keyword
https://read.qxmd.com/read/38558657/a-peculiar-case-of-isolated-bilateral-tympanic-plate-fractures
#1
Priyanka Bhat, Raman Sharma, J C Passey, Niyati Kumari
Tympanic plate fractures are uncommon injuries and carry the risk of external auditory canal stenosis. These injuries are often associated with fractures of adjacent bones like the mandible, maxilla, and temporal bone. Isolated bilateral tympanic bone fractures have rarely been reported. The most frequently advocated treatment for these injuries is surgical to prevent canal stenosis in the future. The effectiveness of non-operative management has been seldom reported. In the current case report, we present an uncommon injury with isolated bilateral tympanic plate fractures secondary to trauma to the mandible with no associated mandible or condylar fractures that were treated non-operatively...
February 2024: Curēus
https://read.qxmd.com/read/38534368/unique-spatial-transcriptomic-profiling-of-the-murine-femoral-fracture-callus-a-preliminary-report
#2
JOURNAL ARTICLE
Will Jiang, Dennis L Caruana, Jungho Back, Francis Y Lee
Fracture callus formation is a dynamic stage of bone activity and repair with precise, spatially localized gene expression. Metastatic breast cancer impairs fracture healing by disrupting bone homeostasis and imparting an altered genomic profile. Previous sequencing techniques such as single-cell RNA and in situ hybridization are limited by missing spatial context and low throughput, respectively. We present a preliminary approach using the Visium CytAssist spatial transcriptomics platform to provide the first spatially intact characterization of genetic expression changes within an orthopedic model of impaired fracture healing...
March 16, 2024: Cells
https://read.qxmd.com/read/38528064/visualization-of-bone-formation-in-sheep-s-middle-ear-by-using-fluorochrome-sequential-labelling-fsl
#3
JOURNAL ARTICLE
Max Kemper, Anne Kluge, Michael Ney, Thomas Beleites, Ines Zeidler-Rentzsch, Christiane Keil, Thomas Zahnert, Marcus Neudert
One factor for the lacking integration of the middle ear stapes footplate prosthesis or the missing healing of stapes footplate fractures could be the known osteogenic inactivity. In contrast, it was recently demonstrated that titanium prostheses with an applied collagen matrix and immobilised growth factors stimulate osteoblastic activation and differentiation on the stapes footplate. Regarding those findings, the aim of this study was to evaluate the potential of bone regeneration including bone remodeling in the middle ear...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38506383/investigation-of-fatal-traumatic-head-injuries
#4
JOURNAL ARTICLE
Kerem Sehlikoğlu, Abdurrahim Türkoğlu, Turgay Bork, Muhammet Batbaş
BACKGROUND: Traumatic head injuries (THIs) are one of the major causes of death in forensic cases. The aim of this study was to investigate the characteristics of patients with fatal THIs. METHODS: In this study, a total of 311 patients with fatal THIs, who underwent postmortem examinations and/or autopsies, were retrospectively analyzed. Cases were evaluated based on sex, age group, incident origin, cause of the incident, presence of skull fracture, type of fractured bone (if any), fracture localization and pattern, presence and type of intracranial lesion (if any), and cause of death...
March 2024: Turkish Journal of Trauma & Emergency Surgery: TJTES
https://read.qxmd.com/read/38484966/-sandwich-structure-in-reconstruction-of-traumatic-comminuted-anterior-skull-base-fractures-surgical-technique-and-outcomes
#5
JOURNAL ARTICLE
Yu Wang, Jiahai Ding, Xiaoya Huang, Shao Xie
PURPOSE: Comminuted fractures of the anterior skull base can easily cause dural damage, leading to cerebrospinal fluid leakage and retrograde infection. Skull base reconstruction is essential. This study aimed to present a novel and simple technique for repairing skull base defects using a self-made fascia-bone fragments-fascia "sandwich" structure made by fascia, fracture fragments, and sutures. METHOD: From 2018 to 2023, we performed self-made sandwich structures for skull reconstruction in 10 patients with anterior skull base comminuted fractures...
