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https://www.readbyqxmd.com/read/29788801/perioperative-noninvasive-cardiac-output-monitoring-in-parturients-with-singleton-and-twin-pregnancies-undergoing-caesarean-section-under-spinal-anesthesia-with-prophylactic-phenylephrine-drip-a-prospective-observational-cohort-study
#1
S Orbach-Zinger, E Razinsky, I Bizman, S Firman, R Gat, A Davis, E Ashwal, A Shmueli, M Vaturi, R Gabbay-Benziv, L A Eidelman
INTRODUCTION: Spinal anesthesia is considered the gold standard anesthetic technique for cesarean deliveries (CD) but is associated with a high rate of hypotension. The recent international consensus recommends continuous prophylactic phenylephrine infusion (PPI) administered throughout CD to prevent hypotension. However little information is available on the hemodynamic profiles of women with twin pregnancies as compared to singleton pregnancies perioperatively. Therefore, in this study we aim we compare maternal hemodynamic changes both intraoperatively and postoperatively with the use of the NICAS bio impendence monitor in healthy singleton versus twin parturients undergoing CD deliveries with spinal anesthesia with PPI...
May 22, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29769570/in-utero-and-postnatal-exposure-to-high-fat-high-sucrose-diet-suppressed-testis-apoptosis-and-reduced-sperm-count
#2
Jiude Mao, Kathleen A Pennington, Omonseigho O Talton, Laura C Schulz, Miriam Sutovsky, Yan Lin, Peter Sutovsky
Obesity affects male fertility and maternal diabetes affects the offspring sperm epigenome. However, the effects of in utero exposure to maternal glucose intolerance in combination with postnatal high fat, high sucrose (HFHS) diet consumption on offspring spermatogenesis is not clear. The present study was designed to test these effects. One week before and during pregnancy, dams were fed either control or HFHS diet to induce gestational glucose intolerance, and returned to standard diet during lactation. Male offspring from each maternal group were split into control and HFHS-fed groups for eight weeks prior to sacrifice at 11, 19 or 31 weeks of age, and reproductive tissues were harvested for analysis of testicular germ cell apoptosis and sperm output...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29758458/effects-of-maternal-nutrient-restriction-followed-by-realimentation-during-early-and-mid-gestation-in-beef-cows-ii-placental-development-umbilical-blood-flow-and-uterine-blood-flow-responses-to-diet-alterations
#3
L E Camacho, C O Lemley, S T Dorsam, K C Swanson, K A Vonnahme
The objectives were to examine the effects of maternal nutrient restriction followed by realimentation during early to mid-gestation on placental development and uterine and umbilical hemodynamics in the beef cow. On day 30 of pregnancy, multiparous, non-lactating beef cows (620.5 ± 11.3 kg) were assigned to 1 of 2 dietary treatments: control (C; 100% National Research Council [NRC] recommendations; n = 18) and restricted (R; 60% NRC; n = 30). On day 85, cows were slaughtered (C, n = 6; R, n = 6), remained on control (CC; n = 12) and restricted (RR; n = 12), or were realimented to control (RC; n = 11)...
April 24, 2018: Theriogenology
https://www.readbyqxmd.com/read/29743872/pre-conceptional-and-peri-gestational-maternal-binge-alcohol-drinking-produces-inheritance-of-mood-disturbances-and-alcohol-vulnerability-in-the-adolescent-offspring
#4
Anna Brancato, Valentina Castelli, Angela Cavallaro, Gianluca Lavanco, Fulvio Plescia, Carla Cannizzaro
Although binge drinking is on the rise in women of reproductive age and during pregnancy, the consequences in the offspring, in particular the inheritance of alcohol-related mood disturbances and alcohol abuse vulnerability, are still poorly investigated. In this study, we modeled both Habitual- and Binge Alcohol Drinking (HAD and BAD) in female rats by employing a two-bottle choice paradigm, with 20% alcohol and water. The exposure started 12 weeks before pregnancy and continued during gestation and lactation...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29738792/energy-homeostasis-and-running-wheel-activity-during-pregnancy-in-the-mouse
#5
S R Ladyman, K M Carter, D R Grattan
Pregnancy and lactation are metabolically challenging states, where the mother must supply all the energy requirements for the developing fetus and growing pups respectively. The aim of the current study was to characterize many aspects of energy homeostasis before and during pregnancy in the mouse, and to examine the role of voluntary activity on changes in energy expenditure during pregnancy. In a secondary aim, we evaluate measures of energy homeostasis during pregnancy in mice that successfully reared their litter or in mice that went on to abandon their litter, to determine if an impairment in pregnancy-induced adaptation of energy homeostasis might underlie the abandonment of pups soon after birth...
