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https://www.readbyqxmd.com/read/29332231/stage-specific-therapeutic-strategies-of-medication-related-osteonecrosis-of-the-jaws-a-systematic-review-and-meta-analysis-of-the-drug-suspension-protocol
#1
REVIEW
Luca Ramaglia, Agostino Guida, Vincenzo Iorio-Siciliano, Alessandro Cuozzo, Andrea Blasi, Anton Sculean
OBJECTIVE: The most debated topic about medication-related osteonecrosis of the jaws (MRONJ) is its therapy, as there are no definitive guidelines. The aims of this systematic review were (a) to outline the best therapeutic approach according to the stage at diagnosis and (b) to perform a meta-analysis to assess whether the drug-holiday protocol may be or not an effective method in the management of MRONJ patients. MATERIALS AND METHODS: The systematic review was performed following the PRISMA principles...
January 13, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29331365/assessment-of-test-retest-reliability-of-a-food-choice-task-among-healthy-individuals
#2
Karin Foerde, Loren Gianini, Yuanjia Wang, Peng Wu, Daphna Shohamy, B Timothy Walsh, Joanna E Steinglass
Aberrations in eating patterns constitute a substantial public health burden. Computer-based paradigms that measure responses to images of foods are potentially useful tools for assessing food attitudes and characteristics of eating behavior. In particular, food choice tasks attempt to directly probe aspects of individuals' decisions about what to eat. In the Food Choice Task participants rate the healthiness and tastiness of a variety of food items presented one at a time. Next, participants choose for each food item whether they prefer to eat the item vs...
January 10, 2018: Appetite
https://www.readbyqxmd.com/read/29324557/factors-influencing-participation-in-fecal-occult-blood-testing-to-screen-for-colorectal-cancer-in-australia-a-scoping-review-protocol
#3
Simone Lee, Andrea Miller
The objective of this scoping review is to examine and map the evidence on the range of factors influencing a person's decision to screen or not screen for colorectal cancer using a fecal occult blood test (FOBT) in Australia, with the view to identifying gaps in the research and informing appropriate questions for future systematic reviews.The question of this review is: what evidence is available around the barriers and facilitators that influence an individual's decision to screen or not screen for colorectal cancer using a fecal occult blood test in Australia?...
January 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29317467/evaluating-team-decision-making-as-an-emergent-phenomenon
#4
John Kinnear, Nick Wilson, Anthony O'Dwyer
BACKGROUND: The complexity of modern clinical practice has highlighted the fallibility of individual clinicians' decision-making, with effective teamwork emerging as a key to patient safety. Dual process theory is widely accepted as a framework for individual decision-making, with type 1 processes responsible for fast, intuitive and automatic decisions and type 2 processes for slow, analytical decisions. However, dual process theory does not explain cognition at the group level, when individuals act in teams...
January 9, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29289528/cystic-fibrosis-colorectal-cancer-screening-consensus-recommendations
#5
Denis Hadjiliadis, Alexander Khoruts, Ann G Zauber, Sarah E Hempstead, Patrick Maisonneuve, Albert B Lowenfels
BACKGROUND & AIMS: Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5-10 times greater compared to the general population, and 25-30 times greater in CF patients after an organ transplantation. To address this risk, the CF Foundation convened a multi-stakeholder task force to develop CRC screening recommendations. METHODS: The 18-member task force consisted of experts including pulmonologists, gastroenterologists, a social worker, nurse coordinator, surgeon, epidemiologist, statistician, CF adult, and a parent...
December 28, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29285867/quality-competition-and-hospital-mergers-an-experiment
#6
Johann Han, Nadja Kairies-Schwarz, Markus Vomhof
On the basis of a Salop model with regulated prices, we investigate quality provision behaviour of competing hospitals before and after a merger. For this, we use a controlled laboratory experiment where subjects decided on the level of treatment quality as head of a hospital. We find that the post-merger average quality is significantly lower than the average pre-merger quality. However, for merger insiders and outsiders, average quality choices are significantly higher than predicted for pure profit-maximising hospitals...
December 2017: Health Economics
https://www.readbyqxmd.com/read/29284757/autologous-stem-cell-transplantation-in-elderly-lymphoma-patients-in-their-70s-outcomes-and-analysis
#7
Lova Sun, Shuli Li, Areej El-Jawahri, Philippe Armand, Bimalangshu R Dey, David C Fisher, Eric D Jacobsen, Caron A Jacobson, Ann S LaCasce, Steven L McAfee, Thomas R Spitzer, Yi-Bin Chen, Zachariah DeFilipp
BACKGROUND: High-dose chemotherapy and autologous stem cell transplantation (ASCT) can offer durable remission in many patients with relapsed or high-risk lymphoma. However, elderly patients are often not considered ASCT candidates based on age alone. SUBJECTS, MATERIALS, AND METHODS: A retrospective analysis of patients ≥70 years of age with a diagnosis of Hodgkin or non-Hodgkin lymphoma receiving ASCT between 2000 and 2016 at two partner institutions was performed...