March 12, 2024: World Neurosurgery
https://read.qxmd.com/read/38468677/traumatic-arteriovenous-fistula-of-the-middle-meningeal-artery-treated-with-selective-coil-embolization-a-case-report
#6
Ryo Aiura, Eisuke Hirose, Marina Hirato, Arisa Umesaki, Sadayoshi Nakayama, Tomoyuki Tsumoto
BACKGROUND: Dural arteriovenous fistulas (AVFs) are reportedly induced by trauma. We report a rare case of traumatic AVF with a direct shunt from the middle meningeal artery (MMA) to the middle meningeal vein (MMV) and multiple drainage routes after head trauma. The patient was effectively treated with selective coil embolization alone without liquid embolic material. CASE DESCRIPTION: A 56-year-old woman was admitted to the emergency department with mild disturbance of consciousness caused by a head contusion after alcohol consumption...
2024: Surgical Neurology International
https://read.qxmd.com/read/38455063/temporal-dynamics-of-immune-stromal-cell-interactions-in-fracture-healing
#7
REVIEW
Christina A Capobianco, Kurt D Hankenson, Alexander J Knights
Bone fracture repair is a complex, multi-step process that involves communication between immune and stromal cells to coordinate the repair and regeneration of damaged tissue. In the US, 10% of all bone fractures do not heal properly without intervention, resulting in non-union. Complications from non-union fractures are physically and financially debilitating. We now appreciate the important role that immune cells play in tissue repair, and the necessity of the inflammatory response in initiating healing after skeletal trauma...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38440666/subtotal-petrosectomy-pictorial-review-of-clinical-indications-and-surgical-approach
#8
JOURNAL ARTICLE
Riccardo Nocini, Davide Soloperto, Valerio Arietti, Francesca De Cecco, Gianfranco Fulco, Daniele Monzani, Daniele Marchioni, Luca Sacchetto
Subtotal petrosectomy (STP) is characterized by obliteration of the middle ear and occlusion of the external auditory canal. The advent of the endoscope has allowed a reduction in morbidity for some conditions such as cholesteatoma and other middle ear disorders, but STP still plays an important role. A retrospective review of medical records and videos of patients who had undergone STP was performed. Perioperative data and images were collected from various clinical cases who had undergone subtotal petrosectomy at our tertiary referral university hospital in Verona...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440600/delayed-hearing-recovery-after-transverse-temporal-bone-fracture-with-otic-capsule-violation-case-report-and-literature-review
#9
JOURNAL ARTICLE
Magdalena Ostrowska, Anitta Sisily Joseph, Maciej J Wróbel
We present a patient who suffered a temporal bone fracture (TBF) encompassing the bony labyrinth. Sensorineural hearing loss was confirmed with an unfavorable prognosis for recovery. Thirteen years later, there is regression of the hearing loss.
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38408330/is-gillies-temporal-incision-necessary-to-successfully-reduce-zygomaticomaxillary-fracture-combined-with-orbital-wall-fracture
#10
JOURNAL ARTICLE
Tae Hwan Park
Gillies temporal approach has been widely used to reduce zygoma fractures. Traditionally, it is the preferred method to reduce the isolated zygomatic arch fracture. It can be combined with other approaches, such as subciliary and intraoral incisions for more complex zygomatic fractures, so-called tripod fractures. In this study, the author hypothesized that complex zygomaticomaxillary bone fracture reduction can successfully be achieved without Gillies temporal incision. The author retrospectively analyzed the medical records and 3D facial Computed Tomography (CT) scans of 80 patients who had orbitozygomaticomaxillary fractures that affected >3 sites among the frontozygomatic suture, zygomaticomaxillary buttress, zygomatic arch, and orbital walls from May 2021 to August 2023...
February 26, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38373739/cochlear-facial-dehiscence-the-most-common-cause-of-facial-nerve-stimulation-from-a-cochlear-implant-a-case-control-study
#11
JOURNAL ARTICLE
Marie Bunne, Marte Myhrum, Muneera Iftikhar, Kjell Rasmussen, Benedicte Falkenberg-Jensen
OBJECTIVES: To investigate the prevalence of cochlear-facial dehiscence (CFD) and other radiographical pathologies in ears with facial nerve stimulation (FNS) from a cochlear implant (CI). METHODS: Retrospective case-control study of 27 patients with CI and FNS on either ear (study group) and 27 patients without FNS, matched for age, sex and type of electrode array (control group). Preoperative CT scans of all 108 ears were re-evaluated. Subanalyses included comparisons between the study and control groups and associations between FNS and radiographic pathologies...
