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post polio syndrome medication

Markus Bleckwenn, Klaus Weckbecker, Sebastian Voss
HISTORY AND CLINICAL FINDINGS:  We report a 79-year-old patient with post-polio syndrome (PPS). In the course of this disease, recurrent upper abdominal pain and a therapy-resistant nausea developed without vomiting. In addition, the patient was limited by the combination of muscular weakness, obesity, dietary-treated diabetes and a degenerative spinal cord injury significantly in its mobility and physical capacity. INVESTIGATIONS AND DIAGNOSIS:  Despite extensive diagnostics, no somatic cause could be found neither for the nausea nor for the upper abdominal pain...
March 2018: Deutsche Medizinische Wochenschrift
Carolyn P Da Silva, Bianca Zuckerman, Rhoda Olkin
The purpose of this study was to determine if falls in polio survivors, with or without post-polio syndrome (PPS), are related to number of medications taken, use of anti-depressant or psychoactive medications, or self-report of depression. A survey was sent to 300 members of a regional polio support group, asking them to document their fall history, medications used, and the presence of depression. Depression was measured by self-report and with the Geriatric Depression Scale, short form (GDS-15). One hundred and seventy-two usable surveys were returned with 146 of those completing the medication list...
May 2017: Physiotherapy Theory and Practice
L Bertolasi, A Danese, S Monaco, M Turri, K Borg, L Werhagen
BACKGROUND: Poliomyelitis was before the immunization an important medical problem. Nowadays polio prior patients (PP) suffer from polio sequelae or have developed post-polio-syndrome (PPS) with increasing paresis, pain and fatigue. OBJECTIVES: To analyze the medical situation 50 years after acute polio. The degree of paresis was compared between the recovery 1952-1961 and 2012.The prevalence of patients fulfilling the criteria for PPS was estimated. METHOD: The study was performed in Italy...
2016: Open Neurology Journal
Amanda E Smith, Ivan R Molton, Mark P Jensen
BACKGROUND: Adults with long-term disability are living longer and may experience accelerated aging. More information is needed to understand the incidence of chronic comorbid medical conditions in this population. OBJECTIVE: To examine the incidence, prevalence, age of onset and predictors of five chronic conditions in a sample of adults with long-term physical disability. METHODS: Longitudinal self-report surveys were mailed to 1594 adults with multiple sclerosis, muscular dystrophy, post-polio syndrome or spinal cord injury twice, 3...
July 2016: Disability and Health Journal
Gunilla Östlund, Lisbet Broman, Lars Werhagen, Kristian Borg
OBJECTIVE: To define and characterize responders and non-responders in a group of 124 patients with post-polio syndrome who received a single treatment with intravenous immunoglobulin. DESIGN: Open trial, prospective follow-up study. METHODS: Clinical examination and data from medical records. Short Form 36 (SF-36), Physical Activity Scale for the Elderly (PASE) and visual analogue scale (VAS) measured quality of life, physical activity and intensity of pain, respectively...
September 2015: Journal of Rehabilitation Medicine
Eun Joo Yang, Seung Yeol Lee, Keewon Kim, Se Hee Jung, Soong-Nang Jang, Soo Jeong Han, Wan-Ho Kim, Jae-Young Lim
The purpose of this study is to assess health-related quality of life in polio survivors (PS) compared with that in the general population in Korea. Polio survivors (n = 120) from outpatient clinics at two hospitals, healthy controls (HC, n = 121) and members of the general population with activity limitations (AL, n = 121) recruited through a proportional-allocation, systematic sampling strategy from the Fourth Korean National Health and Nutrition Examination Survey were surveyed with self-rated health-related quality of life (Euro QoL five-dimensions)...
2015: PloS One
Asma Zorgati, Khaled Maaref, Nader Naouar, Afif Zaoui, Slaheddine Ghannouchi
BACKGROUND: The diagnosis of the post polio syndrome is purely clinic. It occurs few decade after poliomyelitis. It associates recent appearance or progressive worsening of muscular weakness, pain, muscular fatigue or atrophy. It remains not recognized in Tunisia. AIM: of our study is to identify the socio-medical profile of the postpolio population in the Tunisian east central region through a check of the risk factors and the clinical characteristics of these patients...
