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https://www.readbyqxmd.com/read/27932915/icollections-digitising-the-british-and-irish-butterflies-in-the-natural-history-museum-london
#1
Gordon Paterson, Sara Albuquerque, Vladimir Blagoderov, Stephen Brooks, Steve Cafferty, Elisa Cane, Victoria Carter, John Chainey, Robyn Crowther, Lyndsey Douglas, Joanna Durant, Liz Duffell, Adrian Hine, Martin Honey, Blanca Huertas, Theresa Howard, Rob Huxley, Ian Kitching, Sophie Ledger, Caitlin McLaughlin, Geoff Martin, Gerardo Mazzetta, Malcolm Penn, Jasmin Perera, Mike Sadka, Elisabetta Scialabba, Angela Self, Darrell J Siebert, Chris Sleep, Flavia Toloni, Peter Wing
BACKGROUND: The Natural History Museum, London (NHMUK) has embarked on an ambitious programme to digitise its collections . The first phase of this programme has been to undertake a series of pilot projects that will develop the necessary workflows and infrastructure development needed to support mass digitisation of very large scientific collections. This paper presents the results of one of the pilot projects - iCollections. This project digitised all the lepidopteran specimens usually considered as butterflies, 181,545 specimens representing 89 species from the British Isles and Ireland...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27931306/idiopathic-cd4-lymphocytopenia
#2
Joel P Brooks, Gisoo Ghaffari
BACKGROUND: Idiopathic CD4 lymphocytopenia (ICL) is a rare disorder of unknown etiology. Diagnostic criteria include a persistent CD4 T-cell lymphopenia with no underlying primary or secondary immune deficiencies and a CD4 T-cell count of 300 cells/mL or 20% total lymphocyte on multiple occasions. OBJECTIVE: To increase awareness of ICL and to provide a review of the clinical characteristics, diagnosis, and management of this disease process. Presently, many of these patients receive prophylactic treatment similar to other T-cell deficient conditions, most notably patients with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome; however, the same indications may not necessarily apply to this patient population because the T cells are not affected by a virus as in HIV...
November 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27931210/ontological-security-and-connectivity-provided-by-pets-a-study-in-the-self-management-of-the-everyday-lives-of-people-diagnosed-with-a-long-term-mental-health-condition
#3
Helen Brooks, Kelly Rushton, Sandra Walker, Karina Lovell, Anne Rogers
BACKGROUND: Despite evidence that connecting people to relevant wellbeing-related resources brings therapeutic benefit, there is limited understanding, in the context of mental health recovery, of the potential value and contribution of pet ownership to personal support networks for self-management. This study aimed to explore the role of pets in the support and management activities in the personal networks of people with long-term mental health problems. METHODS: Semi-structured interviews centred on 'ego' network mapping were conducted in two locations (in the North West and in the South of England) with 54 participants with a diagnosis of a long-term mental health problem...
December 9, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27931092/the-influence-of-race-and-common-genetic-variations-on-outcomes-after-pediatric-heart-transplantation
#4
D J Green, M M Brooks, G J Burckart, R E Chinnock, C Canter, L J Addonizio, D Bernstein, J K Kirklin, D C Naftel, D M Girnita, A Zeevi, S A Webber
Significant racial disparity remains in the incidence of unfavorable outcomes following heart transplantation. We sought to determine which pediatric post-transplantation outcomes differ by race and whether these can be explained by recipient demographic, clinical, and genetic attributes. Data were collected for 80 black and 450 non-black pediatric recipients transplanted at 1 of 6 centers between 1993 and 2008. Genotyping was performed for 20 candidate genes. Average follow-up was 6.25 years. Unadjusted five-year rates for death (p=0...
December 8, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27928463/renal-progenitors-roles-in-kidney-disease-and-regeneration
#5
REVIEW
Brooke E Chambers, Rebecca A Wingert
Kidney disease is a devastating condition that affects millions of people worldwide, and its prevalence is predicted to significantly increase. The kidney is a complex organ encompassing many diverse cell types organized in a elaborate tissue architecture, making regeneration a challenging feat. In recent years, there has been a surge in the field of stem cell research to develop regenerative therapies for various organ systems. Here, we review some recent progressions in characterizing the role of renal progenitors in development, regeneration, and kidney disease in mammals...
November 26, 2016: World Journal of Stem Cells
https://www.readbyqxmd.com/read/27928031/multi-casting-approach-for-vascular-networks-in-cellularized-hydrogels
#6
Alexander W Justin, Roger A Brooks, Athina E Markaki
Vascularization is essential for living tissue and remains a major challenge in the field of tissue engineering. A lack of a perfusable channel network within a large and densely populated tissue engineered construct leads to necrotic core formation, preventing fabrication of functional tissues and organs. We report a new method for producing a hierarchical, three-dimensional (3D) and perfusable vasculature in a large, cellularized fibrin hydrogel. Bifurcating channels, varying in size from 1 mm to 200-250 µm, are formed using a novel process in which we convert a 3D printed thermoplastic material into a gelatin network template, by way of an intermediate alginate hydrogel...