February 19, 2024: Cochlear Implants International
https://read.qxmd.com/read/38302094/risk-of-fractures-and-use-of-bisphosphonates-in-adult-patients-with-immune-thrombocytopenia-a-nationwide-population-based-study
#12
JOURNAL ARTICLE
Nikolaj Mannering, Dennis Lund Hansen, Guillaume Moulis, Waleed Ghanima, Anton Pottegård, Henrik Frederiksen
Corticosteroids remain the first-line treatment of immune thrombocytopenia (ITP), but increase the risk of osteoporosis and fractures. Bisphosphonates are used for the treatment of osteoporosis, but their usage among patients with ITP has not been systemically described. We investigated the risk of fractures and the use of bisphosphonates in adult patients with primary (pITP) and secondary ITP (sITP) compared with matched comparators in a nationwide registry-based cohort study. We identified 4030 patients with pITP (median age 60 years [IQR, 40-74]), 550 with sITP (median age 59 years [IQR, 43-74]) and 182 939 age-sex-matched general population comparators...
February 1, 2024: British Journal of Haematology
https://read.qxmd.com/read/38302002/a-prospective-cohort-study-characterising-incidence-of-dural-venous-sinus-thrombosis-in-traumatic-brain-injury-patients-with-skull-fractures
#13
JOURNAL ARTICLE
Ellen McGuckin, Kwok M Ho, Stephen Honeybul, Emma Stuckey, Swithin Song
BACKGROUND: Limited retrospective data suggest that dural venous sinus thrombosis (DVST) in traumatic brain injury (TBI) patients with skull fractures is common and associated with significant morbidity and mortality. Prospective data accurately characterising the incidence of DVST in high-risk TBI patients are sparse but are needed to develop evidence-based TBI management guidelines. METHODS: After obtaining institutional clinical safety and quality unit approval, 36 adult TBI patients with skull fractures admitted to an Australian level III adult intensive care unit (ICU) between April 2022 and January 2023 were prospectively recruited and underwent CT venogram (CTV) or Magnetic resonance venogram (MRV) within 72 hours of injury...
January 30, 2024: World Neurosurgery
https://read.qxmd.com/read/38288029/a-case-of-osteopetrosis-with-orbital-inflammation-secondary-to-maxillary-osteomyelitis
#14
Takafumi Misaki, Fumiko Murao, Kayo Shinomiya, Akihiro Tani, Masayuki Yamada, Yoshinori Mitamura
INTRODUCTION: Osteopetrosis is a rare heritable disorder characterized by increased bone density resulting from osteoclast dysfunction. Major complications include bone fracture, osteomyelitis, anemia, and cranial nerve compression. Optic atrophy can occur due to compression of the optic nerve. Although osteomyelitis of the jaw is a common complication, it rarely occurs in the maxilla. Here, we report a case of a 74-year-old female with osteopetrosis who developed maxillary osteomyelitis, leading to orbital inflammation...
2024: Case Reports in Ophthalmology
https://read.qxmd.com/read/38282240/the-epidemiological-characteristics-of-pediatric-head-injury-in-hangzhou-china-a-retrospective-study-based-on-cranial-ct-examinations
#15
JOURNAL ARTICLE
Haomin Li, Yushuang Ding, Haichun Zhou, Lei Hu, Yuqing Feng, Zhipeng Shen, Hongxi Zhang, Liqi Shu, Linhua Tan
PRIMARY OBJECTIVE: This study aims to create a pediatric head injury database based on cranial CT examinations and explore their epidemiologic characteristics. METHODS: Data related to cranial CT examinations of pediatric head injuries from March 2014 to March 2021 were collected at outpatient and emergency department of a pediatric medical center. The causes of injury, observable post-injury symptoms, and cranial injury findings were extracted with the assistance of natural language processing techniques...