May 5, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29729909/the-relationship-between-serum-anti-m%C3%A3-llerian-hormone-concentrations-and-fertility-and-genome-wide-associations-for-anti-m%C3%A3-llerian-hormone-in-holstein-cows
#6
M Gobikrushanth, D C Purfield, M G Colazo, S T Butler, Z Wang, D J Ambrose
The objectives of this study were to (1) evaluate factors associated with variation in circulating anti-Müllerian hormone (AMH) concentrations, (2) establish an optimum AMH threshold predictive of pregnancy to first artificial insemination (P/AI), (3) examine the relationship between AMH and fertility (P/AI, pregnancy loss between 30 and 60 d after artificial insemination, and pregnancy risk up to 250 d postpartum), and (4) identify quantitative trait loci associated with phenotypic variation of AMH concentrations in dairy cows...
May 2, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29725693/maternal-mortality-marital-status-and-bone-mineral-density-in-young-women-from-the-coimbra-identified-skeletal-collection
#7
Francisco Curate, Ana Tavares
In contemporary populations, pregnancy and lactation are usually followed by transient bone loss. The observation of reduced bone mass in young females from archaeological sites has sometimes been interpreted as an outcome of reproductive stress. In order to evaluate the overall effect of reproductive dynamics on bone mass in a historical skeletal sample, bone mineral density (BMD) at the proximal femur was assessed by dual-energy X-ray absorptiometry in 78 young women (17-39 years) from the Coimbra Identified Skeletal Collection...
May 3, 2018: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/29723099/exploring-healthy-eating-and-exercise-behaviors-among-low-income-breastfeeding-mothers
#8
Alexandra L MacMillan Uribe, Beth H Olson
BACKGROUND: Postpartum weight retention is often a significant contributor to overweight and obesity. Lactation is typically not sufficient for mothers to return to pre-pregnancy weight. Modifiable health behaviors (e.g., healthy eating and exercise) are important for postpartum weight loss; however, engagement among mothers, especially those who are resource-limited, is low. A deeper understanding of low-income breastfeeding mothers' healthy-eating and exercise experience, a population that may have unique motivators for health-behavior change, may facilitate creation of effective intervention strategies for these women...
April 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/29719312/contrast-agents-and-observing-patient-safety-programs-in-radiology-departments-in-kermanshah-province-hospitals-in-west-of-iran
#9
Fatemhe Amiri, Mohammad Rasoul Tohidnia, Somayeh Haydarizadi, Rasool Azmoonfar
Introduction: Contrast agents play an important role in increasing the efficiency of diagnostic imaging techniques in the evaluation of vascular lesions, infections and tumors. Annually more than 70 million radiology tests performed using contrast agent materials in the world. Side effects of contrast agent can belief-threaten, so that observing safety guideline prescribed a key role in the patient's health. Aim: The aim of this study was evaluation of compliance with the instructions in the use of contrast agent materials in Kermanshah province Hospitals, West in Iran...
2018: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29718478/developmental-exposure-to-a-mixture-of-23-chemicals-associated-with-unconventional-oil-and-gas-operations-alters-the-immune-system-of-mice
#10
Lisbeth A Boulé, Timothy J Chapman, Sara E Hillman, Christopher D Kassotis, Colleen O'Dell, Jacques Robert, Steve N Georas, Susan C Nagel, B Paige Lawrence
Chemicals used in unconventional oil and gas (UOG) operations have the potential to cause adverse biological effects, but this has not been thoroughly evaluated. A notable knowledge gap is their impact on development and function of the immune system. Herein, we report an investigation of whether developmental exposure to a mixture of chemicals associated with UOG operations affects the development and function of the immune system. We used a previously characterized mixture of 23 chemicals associated with UOG, and which was demonstrated to affect reproductive and developmental endpoints in mice...
