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ischemic mitral valve

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https://www.readbyqxmd.com/read/27920591/left-atrial-myxomectomy-with-intraoperative-severe-mitral-regurgitation-and-complicated-postoperative-course-case-report
#1
Nareg Minaskeian, Patrick P Hu
Primary cardiac tumors are a rare occurrence with myxomas accounting for about half of the benign tumors. Once diagnosed, surgical resection is the standard of care. Our case describes a female in her 50s who underwent a myxoma resection under cardiopulmonary bypass via biatrial approach. Intraoperatively, the thin septal crux between the wall of the aorta and mitral valve was damaged during resection, requiring stem cell tissue matrix for repair. The patient also developed severe mitral regurgitation suggesting infarct to the left coronary system during resection, subsequently receiving a mechanical mitral valve and a saphenous vein bypass graft...
2016: Clinical Medicine Insights. Case Reports
https://www.readbyqxmd.com/read/27847072/iatrogenic-lesion-of-an-anomalous-circumflex-coronary-artery-during-mitral-surgery
#2
Ana Lopez-Marco, Aidil Syed, Tom Combellack, Dheeraj Mehta
A patient with anomalous coronary circulation presented with non-ST segment elevation myocardial infarction and ischemic mitral regurgitation and underwent mitral valve repair and coronary revascularization. An unexpected tear occurred in the roof of the left atrium, and its subsequent repair caused iatrogenic damage of the anomalous circumflex artery on its abnormal course requiring an extra graft. Early suspicion of the iatrogenic damage to the anomalous artery was the key for good and complete recovery in this case...
December 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27815962/the-effects-of-type-1-diabetes-mellitus-on-cardiac-functions-in-children-evaluation-by-conventional-and-tissue-doppler-echocardiography
#3
Osman Ozdemir, Adem Yasin Koksoy, Ayse Derya Bulus, Nesibe Andiran, Elif Yagli
BACKGROUND: Several studies have pointed out the existence of cardiac dysfunction in patients with type 1 diabetes mellitus (DM) even in the absence of ischemic, valvular, or hypertensive heart disease. The present study evaluated cardiac dysfunction and the relationship between severity of disease and degree of cardiac dysfunction in children with type 1 DM. METHODS: In this prospective study, 31 patients with type 1 DM and 33 sex- and age-matched healthy children were evaluated with conventional echocardiography and tissue Doppler echocardiography (TDE)...
December 1, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27811121/automatic-valve-plane-localization-in-myocardial-perfusion-spect-ct-by-machine-learning-anatomical-and-clinical-validation
#4
Julian Betancur, Mathieu Rubeaux, Tobias Fuchs, Yuka Otaki, Yoav Arnson, Leandro Slipczuk, Dominik Benz, Guido Germano, Damini Dey, Chih-Jen Lin, Daniel Berman, Philipp Kaufmann, Piotr Slomka
: Precise definition of the mitral valve plane (VP) during segmentation of the left ventricle (LV) for single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) quantification often requires manual adjustment, which affects quantification of perfusion. We developed a machine learning approach using support vector machines (SVM) for automatic VP placement. METHODS: 392 consecutive patients undergoing fast SPECT MPI (99m)Tc-tetrofosmin stress (5 min, 300-350 MBq)/rest (5 min, 750-1050 MBq) attenuation corrected (AC) by computed tomography (CT) and same‑day coronary CT angiography (CCTA), including 48 patients with invasive angiography (ICA) and no known coronary artery disease, were studied...
November 3, 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27803828/a-historic-case-of-cardiac-surgery-in-pregnancy
#5
Said Benlamkaddem, Adnane Berdai, Smael Labib, Mustapha Harandou
Background. Heart disease is the leading cause of nonobstetric mortality in pregnant women. Because of high risk, medical management represents the first line of treatment. However, when medical treatment fails, cardiac surgery becomes necessary. Case Presentation. A 27-year-old female who underwent successfully cardiac surgery three times within 3 years. At the first time, she had an aortic valve replacement at 25 weeks of gestation after an infectious endocarditis complicated with an ischemic stroke. At 39 weeks of gestation, she had delivered, vaginally, a healthy baby boy weighing 2800 g...
