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https://www.readbyqxmd.com/read/28454401/safety-and-effectiveness-of-localized-lung-resection-combined-with-neoadjuvant-chemotherapy-in-the-treatment-of-stage-i-ii-non-small-cell-lung-cancer
#1
Bing Zhu, Jianru Yang, Pei Zhang, Lin Shen, Xiaolong Li, Jing Li
This study was conducted to evaluate the safety and effectiveness of localized lung resection combined with neoadjuvant chemotherapy in the treatment of stage I-II non-small cell lung cancer (NSCLC). A total of 88 patients, who were admitted to our hospital for first diagnosis and treatment, were selected. The patients were divided into control group (n=40 cases) and observation group (n=48 cases) according to the last digit of the admission number. The control group was treated with minimally invasive localized lung resection by thoracoscope...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454281/current-status-of-the-prognostic-molecular-biomarkers-in-breast-cancer-a-systematic-review
#2
Goro Kutomi, Toru Mizuguchi, Fukino Satomi, Hideki Maeda, Hiroaki Shima, Yasutoshi Kimura, Koichi Hirata
Biomarkers that facilitate the prediction of breast cancer prognosis can improve the quality of life in patients during the long period of illness and treatment. Particularly in recent years, with the advent of a more exhaustive analysis of genetic information and gene products, the molecular mechanisms at play during breast cancer have gradually become clearer. In the present study, a systematic review of the literature between 2009 and 2014 was conducted by searching for the keywords 'breast cancer', 'biomarkers', 'diagnosis', 'prognosis' and 'drug response' to clarify the present state of knowledge regarding biomarkers...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454079/burnout-and-its-association-with-extracurricular-activities-among-medical-students-in-saudi-arabia
#3
Sami A Almalki, Abdullah I Almojali, Ali S Alothman, Emad M Masuadi, Meshal K Alaqeel
Objectives: To assess levels of burnout in medical students, and to explore the influence of extracurricular activities on burnout at a medical school in Saudi Arabia. Methods: This cross-sectional study was conducted with first to fourth year medical students at King Saud bin Abdulaziz University for Health Sciences (KSAU-HS) in Riyadh, Saudi Arabia. Socio-demographic, burnout level (the Maslach Burnout Inventory-Student Survey, MBI-SS) and participation in extracurricular activities data were collected using a self-administered questionnaire...
April 26, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28454068/biochar-based-water-treatment-systems-as-a-potential-low-cost-and-sustainable-technology-for-clean-water-provision
#4
REVIEW
Willis Gwenzi, Nhamo Chaukura, Chicgoua Noubactep, Fungai N D Mukome
Approximately 600 million people lack access to safe drinking water, hence achieving Sustainable Development Goal 6 (Ensure availability and sustainable management of water and sanitation for all by 2030) calls for rapid translation of recent research into practical and frugal solutions within the remaining 13 years. Biochars, with excellent capacity to remove several contaminants from aqueous solutions, constitute an untapped technology for drinking water treatment. Biochar water treatment has several potential merits compared to existing low-cost methods (i...
April 25, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28454025/review-and-analysis-of-strengths-and-weaknesses-of-agro-ecosystem-models-for-simulating-c-and-n-fluxes
#5
REVIEW
Lorenzo Brilli, Luca Bechini, Marco Bindi, Marco Carozzi, Daniele Cavalli, Richard Conant, Cristopher D Dorich, Luca Doro, Fiona Ehrhardt, Roberta Farina, Roberto Ferrise, Nuala Fitton, Rosa Francaviglia, Peter Grace, Ileana Iocola, Katja Klumpp, Joël Léonard, Raphaël Martin, Raia Silvia Massad, Sylvie Recous, Giovanna Seddaiu, Joanna Sharp, Pete Smith, Ward N Smith, Jean-Francois Soussana, Gianni Bellocchi
Biogeochemical simulation models are important tools for describing and quantifying the contribution of agricultural systems to C sequestration and GHG source/sink status. The abundance of simulation tools developed over recent decades, however, creates a difficulty because predictions from different models show large variability. Discrepancies between the conclusions of different modelling studies are often ascribed to differences in the physical and biogeochemical processes incorporated in equations of C and N cycles and their interactions...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28454015/air-pollution-characteristics-and-health-risks-in-henan-province-china
#6
Fuzhen Shen, Xinlei Ge, Jianlin Hu, Dongyang Nie, Li Tian, Mindong Chen
Events of severe air pollution occurred frequently in China recently, thus understanding of the air pollution characteristics and its health risks is very important. In this work, we analyzed a two-year dataset (March 2014 - February 2016) including daily concentrations of six criteria pollutants (PM2.5, PM10, CO, SO2, NO2, and O3) from 18 cities in Henan province. Results reveal the serious air pollution status in Henan province, especially the northern part, and Zhengzhou is the city with the worst air quality...