May 1, 2018: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29717688/review-semen-handling-time-of-insemination-and-insemination-technique-in-cattle
#11
M G Diskin
In cattle artificial insemination plays not only a vital role in the successful establishment of pregnancy, which is a prerequisite for initiation of the subsequent lactation, but also in accelerating genetic improvement and facilitating the distribution of semen from genetically elite sires. The latter has been greatly facilitated by the ability to successfully cryopreserve semen. The objective of an insemination is to ensure that there is an adequate reservoir of competent, capacitated, motile sperm in the caudal region of the oviductal isthmus, the site of the main sperm reservoir in the cow, at the time of ovulation to ensure fertilisation...
May 2, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29705418/short-communication-serum-osteoprotegerin-concentrations-in-periparturient-dairy-cows
#12
Kaoru Hatate, Chiho Kawashima, Masaaki Hanada, Mitsunori Kayano, Norio Yamagishi
Dairy cows experience hypocalcemia at the onset of lactation; however, the contribution of bone metabolism to circulating Ca concentrations during the periparturient period is not well understood. Osteoprotegerin (OPG) protects against loss of skeletal mass by regulating osteoclastogenesis. We previously reported that the bone resorption increased around parturition in dairy cows from the perspective of bone markers in blood. The aim of this study was to explore osteoclastic bone resorption in periparturient dairy cows by measuring changes in serum OPG concentrations around calving...
April 25, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29702603/italian-association-of-clinical-endocrinologists-ame-and-italian-chapter-of-the-american-association-of-clinical-endocrinologists-aace-position-statement-clinical-management-of-vitamin-d-deficiency-in-adults
#13
Roberto Cesareo, Roberto Attanasio, Marco Caputo, Roberto Castello, Iacopo Chiodini, Alberto Falchetti, Rinaldo Guglielmi, Enrico Papini, Assunta Santonati, Alfredo Scillitani, Vincenzo Toscano, Vincenzo Triggiani, Fabio Vescini, Michele Zini
Vitamin D deficiency is very common and prescriptions of both assay and supplementation are increasing more and more. Health expenditure is exponentially increasing, thus it is timely and appropriate to establish rules. The Italian Association of Clinical Endocrinologists appointed a task force to review literature about vitamin D deficiency in adults. Four topics were identified as worthy for the practicing clinicians. For each topic recommendations based on scientific evidence and clinical practice were issued according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) System...
April 27, 2018: Nutrients
https://www.readbyqxmd.com/read/29701266/sex-specific-alterations-in-serology-and-the-expression-of-liver-fatp4-protein-in-offspring-exposed-to-high-fat-diet-during-pregnancy-and-or-lactation
#14
Mingqiu Zhao, Yi Li, Huihui Yao, Lihua Dou, Shuya Zhang, Qihong Zhao, Li Li
Changes in dietary composition will have a significant impact on the nutritional status of the mother and the offspring. To examine the relevant hormone level changes during lactation and the expression of fatty acid transporters in the placenta and liver under the condition of a high-fat (HF) diet, we established HF animal models and conducted a cross-fostering program to mimic the shift in diet. On gestation day (GD)18, the weight of placenta in the HF group was significantly higher than that in the control group (p < 0...
March 2018: Lipids
https://www.readbyqxmd.com/read/29699420/analysis-of-preventability-of-hypertensive-disorder-in-pregnancy-related-maternal-death-using-the-nationwide-registration-system-of-maternal-deaths-in-japan
#15
Shinji Katsuragi, Hiroaki Tanaka, Junichi Hasegawa, Masamitsu Nakamura, Naohiro Kanayama, Masahiko Nakata, Takeshi Murakoshi, Jun Yoshimatsu, Kazuhiro Osato, Kayo Tanaka, Akihiko Sekizawa, Isamu Ishiwata, Tomoaki Ikeda
OBJECTIVE: Hypertensive disorder of pregnancy (HDP) is a major cause of maternal death. The goal of this study was to investigate factors associated with maternal death due to HDP. STUDY DESIGN: HDP-related maternal deaths in Japan reported to the Committee of the Ministry of Health, Labor and Welfare from 2010 to 2015 were examined. RESULTS: Out of 47 cases of HDP, 30 were identified as the major cause of maternal death. The median maternal age was 34 years (range 24-45) and the mortality in women aged ≥40 years was seven times higher that than in women aged <34 years...
