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https://www.readbyqxmd.com/read/28444501/validation-of-numerical-simulation-methods-in-aortic-arch-using-4d-flow-mri
#1
Shohei Miyazaki, Keiichi Itatani, Toyoki Furusawa, Teruyasu Nishino, Masataka Sugiyama, Yasuo Takehara, Satoshi Yasukochi
Computational fluid dynamics (CFD) are the gold standard in studying blood flow dynamics. However, CFD results are dependent on the boundary conditions and the computation model. The purpose of this study was to validate CFD methods using comparison with actual measurements of the blood flow vector obtained with four-dimensional (4D) flow magnetic resonance imaging (MRI). 4D Flow MRI was performed on a healthy adult and a child with double-aortic arch. The aortic lumen was segmented to visualize the blood flow...
April 25, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28437388/international-liver-transplantation-society-consensus-statement-on-hepatitis-c-management-in-liver-transplant-recipients
#2
Norah A Terrault, Marina Berenguer, Simone I Strasser, Adrian Gadano, Les Lilly, Didier Samuel, Paul Y Kwo, Kosh Agarwal, Michael P Curry, Stefano Fagiuoli, James Y Y Fung, Edward Gane, Kimberly A Brown, Patrizia Burra, Michael Charlton, Mario G Pessoa, Geoff W McCaughan
No abstract text is available yet for this article.
May 2017: Transplantation
https://www.readbyqxmd.com/read/28437387/international-liver-transplantation-society-consensus-statement-on-hepatitis-c-management-in-liver-transplant-candidates
#3
Norah A Terrault, Geoff W McCaughan, Michael P Curry, Edward Gane, Stefano Fagiuoli, James Y Y Fung, Kosh Agarwal, Les Lilly, Simone I Strasser, Kimberly A Brown, Adrian Gadano, Paul Y Kwo, Patrizia Burra, Didier Samuel, Michael Charlton, Mario G Pessoa, Marina Berenguer
No abstract text is available yet for this article.
May 2017: Transplantation
https://www.readbyqxmd.com/read/28435264/efficient-co-delivery-of-immiscible-hydrophilic-hydrophobic-chemotherapeutics-by-lipid-emulsions-for-improved-treatment-of-cancer
#4
Bo Zhang, Yunmei Song, Tianqi Wang, Shaomei Yang, Jing Zhang, Yongjun Liu, Na Zhang, Sanjay Garg
Combinational nanomedicine is becoming a topic of much interest in cancer therapy, although its translation into the clinic remains extremely challenging. One of the main obstacles lies in the difficulty to efficiently co-deliver immiscible hydrophilic/hydrophobic drugs into tumor sites. The aim of this study was to develop co-loaded lipid emulsions (LEs) to co-deliver immiscible hydrophilic/hydrophobic drugs to improve cancer therapy and to explore the co-delivery abilities between co-loaded LEs and mixture formulation...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28430956/achieving-high-reliability-in-histology-%C3%A2-an-improvement-series-to-reduce-errors
#5
Yael K Heher, Yigu Chen, Sergey Pyatibrat, Edward Yoon, Jeffrey D Goldsmith, Kenneth E Sands
Objectives: Despite sweeping medical advances in other fields, histology processes have by and large remained constant over the past 175 years. Patient label identification errors are a known liability in the laboratory and can be devastating, resulting in incorrect diagnoses and inappropriate treatment. The objective of this study was to identify vulnerable steps in the histology workflow and reduce the frequency of labeling errors (LEs). Methods: In this 36-month study period, a numerical step key (SK) was developed to capture LEs...
