Read by QxMD icon Read


K Szajna, M Kratzer, D Wrana, C Mennucci, B R Jany, F Buatier de Mongeot, C Teichert, F Krok
We have investigated the growth and stability of molecular ultra-thin films, consisting of rod-like semiconducting para-hexaphenyl (6P) molecules vapor deposited on ion beam modified TiO2(110) surfaces. The ion bombarded TiO2(110) surfaces served as growth templates exhibiting nm-scale anisotropic ripple patterns with controllable parameters, like ripple depth and length. In turn, by varying the ripple depth one can tailor the average local slope angle and the local step density/terrace width of the stepped surface...
October 14, 2016: Journal of Chemical Physics
David L Horn, Jong Ho Won, Jay T Rubinstein, Lynne A Werner
OBJECTIVES: Spectral resolution is a correlate of open-set speech understanding in postlingually deaf adults and prelingually deaf children who use cochlear implants (CIs). To apply measures of spectral resolution to assess device efficacy in younger CI users, it is necessary to understand how spectral resolution develops in normal-hearing children. In this study, spectral ripple discrimination (SRD) was used to measure listeners' sensitivity to a shift in phase of the spectral envelope of a broadband noise...
October 20, 2016: Ear and Hearing
Olena Bukalo, Philip R Lee, R Douglas Fields
Action-potential-induced LTD (AP-LTD) is a form of synaptic plasticity that reduces synaptic strength in CA1 hippocampal neurons firing antidromically during sharp-wave ripples. This firing occurs during slow-wave sleep and quiet moments of wakefulness, which are periods of offline replay of neural sequences learned during encoding sensory information. Here we report that rapid and persistent down-regulation of different mRNA transcripts of the BDNF gene accompanies AP-LTD, and that AP-LTD is abolished in mice with the BDNF gene knocked out in CA1 hippocampal neurons...
October 16, 2016: Neuroscience Letters
Krisztián A Kovács, Joseph O'Neill, Philipp Schoenenberger, Markku Penttonen, Damaris K Ranguel Guerrero, Jozsef Csicsvari
During hippocampal sharp wave/ripple (SWR) events, previously occurring, sensory input-driven neuronal firing patterns are replayed. Such replay is thought to be important for plasticity-related processes and consolidation of memory traces. It has previously been shown that the electrical stimulation-induced disruption of SWR events interferes with learning in rodents in different experimental paradigms. On the other hand, the cognitive map theory posits that the plastic changes of the firing of hippocampal place cells constitute the electrophysiological counterpart of the spatial learning, observable at the behavioral level...
2016: PloS One
Hélène Roche
No abstract text is available yet for this article.
October 19, 2016: Nature
Joke A Debruyne, Tom Francart, A Miranda L Janssen, Kim Douma, Jan P L Brokx
OBJECTIVE: This study investigated the hypotheses that (1) prelingually deafened CI users do not have perfect electrode discrimination ability and (2) the deactivation of non-discriminable electrodes can improve auditory performance. DESIGN: Electrode discrimination difference limens were determined for all electrodes of the array. The subjects' basic map was subsequently compared to an experimental map, which contained only discriminable electrodes, with respect to speech understanding in quiet and in noise, listening effort, spectral ripple discrimination and subjective appreciation...
October 19, 2016: International Journal of Audiology
Laura K Holden, Jill B Firszt, Ruth M Reeder, Rosalie M Uchanski, Noël Y Dwyer, Timothy A Holden
OBJECTIVE: To identify primary biographic and audiologic factors contributing to cochlear implant (CI) performance variability in quiet and noise by controlling electrode array type and electrode position within the cochlea. BACKGROUND: Although CI outcomes have improved over time, considerable outcome variability still exists. Biographic, audiologic, and device-related factors have been shown to influence performance. Examining CI recipients with consistent array type and electrode position may allow focused investigation into outcome variability resulting from biographic and audiologic factors...
