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Temporal bone fracture

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https://www.readbyqxmd.com/read/29027868/posttraumatic-complications-in-pediatric-skull-fracture-dural-sinus-thrombosis-arterial-dissection-and-cerebrospinal-fluid-leakage
#1
Adedamola Adepoju, Matthew A Adamo
OBJECTIVE Skull fracture is associated with several intracranial injuries. The object of this study was to determine the rate of fracture associated with venous thrombosis, intracranial arterial dissection (ICAD), and cerebrospinal fluid (CSF) leakage in pediatric patients. Further, the authors aimed to highlight the features of pediatric skull fracture that predict poor neurological outcomes. METHOD In this retrospective study, the authors evaluated the records of 258 pediatric patients who had incurred a traumatic skull fracture in the period from 2009 to 2015...
October 13, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28971515/serum-proteomic-assessment-of-the-progression-of-fracture-healing
#2
Amira I Hussein, Christian Mancini, Kyle E Lybrand, Margaret E Cooke, Heather E Matheny, Brenna L Hogue, Paul Tornetta, Louis C Gerstenfeld
A targeted proteomic analysis of murine serum over a 35-day course of fracture healing was carried out to determine if serum proteomic changes could be used to monitor the biological progression of fracture healing. Transverse, closed femoral fractures where generated and stabilized with intramedullary fixation. A single stranded DNA aptamer-based multiplexed proteomic approach was used to assay 1310 proteins. The transcriptomic profiles for genes matching the 1310 proteins were obtained by microarray analysis of callus mRNA...
October 2, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28929071/an-evaluation-of-the-surgical-trauma-to-intracochlear-structures-after-insertion-of-cochlear-implant-electrode-arrays-a-comparison-by-round-window-and-antero-inferior-cochleostomy-techniques
#3
Kapil Sikka, Arvind Kairo, Chirom Amit Singh, T S Roy, Sanjeev Lalwani, Rakesh Kumar, Alok Thakar, Suresh C Sharma
To evaluate the extent of intracochlear damage by histologic assessment of cadaveric temporal bones after insertion of cochlear implants by: round window approach and cochleostomy approach. Cochlear implantation was performed by transmastoid facial recess approach in 10 human cadaveric temporal bones. In 5 temporal bones, electrode insertion was acheieved by round window approach and in the remaining 5 bones, by cochleostomy approach. The bones were fixed, decalcified, sectioned and studied histologically. Grading of insertion trauma was assessed...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28910363/impaired-bone-formation-in-ovariectomized-mice-reduces-implant-integration-as-indicated-by-longitudinal-in-vivo-micro-computed-tomography
#4
Zihui Li, Gisela Kuhn, Michael Schirmer, Ralph Müller, Davide Ruffoni
Although osteoporotic bone, with low bone mass and deteriorated bone architecture, provides a less favorable mechanical environment than healthy bone for implant fixation, there is no general agreement on the impact of osteoporosis on peri-implant bone (re)modeling, which is ultimately responsible for the long term stability of the bone-implant system. Here, we inserted an implant in a mouse model mimicking estrogen deficiency-induced bone loss and we monitored with longitudinal in vivo micro-computed tomography the spatio-temporal changes in bone (re)modeling and architecture, considering the separate contributions of trabecular, endocortical and periosteal surfaces...
2017: PloS One
https://www.readbyqxmd.com/read/28860404/the-changing-face-of-fractures-of-the-hip-in-northern-ireland-a-15-year-review
#5
A Tucker, K J Donnelly, S McDonald, J Craig, A P Foster, J D Acton
AIMS: We reviewed all patients who sustained a fracture of the hip and were treated in Northern Ireland over a period of 15 years to identify trends in incidence, the demographics of the patients, the rates of mortality, the configuration of the fracture and the choice of implant. PATIENTS AND METHODS: Since 01 January 2001 data about every fracture of the hip sustained in an adult have been collected centrally in Northern Ireland. All adults with such a fracture between 2000 and 2015 were included in the study...