November 1, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28428706/gastroesophageal-reflux-disease-and-morbid-obesity-to-sleeve-or-not-to-sleeve
#6
EDITORIAL
Fabrizio Rebecchi, Marco E Allaix, Marco G Patti, Francisco Schlottmann, Mario Morino
Laparoscopic sleeve gastrectomy (LSG) has reached wide popularity during the last 15 years, due to the limited morbidity and mortality rates, and the very good weight loss results and effects on comorbid conditions. However, there are concerns regarding the effects of LSG on gastroesophageal reflux disease (GERD). The interpretation of the current evidence is challenged by the fact that the LSG technique is not standardized, and most studies investigate the presence of GERD by assessing symptoms and the use of acid reducing medications only...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28426463/treatments-for-achalasia-in-2017-how-to-choose-among-them
#7
Peter J Kahrilas, John E Pandolfino
PURPOSE OF REVIEW: To review recent advances in achalasia diagnostics and therapeutics. RECENT FINDINGS: The cardinal feature of achalasia, impaired lower esophageal sphincter (LES) relaxation, can occur in association with varied patterns of esophageal contractility. The Chicago Classification distinguishes among these as follows: without contractility (type I), with panesophageal pressurization (type II), with premature (spastic) distal esophageal contractions (type III), or even with preserved peristalsis [esophagogastric junction (EGJ) outlet obstruction]...
April 19, 2017: Current Opinion in Gastroenterology
https://www.readbyqxmd.com/read/28425900/mobiliser-des-repr%C3%A3-sentations-ethnoculturelles-pour-expliquer-les-disparit%C3%A3-s-d%C3%A2-acc%C3%A3-s-aux-soins-de-sant%C3%A3-au-burkina-faso
#8
Loubna Belaid, Patrick Cloos, Valéry Ridde
OBJECTIFS: Cette étude vise à décrire la mobilisation des représentations ethnoculturelles par des agents et des gestionnaires de santé pour expliquer l'échec partiel d'une politique de santé maternelle et discuter des conséquences potentielles de ces représentations sur l'accès aux soins de santé des populations.MÉTHODES : Il s'agit d'une recherche qualitative de type socio-anthropologique mobilisant des entretiens approfondis, des discussions informelles, des observations non participantes menées dans les centres de santé et une analyse documentaire...
April 20, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28421801/actitudes-de-escolares-chilenos-de-distinto-nivel-socioecon%C3%A3-mico-al-inicio-de-la-implementaci%C3%A3-n-de-la-ley-que-regula-la-venta-y-publicidad-de-alimentos-altos-en-nutrientes-cr%C3%A3-ticos
#9
Sonia Olivares Cortes, Jacqueline Araneda Flores, Gladys Morales Illanes, Bárbara Leyton Dinamarca, Nelly Bustos Zapata, María Angélica Hernández Moreno, María Teresa Oyarzún Macchiavello
Introducción: el 27 de junio de 2016 se implementó en Chile la Ley sobre Composición Nutricional de los Alimentos y su Publicidad, que implica rotular el envase de los alimentos procesados, altos en calorías, grasas saturadas, azúcares y sodio.Objetivo: determinar las actitudes de escolares de 8 a 12 años, de distinto nivel socioeconómico (NSE) y estado nutricional, ante el nuevo etiquetado de los alimentos.Métodos: se aplicó una encuesta validada previamente, agregando preguntas sobre los nuevos sellos en los envases de alimentos y bebidas...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28421789/in%C3%AF-uencia-del-aceite-de-coco-en-enfermos-de-alzh%C3%A3-imer-a-nivel-cognitivo
#10
José Enrique De la Rubia Ortí, Carmen Sánchez Álvarez, Pablo Selvi Sabater, Alma María Bueno Cayo, Sandra Sancho Castillo, Mariano Julián Rochina, Iván Hu Yang
Introducción: la enfermedad de Alzheimer es a día de hoy la demencia neurodegenerativa con mayor prevalencia en el primer mundo. Este hecho, unido a la falta de tratamiento farmacológico que cure la enfermedad, hace que se estudien nuevas estrategias terapéuticas no farmacológicas como es la administración de nutrientes. En este sentido, destaca la posible influencia del aceite de coco como fuente energética alternativa, capaz de frenar la muerte neuronal que se produce de modo progresivo en esta enfermedad...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28418429/chemical-constituents-radical-scavenging-activity-and-enzyme-inhibitory-capacity-of-fruits-from-cotoneaster-pannosus-franch
#11
Francisco Les, Víctor López, Giovanni Caprioli, Romilde Iannarelli, Dennis Fiorini, Marzia Innocenti, Maria Bellumori, Filippo Maggi
Cotoneaster pannosus (Rosaceae) is a semievergreen shrub, producing globose dark red pomes, native to China and widely used as an ornamental plant all over the world. Despite its extensive cultivation, little information is available on the chemical composition and biological activities of its fruits. In this work, the analysis of the chemical composition of C. pannosus fruits, in terms of phenolic components, carotenoids and ascorbic acid by HPLC/DAD, HPLC/ESI-MS and MS/MS as well as in terms of macro- and micro-nutrients was performed...
