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Daniel Lachner Piza, Jonas C Bruder, Julia Jacobs, Andreas Schulze-Bonhage, Thomas Stieglitz, Matthias Dumpelmann, Daniel Lachner Piza, Jonas C Bruder, Julia Jacobs, Andreas Schulze-Bonhage, Thomas Stieglitz, Matthias Dumpelmann, Thomas Stieglitz, Matthias Dumpelmann, Jonas C Bruder, Andreas Schulze-Bonhage, Daniel Lachner Piza, Julia Jacobs
High Frequency Oscillations (HFOs) have been described as biomarkers of epileptogenic tissue; however their pathological/physiological classification poses a challenge to their predictive power. For the population of ripples co-occurring with sleep spindles, those ripples improving the antiparallel correlation of ripple-peaks and sleep spindle-troughs were classified as coupled-ripples and the rest as uncoupled-ripples. For the same population of ripples two reference groups called in-SOZ and non-SOZ were formed according to the ripples' location inside or outside the seizure onset zone (SOZ)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
M Shamas, P Benquet, I Merlet, W El Falou, M Khalil, F Wendling, M Shamas, P Benquet, I Merlet, W El Falou, M Khalil, F Wendling, M Khalil, P Benquet, I Merlet, W El Falou, M Shamas, F Wendling
High Frequency Oscillations (HFOs) are a potential biomarker of epileptogenic regions. They have been extensively investigated in terms of automatic detection, classification and feature extraction. However, the mechanisms governing the generation of HFOs as well as the observability conditions on clinical intracranial macroelectrodes remain elusive. In this paper, we propose a novel physiologically-relevant macroscopic model for accurate simulation of HFOs as invasively recorded in epileptic patients. This model accounts for both the temporal and spatial properties of the cortical patch at the origin of epileptiform activity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Carolyn J Brown, Eun-Kyung Jeon, Virginia Driscoll, Bruna Mussoi, Shruti Balvalli Deshpande, Kate Gfeller, Paul J Abbas
OBJECTIVE: Evidence suggests that musicians, as a group, have superior frequency resolution abilities when compared with nonmusicians. It is possible to assess auditory discrimination using either behavioral or electrophysiologic methods. The purpose of this study was to determine if the acoustic change complex (ACC) is sensitive enough to reflect the differences in spectral processing exhibited by musicians and nonmusicians. DESIGN: Twenty individuals (10 musicians and 10 nonmusicians) participated in this study...
March 2017: Ear and Hearing
Arnd Scheel, Angela Stevens
We study mechanisms for wavenumber selection in a minimal model for run-and-tumble dynamics. We show that nonlinearity in tumbling rates induces the existence of a plethora of traveling- and standing-wave patterns, as well as a subtle selection mechanism for the wavenumbers of spatio-temporally periodic waves. We comment on possible implications for rippling patterns observed in colonies of myxobacteria.
February 21, 2017: Journal of Mathematical Biology
Pan Jia, Bruno Andreotti, Philippe Claudin
Explaining the unexpected presence of dune-like patterns at the surface of the comet 67P/Churyumov-Gerasimenko requires conceptual and quantitative advances in the understanding of surface and outgassing processes. We show here that vapor flow emitted by the comet around its perihelion spreads laterally in a surface layer, due to the strong pressure difference between zones illuminated by sunlight and those in shadow. For such thermal winds to be dense enough to transport grains-10 times greater than previous estimates-outgassing must take place through a surface porous granular layer, and that layer must be composed of grains whose roughness lowers cohesion consistently with contact mechanics...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
Mozhgan Bizhang, Ilka Schmidt, Yong-Hee Patricia Chun, Wolfgang H Arnold, Stefan Zimmer
OBJECTIVE: The aim of this study was to evaluate the susceptibility of dentin to brushing abrasion using four different toothbrushes (rotating-oscillating, sonic and two types of manual toothbrushes) with the same brushing forces. METHODS: Dentin samples (n = 72) were selected from 72 impacted third molars. Half of the surface of dentin samples was covered with an adhesive tape, creating a protected and a freely exposed area in the same specimen. Brushing was performed with either a: sonic (Sonicare PowerUp, Philips GmbH, Hamburg, Germany), b: oscillating-rotating (Oral B Vitality Precisions Clean, Procter & Gamble, Schwalbach am Taunus, Germany) or two different manual toothbrushes c: flat trim brush head toothbrush (Dr...
