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https://www.readbyqxmd.com/read/29046039/topical-review-transitional-services-for-teens-and-young-adults-with-attention-deficit-hyperactivity-disorder-a-process-map-and-proposed-model-to-overcoming-barriers-to-care
#1
Jason M Fogler, David Burke, James Lynch, William J Barbaresi, Eugenia Chan
Objective: To provide a topical review of the personal vulnerabilities and systemic barriers facing transitional age young adults with attention-deficit hyperactivity disorder (ADHD), followed by a proposed model for overcoming those barriers. Methods: Drawing from a growing, but limited, literature on the topic, we outline a process map for identifying and troubleshooting barriers to care in this at-risk population. Results: Young adults with ADHD frequently lack the organizational skills, time management, prioritization, and persistence to manage their health care at an expected level of adult independence...
November 1, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29045699/impact-of-hiv-on-the-burden-and-severity-of-influenza-illness-in-malawian-adults-a-prospective-cohort-and-parallel-case-control-study
#2
Antonia Ho, Stephen J Aston, Hannah Jary, Tamara Mitchell, Maaike Alaerts, Mavis Menyere, Jane Mallewa, Mulinda Nyirenda, Dean Everett, Robert S Heyderman, Neil French
Background: The impact of HIV infection on influenza incidence and severity in adults in sub-Saharan Africa is unclear. Seasonal influenza vaccination is recommended for HIV-infected persons in developed settings, but is rarely implemented in Africa. Methods: We conducted a prospective cohort study to compare the incidence of laboratory-confirmed influenza illness between HIV-infected and HIV-uninfected adults in Blantyre, Malawi. In a parallel case-control study, we explored risk factors for severe influenza presentation of severe (hospitalized lower respiratory tract infection (LRTI)), and mild influenza (influenza-like illness (ILI))...
October 16, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29045645/predictors-of-antimalarial-self-medication-in-illegal-gold-miners-in-french-guiana-a-pathway-towards-artemisinin-resistance
#3
M Douine, Y Lazrek, D Blanchet, S Pelleau, R Chanlin, F Corlin, L Hureau, B Volney, H Hiwat, S Vreden, F Djossou, M Demar, M Nacher, L Musset
Background: Malaria is endemic in French Guiana (FG), South America. Despite the decrease in cases in the local population, illegal gold miners are very affected by malaria (22.3% of them carried Plasmodium spp.). Self-medication seems to be very common, but its modalities and associated factors have not been studied. The aim of this study was to evaluate parasite susceptibility to drugs and to document behaviours that could contribute to resistance selection in illegal gold miners. Methods: This multicentric cross-sectional study was conducted in resting sites along the FG-Surinamese border...
October 17, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29045556/age-race-and-gender-factors-in-incident-disability
#4
Mini E Jacob, Megan M Marron, Robert Boudreau, Michelle C Odden, Alice M Arnold, Anne B Newman
Background: Incident disability rates enable the comparison of risk across populations. Understanding these by age, sex and race is important for planning for the care of older adults and targeting prevention. Methods: We calculated incident disability rates among older adults in the Cardiovascular Health Study, a study of 5,888 older adults aged ≥ 65 years over 6 years of follow-up. Disability was defined in 2 ways: 1) self-report of disability (severe difficulty or inability) in any of 6 ADLs, and 2) mobility difficulty (any difficulty walking half a mile or climbing 10 steps)...
October 13, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29045506/clinical-and-molecular-characterization-of-patients-with-cancers-of-unknown-primary-in-the-modern-era
#5
A M Varghese, A Arora, M Capanu, N Camacho, H H Won, A Zehir, J Gao, D Chakravarty, N Schultz, D S Klimstra, M Ladanyi, D M Hyman, D B Solit, M F Berger, L B Saltz
Background: On the basis of historical data, patients with cancers of unknown primary (CUP) are generally assumed to have a dismal prognosis with overall survival of less than one year. Treatment is typically cytotoxic chemotherapy guided by histologic features and the pattern of metastatic spread. The purpose of this study was to provide a clinical and pathologic description of patients with CUP in the modern era, to define the frequency of clinically actionable molecular alterations in this population, to determine how molecular testing can alter therapeutic decisions, and to investigate novel uses of next generation sequencing in the evaluation and treatment of patients with CUP...