August 2014: La Tunisie Médicale
Shimon Shiri, Irina Gartsman, Zeev Meiner, Isabella Schwartz
OBJECTIVE: To compare the psychological health of the individuals with long-standing poliomyelitis, with or without post-polio syndrome (PPS), to the general population and to identify the role of work as well as other variables with regard to their psychological health. DESIGN: A cross-sectional study. SUBJECTS: One hundred and ninety-five polio patients attending postpolio clinic in Jerusalem. METHODS: Emotional distress (ED) was measured using the general health questionnaire (GHQ-12)...
2015: Disability and Rehabilitation
Hyun Bang, Jee Hyun Suh, Seung Yeol Lee, Keewon Kim, Eun Joo Yang, Se Hee Jung, Soong-Nang Jang, Soo Jeong Han, Wan-Ho Kim, Min-Gyun Oh, Jeong-Hwan Kim, Sam-Gyu Lee, Jae-Young Lim
OBJECTIVE: To obtain information on the socioeconomic, medical, and functional status of polio survivors, and to use these results as the preliminary data for establishing the middle-aged cohort of polio survivors. METHODS: The subjects were recruited based on the medical records of multiple hospitals and centers. They were assessed through a structured questionnaire over the phone. Post-poliomyelitis syndrome (PPS) was identified according to the specified diagnostic criteria...
October 2014: Annals of Rehabilitation Medicine
Isabella Schwartz, Irina Gartsman, Bella Adler, Yechiel Friedlander, Orly Manor, Hagai Levine, Zeev Meiner
OBJECTIVE: To evaluate the association between self-reported severity of polio sequelae and current functional status among polio survivors. METHODS: This was a cross sectional study of 195 polio survivors attending a polio outpatient clinic at a university hospital. The main outcome measures of demographic, medical, social, and functional data were gleaned from a questionnaire adapted for the polio population. The severity of polio sequelae was evaluated with the self-reported Index of Post-Polio Sequelae (IPPS)...
October 15, 2014: Journal of the Neurological Sciences
David W Allison, Jeffrey H Gertsch, Mark A Mahan, Geoffrey L Sheean, Justin M Brown
UNLABELLED: The use of transcranial motor evoked potentials (TCMEPs) to detect and hopefully prevent injury to the brain, spinal cord, and peripheral nerves intraoperatively has increased greatly in recent years. It is well established that in addition to certain anesthetic agents, patient factors such as advanced age, obesity, diabetes, hypertension, and a collection of neurological and neuromuscular diseases and disorders can greatly reduce or completely eliminate the ability to monitor TCMEPs effectively...
March 2014: Neurodiagnostic Journal
Ziad A Memish, Abdullah Assiri, Malak Almasri, Rafat F Alhakeem, Abdulhafeez Turkestani, Abdullah A Al Rabeeah, Jaffar A Al-Tawfiq, Abdullah Alzahrani, Essam Azhar, Hatem Q Makhdoom, Waleed H Hajomar, Ali M Al-Shangiti, Saber Yezli
BACKGROUND: Annually, Saudi Arabia is the host of the Hajj mass gathering. We aimed to determine the Middle East respiratory syndrome coronavirus (MERS-CoV) nasal carriage rate among pilgrims performing the 2013 Hajj and to describe the compliance with the Saudi Ministry of Health vaccine recommendations. METHOD: Nasopharyngeal samples were collected from 5235 adult pilgrims from 22 countries and screened for MERS-CoV using reverse transcriptase-polymerase chain reaction...
October 1, 2014: Journal of Infectious Diseases
D A Trojan, L Finch
Many patients with post-poliomyelitis syndrome can benefit from a management program. When a post-polio patient presents with new symptoms, it is first essential to identify and treat other medical and neurological conditions which could produce these symptoms. New weakness can be managed with exercise (stretching, strengthening, and aerobic), avoidance of muscular overuse, weight loss, orthoses, and assistive devices. Fatigue can be managed with energy conservation techniques, lifestyle changes, pacing, regular rest periods or naps during the day, amitriptyline to improve sleep, and possibly pyridostigmine (trial in progress)...
