keyword
Keywords (network or connectivity) AND ...

(network or connectivity) AND (structural gray matter network OR cortical thickness)

https://read.qxmd.com/read/37520126/alterations-of-gut-microbiota-are-associated-with-brain-structural-changes-in-the-spectrum-of-alzheimer-s-disease-the-silcode-study-in-hainan-cohort
#21
JOURNAL ARTICLE
Beiqi He, Can Sheng, Xianfeng Yu, Liang Zhang, Feng Chen, Ying Han
BACKGROUND: The correlation between gut microbiota and Alzheimer's disease (AD) is increasingly being recognized by clinicians. However, knowledge about the gut-brain-cognition interaction remains largely unknown. METHODS: One hundred and twenty-seven participants, including 35 normal controls (NCs), 62 with subjective cognitive decline (SCD), and 30 with cognitive impairment (CI), were included in this study. The participants underwent neuropsychological assessments and fecal microbiota analysis through 16S ribosomal RNA (rRNA) Illumina Miseq sequencing technique...
2023: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/37480705/structural-brain-networks-in-schizophrenia-based-on-nonnegative-matrix-factorization
#22
JOURNAL ARTICLE
Rongjie Dai, Christina J Herold, Xingsong Wang, Li Kong, Johannes Schröder
Schizophrenia is a severe mental disease with significant morphometric reductions in gray matter volume and cortical thickness in a variety of brain regions. However, most studies only focused on the voxel level alterations in specific cerebral regions and ignored the spatial relationship between voxels. In the present study, we used a novel, data-driven technique-nonnegative matrix factorization (NMF) to group voxels with similar information into a network, and studied the structural covariance at the network level in schizophrenia...
July 20, 2023: Psychiatry Research. Neuroimaging
https://read.qxmd.com/read/37442456/differential-effects-of-generalized-anxiety-and-separation-anxiety-on-brain-structural-development-during-adolescence
#23
JOURNAL ARTICLE
Zheyi Zhou, Yiman Li, Yuqi Zhang, Jing Liu, Hui Ai, Mingfang Liu, Jianyin Qiu, Yue-Jia Luo, Pengfei Xu
Excessive anxiety is highly prevalent during childhood and adolescence, with detrimental effects on somatic and mental health, and quality of life. Although structural abnormalities in the brain have been found in people with anxiety disorders, whether anxiety affects the brain development of children and adolescents remains unknown. Here, we applied a multivariate approach to two single-site MRI datasets consisting of 733 and 775 participants aged 5-18 years. Using linear support vector regression and cross-validation, brain age is estimated by predicting the chronological age from the features that combine cortical thickness and surface area of 68 brain regions...
July 11, 2023: Journal of Affective Disorders
https://read.qxmd.com/read/37381581/disrupted-brain-gray-matter-connectome-in-social-anxiety-disorder-a-novel-individualized-structural-covariance-network-analysis
#24
JOURNAL ARTICLE
Xun Zhang, Han Lai, Qingyuan Li, Xun Yang, Nanfang Pan, Min He, Graham J Kemp, Song Wang, Qiyong Gong
Phenotyping approaches grounded in structural network science can offer insights into the neurobiological substrates of psychiatric diseases, but this remains to be clarified at the individual level in social anxiety disorder (SAD). Using a recently developed approach combining probability density estimation and Kullback-Leibler divergence, we constructed single-subject structural covariance networks (SCNs) based on multivariate morphometry (cortical thickness, surface area, curvature, and volume) and quantified their global/nodal network properties using graph-theoretical analysis...
June 28, 2023: Cerebral Cortex
https://read.qxmd.com/read/37354489/linking-polygenic-risk-of-schizophrenia-to-variation-in-magnetic-resonance-imaging-brain-measures-a-comprehensive-systematic-review
#25
JOURNAL ARTICLE
Hadis Jameei, Divyangana Rakesh, Andrew Zalesky, Murray J Cairns, William R Reay, Naomi R Wray, Maria A Di Biase
BACKGROUND AND HYPOTHESIS: Schizophrenia is highly heritable, with a polygenic effect of many genes conferring risk. Evidence on whether cumulative risk also predicts alterations in brain morphology and function is inconsistent. This systematic review examined evidence for schizophrenia polygenic risk score (sczPRS) associations with commonly used magnetic resonance imaging (MRI) measures. We expected consistent evidence to emerge for significant sczPRS associations with variation in structure and function, specifically in frontal, temporal, and insula cortices that are commonly implicated in schizophrenia pathophysiology...