September 26, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29044897/a-comparison-of-dietary-estimates-from-the-national-aboriginal-and-torres-strait-islander-health-survey-to-food-and-beverage-purchase-data
#6
Emma McMahon, Thomas Wycherley, Kerin O'Dea, Julie Brimblecombe
OBJECTIVE: We compared self-reported dietary intake from the very remote sample of the National Aboriginal and Torres Strait Islander Nutrition and Physical Activity Survey (VR-NATSINPAS; n=1,363) to one year of food and beverage purchases from 20 very remote Indigenous Australian communities (servicing ∼8,500 individuals). METHODS: Differences in food (% energy from food groups) and nutrients were analysed using t-test with unequal variance. RESULTS: Per-capita energy estimates were not significantly different between the surveys (899 MJ/person/day [95% confidence interval -152,1950] p=0...
October 18, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29044885/heritability-and-social-brood-effects-on-personality-in-juvenile-and-adult-life-history-stages-in-a-wild-passerine
#7
Isabel S Winney, Julia Schroeder, Shinichi Nakagawa, Yu-Hsun Hsu, Mirre Jp Simons, Alfredo Sánchez-Tójar, Maria-Elena Mannarelli, Terry Burke
How has evolution led to the variation in behavioural phenotypes (personalities) in a population? Knowledge of whether personality is heritable, and to what degree it is influenced by the social environment, is crucial to understanding its evolutionary significance, yet few estimates are available from natural populations. We tracked three behavioural traits during different life-history stages in a pedigreed population of wild house sparrows. Using a quantitative genetic approach, we demonstrated heritability in adult exploration, and in nestling activity after accounting for fixed effects, but not in adult boldness...
October 17, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/29044846/socio-demographic-factors-drive-regional-differences-in-participation-in-the-national-bowel-cancer-screening-program-an-ecological-analysis
#8
Jiandong Sun, Sonja March, Michael J Ireland, Fiona Crawford-Williams, Belinda Goodwin, Melissa K Hyde, Suzanne K Chambers, Joanne F Aitken, Jeff Dunn
OBJECTIVE: To examine if geographic variations in the participation rates in the National Bowel Cancer Screening Program (NBCSP) are related to population-level socio-demographic characteristics. METHODS: Data reflecting participation in the NBCSP for 504 Local Government Areas (LGAs) between July 2011 and June 2013 were extracted from the Social Health Atlas of Australia. Logistic regression models were used to examine independent associations (odds ratios [ORs]) between participation, Remoteness Area (RA) and selected socio-demographic variables...
October 18, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/29044769/human-papillomavirus-vaccination-of-adult-women-and-risk-of-autoimmune-and-neurological-diseases
#9
A Hviid, H Svanström, N M Scheller, O Grönlund, B Pasternak, L Arnheim-Dahlström
BACKGROUND: Since 2006, human papillomavirus (HPV) vaccines have been introduced in many countries worldwide. Whilst safety studies have been reassuring, focus has been on the primary target group, the young adolescent girls. However, it is also important to evaluate safety in adult women where background disease rates and safety issues could differ significantly. OBJECTIVE: We took advantage of the unique Danish and Swedish nationwide healthcare registers to conduct a cohort study comparing incidence rate ratios (RRs) of 45 preselected serious chronic diseases in quadrivalent HPV (qHPV)-vaccinated and qHPV-unvaccinated adult women 18-44 years of age...
