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https://www.readbyqxmd.com/read/28535318/allopathic-and-osteopathic-medicine-unify-gme-accreditation-a-historic-convergence
#1
Abdul-Kareem H Ahmed, Peter F Schnatz, Eli Y Adashi
In 1968, the American Medical Association resolved to accept qualified graduates of osteopathic medical schools into its accredited Graduate Medical Education (GME) programs. An equally momentous decision was arrived at in 2014 when the Accreditation Council for Graduate Medical Education (ACGME), the American Osteopathic Association (AOA), and the American Association of Colleges of Osteopathic Medicine (AACOM) resolved to institute a single unified GME accreditation system by July 1, 2020. As envisioned, the unified accreditation system will all but assure system-wide consistency of purpose and practice in anticipation of the Next Accreditation System (NAS) of the ACGME...
May 2017: Family Medicine
https://www.readbyqxmd.com/read/28534859/workplace-hazards-faced-by-nursing-assistants-in-the-united-states-a-focused-literature-review
#2
REVIEW
AnnMarie Lee Walton, Bonnie Rogers
Nursing assistants (NAs) make up a large share of the healthcare provider workforce and their numbers are expected to grow. NAs are predominantly women who earn a low wage and report financial, work, and family demands. Working as a NA is hazardous; this manuscript specifically examines the biological/infectious, chemical, enviromechanical, physical and psychosocial hazards that appear in the literature to date. A focused search strategy was used to review literature about hazards that fell into each of the five aforementioned domains...
May 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28527793/prevalence-of-non-aureus-staphylococcus-species-causing-intramammary-infections-in-canadian-dairy-herds
#3
Larissa A Z Condas, Jeroen De Buck, Diego B Nobrega, Domonique A Carson, Sohail Naushad, Sarne De Vliegher, Ruth N Zadoks, John R Middleton, Simon Dufour, John P Kastelic, Herman W Barkema
Non-aureus staphylococci (NAS), the microorganisms most frequently isolated from bovine milk worldwide, are a heterogeneous group of numerous species. To establish their importance as a group, the distribution of individual species needs to be determined. In the present study, NAS intramammary infection (IMI) was defined as a milk sample containing ≥1,000 cfu/mL in pure or mixed culture that was obtained from a cohort of cows assembled by the Canadian Bovine Mastitis Research Network. Overall, 6,213 (6.3%) of 98,233 quarter-milk samples from 5,149 cows and 20,305 udder quarters were associated with an NAS IMI...
May 17, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28527047/dietary-ascorbic-acid-reduced-micronucleus-and-nuclear-abnormalities-in-clarias-gariepinus-burchell-1822-exposed-to-hospital-effluent
#4
Chibuisi G Alimba, Raphael D Ajiboye, Olakunle S Fagbenro
Hospital effluents contain myriad of mutagens and genotoxins capable of increasing DNA damage in aquatic biota. African mudfish, Clarias gariepinus, are exposed to genotoxins when cultured in swamps and derelict water bodies often contaminated by effluents. Moreover, its DNA is susceptible to xenobiotic-induced lesions since it lacks L-gulonolactone oxidase and hence cannot synthesize L-ascorbic acid. This study investigated 96-h acute toxicity and protective effects of dietary ascorbic acid (AA) against micronucleus (MN) and abnormal nuclear (NAs) formation in C...
May 19, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28520197/integrated-uncertainty-analysis-for-ambient-pollutant-health-risk-assessment-a-case-study-of-ozone-mortality-risk
#5
Anne E Smith, Garrett Glasgow
The U.S. Environmental Protection Agency (EPA) uses health risk assessment to help inform its decisions in setting national ambient air quality standards (NAAQS). EPA's standard approach is to make epidemiologically-based risk estimates based on a single statistical model selected from the scientific literature, called the "core" model. The uncertainty presented for "core" risk estimates reflects only the statistical uncertainty associated with that one model's concentration-response function parameter estimate(s)...
May 18, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28519244/neonatal-abstinence-syndrome-update-on-diagnostic-and-therapeutic-strategies
#6
Genny Raffaeli, Giacomo Cavallaro, K Karel Allegaert, Enno Diederik Wildschut, Monica Fumagalli, Massimo Agosti, Dick Tibboel, Fabio Mosca
Substance use among pregnant women is a major public health issue. Both prescription opioid use and illicit opioid abuse have increased dramatically in recent years. Prolonged in utero drug exposure may result in neonatal abstinence syndrome (NAS), an acute multisystemic clinical entity that occurs in the first days of life. This syndrome is caused by abrupt discontinuation of fetal exposure to licit or illicit drugs chronically consumed by the mother during pregnancy and transmitted to the fetus through the placenta...
May 18, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28513768/microbiological-testing-of-devices-used-in-maintaining-peripheral-venous-catheters
#7
Fernanda de Paula Rossini, Denise de Andrade, Lissandra Chaves de Sousa Santos, Adriano Menis Ferreira, Caroline Tieppo, Evandro Watanabe
Objective: to evaluate the use of peripheral venous catheters based on microbiological analysis of devices (dressing and three-way stopcocks) and thus contribute to the prevention and infection control. Methods: this was a prospective study of microbiological analysis of 30 three-way stopcocks (external surfaces and lumens) and 30 dressing used in maintaining the peripheral venous catheters of hospitalized adult patients. Results: all external surfaces, 40% of lumens, and 86...
