESIGN: Case report (Canadian Task Force classification III) SETTING: Retained products of conception is an unfortunate complication that may occur after resolution of a normal pregnancy, being more common after early pregnancy termination or spontaneous miscarriage. (1) Immediate consequences of RPOC include persistent vaginal bleeding, abdominal pain, pelvic infection, fever and dilated cervix...
September 19, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28937267/surface-transperineal-ultrasound-and-vaginal-abnormalities-applications-and-strengths
#14
Soha Talaat Hamed, Sahar Mahmoud Mansour
The role of ultrasound in the assessment of the female pelvis whether using transabdominal/ transluminal approach is well established. Little reported about the use of the superficial transperineal approach that could provides full assessment of the lower cervix and vagina which may be overlooked in the standard examinations. Proximity of the probe to the vagina helps not just the detection of organ abnormalities yet also proper characterization and differentiation of vaginal masses. Advances in Knowledge: The indications, technique of scanning and limitations of transperineal ultrasound in the evaluation of the lower uterine segment...
September 13, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28934813/postpartum-retained-products-of-conception-a-novel-approach-to-follow-up-and-early-diagnosis
#15
Noam Smorgick, Ayala Krakov, Ron Maymon, Moshe Betser, Josef Tovbin, Moty Pansky
Purpose To investigate whether ultrasound follow-up for the detection of postpartum retained products of conception (RPOC) in women considered at risk for this condition may allow for early diagnosis. Methods Parturients at risk for RPOC underwent an ultrasound exam on the second postpartum day. Based on the ultrasound findings, women were either: (1) discharged to routine postpartum care in cases of normal scans, (2) invited for follow-up in cases of abnormal scans. We retrospectively analyzed the rates of women requiring uterine evacuation due to persistent abnormal scans...
September 21, 2017: Ultraschall in der Medizin
https://www.readbyqxmd.com/read/28927797/the-decline-of-pregnancy-rate-and-abnormal-uterine-responsiveness-of-steroid-hormones-in-aging-mice
#16
Meng-Qi Li, Mei-Nan Yao, Jia-Qi Yan, Zi-Long Li, Xiao-Wei Gu, Shuai Lin, Wei Hu, Zeng-Ming Yang
Reproductive capacity in animals and women declines with increasing age. Although ovarian aging is considered as a main cause for the decline of pregnancy rate, whether uterine aging occurs remains unclear. Even if blastocysts are transferred from young donors to older pseudopregnant recipients, the rate of implantation is still low, suggesting the occurrence of uterine aging. In this study, we compared the pregnancy rate and the uterine responsiveness of steroid hormones in ovariectomized mice at age between 2- and 12-month-old...
September 16, 2017: Reproductive Biology
https://www.readbyqxmd.com/read/28924270/clinical-efficacy-of-levonorgestrel-and-norethisterone-for-the-treatment-of-chronic-abnormal-uterine-bleeding
#17
Muhammad Nadeem Ashraf, Agha Habib-Ur-Rehman, Zahid Shehzad, Shakir DakheelAllah AlSharari, Ghulam Murtaza
OBJECTIVE: To compare the clinical efficacy of levonorgestrel intrauterine system with oral norethisterone for the treatment of idiopathic chronic abnormal uterine bleeding. METHODS: This cross-sectional study was conducted at Bahawal Victoria Hospital, Jubilee Female Hospital, Civil Hospital and private clinics of consultant gynaecologists in Bahawalpur, Pakistan, from March to August 2014, and comprised patients presenting with abnormal uterine bleeding. The patients were equally and randomly divided into two groups, i...
September 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28919691/molecular-etiopathology-of-naturally-occurring-reproductive-diseases-in-female-goats
#18
V Beena, R V S Pawaiya, K Gururaj, D D Singh, A K Mishra, N K Gangwar, V K Gupta, R Singh, A K Sharma, M Karikalan, Ashok Kumar
AIM: The aim of the present study was to investigate the molecular etiopathology of occurrence of reproductive diseases in female goats. Reproductive diseases in goats account for major economic losses to goat farmers in terms of valuable loss of offspring and animal productivity. MATERIALS AND METHODS: A total of 660 female genitalia were examined for pathological conditions (macroscopic and microscopic lesions). The etiopathological study was carried out for the presence of pathogenic organisms such as Brucella, Chlamydia, and Campylobacter in the uterus and ovary...
August 2017: Veterinary World
https://www.readbyqxmd.com/read/28919146/m%C3%A3-llerian-agenesis-in-cat-eye-syndrome-and-22q11-chromosome-abnormalities-a-case-report-and-literature-review
#19
Abdulmajeed AlSubaihin, John VanderMeulen, Kate Harris, John Duck, Elizabeth McCready
BACKGROUND: Although Müllerian agenesis is the second most common cause of primary amenorrhea the underlying etiology in the majority of cases is unknown. Müllerian agenesis has been reported as a rare finding associated with chromosomal aberrations of the 22q11 chromosomal region including at least one individual with cat eye syndrome (CES) and 10 individuals with deletions or duplications of the 22q11.2 region. However, a potential link between 22q11 abnormalities and uterine malformations has been difficult to adequately ascertain given the limited case reports in the literature...
September 14, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28916305/unusual-causes-of-venous-thrombosis-bladder-distension-and-uterine-mass
#20
Michael L Caparelli, Sepehr Lalezari, Steven Perlman
Thrombosis of the inferior vena cava (IVC) continues to be a rare event and there is a scarcity of evidence with regard to its etiology. One source for IVC thrombosis is external compression from adjacent structures. In this case series we present one case of IVC thrombosis caused by a severely distended bladder and a case of external iliac thrombosis caused by external compression from an abnormally enlarged uterus. The treatment of each case is varied and included novel oral anticoagulation (NOAC), catheter-directed thrombolysis in conjunction with mechanical thrombectomy, or a combination of these...
September 12, 2017: Annals of Vascular Surgery
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