December 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/27927887/surface-sensitive-microwear-texture-analysis-of-attrition-and-erosion
#7
S Ranjitkar, A Turan, C Mann, G A Gully, M Marsman, S Edwards, J A Kaidonis, C Hall, D Lekkas, P Wetselaar, A H Brook, F Lobbezoo, G C Townsend
Scale-sensitive fractal analysis of high-resolution 3-dimensional surface reconstructions of wear patterns has advanced our knowledge in evolutionary biology, and has opened up opportunities for translatory applications in clinical practice. To elucidate the microwear characteristics of attrition and erosion in worn natural teeth, we scanned 50 extracted human teeth using a confocal profiler at a high optical resolution (X-Y, 0.17 µm; Z < 3 nm). Our hypothesis was that microwear complexity would be greater in erosion and that anisotropy would be greater in attrition...
December 7, 2016: Journal of Dental Research
https://www.readbyqxmd.com/read/27927505/outcomes-of-pelvic-fixation-in-growing-rod-constructs-an-analysis-of-patients-with-a-minimum-of-4-years-of-follow-up
#8
Jaysson T Brooks, Amit Jain, Francisco Sanchez-Perez-Grueso, David L Skaggs, George H Thompson, Behrooz A Akbarnia, Paul D Sponseller
STUDY DESIGN: Retrospective review. OBJECTIVE: To evaluate which distal anchors in growing rod (GR) constructs optimally correct major curve, pelvic obliquity, sagittal alignment, T1-S1 length, thoracic kyphosis, and lumbar lordosis with the fewest complications at 4 or more years' postoperative follow-up. SUMMARY OF BACKGROUND DATA: Pelvic fixation to the ilium and/or sacrum in GR constructs is used to treat patients with early-onset scoliosis...
May 2016: Spine Deformity
https://www.readbyqxmd.com/read/27926880/luminal-iron-levels-govern-intestinal-tumorigenesis-after-apc-loss-in%C3%A2-vivo
#9
Sorina Radulescu, Matthew J Brookes, Pedro Salgueiro, Rachel A Ridgway, Ewan McGhee, Kurt Anderson, Samuel J Ford, Daniel H Stones, Tariq H Iqbal, Chris Tselepis, Owen J Sansom
No abstract text is available yet for this article.
December 6, 2016: Cell Reports
https://www.readbyqxmd.com/read/27925662/clinical-and-pathological-features-of-hair-coat-abnormalities-in-curly-coated-retrievers-from-uk-and-sweden
#10
R Bond, K Varjonen, A Hendricks, Y M Chang, H Brooks Brownlie
OBJECTIVES: To gain information on hair loss amongst curly coated retrievers by questionnaire and to define the clinical and pathological features of hair coat abnormalities in affected dogs in the United Kingdom and Sweden. MATERIALS AND METHODS: Questionnaires were completed by members of the Curly Coated Retriever Clubs. Fourteen dogs (six in the United Kingdom, eight in Sweden) were clinically examined and skin/hair samples collected for microscopy and histopathology...
December 2016: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/27925487/a-novel-safer-conception-counseling-toolkit-for-the-prevention-of-hiv-a-mixed-methods-evaluation-in-kisumu-kenya
#11
Joelle Brown, Betty Njoroge, Eliud Akama, Brooke Breitnauer, Anna Leddy, Lynae Darbes, Richard Omondi, Okeoma Mmeje
Safer conception strategies can prevent HIV transmission between HIV-discordant partners while allowing them to conceive. However, HIV care providers in sub-Saharan Africa report they are not trained in safer conception, and patients are not routinely offered safer conception services. This mixed-methods pilot study evaluated the impact, acceptability, and feasibility of a novel Safer Conception Counseling Toolkit among providers and patients in Kenya. We enrolled 20 HIV-positive women, 10 HIV-discordant couples, and 10 providers from HIV care and treatment clinics...
December 2016: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/27925290/bisphosphonate-withdrawal-effects-on-bone-formation-and-bone-resorption-in-maturing-male-mice
#12
Frank C Ko, Lamya Karim, Daniel J Brooks, Mary L Bouxsein, Marie B Demay
Bisphosphonates are being increasingly used to treat pediatric patients with skeletal disorders. However, the effects of long-term bisphosphonate therapy and cessation of therapy during growth are unclear. Thus, studies were undertaken to determine the effects of alendronate discontinuation following treatment of C57Bl/6 mice during the period of rapid skeletal growth. Compared to vehicle-treated mice, 16 weeks of alendronate treatment starting at 18 days of age resulted in a 3.7 fold increase in trabecular bone in the setting of suppressed bone formation...