1997: NeuroRehabilitation
A C Gawne, L S Halstead
Paralytic poliomyelitis has plagued mankind for centuries. The incidence of acute paralytic poliomyelitis dramatically declined in 1955 only after the introduction of the inactivated polio vaccine. Post-Polio Syndrome (PPS) was described as early as the 1870s, but was not clearly recognized by the medical community until the early 1980s. This article reviews the history and epidemiology of acute paralytic poliomyelitis, as well as post-polio syndrome, from its early description by Charcot and others in 1875, to the modern roots of PPS research in 1954...
1997: NeuroRehabilitation
Ivan R Molton, Alexandra L Terrill, Amanda E Smith, Kathryn M Yorkston, Kevin N Alschuler, Dawn M Ehde, Mark P Jensen
OBJECTIVES: To test a conceptual model of secondary health conditions, age, and function in persons aging with long-term physical disabilities. METHODS: Surveys were collected from 1,862 adults with spinal cord injury, neuromuscular disease, multiple sclerosis, or post-polio syndrome. Structural equation modeling was used to build a model describing relationships among physical and psychosocial secondary health conditions, pain, functional impairments, chronic medical conditions, and age...
April 2014: Journal of Aging and Health
Jesús Esteban
In 1875 M. Raymond described a progressive muscle wasting and weakness in 3 individuals survivors of childhood acute poliomyelitis. Jean-Martin Charcot suggested that the initial injury should let these guys neurons more sensitive to develop posterior spinal diseases and new weakness was the result of overuse of the affected muscles. In 1979, after the publication of the description given by a 57 year old patient on motor difficulties that developed after suffering of polio in childhood, there was a very significant increase of comments of other individuals with similar symptoms, reaching wedged in the 80s the term of post-polio syndrome...
September 2013: Revista Española de Salud Pública
Ping Sheng, Lijun Hou, Xiang Wang, Xiaowen Wang, Chengguang Huang, Mingkun Yu, Xi Han, Yan Dong
BACKGROUND: Modafinil is a novel wake-promoting agent approved by the FDA ameliorating excessive daytime sleepiness (EDS) in three disorders: narcolepsy, shift work sleep disorder and obstructive sleep apnea. Existing trials of modafinil for fatigue and EDS associated with neurological disorders provided inconsistent results. This meta-analysis was aimed to assess drug safety and effects of modafinil on fatigue and EDS associated with neurological disorders. METHODS: A comprehensive literature review was conducted in order to identify published studies assessing the effects of modafinil on fatigue and EDS associated with neurological disorders...
2013: PloS One
Ewa Matyja
The care of patients with post-polio syndrome ought to be carried out by a multidisciplinary team of specialists, including medical professionals, specialists of rehabilitation, psychologists and social workers. Many therapeutic strategies might be employed to reduce the late effects of polio. Today, the management of post-polio syndrome is based on non-pharmacological intervention, including lifestyle modification, decrease of physical activity, rest periods during the day and an individually tailored training program...
July 2012: Neurologia i Neurochirurgia Polska
Gunilla Ostlund, Lisbet Broman, Lars Werhagen, Kristian Borg
The aim of this work is to evaluate the outcome of IVIG treatment in patients with post-polio syndrome (PPS) and to identify responders. The study included 113 PPS patients who had received one IVIG treatment in an open trial, prospective follow-up study. Clinical examination was performed and clinical data were retrieved from medical records. The short form 36 (SF-36), physical activity scale for the elderly (PASE), and the visual analogue scale (VAS) were used as measurements of quality of life, physical activity, and the intensity of pain...
December 2012: Journal of Neurology
Kathryn M Yorkston, Kara A McMullan, Ivan Molton, Mark P Jensen
PURPOSE: To examine the issues related to aging with disability from the perspective of the person with the disabilities. METHOD: Twelve community-dwelling adults with spinal cord injury (SCI), post-polio syndrome (PPS) or multiple sclerosis (MS) participated in focus groups where they were asked open-ended questions about changes related to aging with disability, accommodations made and perspectives on the future. RESULTS: Results of qualitative analysis suggested five major themes related to aging with a disability: (1) Participant identity, including comments about how participants described themselves and their lives with a long-standing disability; (2) Physical pathways including comments about the progression of physical symptoms; (3) Psychosocial pathways, including descriptions of adaptations to disability, the development of emotional well-being and strategies to deal with disability; (4) Changing health care, reflecting improvement noted over time in health care services; and (5) Concerns about the future, including comments reflecting participant uncertainty about the potential course of disability...
2010: Disability and Rehabilitation
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