2016: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27777294/impact-of-left-ventricular-to-mitral-valve-ring-mismatch-on-recurrent-ischemic-mitral-regurgitation-after-ring-annuloplasty
#6
Romain Capoulade, Xin Zeng, Jessica R Overbey, Gorav Ailawadi, John H Alexander, Deborah Ascheim, Michael Bowdish, Annetine C Gelijns, Paul Grayburn, Irving L Kron, Robert A Levine, Michael J Mack, Serguei Melnitchouk, Robert E Michler, John C Mullen, Patrick O'Gara, Michael K Parides, Peter Smith, Pierre Voisine, Judy Hung
BACKGROUND: In ischemic mitral regurgitation (IMR), ring annuloplasty is associated with a significant rate of recurrent MR. Ring size is based on intertrigonal distance without consideration of left ventricular (LV) size. However, LV size is an important determinant of mitral valve (MV) leaflet tethering before and after repair. We aimed to determine whether LV-MV ring mismatch (mismatch of LV size relative to ring size) is associated with recurrent MR in patients with IMR after restrictive ring annuloplasty...
October 25, 2016: Circulation
https://www.readbyqxmd.com/read/27773578/is-subvalvular-repair-worthwhile-in-severe-ischemic-mitral-regurgitation-subanalysis-of-the-papillary-muscle-approximation-trial
#7
Francesco Nappi, Cristiano Spadaccio, Antonio Nenna, Mario Lusini, Massimiliano Fraldi, Christophe Acar, Massimo Chello
OBJECTIVE: The symmetry of mitral valve tethering and regional left ventricle wall dysfunction are reported to play a fundamental role in the outcomes and long-term durability of surgical repair in ischemic mitral regurgitation (IMR). We recently demonstrated in a randomized clinical trial (the Papillary Muscle Approximation trial) the superiority of papillary muscle approximation (PMA) in combination with standard restrictive annuloplasty (RA) in severe IMR over annuloplasty alone in terms of adverse left ventricular remodeling and mitral regurgitation (MR) recurrence...
September 24, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27750208/cd45-expression-in-mitral-valve-endothelial-cells-after-myocardial-infarction
#8
Joyce Bischoff, Guillem Casanovas, Jill Wylie-Sears, Dae-Hee Kim, Philipp Bartko, J Guerrero, Jacob Dal-Bianco, Jonathan Beaudoin, Michael Garcia, Suzanne Sullivan, Margo Seybolt, Brittan Morris, Joshua Keegan, Whitney Irvin, Elena Aikawa, Robert Levine
RATIONALE: Ischemic mitral regurgitation (IMR), a complication after myocardial infarction (MI), induces adaptive mitral valve (MV) responses that may be initially beneficial, but eventually lead to leaflet fibrosis and MV dysfunction. We sought to examine the MV endothelial response and its potential contribution to IMR. OBJECTIVE: Endothelial, interstitial and hematopoietic cells in MVs from post-MI sheep were quantified. MV endothelial CD45, found post-MI, was analyzed in vitro...
October 6, 2016: Circulation Research
https://www.readbyqxmd.com/read/27720263/characteristics-and-outcomes-of-patients-with-postoperative-cardiovascular-pseudoaneurysms
#9
Michael Chenier, Krishna K Patel, Lars G Svensson, Jose Navia, Joseph F Sabik, L Leonardo Rodriguez, Richard A Grimm, Brian P Griffin, Milind Y Desai
BACKGROUND: Data regarding long-term outcomes in cardiovascular pseudoaneurysms are sparse. In patients with prior cardiovascular surgery, we sought to assess characteristics and outcomes in patients with cardiovascular pseudoaneurysms (excluding ischemic left ventricular pseudoaneurysms). METHODS: We included 114 patients (mean age, 57 ± 16 years; 70% were men) with prior cardiovascular surgery who presented with paravalvular (n = 71, 59 aortic and 12 mitral valve) and ascending aortic (n = 43) pseudoaneurysms (27% with systemic infection)...