April 26, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29688495/supplementing-ca-salts-of-soybean-oil-after-artificial-insemination-increases-pregnancy-success-in-bos-taurus-beef-cows
#16
A P Brandão, R F Cooke, K M Schubach, R S Marques, D W Bohnert, R S Carvalho, N W Dias, C L Timlin, S Clark-Deener, J F Currin, D B Jump, K G Pohler, R L A Cerri, V R G Mercadante
Two experiments investigated the effects of supplementing Ca salts of soybean oil (CSSO) during early gestation on reproductive function and pregnancy rates to artificial insemination (AI) in Bos taurus beef cows. In Exp. 1, 771 suckled, lactating, multiparous Angus cows were divided into 22 groups of approximately 35 cows/group, and timed-inseminated on d 0. After AI, groups were assigned randomly to receive (as-fed basis) 100 g of ground corn + 100 g of soybean meal per cow/d, in addition to: 1) 100 g/cow daily of CSSO (n = 11), or 2) 87 g of prilled saturated fat + 13 g of limestone per cow/d (CON; n = 11)...
April 24, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29685149/rationale-for-environmental-hygiene-towards-global-protection-of-fetuses-and-young-children-from-adverse-lifestyle-factors
#17
Jean-Pierre Bourguignon, Anne-Simone Parent, Jos C S Kleinjans, Tim S Nawrot, Greet Schoeters, Nicolas Van Larebeke
BACKGROUND: The regulatory management of chemicals and toxicants in the EU addresses hundreds of different chemicals and health hazards individually, one by one. An issue is that, so far, the possible interactions among chemicals or hazards are not considered as such. Another issue is the anticipated delay of several decades before effective protection of public health by regulatory decisions due to a time consuming process. Prenatal and early postnatal life is highly vulnerable to environmental health hazards with lifelong consequences, and a priority period for reduction of exposure...
April 23, 2018: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/29685073/the-association-of-second-trimester-biomarkers-in-amniotic-fluid-and-fetal-outcome
#18
Irene Sterpu, Peter Anfelter, Susan Wray, Helena Kaihola, Helena Åkerud, Eva Wiberg-Itzel
OBJECTIVE: To identify the level of amniotic fluid lactate (AFL), placental growth factor (PLGF) and vascular endothelial growth factor (VEGF) at second trimester amniocentesis, and to compare levels in normal pregnancies with pregnancies ending in a miscarriage, an intrauterine growth restricted fetus (IUGR) or decreased fetal movements. STUDY DESIGN: A prospective cohort study. Amniotic fluid was consecutive collected at amniocentesis in 106 pregnancies. Fetal wellbeing at delivery was evaluated from medical files and compared with the levels of AFL, VEGF and PLGF at the time of amniocentesis...
April 23, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29680084/no-197b-fetal-health-surveillance-intrapartum-consensus-guideline
#19
Robert Liston, Diane Sawchuck, David Young
OBJECTIVE: This guideline provides new recommendations pertaining to the application and documentation of fetal surveillance in the intrapartum period that will decrease the incidence of birth asphyxia while maintaining the lowest possible rate of obstetrical intervention. Pregnancies with and without risk factors for adverse perinatal outcomes are considered. This guideline presents an alternative classification system for antenatal fetal non-stress testing and intrapartum electronic fetal surveillance to what has been used previously...
April 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29677199/implications-of-current-therapeutic-restrictions-for-primaquine-and-tafenoquine-in-the-radical-cure-of-vivax-malaria
#20
James Watson, Walter R J Taylor, Germana Bancone, Cindy S Chu, Podjanee Jittamala, Nicholas J White
BACKGROUND: The 8-aminoquinoline antimalarials, the only drugs which prevent relapse of vivax and ovale malaria (radical cure), cause dose-dependent oxidant haemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. Patients with <30% and <70% of normal G6PD activity are not given standard regimens of primaquine and tafenoquine, respectively. Both drugs are currently considered contraindicated in pregnant and lactating women. METHODS: Quantitative G6PD enzyme activity data from 5198 individuals were used to estimate the proportions of heterozygous females who would be ineligible for treatment at the 30% and 70% activity thresholds, and the relationship with the severity of the deficiency...
April 20, 2018: PLoS Neglected Tropical Diseases
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