December 28, 2017: Oncologist
https://www.readbyqxmd.com/read/29260244/-the-use-of-tumor-therapeutics-in-the-perioperative-period
#8
REVIEW
V Luber, J Wagner, J F Lock, U A Dietz, S Lichthardt, N Matthes, K Krajinovic, C-T Germer, A Wiegering, S Knop
In 2010 Germany had 447,300 new cases of cancer. From 2000 to 2010 the incidence of cancer increased by 21% in men and by 14% in women. The change in the age structure with an aging population is the crucial influencing factor. Various cancer types can now be treated by oral antitumor agents used as a chronic medication. Physicians must decide whether the oral antitumor agents can be continued perioperatively or if certain drugs must be paused and if so, with what risks. Oral antitumor agents are a very heterogeneous group of medication...
December 19, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29237857/using-knowledge-from-human-research-to-improve-understanding-of-contest-theory-and-contest-dynamics
#9
REVIEW
Michael M Kasumovic, Khandis Blake, Thomas F Denson
Our understanding of animal contests and the factors that affect contest dynamics and decisions stems from a long and prosperous collaboration between empiricists and theoreticians. Over the last two decades, however, theoretical predictions regarding the factors that affect individual decisions before, during and after a contest are becoming increasingly difficult to test empirically. Extremely large sample sizes are necessary to experimentally test the nuanced theoretical assumptions surrounding how information is used by animals during a contest, how context changes the information used, and how individuals change behaviour as a result of both the information available and the context in which the information is acquired...
December 20, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29218265/the-role-of-imaging-and-radiation-oncology-core-for-precision-medicine-era-of-clinical-trial
#10
Ying Xiao, Mark Rosen
Imaging and Radiation Oncology Core (IROC) services have been established for the quality assurance (QA) of imaging and radiotherapy (RT) for NCI's Clinical Trial Network (NCTN) for any trials that contain imaging or RT. The randomized clinical trial is the gold standard for evidence-based medicine. QA ensures data quality, preventing noise from inferior treatments obscuring clinical trial outcome. QA is also found to be cost-effective. IROC has made great progress in multi-institution standardization and is expected to lead QA standardization, QA science in imaging and RT and to advance quality data analysis with big data in the future...
December 2017: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/29194876/rational-decision-making-in-medicine-implications-for-overuse-and-underuse
#11
Benjamin Djulbegovic, Shira Elqayam, William Dale
In spite of substantial spending and resource utilization, today's health care remains characterized by poor outcomes, largely due to overuse (overtesting/overtreatment) or underuse (undertesting/undertreatment) of health services. To a significant extent, this is a consequence of low-quality decision making that appears to violate various rationality criteria. Such suboptimal decision making is considered a leading cause of death and is responsible for more than 80% of health expenses. In this paper, we address the issue of overuse or underuse of health care interventions from the perspective of rational choice theory...
December 1, 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29167657/choices-regarding-thrombolysis-are-modified-by-the-way-to-transfer-the-messages
#12
Jingjing Gong, Yan Zhang, Hongyan Gao, Wei Wei, Jing Lv, Hongyun Liu, Yonghua Huang
Although thrombolysis is the most effective medical treatment for acute ischemic stroke, many stroke patients eligible for thrombolysis miss this treatment as a result of delay or refusal by the patients and/or their proxies. To explore the influences of prognostic information for different intervals from stroke onset to the start of thrombolytic treatment (OTT) and other factors on the preferences of patients/proxies regarding thrombolytic therapy, a cross-sectional, discrete-choice experiment was performed between August 2013 and September 2014...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29152598/study-protocol-a-randomized-controlled-trial-of-a-comprehensive-breast-cancer-treatment-patient-decision-tool-icandecide
#13
Sarah T Hawley, Yun Li, L Alexandra Jeanpierre, Stefanie Goodell, Reshma Jagsi, Kevin C Ward, Michael S Sabel, Steven J Katz
Background: Patients newly diagnosed with breast cancer face a series of complex decisions regarding locoregional and systemic treatment. There is a need to improve the quality of locoregional and systemic decisions for breast cancer patients, and to help patients understand the role of evaluative tests in this decision process. We are now conducting a randomized controlled trial (RCT) of an online decision tool-called iCanDecide, which we expect will help patients with these difficult decisions...
