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https://www.readbyqxmd.com/read/28549234/lesion-characteristics-driving-right-hemispheric-language-reorganization-in-congenital-left-hemispheric-brain-damage
#1
Karen Lidzba, Bianca de Haan, Marko Wilke, Ingeborg Krägeloh-Mann, Martin Staudt
Pre- or perinatally acquired ("congenital") left-hemispheric brain lesions can be compensated for by reorganizing language into homotopic brain regions in the right hemisphere. Language comprehension may be hemispherically dissociated from language production. We investigated the lesion characteristics driving inter-hemispheric reorganization of language comprehension and language production in 19 patients (7-32years; eight females) with congenital left-hemispheric brain lesions (periventricular lesions [n=11] and middle cerebral artery infarctions [n=8]) by fMRI...
May 23, 2017: Brain and Language
https://www.readbyqxmd.com/read/28549109/il-18-cleavage-triggers-cardiac-inflammation-and-fibrosis-upon-%C3%AE-adrenergic-insult
#2
Han Xiao, Hao Li, Jing-Jing Wang, Jian-Shu Zhang, Jing Shen, Xiang-Bo An, Cong-Cong Zhang, Ji-Min Wu, Yao Song, Xin-Yu Wang, Hai-Yi Yu, Xiang-Ning Deng, Zi-Jian Li, Ming Xu, Zhi-Zhen Lu, Jie Du, Wei Gao, Ai-Hua Zhang, Yue Feng, You-Yi Zhang
Aims: Rapid over-activation of β-adrenergic receptor (β-AR) upon stress leads to cardiac inflammation, a prevailing factor that underlies heart injury. However, mechanisms by which acute β-AR stimulation induce cardiac inflammation still remain unknown. Here, we set out to identify the crucial role of inflammasome/interleukin (IL)-18 in initiating and maintaining cardiac inflammatory cascades upon β-AR insult. Methods and results: Male C57BL/6 mice were injected with a single dose of β-AR agonist, isoproterenol (ISO, 5 mg/kg body weight) or saline subcutaneously...
May 26, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28548516/relativistic-electron-streaming-instabilities-modulate-proton-beams-accelerated-in-laser-plasma-interactions
#3
S Göde, C Rödel, K Zeil, R Mishra, M Gauthier, F-E Brack, T Kluge, M J MacDonald, J Metzkes, L Obst, M Rehwald, C Ruyer, H-P Schlenvoigt, W Schumaker, P Sommer, T E Cowan, U Schramm, S Glenzer, F Fiuza
We report experimental evidence that multi-MeV protons accelerated in relativistic laser-plasma interactions are modulated by strong filamentary electromagnetic fields. Modulations are observed when a preplasma is developed on the rear side of a μm-scale solid-density hydrogen target. Under such conditions, electromagnetic fields are amplified by the relativistic electron Weibel instability and are maximized at the critical density region of the target. The analysis of the spatial profile of the protons indicates the generation of B>10  MG and E>0...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548482/simultaneous-separation-and-washing-of-non-magnetic-particles-in-an-inertial-ferrofluid-water-co-flow
#4
Qi Chen, Di Li, Jianhan Lin, Mao-Hua Wang, Xiangchun Xuan
Magnetic fluids (e.g., paramagnetic solutions and ferrofluids) have been increasingly used for label-free separation of non-magnetic particles in microfluidic devices. Their biocompatibility, however, becomes a concern in high-throughput or large-volume applications. One way to potentially resolve this issue is re-suspending the particles that are separated in a magnetic fluid immediately into a biocompatible buffer. We demonstrate herein the proof-of-principle of the first integration of negative magnetophoresis and inertial focusing for a simultaneous separation and washing of non-magnetic particles in co-flowing ferrofluid and water streams...