June 24, 2023: Schizophrenia Bulletin
https://read.qxmd.com/read/37103603/the-association-between-white-matter-tract-structural-connectivity-and-information-processing-speed-in-relapsing-remitting-multiple-sclerosis
#26
JOURNAL ARTICLE
Magdalena Chylińska, Bartosz Karaszewski, Jakub Komendziński, Adam Wyszomirski, Marek Hałas, Edyta Szurowska, Agnieszka Sabisz
BACKGROUND: Information processing speed (IPS) deterioration is common in relapsing-remitting multiple sclerosis (RRMS) patients [1] and might severely affect quality of life and occupational activity. However, understanding of its neural substrate is not fully elucidated. We aimed to investigate the associations between MRI-derived metrics of neuroanatomical structures, including the tracts, and IPS. METHODS: Symbol Digit Modalities Test (SDMT), Paced Auditory Serial Addition Test (PASAT), and Color Trails Test (CTT) were used to evaluate IPS in 73 RRMS consecutive patients, all undergoing only interferon beta (IFN-β) therapy during the study...
April 27, 2023: Neurological Sciences
https://read.qxmd.com/read/37074446/superficial-white-matter-across-development-young-adulthood-and-aging-volume-thickness-and-relationship-with-cortical-features
#27
JOURNAL ARTICLE
Kurt G Schilling, Derek Archer, Francois Rheault, Ilwoo Lyu, Yuankai Huo, Leon Y Cai, Silvia A Bunge, Kevin S Weiner, John C Gore, Adam W Anderson, Bennett A Landman
Superficial white matter (SWM) represents a significantly understudied part of the human brain, despite comprising a large portion of brain volume and making up a majority of cortico-cortical white matter connections. Using multiple, high-quality datasets with large sample sizes (N = 2421, age range 5-100) in combination with methodological advances in tractography, we quantified features of SWM volume and thickness across the brain and across development, young adulthood, and aging. We had four primary aims: (1) characterize SWM thickness across brain regions (2) describe associations between SWM volume and age (3) describe associations between SWM thickness and age, and (4) quantify relationships between SWM thickness and cortical features...
May 2023: Brain Structure & Function
https://read.qxmd.com/read/36967830/white-matter-and-gray-matter-changes-related-to-cognition-in-community-populations
#28
JOURNAL ARTICLE
Wen-Xin Li, Jing Yuan, Fei Han, Li-Xin Zhou, Jun Ni, Ming Yao, Shu-Yang Zhang, Zheng-Yu Jin, Li-Ying Cui, Fei-Fei Zhai, Yi-Cheng Zhu
OBJECTIVE: Further studies are needed to improve the understanding of the pathological process underlying cognitive impairments. The purpose of this study is to investigate the global and topographic changes of white matter integrity and cortical structure related to cognitive impairments in a community-based population. METHODS: A cross-sectional analysis was performed based on 995 subjects (aged 56.8 ± 9.1 years, 34.8% males) from the Shunyi study, a community-dwelling cohort...
2023: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/36965364/analyzing-structural-and-functional-brain-changes-related-to-an-integrative-cognitive-remediation-program-for-schizophrenia-a-randomized-controlled-trial
#29
JOURNAL ARTICLE
Agurne Sampedro, Naroa Ibarretxe-Bilbao, Javier Peña, Alberto Cabrera-Zubizarreta, Pedro Sánchez, Ainara Gómez-Gastiasoro, Nagore Iriarte-Yoller, Cristóbal Pavón, Mikel Tous-Espelosin, Natalia Ojeda
Cognitive remediation has been shown to improve cognition in schizophrenia, but little is known about the specific functional and structural brain changes related to the implementation of an integrative cognitive remediation program. This study analyzed the functional and structural brain changes identified after implementing an integrative cognitive remediation program, REHACOP, in schizophrenia. The program combined cognitive remediation, social cognitive training, and functional and social skills training...
March 23, 2023: Schizophrenia Research
https://read.qxmd.com/read/36942514/functional-and-structural-alterations-of-dorsal-attention-network-in-preclinical-and-early-stage-alzheimer-s-disease
#30
JOURNAL ARTICLE
Huimin Wu, Yu Song, Xinyi Yang, Shanshan Chen, Honglin Ge, Zheng Yan, Wenzhang Qi, Qianqian Yuan, Xuhong Liang, Xingjian Lin, Jiu Chen
OBJECTIVES: Subjective cognitive decline (SCD) and amnestic mild cognitive impairment (aMCI) are known as the preclinical and early stage of Alzheimer's disease (AD). The dorsal attention network (DAN) is mainly responsible for the "top-down" attention process. However, previous studies mainly focused on single functional modality and limited structure. This study aimed to investigate the multimodal alterations of DAN in SCD and aMCI to assess their diagnostic value in preclinical and early-stage AD...
