Kurt G Schilling, Derek Archer, Francois Rheault, Ilwoo Lyu, Yuankai Huo, Leon Y Cai, Silvia A Bunge, Kevin S Weiner, John C Gore, Adam W Anderson, Bennett A Landman
Superficial white matter (SWM) represents a significantly understudied part of the human brain, despite comprising a large portion of brain volume and making up a majority of cortico-cortical white matter connections. Using multiple, high-quality datasets with large sample sizes (N = 2421, age range 5-100) in combination with methodological advances in tractography, we quantified features of SWM volume and thickness across the brain and across development, young adulthood, and aging. We had four primary aims: (1) characterize SWM thickness across brain regions (2) describe associations between SWM volume and age (3) describe associations between SWM thickness and age, and (4) quantify relationships between SWM thickness and cortical features...
May 2023: Brain Structure & Function