May 15, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28513767/capnography-as-a-tool-to-detect-metabolic-changes-in-patients-cared-for-in-the-emergency-setting
#8
Francisco José Cereceda-Sánchez, Jesús Molina-Mula
Objective: to evaluate the usefulness of capnography for the detection of metabolic changes in spontaneous breathing patients, in the emergency and intensive care settings. Methods: in-depth and structured bibliographical search in the databases EBSCOhost, Virtual Health Library, PubMed, Cochrane Library, among others, identifying studies that assessed the relationship between capnography values and the variables involved in blood acid-base balance. Results: 19 studies were found, two were reviews and 17 were observational studies...
May 15, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28513764/vulnerability-to-the-transmission-of-human-visceral-leishmaniasis-in-a-brazilian-urban-area
#9
Celina Roma Sánchez de Toledo, Andréa Sobral de Almeida, Sergio Augusto de Miranda Chaves, Paulo Chagastelles Sabroza, Luciano Medeiros Toledo, Jefferson Pereira Caldas
OBJECTIVE: To analyze the determinants for the occurrence of human visceral leishmaniasis linked to the conditions of vulnerability. METHODS: This is an ecological study, whose spatial analysis unit was the Territorial Analysis Unit in Araguaína, State of Tocantins, Brazil, from 2007 to 2012. We have carried out an analysis of the sociodemographic and urban infrastructure situation of the municipality. Normalized primary indicators were calculated and used to construct the indicators of vulnerability of the social structure, household structure, and urban infrastructure...
May 15, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28513761/socioeconomic-determinants-of-access-to-health-services-among-older-adults-a-systematic-review
#10
Ana Paula Santana Coelho Almeida, Bruno Pereira Nunes, Suele Manjourany Silva Duro, Luiz Augusto Facchini
OBJECTIVE: The objective of this study was to analyze the association between the socioeconomic characteristics and the access to or use of health services among older adults. METHODS: This is a systematic review of the literature. The search has been carried out in the databases PubMed, LILACS and Web of Science, without restriction of dates and languages; however we have included only articles published in Portuguese, English, and Spanish. The inclusion criteria were: observational design, socioeconomic factors as variables of interest in the analysis of the access to or use of health services among older adults, representative sample of the target population, adjustment for confounding factors, and no selection bias...
May 15, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28513534/unraveling-prion-protein-interactions-with-aptamers-and-other-prp-binding-nucleic-acids
#11
REVIEW
Bruno Macedo, Yraima Cordeiro
Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative disorders that affect humans and other mammals. The etiologic agents common to these diseases are misfolded conformations of the prion protein (PrP). The molecular mechanisms that trigger the structural conversion of the normal cellular PrP (PrP(C)) into the pathogenic conformer (PrP(Sc)) are still poorly understood. It is proposed that a molecular cofactor would act as a catalyst, lowering the activation energy of the conversion process, therefore favoring the transition of PrP(C) to PrP(Sc)...
May 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28513156/quantum-chemical-investigation-on-photochemical-reactions-of-nonanoic-acids-at-air-water-interface
#12
Pin Xiao, Qian Wang, Wei-Hai Fang, Ganglong Cui
Photoinduced chemical reactions of organic compounds at the marine boundary layer have recently attracted significant experimental attention because this kind of photoreactions have been proposed to have substantial impact on local new particle formation (NPF) and their photoproducts could be as a source of secondary organic aerosols (SOA). In this work, we have employed first-principles density functional theory (DFT) method combined with cluster models to systematically explore photochemical reaction pathways of nonanoic acids (NAs) to form volatile saturated and unsaturated C9 and C8 aldehydes at air-water interfaces...
May 17, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28503691/a-rapidly-prototyped-microfluidic-device-for-size-based-nucleic-acid-fractionation-using-isotachophoresis
#13
C Eid, S S Branda, R J Meagher
We present a novel microfluidic device for size-based nucleic acid (NA) fractionation using isotachophoresis (ITP) and an ionic spacer. Our rapid-prototyped laser-cut plastic device has easily modifiable channel dimensions, can process up to 10 μL of sample, and contains an in-line extraction reservoir for minimally-disruptive manual collection of size-fractionated NAs. We designed custom buffering reservoirs using 1 mL pipette tips to provide high buffering capacity and prevent bubbles from entering the microfluidic channels...