October 12, 2016: Otology & Neurotology
Nicolas Fraize, Julien Carponcy, Mickaël Antoine Joseph, Jean-Christophe Comte, Pierre-Hervé Luppi, Paul-Antoine Libourel, Paul-Antoine Salin, Gaël Malleret, Régis Parmentier
STUDY OBJECTIVES: It is commonly accepted that sleep is beneficial to memory processes, but it is still unclear if this benefit originates from improved memory consolidation or enhanced information processing. It has thus been proposed that sleep may also promote forgetting of undesirable and non-essential memories, a process required for optimization of cognitive resources. We tested the hypothesis that non-rapid eye movement sleep (NREMS) promotes forgetting of irrelevant information, more specifically when processing information in working memory (WM), while REM sleep (REMS) facilitates the consolidation of important information...
October 10, 2016: Sleep
Robert G Averkin, Viktor Szemenyei, Sándor Bordé, Gábor Tamás
Ultra-high-frequency network events in the hippocampus are instrumental in a dialogue with the neocortex during memory formation, but the existence of transient ∼200 Hz network events in the neocortex is not clear. Our recordings from neocortical layer II/III of freely behaving rats revealed field potential events at ripple and high-gamma frequencies repeatedly occurring at troughs of spindle oscillations during sleep. Juxtacellular recordings identified subpopulations of fast-spiking, parvalbumin-containing basket cells with epochs of firing at ripple (∼200 Hz) and high-gamma (∼120 Hz) frequencies detected during spindles and centered with millisecond precision at the trough of spindle waves in phase with field potential events but phase shifted relative to pyramidal cell firing...
October 12, 2016: Neuron
Dong V Wang, Satoshi Ikemoto
: Hippocampal-cortical interaction during sleep promotes transformation of memory for long-term storage in the cortex. In particular, hippocampal sharp-wave ripple-associated neural activation is important for this transformation during slow-wave sleep. The anterior cingulate cortex (ACC) has been shown to be crucial for expression and likely storage of long-term memory. However, little is known about how ACC activity is influenced by hippocampal ripple activity during sleep. We report here about coordinated interactions between hippocampal ripple activity and ACC neural firings...
October 12, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Mariela Bettini, Hernan Gonorazky, Marcelo Chaves, Ernesto Fulgenzi, Alejandra Figueredo, Silvia Christiansen, Edgardo Cristiano, Enrico S Bertini, Marcelo Rugiero
Cases of acquired rippling muscle disease in association with myasthenia gravis have been reported. We present three patients with iRMD (immune-mediated rippling muscle disease) and AChR-antibody positive myasthenia gravis. None of them had thymus pathology. They presented exercise-induced muscle rippling combined with generalized myasthenia gravis. One of them had muscle biopsy showing a myopathic pattern and a patchy immunostaining with caveolin antibodies. They were successfully treated steroids and azathioprine...
October 15, 2016: Journal of Neuroimmunology
Shennan A Weiss, Iren Orosz, Noriko Salamon, Stephanie Moy, Linqing Wei, Maryse A Van't Klooster, Robert T Knight, Ronald M Harper, Anatol Bragin, Itzhak Fried, Jerome Engel, Richard J Staba
OBJECTIVE: Ripples (80-150 Hz) recorded from clinical macroelectrodes have been shown to be an accurate biomarker of epileptogenic brain tissue. We investigated coupling between epileptiform spike phase and ripple amplitude to better understand the mechanisms that generate this type of pathologic ripple (pRipple) event. METHODS: We quantified phase amplitude coupling (PAC) between epileptiform electroencephalography (EEG) spike phase and ripple amplitude recorded from intracranial depth macroelectrodes during episodes of sleep in 12 patients with mesial temporal lobe epilepsy...
October 10, 2016: Epilepsia
Shaun A Hussain, Gary W Mathern, Raman Sankar, Joyce Y Wu
OBJECTIVE: Fast ripples (FR, 250-500Hz) are proposed biomarkers of the epileptogenic zone on the basis of several retrospective reports linking postoperative seizure freedom to their complete resection. There are no clinical trials or prospective reports validating the use of FR as characterized by electrocorticography (ECoG), to guide the scope of epilepsy surgery, and to inform prognosis thereafter. We set out to prospectively evaluate the utility of FR resection to predict postoperative epilepsy outcomes, and examine the feasibility of "live" intraoperative FR ascertainment...