October 18, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29044687/incident-ischaemic-stroke-and-type-2-diabetes-trends-in-incidence-and-case-fatality-in-scotland-2004-2013
#10
S H Read, D A McAllister, H M Colhoun, B Farran, C Fischbacher, J J Kerssens, G P Leese, R S Lindsay, R J McCrimmon, S McGurnaghan, S Philip, N Sattar, S H Wild
AIM: To describe trends in first ischaemic stroke incidence and case fatality in adults with and without a diagnosis of Type 2 diabetes prior to their ischaemic stroke event in Scotland between 2004 and 2013. METHODS: Using population-wide hospital admission, death and diabetes datasets, we conducted a retrospective cohort study. Negative binomial and logistic regression models were used to calculate year-specific incidence and case-fatality rates for people with Type 2 diabetes and for people without diabetes...
October 17, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29044626/the-cost-effectiveness-of-cognitive-behavioral-therapy-for-bulimia-nervosa-in-the-australian-context
#11
Long Khanh-Dao Le, Phillipa Hay, Tracey Wade, Stephen Touyz, Cathrine Mihalopoulos
OBJECTIVE: This study was to model the cost-effectiveness of specialist-delivered cognitive behavioral therapy for bulimia nervosa (CBT-BN) compared to no intervention within the Australian context. METHOD: An illness-death model was developed to estimate the cost per disability-adjusted life-year (DALY) averted of CBT-BN over 2 years from the healthcare perspective. Target population was adults aged 18-65 years with BN. Results are reported as incremental cost-effectiveness ratios (ICER) in 2013 Australian dollars per DALY averted...
October 16, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/29044586/males-with-prolactinoma-are-at-increased-risk-of-incident-cardiovascular-disease
#12
Konstantinos A Toulis, Tim Robbins, Narendra Reddy, Balachandran Kumarendran, Krishna Gokhale, Haren Wijesinghe, Kar Keung Cheng, Niki Karavitaki, John Wass, Krishnarajah Nirantharakumar
OBJECTIVE: To investigate whether the risk of incident cardiovascular disease (CVD) is increased in patients with prolactinoma. DESIGN: Population-based, retrospective, open-cohort study using The Health Improvement Network (THIN) database. PATIENTS: 2,233 patients with prolactinoma and 10,355 matched controls (1:5 ratio) from UK General Practices contributing to THIN were included. Sex, age, body mass index, and smoking status were used as matching parametres...
October 16, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29044477/association-between-neighborhood-cohesion-and-self-neglect-in-chinese-american-older-adults
#13
Ailian Hei, XinQi Dong
OBJECTIVES: To examine the association between neighborhood cohesion and risk of self-neglect in a community-dwelling Chinese-American older population. SETTING: Community. PARTICIPANTS: Chinese-American older adults aged 60 and older interviewed from 2011 to 2013 (N = 3,159). DESIGN: Data were drawn from the Population Study of Chinese Elderly, a cross-sectional community-engaged study in the greater Chicago area...
October 17, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29044463/prehospital-delay-in-older-adults-with-acute-myocardial-infarction-the-comprehensive-evaluation-of-risk-factors-in-older-patients-with-acute-myocardial-infarction-study
#14
Gregory M Ouellet, Mary Geda, Terrence E Murphy, Sui Tsang, Mary E Tinetti, Sarwat I Chaudhry
BACKGROUND/OBJECTIVES: Timely administration of antiischemic therapies improves outcomes in individuals with acute myocardial infarction (AMI). Prior literature on delays in AMI care has largely focused on in-hospital delay ("door to balloon" time). Our objective was to identify factors associated with prehospital delay in a contemporary national cohort of older adults with AMI. DESIGN: Cross-sectional analysis of data from the ComprehenSIVe Evaluation of Risk Factors in Older Patients with Acute Myocardial Infarction (SILVER-AMI) study, an observational study of older adults hospitalized for AMI...
October 18, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29044457/secondary-prevention-medication-use-after-myocardial-infarction-in-u-s-nursing-home-residents
#15
Andrew R Zullo, Sadia Sharmin, Yoojin Lee, Lori A Daiello, Nishant R Shah, W John Boscardin, David D Dore, Sei J Lee, Michael A Steinman
BACKGROUND/OBJECTIVES: Secondary prevention medications are recommended for older adults after acute myocardial infarction (AMI), but little is known about whether nursing home (NH) residents receive these medications. The objective was to evaluate new use of secondary prevention medications after AMI in NH residents who were previously nonusers and to evaluate what factors were associated with use. DESIGN: Retrospective cohort using linked national Minimum Data Set assessments; Online Survey, Certification and Reporting records; and Medicare claims...