March 21, 2023: CNS Neuroscience & Therapeutics
https://read.qxmd.com/read/36896988/a-machine-learning-derived-neuroanatomical-pattern-predicts-delayed-reward-discounting-in-the-human-connectome-project-young-adult-sample
#31
JOURNAL ARTICLE
Hui Xu, James MacKillop, Max M Owens
Delayed reward discounting (DRD) is defined as the extent to which person favors smaller rewards that are immediately available over larger rewards available in the future. Higher levels of DRD have been identified in individuals with a wide range of clinical disorders. Although there have been studies adopting larger samples and using only gray matter volume to characterize the neuroanatomical correlates of DRD, it is still unclear whether previously identified relationships are generalizable (out-of-sample) and how cortical thickness and cortical surface area contribute to DRD...
March 10, 2023: Journal of Neuroscience Research
https://read.qxmd.com/read/36860499/functional-connectivity-and-gray-matter-deficits-within-the-auditory-attention-circuit-in-first-episode-psychosis
#32
JOURNAL ARTICLE
Mark T Curtis, Alfredo L Sklar, Brian A Coffman, Dean F Salisbury
BACKGROUND: Selective attention deficits in first episode of psychosis (FEP) can be indexed by impaired attentional modulation of auditory M100. It is unknown if the pathophysiology underlying this deficit is restricted to auditory cortex or involves a distributed attention network. We examined the auditory attention network in FEP. METHODS: MEG was recorded from 27 FEP and 31 matched healthy controls (HC) while alternately ignoring or attending tones. A whole-brain analysis of MEG source activity during auditory M100 identified non-auditory areas with increased activity...
2023: Frontiers in Psychiatry
https://read.qxmd.com/read/36808599/the-characteristics-of-brain-structural-remodeling-in-patients-with-unilateral-vestibular-schwannoma
#33
JOURNAL ARTICLE
Hanlu Tang, Zhixu Bie, Bo Wang, Zhijun Yang, Peng Li, Xingchao Wang, Pinan Liu
PURPOSE: Brain structural remodeling alters related brain function. However, few studies have assessed morphological alterations of unilateral vestibular schwannoma (VS) patients. Therefore, this study examined the characteristics of brain structural remodeling in unilateral VS patients. METHODS: We recruited 39 patients with unilateral VS (19 left, 20 right) and 24 matched normal controls (NCs). We obtained brain structural imaging data using 3T T1-weighted anatomical and diffusion tensor imaging scans...
February 20, 2023: Journal of Neuro-oncology
https://read.qxmd.com/read/36769662/neuroimaging-studies-of-the-neural-correlates-of-heart-rate-variability-a-systematic-review
#34
REVIEW
Patrycja S Matusik, Chuwen Zhong, Paweł T Matusik, Omar Alomar, Phyllis K Stein
Direct and indirect links between brain regions and cardiac function have been reported. We performed a systematic literature review to summarize current knowledge regarding the associations of heart rate variability (HRV) and brain region morphology, activity and connectivity involved in autonomic control at rest in healthy subjects. Both positive and negative correlations of cortical thickness and gray matter volumes of brain structures with HRV were observed. The strongest were found for a cluster located within the cingulate cortex...
January 28, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/36752489/structural-and-functional-brain-changes-in-acute-takotsubo-syndrome
#35
JOURNAL ARTICLE
Hilal Khan, David T Gamble, Amelia Rudd, Alice M Mezincescu, Hassan Abbas, Awsan Noman, Andrew Stewart, Graham Horgan, Rajeev Krishnadas, Christopher Williams, Gordon D Waiter, Dana K Dawson
BACKGROUND: Takotsubo syndrome mimics an acute myocardial infarction, typically in the aftermath of mental or physical stress. OBJECTIVES: The mechanism by which emotional processing in the context of stress leads to significant cardiac injury is poorly understood, so a full exploration of brain structure and function in takotsubo syndrome patients merits investigation. METHODS: Twenty-five acute (<5 days) takotsubo patients and 25 control subjects were recruited into this observational cross-sectional study...