September 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28713653/frail-phenotype-might-herald-bone-health-worsening-among-end-stage-renal-disease-patients
#6
Chia-Ter Chao, Jenq-Wen Huang, Ding-Cheng Chan
BACKGROUND: Frailty exhibits a high prevalence in end-stage renal disease (ESRD) patients and is associated with adverse health-related outcomes, including falls and fractures. Available studies do not address whether frailty is associated with temporal changes in BMD. We evaluated this issue by analyzing the follow-up dual energy X-ray absorptiometry (DXA) results in an ESRD cohort. METHODS: In 2015, we enrolled forty-three ESRD patients, divided into frail, pre-frail, and robust ones based on a validated simple FRAIL scale, all receiving DXA at baseline...
2017: PeerJ
https://www.readbyqxmd.com/read/28697349/styloid-process-fracture-associated-with-maxillofacial-trauma-incidence-distribution-and-management
#7
Pushpakant Tiwary, Nandakishore Sahoo, Ankur Thakral, Udayan Ranjan
PURPOSE: Fracture of the styloid process of the temporal bone has been infrequently reported. The present study evaluated the incidence, causes, distribution, and management of styloid process fracture in association with other maxillofacial fractures. MATERIALS AND METHODS: A prospective evaluation of patients with maxillofacial trauma over a period of 1 year was carried out and patients' characteristics, mode and distribution of injury, and length of styloid process were recorded...
October 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28693327/in-situ-examination-of-osteoblast-biomineralization-on-sulfonated-polystyrene-modified-substrates-using-fourier-transform-infrared-microspectroscopy
#8
Yizhi Meng, Meghan E Faillace, Kathryn Dorst, Samantha J Palmaccio, Lisa M Miller, Yi-Xian Qin
Osteoporosis is a skeletal disorder that is characterized by the loss of bone mineral density (BMD) resulting in increased risk of fracture. However, it has been shown that BMD is not the only indicator of fracture risk, as the strength of bone depends on a number of factors, including bone mass, architecture and material properties. Physiological mineral deposition requires the formation of a properly developed extracellular matrix (ECM), which recruits calcium and phosphate ions into the synthesis of apatite crystals...
July 10, 2017: Biointerphases
https://www.readbyqxmd.com/read/28684072/surgery-first-approach-in-orthognathic-surgery-psychological-and-biological-aspects-a-prospective-cohort-study
#9
Sebastian Zingler, Emad Hakim, Dominic Finke, Monika Brunner, Daniel Saure, Jürgen Hoffmann, Christopher J Lux, Ralf Erber, Robin Seeberger
INTRODUCTION: The aim of this pilot study was to investigate psychological and biological changes after application of a surgery-first orthognathic treatment approach. METHODS: A prospective cohort study of 9 patients (6 women and 3 men; mean age 26.7 years) suffering from skeletal Class II and III deformities was conducted. Skeletal changes from pre-to post-treatment were analyzed based on data acquired by use of cone-beam computed tomography (CBCT). Psychological changes were analyzed using the orthognathic quality of life (OQLQ) questionnaire, Sense of Coherence 29-item scale (SOC-29) and longitudinal day-to-day questionnaire...
August 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28676439/the-effect-of-stress-fracture-interventions-in-a-single-elite-infantry-training-unit-1983-2015
#10
Charles Milgrom, Aharon S Finestone
Stress fractures can be seen as an undesired byproduct of demanding physical training. The threshold value of stress that places an individual bone at high risk for stress fracture has not been identified. In a prospective study of stress fractures in 1983, a 31% incidence was found during demanding Israeli infantry basic training by bone scan criteria. Within a subgroup of these recruits, an elite infantry unit was found to have a 40% incidence. Since then and until 2015, eight additional induction companies of the same elite infantry unit were prospectively monitored for stress fractures during their basic training...