September 22, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27720201/undersized-mitral-annuloplasty-increases-strain-in-the-proximal-lateral-left-ventricular-wall
#10
Joe Luis Pantoja, Ashley E Morgan, Eugene A Grossi, Morten O Jensen, Jonathan W Weinsaft, Robert A Levine, Liang Ge, Mark B Ratcliffe
BACKGROUND: Recurrence of mitral regurgitation (MR) after undersized mitral annuloplasty (MA) for ischemic MR is as high as 60%, with the recurrence rate likely due to continued dilation of the left ventricle (LV). To better understand the causes of recurrent MR, we studied the effect of undersized MA on strain in the LV wall. We hypothesize that the acute change in ventricular shape induced by MA will cause increased strain in regions nearest the mitral valve. METHODS: Finite element models were previously reported, based on cardiac magnetic resonance images of 5 sheep with mild to moderate ischemic MR...
October 5, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27703088/rheumatic-mitral-valve-disease-is-associated-with-worse-outcomes-in-stroke-a-thailand-national-database-study
#11
Adrian D Wood, Gurdeep S Mannu, Allan B Clark, Somsak Tiamkao, Kannikar Kongbunkiat, Joao H Bettencourt-Silva, Kittisak Sawanyawisuth, Narongrit Kasemsap, Raphae S Barlas, Mamas Mamas, Phyo Kyaw Myint
BACKGROUND AND PURPOSE: Rheumatic valvular heart disease is associated with the increased risk of cerebrovascular events, although there are limited data on the prognosis of patients with rheumatic mitral valve disease (RMVD) after stroke. METHODS: We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored...
November 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27671215/short-and-medium-term-effects-of-combined-mitral-valve-surgery-and-coronary-artery-bypass-grafting-versus-coronary-artery-bypass-grafting-alone-for-patients-with-moderate-ischemic-mitral-regurgitation-a-meta-analysis
#12
Liangshan Wang, Bo Li, Changcheng Liu, Tianhua Rong, Yang Yu, Chengxiong Gu
OBJECTIVE: To investigate the short- and medium-term effects of combined mitral valve surgery (MVS) and coronary artery bypass grafting (CABG) versus CABG alone for patients with moderate ischemic mitral regurgitation (IMR). DESIGN: Meta-analysis of 4 randomized controlled trials (RCTs) and 5 observational studies. SETTING: Hospitals that perform cardiac surgery. PARTICIPANTS: The study included 1,256 cardiac surgery patients from 4 RCTs and 5 observational studies...
December 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27666784/when-should-the-mitral-valve-be-repaired-or-replaced-in-patients-with-ischemic-mitral-regurgitation
#13
Vincent Chan, Olivier Levac-Martinho, Benjamin Sohmer, Elsayed Elmistekawy, Marc Ruel, Thierry G Mesana
BACKGROUND: Data comparing outcomes after repair versus replacement of chronic ischemic mitral regurgitation (MR) is evolving. Recent data suggest that repair is associated with recurrent MR, but not survival, when compared with replacement. However, it remains unclear when either surgical strategy should be applied based on preoperative mitral valve anatomy. METHODS: Between 2001 and 2013, 161 patients underwent repair or replacement of chronic ischemic MR. The mean age of these patients was 68...
September 22, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27648320/flair-hyperintense-vessel-sign-of-both-mcas-with-severe-heart-failure
#14
Donghee Kim, Seung-Yul Lee, Kwon-Duk Seo
Introduction. Fluid-attenuated inversion recovery hyperintense vessels (FHVs) can be seen in patients with occlusion or severe stenosis of the cerebral arteries. FHVs are known to reflect stagnant or slow blood flow within the cerebral artery. Case Report. A 75-year-old woman presented with suddenly developed gait disturbance. She had a history of hypertension, heart failure, and dementia. Brain MRI demonstrated FHVs within both middle cerebral arteries (MCAs). However, there was no acute ischemic lesion and severe stenosis or occlusion of the cerebral arteries...
2016: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/27612148/anterior-mitral-leaflet-augmentation-for-ischemic-mitral-regurgitation-performed-via-a-right-thoracotomy-approach
#15
Christos G Mihos, Andres M Pineda, Sofia A Horvath, Orlando Santana
Ischemic mitral regurgitation (MR) after myocardial infarction is associated with poor long-term survival, and the optimal treatment strategy remains debated. The most common repair technique used is a restrictive annuloplasty. However, up to 15% to 30% of patients experience recurrent MR owing to progressive left ventricular remodeling and geometric distortion of the mitral valve apparatus. Anterior mitral leaflet augmentation using a pericardial patch, in combination with a true-sized mitral annuloplasty, has been proposed as an adjunctive technique to increase the durability of valve repair for ischemic MR...