September 23, 2016: Epilepsy Research
Pia Maier, Martin E Kaiser, Valery Grinevich, Andreas Draguhn, Martin Both
The hypothalamic neuropeptide oxytocin (OT) controls childbirth and lactation, is involved in social behaviors, plays a role in various psychiatric disorders, and has effects on learning and memory. Although behavioral effects of OT have been extensively studied, much less is known about its effects on neuronal and network activity patterns. Here, we investigate the effect of OT on two major patterns of hippocampal network activity in mouse hippocampal slices. We studied different in vitro models of gamma-frequency oscillations and sharp wave-ripple complexes (SPW-R), two patterns implicated in spatial memory formation and memory consolidation respectively...
September 26, 2016: European Journal of Neuroscience
Rizwan Ul Haq, Marlene Anderson, Agustin Liotta, Maria Shafiq, Muhammad Azhar Sherkheli, Uwe Heinemann
Norepinephrine, is involved in the enhancement of learning and memory formation by regulating synaptic mechanisms through its ability to activate pre- and post-synaptic adrenergic receptors. Here we show that β-agonists of norepinephrine facilitate the induction of both associational LTP and sharp wave ripples (SPW-Rs) in acute slices of rat hippocampus in area CA3. Surprisingly, this facilitating effect persists when slices are only pretreated with β-receptor agonists followed by wash out and application of the unspecific β-adrenoreceptor (βAR) antagonist propranolol...
October 3, 2016: Hippocampus
Jesús Benito-Ruiz, Maria Luisa Manzano, Laura Salvador-Miranda
BACKGROUND: Form-stable 410 implants have the potential advantage of maintaining their anatomic form thanks to the cohesiveness of the gel. Furthermore, Biocell texturing appears to maximize adhesion and to allow for implant immobility. OBJECTIVES: To compare the rate of reoperations for transaxillary and periareolar approaches for breast augmentation. METHODS: This retrospective study consisted of 373 patients with a 5-year follow up. Patient demographics, self-perception and esteem, surgical technique, and implant characteristics were documented...
September 30, 2016: Aesthetic Surgery Journal
M W Gunathunga
BACKGROUND: Cognitive ergonomics in the work place has become a serious concern with the need to keep people happy at work while maintaining high productivity. Hence, it is worth exploring how the outcomes of lifestyle-based mind development programs can bring about happiness in workplace while keeping productivity and quality of services high. OBJECTIVE: The objective of the present work was to test a body-mind technique to improve cognitive ergonomics in a health care work setting...
October 17, 2016: Work: a Journal of Prevention, Assessment, and Rehabilitation
William J Ripple, James A Estes, Oswald J Schmitz, Vanessa Constant, Matthew J Kaylor, Adam Lenz, Jennifer L Motley, Katharine E Self, David S Taylor, Christopher Wolf
Few concepts in ecology have been so influential as that of the trophic cascade. Since the 1980s, the term has been a central or major theme of more than 2000 scientific articles. Despite this importance and widespread usage, basic questions remain about what constitutes a trophic cascade. Inconsistent usage of language impedes scientific progress and the utility of scientific concepts in management and conservation. Herein, we offer a definition of trophic cascade that is designed to be both widely applicable yet explicit enough to exclude extraneous interactions...
September 20, 2016: Trends in Ecology & Evolution
Hirohide Takahashi, Atsushi Miyagi, Lorena Redondo-Morata, Simon Scheuring
With nanometer lateral and Angstrom vertical resolution, atomic force microscopy (AFM) has contributed unique data improving the understanding of lipid bilayers. Lipid bilayers are found in several different temperature-dependent states, termed phases; the main phases are solid and fluid phases. The transition temperature between solid and fluid phases is lipid composition specific. Under certain conditions some lipid bilayers adopt a so-called ripple phase, a structure where solid and fluid phase domains alternate with constant periodicity...
September 20, 2016: Small
Mohamed Bougrine, Mohammed Benmiloud, Atallah Benalia, Emmanuel Delaleau, Mohamed Benbouzid
This paper is devoted to the development of a hybrid controller for a two-interleaved boost converter dedicated to renewable energy and automotive applications. The control requirements, resumed in fast transient and low input current ripple, are formulated as a problem of fast stabilization of a predefined optimal limit cycle, and solved using hybrid automaton formalism. In addition, a real time estimation of the load is developed using an algebraic approach for online adjustment of the hybrid controller. Mathematical proofs are provided with simulations to illustrate the effectiveness and the robustness of the proposed controller despite different disturbances...
September 16, 2016: ISA Transactions
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"