July 1, 2017: Bone
https://www.readbyqxmd.com/read/28647583/the-temporal-expression-of-adipokines-during-spinal-fusion
#11
Sohrab Virk, Alicia L Bertone, Hayam Hamaz Hussein, Jeffrey M Toth, Mari Kaido, Safdar Khan
BACKGROUND CONTEXT: Adipokines are secreted by white adipose tissue and have been associated with fracture healing. Our goal was to report the temporal expression of adipokines during spinal fusion in an established rabbit model. PURPOSE: Our goal was to report the temporal expression of adipokines during spinal fusion in an established rabbit model. STUDY DESIGN: Laboratory animal model METHODS: New Zealand white rabbits were assigned to either sham surgery (n=2), unilateral posterior spinal fusion (n=14) or bilateral posterior spinal fusion (n=14)...
June 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28639740/declining-rates-of-hip-fracture-in-end-stage-renal-disease-analysis-from-the-2003-2011-nationwide-inpatient-sample
#12
Sun Moon Kim, Sai Liu, Jin Long, Maria E Montez-Rath, Mary B Leonard, Glenn M Chertow
The incidence of hip fracture in patients with end-stage renal disease (ESRD) is considerably higher than that in the general age- and sex-matched population. Although medical therapy for chronic kidney disease mineral bone disorder (CKD-MBD) has changed considerably over the last decade, rates of hip fracture in the entire ESRD population have not been well-characterized. Herein, we evaluated temporal trends in rates of hip fracture, in-hospital mortality, and costs of associated hospital stay in ESRD. We identified hospitalizations for hip fracture from 2003 to 2011 using the Nationwide Inpatient Sample, a representative national database inclusive of all ages and payers...
June 22, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28631687/-acquired-atresia-and-stenosis-of-the-external-acoustic-meatus
#13
REVIEW
D S Kondratchikov, Kh M Diab, V S Korvyakov, L I Terekhina
Acquired atresia of the external acoustic meatus is a rare pathological condition characterized by obliteration of the medial part of the external acoustic canal by a soft fibrous plug. The present article presents an overview of a series of cases of acquired atresia and stenosis of the external acoustic meatus with the description of etiology, pathogenesis, and methods for the treatment of this condition. In the majority of the cases, atresia develops at the final stage of granulation external otitis with or without an accompanying dermatological pathology...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28623826/mechanical-characterization-via-nanoindentation-of-the-woven-bone-developed-during-bone-transport
#14
J Mora-Macías, A Pajares, P Miranda, J Domínguez, E Reina-Romo
Nanoindentation has been used successfully in the determination of the mechanical properties of bone. Its application in fracture healing provides information on the evolution of material properties of the woven bone during regeneration process. However, this technique has not been applied in assessing the mechanical properties of woven bone during distraction osteogenesis. Therefore, the aim of this work is to evaluate the spatial and temporal variations of the elastic modulus of the woven bone generated during the bone transport process...
October 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28551022/the-relationship-between-post-traumatic-ossicular-injuries-and-conductive-hearing-loss-a-3d-ct-study
#15
Olivier Maillot, Arnaud Attyé, Claire Boutet, Kamel Boubagra, Romain Perolat, Marion Zanolla, Sylvie Grand, Sébastien Schmerber, Alexandre Krainik
PURPOSE: After a trauma, the conductive ossicular chain may be disrupted by ossicular luxation or fracture. Recent developments in 3D-CT allow a better understanding of ossicular injuries. In this retrospective study, we compared patients with post-traumatic conductive hearing loss (CHL) with those referred without CHL to evaluate the relationship between ossicular injuries and CHL. We also assessed the added value of 3D reconstructions on 2D-CT scan to detect ossicular lesions in patients surgically managed...