December 7, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/27924336/the-single-molecule-electrical-conductance-of-a-rotaxane-hexayne-supramolecular-assembly
#13
David C Milan, Maximilian Krempe, Ali K Ismael, Levon D Movsisyan, Michael Franz, Iain Grace, Richard J Brooke, Walther Schwarzacher, Simon J Higgins, Harry L Anderson, Colin J Lambert, Rik R Tykwinski, Richard J Nichols
Oligoynes are archetypical molecular wires due to their 1-D chain of conjugated carbon atoms and ability to transmit charge over long distances by coherent tunneling. However, the stability of the oligoyne can be an issue. Here we address this problem by two stabilization methods, namely sterically shielding endgroups, and rotaxination to produce an insulated molecular wire. We demonstrate the threading of a hexayne within a macrocycle to form a rotaxane and report measurements of the electrical conductance of this single supramolecular assembly within an STM break junction...
December 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27923965/awareness-of-prostate-cancer-and-screening-modalities-among-long-island-men
#14
James A Leonard, Jenna B Wells, Ethan S Brandler
Despite advances in prostate cancer (PC) treatment and outcomes, it remains one of the most commonly diagnosed cancers and the second leading cause of cancer mortality in men. Furthermore, there exist little data about patient awareness of PC and the frequency of screening. Adult men (470) presenting to the emergency department at a tertiary care center (Stony Brook University) between 2014 and 2015 were surveyed orally for their perceived risk of PC, awareness of PC and screening modalities, and screening history...
December 5, 2016: American Journal of Men's Health
https://www.readbyqxmd.com/read/27923896/reflections-on-the-national-patient-reported-outcome-measures-proms-programme-where-do-we-go-from-here
#15
Derek Kyte, Paul Cockwell, Mauro Lencioni, Magdalena Skrybant, Maria von Hildebrand, Gary Price, Katie Squire, Shena Webb, Olivia Brookes, Hilary Fanning, Tim Jones, Melanie Calvert
No abstract text is available yet for this article.
December 2016: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/27923726/single-stage-soft-tissue-reconstruction-and-orbital-fracture-repair-for-complex-facial-injuries
#16
Peng Sen Wu, Reshvin Matoo, Hong Sun, Li Yuan Song, Don O Kikkawa, Wei Lu
BACKGROUND: Orbital fractures with open periorbital wounds cause significant morbidity. Timing of debridement with fracture repair and soft tissue reconstruction is controversial. This study focuses on the efficacy of early single-stage repair in combined bony and soft tissue injuries. METHODS: Retrospective review. Twenty-three patients with combined open soft tissue wounds and orbital fractures were studied for single-stage orbital reconstruction and periorbital soft tissue repair...
November 11, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27923563/association-between-the-cdhr3-rs6967330-risk-allele-and-chronic-rhinosinusitis
#17
Eugene H Chang, Amanda L Willis, Hilary C McCrary, George T Noutsious, Christopher H Le, Alexander G Chiu, Corrine J Mansfield, Danielle R Reed, Steven G Brooks, Nithin D Adappa, James N Palmer, Noam G Cohen, Debra A Stern, Stefano Guerra, Fernando D Martinez
A retrospective, multi-center study of adults with and without chronic rhinosinusitis (CRS) identifies a significant association between rs6967330 in the viral receptor CDHR3 - known to be associated with wheezing and asthma in children - and the development of CRS.
December 3, 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27923523/polysorbate-80-and-polymyxin-b-inhibit-stenotrophomonas-maltophilia-biofilm
#18
Adam M Malinowski, Bryan M McClarty, Carolyn Robinson, William Spear, Maria Sanchez, Timothy C Sparkes, Joanna S Brooke
Stenotrophomonas maltophilia is an opportunistic multiple-drug-resistant human pathogen that forms biofilms on implanted medical devices. We examined the potential inhibitory activity of polysorbate 80 and polymyxin B against S. maltophilia. A combination of subMIC polymyxin B and polysorbate 80 was the most effective inhibitor of growth and biofilm formation.
November 14, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27922771/giant-cell-myocarditis-a-brief-review
#19
Jin Xu, Erin G Brooks
Giant cell myocarditis (GCM) is a rapidly progressive and frequently fatal disease that mainly affects young to middle-aged previously healthy individuals. Early diagnosis is critical, as recent studies have shown that rapidly instituted cyclosporine-based immunosuppression can reduce inflammation and improve transplant-free survival. Before the 1980s, GCM was mainly a diagnosis made at autopsy. Owing to advancements in diagnostic and therapeutic options, it is now increasingly diagnosed on the basis of endomyocardial biopsies, explanted hearts, or apical wedge sections removed at the time of ventricular assist device placement...
December 2016: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/27922579/srs-22r-scores-in-non-operated-adolescent-idiopathic-scoliosis-patients-with-curves-greater-than-forty-degrees
#20
W Timothy Ward, Nicole A Friel, Tanya S Kenkre, Maria M Brooks, Joanne A Londino, James W Roach
STUDY DESIGN: Case control comparative series OBJECTIVE.: Describe surgical range adolescent idiopathic scoliosis (AIS) patients electing to forgo surgery and compare health related quality of life outcomes to a similar cohort of operated AIS patients by the same single surgeon. SUMMARY OF BACKGROUND DATA: No data have been published either documenting SRS-22r scores of non-operated patients with curves ≥ 40° or comparing these scores to a demographically similar operated cohort...
December 2, 2016: Spine
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