2017: PloS One
Chun-Ting Wu, Daniel Haggerty, Caleb Kemere, Daoyun Ji
Hippocampal place cells are key to episodic memories. How these cells participate in memory retrieval remains unclear. After rats acquired a fear memory by receiving mild footshocks in a shock zone on a track, we analyzed place cells when the animals were placed on the track again and displayed an apparent memory retrieval behavior: avoidance of the shock zone. We found that place cells representing the shock zone were reactivated, despite the fact that the animals did not enter the shock zone. This reactivation occurred in ripple-associated awake replay of place cell sequences encoding the paths from the animal's current positions to the shock zone but not in place cell sequences within individual cycles of theta oscillation...
February 20, 2017: Nature Neuroscience
Christopher D Syme, Joanna Mosses, Mario González-Jiménez, Olga Shebanova, Finlay Walton, Klaas Wynne
Frustration of crystallisation by locally favoured structures is critically important in linking the phenomena of supercooling, glass formation, and liquid-liquid transitions. Here we show that the putative liquid-liquid transition in n-butanol is in fact caused by geometric frustration associated with an isotropic to rippled lamellar liquid-crystal transition. Liquid-crystal phases are generally regarded as being "in between" the liquid and the crystalline state. In contrast, the liquid-crystal phase in supercooled n-butanol is found to inhibit transformation to the crystal...
February 17, 2017: Scientific Reports
R E Cavicchi, Cayla Collett, Srivalli Telikepalli, Zhishang Hu, Michael Carrier, Dean C Ripple
An accurate assessment of particle characteristics and concentrations in pharmaceutical products by flow imaging requires accurate particle sizing and morphological analysis. Analysis of images begins with the definition of particle boundaries. Commonly a single threshold defines the level for a pixel in the image to be included in the detection of particles, but depending on the threshold level, this results in either missing translucent particles or oversizing of less transparent particles due to the halos and gradients in intensity near the particle boundaries...
February 13, 2017: Journal of Pharmaceutical Sciences
Liyong Zou, Jinhong Liu, Shenfei Liao, Xianxu Zheng, Zhigang Zhai, Xisheng Luo
The Richtmyer-Meshkov (RM) instability of a nominally flat interface (N_{2}/SF_{6}) subjected to a rippled shock, as the counterpart of a corrugated interface interacting with a planar shock, is studied experimentally in a vertical shock tube using both schlieren photography and fog visualization diagnostics. The nonplanar incident shock wave is produced by a planar shock diffracting around a rigid cylinder, and the flat interface is created by a membraneless technique. Three different distances η (the ratio of spacing from cylinder to interface over cylinder diameter) are considered...
January 2017: Physical Review. E
Han-Chun Wu, Alexander N Chaika, Ming-Chien Hsu, Tsung-Wei Huang, Mourad Abid, Mohamed Abid, Victor Yu Aristov, Olga V Molodtsova, Sergey V Babenkov, Yuran Niu, Barry E Murphy, Sergey A Krasnikov, Olaf Lübben, Huajun Liu, Byong Sun Chun, Yahya T Janabi, Sergei N Molotkov, Igor V Shvets, Alexander I Lichtenstein, Mikhail I Katsnelson, Ching-Ray Chang
Graphene supports long spin lifetimes and long diffusion lengths at room temperature, making it highly promising for spintronics. However, making graphene magnetic remains a principal challenge despite the many proposed solutions. Among these, graphene with zig-zag edges and ripples are the most promising candidates, as zig-zag edges are predicted to host spin-polarized electronic states, and spin-orbit coupling can be induced by ripples. Here we investigate the magnetoresistance of graphene grown on technologically relevant SiC/Si(001) wafers, where inherent nanodomain boundaries sandwich zig-zag structures between adjacent ripples of large curvature...
February 15, 2017: Nature Communications
Thomas J Bartosh
Relapse in cancer patients following an apparent cure and a prolonged latency period, known as tumor dormancy, remains an unrelenting clinical crisis. Here, I expand on our recent findings that potentially link cancer cell cannibalism of bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) to the senescence-associated secretory phenotype (SASP) and tumor dormancy.
2017: Molecular & Cellular Oncology
Cem Leblebici, Dincer Altinel, Merdan Serin, Oguzhan Okcu, Sevgi Kurt Yazar
Trichoblastic carcinoma (TC) is a rare type of malignancy which is derived from the hair follicles. In this paper, we report a case with TC on the scalp characterized with rippled pattern. There have been reports of rippled pattern in trichoblastomas, sebaceomas, and basal cell carcinomas. To the best of our knowledge, this is the first case in the literature to report a rippled pattern in TCs.