May 24, 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28523266/stimulating-fracture-healing-in-ischemic-environments-does-oxygen-direct-stem-cell-fate-during-fracture-healing
#16
REVIEW
Katherine R Miclau, Sloane A Brazina, Chelsea S Bahney, Kurt D Hankenson, Thomas K Hunt, Ralph S Marcucio, Theodore Miclau
Bone fractures represent an enormous societal and economic burden as one of the most prevalent causes of disability worldwide. Each year, nearly 15 million people are affected by fractures in the United States alone. Data indicate that the blood supply is critical for fracture healing; as data indicate that concomitant bone and vascular injury are major risk factors for non-union. However, the various role(s) that the vasculature plays remains speculative. Fracture stabilization dictates stem cell fate choices during repair...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28472361/energy-metabolism-of-the-osteoblast-implications-for-osteoporosis
#17
Wen-Chih Lee, Anyonya R Guntur, Fanxin Long, Clifford J Rosen
Osteoblasts, the bone-forming cells of the remodeling unit, are essential for growth and maintenance of the skeleton. Clinical disorders of substrate availability (e.g., diabetes mellitus, anorexia nervosa, and aging) cause osteoblast dysfunction, ultimately leading to skeletal fragility and osteoporotic fractures. Conversely, anabolic treatments for osteoporosis enhance the work of the osteoblast by altering osteoblast metabolism. Emerging evidence supports glycolysis as the major metabolic pathway to meet ATP demand during osteoblast differentiation...
June 1, 2017: Endocrine Reviews
https://www.readbyqxmd.com/read/28448419/venous-sinus-thrombosis-in-blunt-trauma-incidence-and-risk-factors
#18
Shira E Slasky, Yayone Rivaud, Matthew Suberlak, Oluwole Tairu, Adam D Fox, Pamela Ohman-Strickland, Esther Bilinisky
PURPOSE: The aim of our study was to determine the incidence and risk factors of dural venous sinus thrombosis and epidural hemorrhage in the setting of a blunt trauma causing a calvarial fracture crossing a dural venous sinus. METHODS: A retrospective review of 472 blunt trauma patients with calvarial fracture crossing a dural venous sinus was performed. Two hundred ten patients who underwent computed tomography venography were identified and evaluated for the presence of dural venous sinus thrombosis and/or epidural hemorrhage...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28447646/a-130-000-year-old-archaeological-site-in-southern-california-usa
#19
Steven R Holen, Thomas A Deméré, Daniel C Fisher, Richard Fullagar, James B Paces, George T Jefferson, Jared M Beeton, Richard A Cerutti, Adam N Rountrey, Lawrence Vescera, Kathleen A Holen
The earliest dispersal of humans into North America is a contentious subject, and proposed early sites are required to meet the following criteria for acceptance: (1) archaeological evidence is found in a clearly defined and undisturbed geologic context; (2) age is determined by reliable radiometric dating; (3) multiple lines of evidence from interdisciplinary studies provide consistent results; and (4) unquestionable artefacts are found in primary context. Here we describe the Cerutti Mastodon (CM) site, an archaeological site from the early late Pleistocene epoch, where in situ hammerstones and stone anvils occur in spatio-temporal association with fragmentary remains of a single mastodon (Mammut americanum)...
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28414141/temporal-role-of-macrophages-in-cancellous-bone-healing
#20
Olof Helge Sandberg, Love Tätting, Magnus Erik Bernhardsson, Per Aspenberg
Macrophages are important phagocytosing and cytokine producing cells with effects on fracture healing. We used clodronate-containing liposomes to reduce the number of macrophages, in order to study their role in the early phases of cancellous bone healing. Holes were drilled bilaterally into the cancellous bone of the proximal metaphysis of the tibia of 60 mice. A screw was inserted in the hole in the right tibia. The day of surgery was day 0. Clodronate-containing liposomes were injected intraperitoneally as a single injection either day -4 or -1 (before surgery) or day 1 or 3 (after surgery)...
April 14, 2017: Bone
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