April 18, 2017: Food & Function
https://www.readbyqxmd.com/read/28416923/esophageal-achalasia-predictive-value-of-preoperative-resting-pressure-of-les-correlated-with-type-of-fundoplication
#12
Antonio Tancredi, Antonello Cuttitta, Roberto Scaramuzzi, Gerardo Scaramuzzi, Marco Taurchini
OBJECTIVE: The aim of the present study is to show the predictive value of the preoperative resting pressure of the lower esophageal sphincter (LES) correlated with the type of fundoplication (Nissen or Dor) after Heller myotomy in our series. MATERIALS AND METHODS: From January 1998 to June 2010, 88 patients affected by esophageal achalasia underwent surgery at our unit. However, our study focused on a sample of 36 patients, because many data were lost or was never recorded...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28415265/comparative-statistics-of-selected-subgrid-scale-models-in-large-eddy-simulations-of-decaying-supersonic-magnetohydrodynamic-turbulence
#13
Philipp Grete, Dimitar G Vlaykov, Wolfram Schmidt, Dominik R G Schleicher
Large-eddy simulations (LES) are a powerful tool in understanding processes that are inaccessible by direct simulations due to their complexity, for example, in the highly turbulent regime. However, their accuracy and success depends on a proper subgrid-scale (SGS) model that accounts for the unresolved scales in the simulation. We evaluate the applicability of two traditional SGS models, namely the eddy-viscosity (EV) and the scale-similarity (SS) models, and one recently proposed nonlinear (NL) SGS model in the realm of compressible magnetohydrodynamic (MHD) turbulence...
March 2017: Physical Review. E
https://www.readbyqxmd.com/read/28413043/n-o-329-consensus-canadien-sur-la-contraception-4-e-%C3%A2-partie-de-4-chapitre-9-%C3%A2-contraception-hormonale-combin%C3%A3-e
#14
Amanda Black, Edith Guilbert, Dustin Costescu, Sheila Dunn, William Fisher, Sari Kives, Melissa Mirosh, Wendy V Norman, Helen Pymar, Robert Reid, Geneviève Roy, Hannah Varto, Ashley Waddington, Marie-Soleil Wagner, Anne Marie Whelan
OBJECTIF: Mettre à la disposition des fournisseurs de soins des lignes directrices concernant le recours à des méthodes contraceptives pour prévenir la grossesse et la promotion d'une sexualité saine. ISSUES: Efficacité globale des méthodes contraceptives citées : évaluation de l'innocuité, des effets indésirables et de la baisse du taux de grossesse; effet des méthodes contraceptives citées sur la santé sexuelle et le bien-être général; disponibilité des méthodes contraceptives citées au Canada...
April 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28412344/insights-into-structure-and-function-of-high-pressure-modified-starches-with-different-crystalline-polymorphs
#15
Jinrong Wang, Huaping Zhu, Sha Li, Shujun Wang, Shuo Wang, Les Copeland
The effect of high pressure (HP) treatment at 200-600MPa for 30min on properties of three starches with different polymorphs was investigated. HP treatment altered greatly the morphology of wheat starch, especially at 400MPa or higher. The crystallinity of wheat starch decreased from 22.6% for native starch to 3.4% for starch after treatment at 600MPa. The short-range molecular order as measured by FTIR and Raman spectroscopy decreased with increasing treatment pressure. HP treatment had little effect on structural properties of potato and yam starches, except for yam starch after treatment at 600MPa...