May 26, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28548044/falcon-a-highly-flexible-open-source-software-for-closed-loop-neuroscience
#5
Davide Ciliberti, Fabian Kloosterman
OBJECTIVE: Closed-loop experiments provide unique insights into brain dynamics and function. Here, we demonstrate an open-source software platform that enables high-performance real-time processing of streaming experimental data, suitable for a wide range of closed-loop experiments. APPROACH: We wrote a C++ multi-threaded software (Falcon) in which the user can load and execute an arbitrary processing graph. Each node in the graph is internally mapped to a single thread and nodes communicate with each other through thread-safe buffers...
May 26, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28547680/the-influence-of-attention-on-value-integration
#6
Melina A Kunar, Derrick G Watson, Konstantinos Tsetsos, Nick Chater
People often have to make decisions based on many pieces of information. Previous work has found that people are able to integrate values presented in a rapid serial visual presentation (RSVP) stream to make informed judgements on the overall stream value (Tsetsos et al. Proceedings of the National Academy of Sciences of the United States of America, 109(24), 9659-9664, 2012). It is also well known that attentional mechanisms influence how people process information. However, it is unknown how attentional factors impact value judgements of integrated material...
May 25, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28546030/new-insights-into-health-financing-first-results-of-the-international-data-collection-under-the-system-of-health-accounts-2011-framework
#7
Michael Mueller, David Morgan
International comparisons of health spending and financing are most frequently carried out using datasets of international organisations based on the System of Health Accounts (SHA). This accounting framework has recently been updated and 2016 saw the first international data collection under the new SHA 2011 guidelines. In addition to reaching better comparability of health spending figures and greater country coverage, the updated framework has seen changes in the dimension of health financing leading to important consequences when analysing health financing data...
May 2, 2017: Health Policy
https://www.readbyqxmd.com/read/28545601/startup-of-a-partial-nitritation-anammox-mbbr-and-the-implementation-of-ph-based-aeration-control
#8
Stephanie Klaus, Rick Baumler, Bob Rutherford, Glenn Thesing, Hong Zhao, Charles Bott
  The single-stage deammonification moving bed biofilm reactor (MBBR) is a process for treating high strength nitrogen waste streams. In this process, partial nitritation and anaerobic ammonia oxidation (anammox) occur simultaneously within a biofilm attached to plastic carriers. An existing tank at the James River Treatment Plant (76 ML/d) in Newport News, Virginia was modified to install a sidestream deammonification MBBR process. This was the second sidestream deammonification process in North America and the first MBBR type installation...
June 1, 2017: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28545392/adenylyl-cyclase-mrna-localizes-to-the-posterior-of-polarized-dictyostelium-cells-during-chemotaxis
#9
Satarupa Das, Joshua M Parker, Can Guven, Weiye Wang, Paul W Kriebel, Wolfgang Losert, Daniel R Larson, Carole A Parent
BACKGROUND: In Dictyostelium discoideum, vesicular transport of the adenylyl cyclase A (ACA) to the posterior of polarized cells is essential to relay exogenous 3',5'-cyclic adenosine monophosphate (cAMP) signals during chemotaxis and for the collective migration of cells in head-to-tail arrangements called streams. RESULTS: Using fluorescence in situ hybridization (FISH), we discovered that the ACA mRNA is asymmetrically distributed at the posterior of polarized cells...
May 25, 2017: BMC Cell Biology
https://www.readbyqxmd.com/read/28545359/microbial-enzymatic-degradation-of-biodegradable-plastics
#10
Roohi, Kulsoom Bano, Mohammed Kuddus, Mohd Rehan Zaheer, Qamar Zia, Mohd Farhan Khan, Ghulam Md Ashraf, Gjumrakch Aliev
Background The use of different types of plastics in the world either synthetic or biodegradable has become a part in all sectors of the economy. Infrastructure such as agriculture, building and construction, telecommunication, consumer goods, packaging, health and medical are all high growth areas that ensure a spiralling demand for plastics. Lack of degradability, environmental pollution and closing of landfill sites has led to concern more about plastic waste disposal. Appropriate biodegradation should occur for these water-immiscible polymers since they eventually enter streams which can neither be recycled nor incinerated and also not despoiled with existing physical and chemical means of degradation...