May 15, 2017: Analyst
https://www.readbyqxmd.com/read/28503198/dynamics-of-two-methanogenic-microbiomes-incubated-in-polycyclic-aromatic-hydrocarbons-naphthenic-acids-and-oil-field-produced-water
#14
Bonahis J Oko, Yu Tao, David C Stuckey
BACKGROUND: Oil field produced water (OFPW) is widely produced in large volumes around the world. Transforming the organic matter in OFPW into bioenergy, such as biomethane, is one promising way to sustainability. However, OFPW is difficult to biologically degrade because it contains complex compounds such as naphthenic acids (NAs), or polycyclic aromatic hydrocarbons (PAHs). Although active microbial communities have been found in many oil reservoirs, little is known about how an exotic microbiome, e...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28500694/trends-of-neonatal-abstinence-syndrome-epidemic-and-maternal-risk-factors-in-florida
#15
Xi Wang, Yanmin Zhu, Chintan V Dave, Adel A Alrwisan, Stacy A Voils, Almut G Winterstein
OBJECTIVE: This study aimed to examine secular trends of (i) maternal prescription opioid use in late pregnancy, (ii) neonatal abstinence syndrome (NAS) stratified by late maternal prescription opioid use, and (iii) maternal risk factors among NAS deliveries. METHODS: Women with a live birth who were enrolled 90 days before and 30 days after delivery in Florida Medicaid Analytic Extract billing records linked to birth certificates from 2000 to 2010 were identified for the study...
May 13, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28500681/comparison-of-time-to-first-dose-of-oral-morphine-in-the-treatment-of-neonatal-abstinence-syndrome
#16
Sarah T Mitchell, Tracy J Costello, Kara M Nedderman
OBJECTIVE: To compare time to first dose of oral morphine used in the treatment of neonatal abstinence syndrome (NAS) in a neonatal intensive care unit (NICU) versus a special care nursery (SCN) setting. METHODS: A retrospective chart review was completed of patient data from two community hospitals in a single health network. Infants born at either facility between January 2013 and August 2015 were eligible for inclusion in the study if treated for NAS with a course of oral morphine...
May 13, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28500629/early-prediction-tool-to-identify-the-need-for-pharmacotherapy-in-infants-at-risk-of-neonatal-abstinence-syndrome
#17
Barbara T Isemann, Elaina C Stoeckle, Afshin A Taleghani, Eric W Mueller
OBJECTIVE: To develop a tool to predict the need for pharmacologic treatment of neonatal abstinence syndrome (NAS) within 36 hours from birth in infants at risk for opioid withdrawal. STUDY DESIGN: Retrospective study of infants born at 34 weeks or later gestation with in utero exposure to opioids during two time periods from January 2013 through October 2016. Period 1 was used to develop a predictive tool for validation during Period 2. Birth weight, gestational age, four categories of opioid exposure, and individual scores for 21 withdrawal symptoms from the Modified Finnegan Score at 36 hours of life were recorded...
May 13, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28496379/self-organization-of-nucleic-acids-in-lipid-constructs
#18
Minjee Kang, Hojun Kim, Cecilia Leal
Lipids and nucleic acids (NAs) can hierarchically self-organize into a variety of nanostructures of increasingly complex geometries such as the 1D lamellar, 2D hexagonal, and 3D bicontinuous cubic phases. The diversity and complexity of those lipid-NA assemblies are interesting from a fundamental perspective as well as being relevant to the performance in gene delivery and gene silencing applications. The finding that not only the chemical make of the lipid-NA constructs, but their actual supramolecular organization, affects their gene transfection and silencing efficiencies has inspired physicists, chemists, and engineers to this field of research...
December 2016: Current Opinion in Colloid & Interface Science
https://www.readbyqxmd.com/read/28495579/a-new-chemotherapy-agent-free-theranostic-system-composed-of-graphene-oxide-nano-complex-and-aptamers-for-treatment-of-cancer-cells
#19
Amirhossein Bahreyni, Rezvan Yazdian-Robati, Shirin Hashemitabar, Mohammad Ramezani, Pouria Ramezani, Khalil Abnous, Seyed Mohammad Taghdisi
The common cancer treatment strategies like chemotherapy and radiotherapy are nonspecific and can trigger severe side effects by damaging normal cells. So, targeted cancer therapies, such as apoptosis induction, have attracted great attention in recent years. In this project, two nano-complexes, MUC1 aptamer-NAS-24 aptamer-Graphene oxide (GO) and MUC1 aptamer-Cytochrome C aptamer-GO, were designed to induce cell programmed death in MDA-MB-231 and MCF-7 cells (breast cancer cell lines) and to verify the level of apoptosis in both cell lines...
May 8, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28493708/discrimination-of-diverse-coherences-allows-identification-of-electronic-transitions-of-a-molecular-nanoring
#20
Vytautas Butkus, Jan Alster, Eglė Bašinskaitė, Ramu Nas Augulis, Patrik Neuhaus, Leonas Valkunas, Harry L Anderson, Darius Abramavicius, Donatas Zigmantas
The role of quantum coherence in photochemical functions of molecular systems such as photosynthetic complexes is a broadly debated topic. Coexistence and intermixing of electronic and vibrational coherences has been proposed to be responsible for the observed long-lived coherences and high energy transfer efficiency. However, clear experimental evidence of coherences with different origins operating at the same time has been elusive. In this work, multidimensional spectra obtained from a six-porphyrin nanoring system are analyzed in detail with support from theoretical modeling...
May 11, 2017: Journal of Physical Chemistry Letters
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