November 30, 2022: JACC. Heart Failure
https://read.qxmd.com/read/36694086/consistent-differences-in-brain-structure-and-functional-connectivity-in-high-altitude-native-tibetans-and-immigrants
#36
JOURNAL ARTICLE
Xinjuan Zhang, Weiwei Xie, Wenrui Du, Yanqiu Liu, Jianzhong Lin, Wu Yin, Lihui Yang, Fengjuan Yuan, Ran Zhang, Haipeng Liu, Hailin Ma, Jiaxing Zhang
It has been well-established that high-altitude (HA) environments affect the human brain; however, the differences in brain structural and functional networks between HA natives and acclimatized immigrants have not been well clarified. In this study, native HA Tibetans were recruited for comparison with Han immigrants (average of 2.3 ± 0.3 years at HA), with lowland residents recruited as controls. Cortical gray matter volume, thickness, and functional connectivity were investigated using magnetic resonance imaging data...
January 25, 2023: Brain Imaging and Behavior
https://read.qxmd.com/read/36575854/brain-structure-and-allelic-associations-in-alzheimer-s-disease
#37
JOURNAL ARTICLE
Seok Woo Moon, Lu Zhao, William Matloff, Sam Hobel, Ryan Berger, Daehong Kwon, Jaebum Kim, Arthur W Toga, Ivo D Dinov
BACKGROUND: Alzheimer's disease (AD), the most prevalent form of dementia, affects 6.5 million Americans and over 50 million people globally. Clinical, genetic, and phenotypic studies of dementia provide some insights of the observed progressive neurodegenerative processes, however, the mechanisms underlying AD onset remain enigmatic. AIMS: This paper examines late-onset dementia-related cognitive impairment utilizing neuroimaging-genetics biomarker associations...
April 2023: CNS Neuroscience & Therapeutics
https://read.qxmd.com/read/36544100/cortical-thickness-analysis-in-temporal-lobe-epilepsy-using-fully-bayesian-spectral-method-in-magnetic-resonance-imaging
#38
JOURNAL ARTICLE
Iman Sarbisheh, Leili Tapak, Alireza Fallahi, Javad Fardmal, Majid Sadeghifar, MohammadReza Nazemzadeh, Jafar Mehvari Habibabadi
BACKGROUND: Temporal lobe epilepsy (TLE) is the most common type of epilepsy associated with changes in the cerebral cortex throughout the brain. Magnetic resonance imaging (MRI) is widely used for detecting such anomalies; nevertheless, it produces spatially correlated data that cannot be considered by the usual statistical models. This study aimed to compare cortical thicknesses between patients with TLE and healthy controls by considering the spatial dependencies across different regions of the cerebral cortex in MRI...
December 21, 2022: BMC Medical Imaging
https://read.qxmd.com/read/36471581/aberrant-gray-matter-structure-in-neurosyphilis-without-conventional-mri-abnormality-a-pilot-study-with-voxel-and-surface-based-morphology
#39
JOURNAL ARTICLE
Zi-Ning Lu, Sheng-Juan Yao, Yu Cao, Yue Cheng, Xiao-Tian Li, Hong-Shuai Guo, Xiao-Dong Zhang
BACKGROUND: The underlying mechanism of neurosyphilis was not fully understood. PURPOSE: To assess gray matter (GM) microstructure in patients with early-stage neurosyphilis without overt conventional magnetic resonance imaging (MRI) abnormality using voxel-based morphometry (VBM) and surface-based morphometry (SBM) analyses. MATERIAL AND METHODS: Three-dimensional high-resolution T1-weighted imaging data from 19 individuals with neurosyphilis and 19 healthy controls were analyzed...
December 5, 2022: Acta Radiologica
https://read.qxmd.com/read/36455022/major-gender-differences-in-relations-between-life-stressor-frequency-and-gray-matter-in-adolescence-and-emerging-adulthood
#40
JOURNAL ARTICLE
Alyssa N Fassett-Carman, Harry Smolker, Benjamin L Hankin, Hannah R Snyder, Marie T Banich
Adolescence and emerging adulthood is likely a sensitive period for the neural effects of stress due to increasing life stress, onset of stress-related disorders, and continued gray matter (GM) development. In adults, stress is associated with GM differences in the medial prefrontal cortex (mPFC), hippocampus, and amygdala, but little is known about these relations, and whether they differ by gender, during adolescence and emerging adulthood. Further, it is unknown whether dependent (self-generated) and independent (fateful) stressors have distinct associations with GM, as each have distinct relations with internalizing psychopathology...
December 1, 2022: Developmental Psychology
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