May 23, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28545304/tracing-sources-of-nitrate-using-water-chemistry-land-use-and-nitrogen-isotopes-in-the-ganjiang-river-china
#11
Peng Wang, Junzheng Liu, Shuhua Qi, Shiqin Wang, Xiaoling Chen
In this work, we traced sources of nitrate in the Ganjiang River, a major tributary of Yangtze River, China, by analysing the water chemistry, nitrogen isotopes and land use. Water samples from 20 sites in the main stream and tributaries were collected in the dry and wet seasons. The [Formula: see text] ranged from 0.97 to 8.60 ‰, and was significantly higher in the wet season than in the dry season, and significantly higher in tributaries than in the main stream. In the dry season, [Formula: see text] concentrations and [Formula: see text] were significantly negatively correlated with forest and grassland areas, and positively correlated with paddy field and residential area...
May 25, 2017: Isotopes in Environmental and Health Studies
https://www.readbyqxmd.com/read/28545218/temporal-variability-in-taxonomic-and-trait-compositions-of-invertebrate-assemblages-in-two-climatic-regions-with-contrasting-flow-regimes
#12
Sylvain Dolédec, Jessica Tilbian, Núria Bonada
CONTEXT: Understanding natural temporal changes in Mediterranean rivers with contrasting flow regimes in relation to those of temperate rivers may prove helpful in predicting effects of climate change on aquatic biodiversity. GOAL: We aimed to compare temporal variability in taxonomic and trait compositions of nearly natural rivers in two climatic regions with varying flow regimes to address the effects of future climate changes on aquatic biodiversity in reference conditions...
May 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28543785/phenotypic-and-genotypic-characteristics-of-candida-albicans-isolates-from-bloodstream-and-mucosal-infections
#13
Marina Mandelblat, Michael Frenkel, Darren Abbey, Ronen Ben Ami, Judith Berman, Esther Segal
The interaction of Candida albicans with the host is of a complex nature involving fungal factors and host's response. In this study, we concentrated on the phenotypic expression of virulence attributes and genotypic characteristics of C. albicans isolates from two distinct clinical entities of candidiasis-blood stream and vaginal infections, and the possible role of these factors. Hence, we conducted a comparative in vitro assessment of virulence characteristics, including adhesion to epithelial cells and HaCat cell line, biofilm formation, aspartic proteinases and phospholipase activity of 20 C...
May 22, 2017: Mycoses
https://www.readbyqxmd.com/read/28542918/multisite-external-validation-of-a-risk-prediction-model-for-the-diagnosis-of-blood-stream-infections-in-febrile-pediatric-oncology-patients-without-severe-neutropenia
#14
Adam J Esbenshade, Zhiguo Zhao, Catherine Aftandilian, Raya Saab, Rachel L Wattier, Melissa Beauchemin, Tamara P Miller, Jennifer J Wilkes, Michael J Kelly, Alison Fernbach, Michael Jeng, Cindy L Schwartz, Christopher C Dvorak, Yu Shyr, Karl G M Moons, Maria-Luisa Sulis, Debra L Friedman
BACKGROUND: Pediatric oncology patients are at an increased risk of invasive bacterial infection due to immunosuppression. The risk of such infection in the absence of severe neutropenia (absolute neutrophil count ≥ 500/μL) is not well established and a validated prediction model for blood stream infection (BSI) risk offers clinical usefulness. METHODS: A 6-site retrospective external validation was conducted using a previously published risk prediction model for BSI in febrile pediatric oncology patients without severe neutropenia: the Esbenshade/Vanderbilt (EsVan) model...
May 23, 2017: Cancer
https://www.readbyqxmd.com/read/28542412/low-rates-of-antibiotic-resistance-and-infectious-mortality-in-a-cohort-of-high-risk-hematology-patients-a-single-center-retrospective-analysis-of-blood-stream-infection
#15
Jason R Conn, Elizabeth M Catchpoole, Naomi Runnegar, Sally J Mapp, Kate A Markey
Febrile neutropenia (FN) is a medical emergency and can represent a life-threatening complication for hematology patients treated with intensive chemotherapy regimens. In clinical practice, the diagnostic yield of blood cultures and other investigations which aim to identify a causative organism or site of infection is low. We have retrospectively examined all blood cultures collected in a "real world" cohort of patients receiving chemotherapy for acute leukemia and patients with aggressive lymphoma treated with Hyper-CVAD/MTX-cytarabine, at a single tertiary center over a five-year period...