April 25, 2017: Environmental Research
https://www.readbyqxmd.com/read/28453958/the-novel-technique-of-post-hysterectomy-vaginal-vault-prolapse-repair-apical-sling-and-neocervix-formation
#7
Dmitry Shkarupa, Nikita Kubin, Ekaterina Shapovalova, Anastasiya Zaytseva, Alexey Pisarev, Olga Staroseltseva
OBJECTIVE: We primarily aimed to evaluate the effectiveness of the novel technique: bilateral sacrospinous fixation by monofilament polypropylene apical sling combined with "neocervix" formation in surgical treatment of post - hysterectomy vaginal vault prolapse. The secondary objective was to estimate the impact of the surgery on voiding function and quality of life. STUDY DESIGN: This prospective study involved 61 women suffering from post-hysterectomy prolapse...
April 23, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28453826/unplanned-readmissions-within-30-days-after-discharge-improving-quality-through-easy-prediction
#8
Francesca Casalini, Susanna Salvetti, Silvia Memmini, Elena Lucaccini, Gabriele Massimetti, Pier Luigi Lopalco, Gaetano Pierpaolo Privitera
Objective: To propose an easy predictive model for the risk of rehospitalization, built from hospital administrative data, in order to prevent repeated admissions and to improve transitional care. Design: Retrospective cohort study. Setting: Azienda Ospedaliero Universitaria Pisana (Pisa University Hospital). Participants: Patients residing in the territory of the province of Pisa (Tuscany Region) with at least one unplanned hospital admission leading to a medical Diagnosis-Related Group (DRG) in the calendar year 2012...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453825/leveraging-the-full-value-and-impact-of-accreditation
#9
Wendy Nicklin, Triona Fortune, Paul van Ostenberg, Elaine O'Connor, Nicola McCauley
Providing high quality and safe patient care is a challenge in the current rapidly changing and complex health care environment. A variety of independent tools and methodologies contribute to this effort, e.g. regulatory requirements, quality improvement tools and accreditation methodologies. A concern is that each alone will not achieve the tipping point in health care quality that is required. This paper suggests that the methodology and application of accreditation have the potential to be the force to bring these approaches into alignment and ultimately measurably improve the quality of care...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453823/a-flowchart-for-building-evidence-based-care-bundles-in-intensive-care-based-on-a-systematic-review
#10
Marjon Borgert, Jan Binnekade, Frederique Paulus, Astrid Goossens, Dave Dongelmans
Purpose: The Institute for Healthcare Improvement is the founder of the care bundled approach and described the methods used on how to develop care bundles. However, other useful methods are published as well. In this systematic review, we identified what different methods were used to design care bundles in intensive care units. The results were used to build a comprehensive flowchart to guide through the care bundle design process. Data sources: Electronic databases were searched for eligible studies in PubMed, EMBASE and CINAHL from January 2001 to August 2014...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453822/evaluation-of-a-novel-mentor-program-to-improve-surgical-care-for-us-hospitals
#11
Julia R Berian, Juliana M Thomas, Christina A Minami, Paula R Farrell, Kevin J O'Leary, Mark V Williams, Vivek N Prachand, Amy L Halverson, Karl Y Bilimoria, Julie K Johnson
Objective: To evaluate a novel mentor program for 27 US surgeons, charged with improving quality at their respective hospitals, having been paired 1:1 with 27 surgeon mentors through a state-wide quality improvement (QI) initiative. Design: Mixed-methods utilizing quantitative surveys and in-depth semi-structured interviews. Setting: The Illinois Surgical Quality Improvement Collaborative (ISQIC) utilized a novel Mentor Program to guide surgeons new to QI...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453821/quality-of-antenatal-care-and-client-satisfaction-in-kenya-and-namibia
#12
Mai Do, Wenjuan Wang, John Hembling, Paul Ametepi
Objective: Despite much progress in maternal health service coverage, the quality of care has not seen parallel improvement. This study assessed the quality of antenatal care (ANC), an entry point to the health system for many women. Design: The study used data from recent Service Provision Assessment (SPA) surveys of nationally representative health facilities in Kenya and Namibia. Setting: Kenya and Namibia represent the situation in much of sub-Saharan Africa, where ANC is relatively common but maternal mortality remains high...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453721/apheresis-as-novel-treatment-for-refractory-angina-with-raised-lipoprotein-a-a-randomized-controlled-cross-over-trial
#13
Tina Z Khan, Li-Yueh Hsu, Andrew E Arai, Samantha Rhodes, Alison Pottle, Ricardo Wage, Winston Banya, Peter D Gatehouse, Shivraman Giri, Peter Collins, Dudley J Pennell, Mahmoud Barbir
Aims: To determine the clinical impact of lipoprotein apheresis in patients with refractory angina and raised lipoprotein(a) > 500 mg/L on the primary end point of quantitative myocardial perfusion, as well as secondary end points including atheroma burden, exercise capacity, symptoms, and quality of life. Methods: We conducted a single-blinded randomized controlled trial in 20 patients with refractory angina and raised lipoprotein(a) > 500 mg/L, with 3 months of blinded weekly lipoprotein apheresis or sham, followed by crossover...