October 17, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29043831/del-phenotype
#16
Dong H Kwon, S G Sandler, Willy A Flegel
DEL red blood cells (RBCs) type as D- by routine serologic methods and are transfused routinely, without being identified as expressing a very weak D antigen, to D- recipients. DEL RBCs are detected only by adsorption and elution of anti-D or by molecular methods. Most DEL phenotypes have been reported in population studies conducted in East Asia, although DEL phenotypes have been detected also among Caucasian individuals. Approximately 98 percent of DEL phenotypes in East Asians are associated with the RHD*DEL1 or RHD*01EL...
September 2017: Immunohematology
https://www.readbyqxmd.com/read/29043609/the-fat-of-the-matter-obesity-and-visceral-adiposity-in-treated-hiv-infection
#17
REVIEW
Jordan E Lake
PURPOSE OF REVIEW: The aim of this review is to summarize knowledge of the prevalence, relevant physiology, and consequences of obesity and visceral adiposity in HIV-infected adults, including highlighting gaps in current knowledge and future research directions. RECENT FINDINGS: Similar to the general population, obesity prevalence is increasing among HIV-infected persons, and obesity and visceral adiposity are associated with numerous metabolic and inflammatory sequelae...
October 18, 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29043008/ancestors-dietary-patterns-and-environments-could-drive-positive-selection-in-genes-involved-in-micronutrient-metabolism-the-case-of-cofactor-transporters
#18
Silvia Parolo, Sébastien Lacroix, Jim Kaput, Marie-Pier Scott-Boyer
BACKGROUND: During evolution, humans colonized different ecological niches and adopted a variety of subsistence strategies that gave rise to diverse selective pressures acting across the genome. Environmentally induced selection of vitamin, mineral, or other cofactor transporters could influence micronutrient-requiring molecular reactions and contribute to inter-individual variability in response to foods and nutritional interventions. METHODS: A comprehensive list of genes coding for transporters of cofactors or their precursors was built using data mining procedures from the HGDP dataset and then explored to detect evidence of positive genetic selection...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/29042825/antithrombotics-in-trauma-management-strategies-in-the-older-patients
#19
REVIEW
Henna Wong, Nicola Lovett, Nicola Curry, Ku Shah, Simon J Stanworth
The ageing population has resulted in a change in the demographics of trauma, and older adult trauma now accounts for a growing number of trauma admissions. The management of older adult trauma can be particularly challenging, and exhibits differences to that of the younger age groups affected by trauma. Frailty syndromes are closely related with falls, which are the leading cause of major trauma in older adults. Comorbid disease and antithrombotic use are more common in the older population. Physiological changes that occur with ageing can alter the expected clinical presentation of older persons after injury and their susceptibility to injury...
2017: Journal of Blood Medicine
https://www.readbyqxmd.com/read/29042378/association-between-polypharmacy-and-falls-in-older-adults-a-longitudinal-study-from-england
#20
Nafeesa N Dhalwani, Radia Fahami, Harini Sathanapally, Sam Seidu, Melanie J Davies, Kamlesh Khunti
OBJECTIVES: Assess the longitudinal association between polypharmacy and falls and examine the differences in this association by different thresholds for polypharmacy definitions in a nationally representative sample of adults aged over 60 years from England. DESIGN: Longitudinal cohort study. SETTING: The English Longitudinal Study of Ageing waves 6 and 7. PARTICIPANTS: 5213 adults aged 60 or older. MAIN OUTCOME MEASURES: Rates, incidence rate ratio (IRR) and 95% CI for falls in people with and without polypharmacy...
October 16, 2017: BMJ Open
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