July 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27585461/repair-or-replace-ischemic-mitral-regurgitation-during-coronary-artery-bypass-grafting-a-meta-analysis
#16
Yushu Wang, Xiuli Shi, Meiqin Wen, Yucheng Chen, Qing Zhang
BACKGROUND: No agreement has been reached for the best surgical treatment for patients with chronic ischemic mitral regurgitation (IMR) undergoing coronary artery bypass grafting (CABG). Our objective was to meta-analyze the clinical outcomes of repair and replacement. METHODS: A computerized search was performed using Pubmed, Embase, Ovid medline and Cochrane Library. The search terms "ischemic or ischaemic" and "mitral valve" and "repair or replacement or annuloplasty" and "coronary artery bypass grafting" were entered as MeSH terms and keywords...
September 1, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27582769/percutaneous-coronary-intervention-for-acute-myocardial-infarction-with-mitral-regurgitation
#17
Yan Tu, Qing-Chun Zeng, Ying Huang, Jian-Yong Li
Ischemic mitral regurgitation (IMR) is a common complication of acute myocardial infarction (AMI). Current evidences suggest that revascularization of the culprit vessels with percutaneous coronary artery intervention (PCI) or coronary artery bypass grafting can be beneficial for relieving IMR. A 2.5-year follow-up data of a 61-year-old male patient with ST-segment elevation AMI complicated with IMR showed that mitral regurgitation area increased five days after PCI, and decreased to lower steady level three months after PCI...
September 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27556316/mitral-valve-prolapse-in-pregnancy
#18
Shi-Min Yuan, Song-Li Yan
Mitral valve prolapse is a benign condition. Mitral regurgitation is only complicated in patients with severe mitral valve prolapse. Women with mitral valve prolapse in the absence of other cardiovascular disorders tolerate pregnancy well and do not develop remarkable cardiac complications. Nevertheless, serious complications of mitral valve prolapse, including arrhythmia, infective endocarditis and cerebral ischemic events, can be present in pregnancy. Debates remain with regard to the use of prophylactic antibiotics and β-blockers in the pregnant women with mitral valve prolapse...
April 2016: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27554386/spontaneous-intramural-hematoma-of-the-colon
#19
Samuel Fernandes, Ana Rita Gonçalves, Luís Araújo Correia
A 73-year-old man was admitted to our clinic with sudden left quadrant abdominal pain and hematochezia. There was no history of trauma. He denied other symptoms or taking off-the-counter medication. His medical history was relevant for ischemic and aortic-mitral valve disease with prosthetic valves for which he was medicated with aspirin and warfarin. On physical examination the patient presented normal vital signs with tenderness on palpation of the left side of the abdomen. Laboratory tests revealed moderate anemia (10...
August 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27530639/the-value-of-preoperative-3-dimensional-over-2-dimensional-valve-analysis-in-predicting-recurrent-ischemic-mitral-regurgitation-after-mitral-annuloplasty
#20
Inez J Wijdh-den Hamer, Wobbe Bouma, Eric K Lai, Melissa M Levack, Eric K Shang, Alison M Pouch, Thomas J Eperjesi, Theodore J Plappert, Paul A Yushkevich, Judy Hung, Massimo A Mariani, Kamal R Khabbaz, Thomas G Gleason, Feroze Mahmood, Michael A Acker, Y Joseph Woo, Albert T Cheung, Matthew J Gillespie, Benjamin M Jackson, Joseph H Gorman, Robert C Gorman
OBJECTIVES: Repair for ischemic mitral regurgitation with undersized annuloplasty is characterized by high recurrence rates. We sought to determine the value of pre-repair 3-dimensional echocardiography over 2-dimensional echocardiography in predicting recurrence at 6 months. METHODS: Intraoperative transesophageal 2-dimensional echocardiography and 3-dimensional echocardiography were performed in 50 patients undergoing undersized annuloplasty for ischemic mitral regurgitation...
September 2016: Journal of Thoracic and Cardiovascular Surgery
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