March 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29148087/an-agent-based-model-of-evolving-community-flood-risk
#14
Gina L Tonn, Seth D Guikema
Although individual behavior plays a major role in community flood risk, traditional flood risk models generally do not capture information on how community policies and individual decisions impact the evolution of flood risk over time. The purpose of this study is to improve the understanding of the temporal aspects of flood risk through a combined analysis of the behavioral, engineering, and physical hazard aspects of flood risk. Additionally, the study aims to develop a new modeling approach for integrating behavior, policy, flood hazards, and engineering interventions...
November 17, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29132985/validation-of-kdri-kdpi-for-the-selection-of-expanded-criteria-kidney-donors
#15
Juan Antonio Retamero Díaz, Mercedes Cava Molina, Belen M Cobacho Tornel, Juan Bravo Soto, Antonio Osuna Ortega, Francisco O'Valle Ravassa, Raimundo García Del Moral Garrido
INTRODUCTION: KDRI / KDPI are tools use in kidney donor evaluation. It has been proposed as a substitute of, or complementary to preimplantation renal biopsy. These scores has not been validated in Spain. OBJECTIVE: 1) To investigate the concordance between KDPI and histological scores (preimplantation renal biopsy) and 2) To assess the relationship between KDRI, KDPI and histological score on graft survival in the expanded criteria donors group. METHODOLOGY: Retrospective cohort study from 1 January 1998 until 31 December 2010...
November 10, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29126361/a-survey-of-the-current-practice-of-intramuscular-botulinum-toxin-injections-for-hemiplegic-shoulder-pain-in-the-uk
#16
Richard J Holmes, Louise A Connell
PURPOSE: To describe the current UK practice for the use of intramuscular Botulinum Toxin type A injections to treat hemiplegic shoulder pain. METHOD: A UK-based cross-sectional study using an online survey. Participants (n = 68) were medical and non-medical practitioners recruited via the membership of the British Society for Rehabilitation Medicine and the British Neurotoxin Network. Data was analysed using descriptive statistics and content analysis. RESULTS: The majority of respondents would consider Botulinum Toxin type A for hemiplegic shoulder pain (86...
November 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29118329/aortic-stiffness-improves-the-prediction-of-both-diagnosis-and-severity-of-coronary-artery-disease
#17
Alexandra Yannoutsos, Mathieu Ahouah, Céline Dreyfuss Tubiana, Jirar Topouchian, Michel E Safar, Jacques Blacher
Elective coronography has low diagnostic yield for obstructive coronary artery disease (CAD). We aim to determine whether non-invasive aortic stiffness assessment improves diagnostic accuracy of CAD screening by reducing the number of false-positive results from the cardiac stress test. A cross-sectional study was conducted from January 2013 to September 2014 in our medical center. Electrocardiogram (ECG) stress test coupled with nuclear imaging was performed in 367 consecutive patients routinely followed for myocardial ischemia screening...
November 9, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29102532/prospects-for-pro-environmental-protein-consumption-in-europe-cultural-culinary-economic-and-psychological-factors
#18
Joop de Boer, Harry Aiking
The current ratio between plant and animal protein in the Western diet is causing serious threats to both public health and the environment. Healthy, pro-environmental protein consumption requires a transition to a diet with more plant protein and considerably less animal protein. The present paper focuses on the prospects of this transition by analyzing consumer responses to some key options in the context of regional differences across Europe. The aim is to assess how responses to the options might be shaped by 1) cultural, culinary and economic spatial gradients (including GDP per capita) at regional level and 2) differences in environmental friendly behavior and gender at individual level...
November 2, 2017: Appetite
https://www.readbyqxmd.com/read/29095951/perceptual-judgments-made-better-by-indirect-interactions-evidence-from-a-joint-localization-task
#19
Pavel Valeryevich Voinov, Natalie Sebanz, Günther Knoblich
Others' perceptual judgments tend to have strong effects on our own, and can improve perceptual judgments when task partners engage in communication. The present study investigated whether individuals benefit from others' perceptual judgments in indirect interactions, where outcomes of individual decisions can be observed in a shared environment. Participants located a target in a 2D projection of a 3D container either from two complementary viewpoints (Experiment 1), or from a single viewpoint (Experiment 2)...
2017: PloS One
https://www.readbyqxmd.com/read/29093518/ant-droplet-dynamics-evolve-via-individual-decision-making
#20
Tomoko Sakiyama
The droplets of a set of ants were studied while they constructed a bridge. A droplet is a group of ants derived from a larger group. Several experimental studies have revealed the droplet dynamics of ants that resemble the self-organising characteristics that are displayed in their physico-chemical systems. However, little is known regarding how these typical behaviours emerge from individual decision-making. In this study, I developed an agent-based model where artificial ants aggregated, thereby resulting in chain and droplet growth...
November 1, 2017: Scientific Reports
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