2017: PloS One
https://www.readbyqxmd.com/read/28542396/using-stochastic-language-models-slm-to-map-lexical-syntactic-and-phonological-information-processing-in-the-brain
#16
Alessandro Lopopolo, Stefan L Frank, Antal van den Bosch, Roel M Willems
Language comprehension involves the simultaneous processing of information at the phonological, syntactic, and lexical level. We track these three distinct streams of information in the brain by using stochastic measures derived from computational language models to detect neural correlates of phoneme, part-of-speech, and word processing in an fMRI experiment. Probabilistic language models have proven to be useful tools for studying how language is processed as a sequence of symbols unfolding in time. Conditional probabilities between sequences of words are at the basis of probabilistic measures such as surprisal and perplexity which have been successfully used as predictors of several behavioural and neural correlates of sentence processing...
2017: PloS One
https://www.readbyqxmd.com/read/28542162/carbapenem-resistant-klebsiella-pneumoniae-in-barbados-driving-change-in-practice-at-the-national-level
#17
Corey Forde, Bryan Stierman, Pilar Ramon-Pardo, Thais Dos Santos, Nalini Singh
INTRODUCTION: Carbapenem-resistant Klebsiella pneumoniae (CRKP) is of growing concern globally. The risk for transmission of antimicrobial resistant organisms across several continents to the Caribbean is a real one given its tourism industry. After a cluster of cases of CRKP were detected, several studies detailed in this report were initiated to better characterize the problem. METHODS: A hospital-wide point prevalence study and active surveillance were performed at Queen Elizabeth Hospital (QEH) in Barbados in 2013 to assess the prevalence of CRKP infection/colonization...
2017: PloS One
https://www.readbyqxmd.com/read/28541208/image-based-models-for-specularity-propagation-in-diminished-reality
#18
Souheil Hadj Said, Mohamed Tamaazousti, Adrien Bartoli
The aim of Diminished Reality (DR) is to remove a target object in a live video stream seamlessly. In our approach, the area of the target object is replaced with new texture that blends with the rest of the image. The result is then propagated to the next frames of the video. One of the important stages of this technique is to update the target region with respect to the illumination change. This is a complex and recurrent problem when the viewpoint changes. We show that the state-of-the-art in DR fails in solving this problem, even under simple scenarios...
May 18, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28541205/features-classification-forest-a-novel-development-that-is-adaptable-to-robust-blind-watermarking-techniques
#19
Chia-Sung Chang, Jau-Ji Shen
A novel watermarking scheme is proposed that could substantially improve current watermarking techniques. This scheme exploits the features of micro images of watermarks to build association rules and embeds the rules into a host image instead of the bit stream of the watermark, which is commonly used in digital watermarking. Next, similar micro images with the same rules are collected or even created from the host image to simulate an extracted watermark. This method, called the Features Classification Forest, can achieve blind extraction and is adaptable to any watermarking scheme using a quantization-based mechanism...
May 19, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28540945/3d-measurement-and-simulation-of-surface-acoustic-wave-driven-fluid-motion-a-comparison
#20
Florian Kiebert, Stefan Wege, Julian Massing, Jörg König, Christian Cierpka, Robert Weser, Hagen Schmidt
The characterisation of the fluid motion induced by the acoustic streaming effect is of paramount interest for novel microfluidic devices based on surface acoustic waves (SAWs), e.g. for a detailed description of the achievable mixing efficiency and thus the design of such devices. Here, we present for the first time a quantitative 3D comparison between experimental measurements and numerical simulations of the acoustic streaming induced fluid flow inside a microchannel originating from a SAW. On the one hand, we performed fully three-dimensional velocity measurements using the astigmatism particle tracking velocimetry...
May 25, 2017: Lab on a Chip
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