January 2017: Indian Journal of Pathology & Microbiology
Junaid A B Zaman, Christopher A B Kowalewski, Sanjiv M Narayan
Therapy for persistent atrial fibrillation (AF) is limited by uncertainty in its mechanisms yet, unlike in organized rhythms, mechanisms for AF may vary dramatically with mapping technique. The traditional approach of drawing contour maps of AF by assigning an onset time to each electrogram reveals disordered activity in patients with permanent AF at non-arrhythmia surgery.(1,2) This article is protected by copyright. All rights reserved.
February 10, 2017: Journal of Cardiovascular Electrophysiology
Haris M Ansari, Zhiyuan Niu, Chen Ge, Suliman A Dregia, Sheikh A Akbar
Spontaneous nanoripple formation on (110) surfaces of yttria-stabilized zirconia, YSZ-(110), is achieved by diffusional surface doping with rare-earth oxides. Periodic arrays of parallel nanobars separated by channels (period ∼100 nm) grow out of the dopant sources, covering relatively wide areas of the surface (∼10 μm). The nanobars mound up on the surface by diffusion, exhibiting morphological uniformity and alignment, with their long axis lying parallel to the [11̅0] direction in the YSZ-(110) surface...
February 9, 2017: ACS Nano
Ramon F Martin, Charles Rangira, Jeanne d'Arc Uwambazimana, Sukumar P Desai
Although the development of anesthesia as a specialty and its practice in Rwanda have occurred postindependence, there are several contributing factors that have had an impact on the current state of the delivery of anesthetic care. European colonization of Africa, in general, and Belgium's control, in particular, are primary factors that have had a significant impact on education. The ripple effect has had a long-lasting impact on health care as well as other facets of present-day Rwandan society. Tertiary education did not start until the latter half of the 20th century and has left this country with the belated development of an educated population in sufficient numbers to handle health care problems and provide sufficient care to its population...
January 2017: Journal of Anesthesia History
Claudio Villalobos, Pedro E Maldonado, José L Valdés
Spatial memory, among many other brain processes, shows hemispheric lateralization. Most of the published evidence suggests that the right hippocampus plays a leading role in the manipulation of spatial information. Concurrently in the hippocampus, memory consolidation during sleep periods is one of the key steps in the formation of newly acquired spatial memory traces. One of the most characteristic oscillatory patterns in the hippocampus are sharp-wave ripple (SWR) complexes. Within this complex, fast-field oscillations or ripples have been demonstrated to be instrumental in the memory consolidation process...
2017: PloS One
Johannes Stock, Anika Broemel, Johannes Hartung, Dennis Ochse, Herbert Gross
Freeform surfaces are becoming an increasingly exciting opportunity in optical design, in particular when correcting systems with off-axis geometries. Nevertheless, especially when coming to commercial use, the challenges for manufacturing are difficult to handle. The optical quality of a system is perturbed by typical deformations, such as localized figure errors and regular mid-spatial-frequency ripples, that come from the diamond-turning process. In this proposal, we investigated a workflow for analyzing the impact of real optical surfaces on the optical performance for even complex systems...
January 20, 2017: Applied Optics
David L Horn, Daniel J Dudley, Kavita Dedhia, Kaibao Nie, Ward R Drennan, Jong Ho Won, Jay T Rubinstein, Lynne A Werner
Spectral resolution limits speech perception with a cochlear implant (CI) in post-lingually deaf adults. However, the development of spectral resolution in pre-lingually deaf implanted children is not well understood. Acoustic spectral resolution was measured as a function of age (school-age versus adult) in CI and normal-hearing (NH) participants using spectral ripple discrimination (SRD). A 3-alternative forced-choice task was used to obtain SRD thresholds at five ripple depths. Effects of age and hearing method on SRD and spectral modulation transfer function (SMTF) slope (reflecting frequency resolution) and x-intercept (reflecting across-channel intensity resolution) were examined...
January 2017: Journal of the Acoustical Society of America
Mir Pouyan Zarabadi, François Paquet-Mercier, Steve J Charette, Jesse Greener
The anchoring biofilm layer is expected to exhibit a different response to environmental stresses than for portions in the bulk, due to the protection from other strata and the proximity to the attachment surface. The effect of hydrodynamic stress on surface-adhered biofilm layers was tested using a specially designed microfluidic bio flow cell with an embedded three-electrode detection system. In situ electrochemical impedance spectroscopy (EIS) measurements of biocapacitance and bioresistance of Pseudomonas sp...
February 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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