January 28, 2024: Brain Injury
https://read.qxmd.com/read/38270215/improving-hip-fracture-care-a-five-year-review-of-the-early-contributors-to-the-australian-and-new-zealand-hip-fracture-registry
#16
JOURNAL ARTICLE
Morag E Taylor, Niamh Ramsay, Rebecca Mitchell, Catherine McDougall, Ian A Harris, Jamie Hallen, Nicola Ward, Sarah Hurring, Lara A Harvey, Elizabeth Armstrong, Jacqueline C T Close
OBJECTIVE: The aim of this study was to examine temporal trends (2016-2020) in hip fracture care in Australian and New Zealand (ANZ) hospitals that started providing patient-level data to the ANZ Hip Fracture Registry (ANZHFR) on/before 1 January 2016 (early contributors). METHODS: Retrospective cohort study of early contributor hospitals (n = 24) to the ANZHFR. The study cohort included patients aged ≥50 years admitted with a low trauma hip fracture between 1 January 2016 and 31 December 2020 (n = 26,937)...
March 2024: Australasian Journal on Ageing
https://read.qxmd.com/read/38270168/intracochlear-trauma-and-local-ossification-patterns-differ-between-straight-and-precurved-cochlear-implant-electrodes
#17
JOURNAL ARTICLE
Alexander Geerardyn, MengYu Zhu, Nicolas Verhaert, Alicia M Quesnel
HYPOTHESIS: Trauma to the osseous spiral lamina (OSL) or spiral ligament (SL) during cochlear implant (CI) insertion segregates with electrode type and induces localized intracochlear ossification and fibrosis. BACKGROUND: The goal of atraumatic CI insertion is to preserve intracochlear structures, limit reactive intracochlear tissue formation, and preserve residual hearing. Previous qualitative studies hypothesized a localized effect of trauma on intracochlear tissue formation; however, quantitative studies failed to confirm this...
January 25, 2024: Otology & Neurotology
https://read.qxmd.com/read/38238547/risk-for-diagnosis-or-treatment-of-mood-or-anxiety-disorders-in-adults-after-sars-cov-2-infection-2020-2022
#18
JOURNAL ARTICLE
Christina X Wang, Rhea Kohli, Veronica R Olaker, Pauline Terebuh, Rong Xu, David C Kaelber, Pamela B Davis
COVID-19 is associated with increased risks for mood or anxiety disorders, but it remains uncertain how the association evolves over time or which patient groups are most affected. We conducted a retrospective cohort study using a nationwide database of electronic health records to determine the risk of depressive or anxiety disorder diagnoses after SARS-CoV-2 infection by 3-month blocks from January 2020 to April 2022. The study population comprised 822,756 patients (51.8% female; mean age 42.8 years) with COVID-19 and 2,034,353 patients with other respiratory tract infections (RTIs) (53...
January 18, 2024: Molecular Psychiatry
https://read.qxmd.com/read/38238270/comparison-of-fracture-resistance-between-implant-supported-bis-acryl-interim-3-unit-fdps-using-six-different-strengthening-mechanisms-an-in-vitro-study
#19
JOURNAL ARTICLE
Mohammad Rayyan, Mohamed Sayed, Ali Mohammad Hujeiry, Ghada Ayash
AIM: To investigate six different strengthening mechanisms for three-unit implant-supported provisional restorations. MATERIALS AND METHODS: Six techniques of provisional fixed prostheses (PFP) reinforcement were investigated and were assigned to different groups ( n = 10): group (ZP) zirconia powder, group (SK8) silk thread wrapped as a figure-of-8 pattern around middle third of abutment, group (RC8) size 00 retraction cord wrapped as a figure-of-8 pattern around middle third of abutment, group (RF8) Resin impregnated glass fiber ribbon wrapped as a figure-of-8 pattern around abutment, group (KV8) Kevlar 29 cord wrapped as a figure-of-8 pattern around middle third of abutment, group (KV) Kevlar 29 strands incorporated in resin mix...
November 1, 2023: Journal of Contemporary Dental Practice
https://read.qxmd.com/read/38235582/computational-models-of-bone-fracture-healing-and-applications-a-review
#20
REVIEW
Monan Wang, Guodong Jiang, Haoyu Yang, Xin Jin
Fracture healing is a very complex physiological process involving multiple events at different temporal and spatial scales, such as cell migration and tissue differentiation, in which mechanical stimuli and biochemical factors assume key roles. With the continuous improvement of computer technology in recent years, computer models have provided excellent solutions for studying the complex process of bone healing. These models not only provide profound insights into the mechanisms of fracture healing, but also have important implications for clinical treatment strategies...
January 19, 2024: Biomedizinische Technik. Biomedical Engineering
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