April 13, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28409498/differential-pro-apoptotic-effects-of-synthetic-4-thiazolidinone-derivative-les-3288-doxorubicin-and-temozolomide-in-human-glioma-u251-cells
#16
Lesya I Коbylinska, Olga Yu Klyuchivska, Iryna I Grytsyna, Natalia Finiuk, Rostyslav R Panchuk, Marina O Starykovych, Lilya Lehka, Roman B Lesyk, Borys S Zіmenkovsky, Rostyslav S Stoika
AIM: To compare various pro-apoptotic effects of synthetic 4-thiazolidinone derivative (Les-3288), doxorubicin (Dox) and temozolomide (TMZ) in the treatment of human glioma U251 cells to improve treatment outcomes of glioblastoma and avoid anticancer drug resistance. METHODS: The cytotoxic effects of drugs used in human glioma U251 cells were measured by cell viability and proliferation assay (MTT), Trypan blue exclusion test, and Western-blot analysis of the apoptosis-related proteins...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28409496/4-thiazolidinone-derivative-les-3833-effectively-inhibits-viability-of-human-melanoma-cells-through-activating-apoptotic-mechanisms
#17
Nataliya Finiuk, Nataliya Boiko, Olga Klyuchivska, Lesya Коbylinska, Iryna Kril, Borys Zimenkovsky, Roman Lesyk, Rostyslav Stoika
AIM: To evaluate cytotoxic action of 4-thiazolidinone derivative Les-3833 and study the mechanisms of its pro-apoptotic action toward human melanoma cells and human tumor cell lines of other tissue origin. METHODS: The effect of Les-3833 or doxorubicin on the viability of 9 cell lines was studied using MTT assay, while human melanoma cells of WM793 line were additionally examined using light and fluorescent microscopies for evaluating cytomorphological changes. The Western-blot and flow cytometric analyses were carried out to study signaling pathways of melanoma cell cycling and death...
April 14, 2017: Croatian Medical Journal
https://www.readbyqxmd.com/read/28408767/prevalence-and-correlates-of-physical-dating-violence-among-north-american-indigenous-adolescents
#18
Dane S Hautala, Kelley J Sittner Hartshorn, Brian Armenta, Les Whitbeck
This study examined the lifetime prevalence of physical dating violence, including victimization, perpetration, and the overlap between the two (mutual violence) among a population sample of 551 reservation/reserve residing Indigenous (i.e., American Indian and Canadian First Nations) adolescents in the upper-Midwest of the United States and Canada. Potential correlates of four dating violence profiles (i.e., no dating violence, perpetration-only, victimization-only, and mutual violence) relevant to this population also were considered...
April 2017: Youth & Society
https://www.readbyqxmd.com/read/28404133/effect-on-hbs-antigen-clearance-of-addition-of-pegylated-interferon-alfa-2a-to-nucleos-t-ide-analogue-therapy-versus-nucleos-t-ide-analogue-therapy-alone-in-patients-with-hbe-antigen-negative-chronic-hepatitis-b-and-sustained-undetectable-plasma-hepatitis-b
#19
Marc Bourlière, Pascaline Rabiega, Nathalie Ganne-Carrie, Lawrence Serfaty, Patrick Marcellin, Yoann Barthe, Dominique Thabut, Dominique Guyader, Christophe Hezode, Magali Picon, Xavier Causse, Vincent Leroy, Jean Pierre Bronowicki, Patrizia Carrieri, Ghassan Riachi, Isabelle Rosa, Pierre Attali, Jean Michel Molina, Yannick Bacq, Albert Tran, Jean Didier Grangé, Fabien Zoulim, Hélène Fontaine, Laurent Alric, Inga Bertucci, Magali Bouvier-Alias, Fabrice Carrat
BACKGROUND: Findings from uncontrolled studies suggest that addition of pegylated interferon in patients with HBe antigen (HBeAg)-negative chronic hepatitis B receiving nucleos(t)ide analogues with undetectable plasma hepatitis B virus (HBV) DNA might increase HBs antigen (HBsAg) clearance. We aimed to assess this strategy. METHODS: In this randomised, controlled, open-label trial, we enrolled patients aged 18-75 years with HBeAg-negative chronic hepatitis B and documented negative HBV DNA while on stable nucleos(t)ide analogue regimens for at least 1 year from 30 hepatology tertiary care wards in France...
March 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28403730/runaway-inequality-leopold-les-2015-runaway-inequality-an-activist-s-guide-to-economic-justice-new-york-ny-labor-institute-press-314-pp-19-95-pbk-isbn-9780692436301
#20
Harris Gruman
No abstract text is available yet for this article.
May 2017: New Solutions: a Journal of Environmental and Occupational Health Policy: NS
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