April 26, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28453714/evaluating-the-effect-of-integrated-microfinance-and-health-interventions-an-updated-review-of-the-evidence
#14
Lara M J Lorenzetti, Sheila Leatherman, Valerie L Flax
Background: Solutions delivered within firm sectoral boundaries are inadequate in achieving income security and better health for poor populations. Integrated microfinance and health interventions leverage networks of women to promote financial inclusion, build livelihoods, and safeguard against high cost illnesses. Our understanding of the effect of integrated interventions has been limited by variability in intervention, outcome, design, and methodological rigour. This systematic review synthesises the literature through 2015 to understand the effect of integrated microfinance and health programs...
June 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28453605/outlier-practice-patterns-in-mohs-micrographic-surgery-defining-the-problem-and-a-proposed-solution
#15
Aravind Krishnan, Tim Xu, Susan Hutfless, Angela Park, Thomas Stasko, Allison T Vidimos, Barry Leshin, Brett M Coldiron, Richard G Bennett, Victor J Marks, Rebecca Brandt, Martin A Makary, John G Albertini
Importance: Outlier physician practices in health care can represent a significant burden to patients and the health system. Objective: To study outlier physician practices in Mohs micrographic surgery (MMS) and the associated factors. Design, Setting, and Participants: This retrospective analysis of publicly available Medicare Part B claims data from January 2012 to December 2014 includes all physicians who received Medicare payments for MMS from any practice performing MMS on the head and neck, genitalia, hands, and feet region of Medicare Part B patients...
April 28, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28453545/the-impact-of-gender-difference-on-clinical-and-echocardiographic-outcomes-in-patients-with-heart-failure-after-cardiac-resynchronization-therapy-a-systematic-review-and-meta-analysis
#16
Fa-Hui Yin, Chun-Lei Fan, Ya-Ya Guo, Hai Zhu, Zhi-Lu Wang
BACKGROUND: Cardiac resynchronization therapy(CRT) has been recommended as a standard treatment for patients with advanced heart failure. However, some studies have reported different clinical and echocardiographic outcomes between male and female patients who received CRT. This Meta-analysis is to determine whether gender difference has any significant impact on clinical and echocardiographic outcomes in patients with heart failure after CRT. METHODS AND RESULTS: PubMed, Embase, and the Cochrane library database were searched...
2017: PloS One
https://www.readbyqxmd.com/read/28453534/vitamin-and-mineral-status-in-chronic-fatigue-syndrome-and-fibromyalgia-syndrome-a-systematic-review-and-meta-analysis
#17
Monica L Joustra, Isidor Minovic, Karin A M Janssens, Stephan J L Bakker, Judith G M Rosmalen
BACKGROUND: Many chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS) patients (35-68%) use nutritional supplements, while it is unclear whether deficiencies in vitamins and minerals contribute to symptoms in these patients. Objectives were (1) to determine vitamin and mineral status in CFS and FMS patients as compared to healthy controls; (2) to investigate the association between vitamin and mineral status and clinical parameters, including symptom severity and quality of life; and (3) to determine the effect of supplementation on clinical parameters...
2017: PloS One
https://www.readbyqxmd.com/read/28453528/guidance-in-author-instructions-of-hematology-and-oncology-journals-a-cross-sectional-and-longitudinal-study
#18
Ingrid Toews, Nadine Binder, Robert F Wolff, Guenes Toprak, Erik von Elm, Joerg J Meerpohl
BACKGROUND: The debate about the value of biomedical publications led to recommendations for improving reporting quality. It is unclear to what extent these recommendations have been endorsed by journals. We analyzed whether specific recommendations were included in author instructions, which journal characteristics were associated with their endorsement, how endorsement of the domains changed and whether endorsement was associated with change of impact factor between 2010 and 2015. METHODS: We considered two study samples consisting of "Hematology" and "Oncology" journals of the Journal Citation Report 2008 and 2014, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28453508/viable-options-for-fertility-preservation-in-breast-cancer-patients-a-focus-on-latin-america
#19
Matteo Lambertini, Oranite Goldrat, Regina Barragan-Carrillo, Giulia Viglietti, Isabelle Demeestere, Cynthia Villarreal-Garza
Thanks to the improved survival outcomes observed in recent years, a growing attention has been given to the quality of life issues faced by young women with breast cancer such as fertility preservation and concerns related to future pregnancies. However, several challenges remain for young women with breast cancer considering undergoing fertility preservation strategies. Further specific issues on this regard should be taken into account in Latin America, where patients and physicians face particular barriers that hinder the routine adoption of this practice...
March 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/28453452/the-efficacy-of-a-huber-exercise-system-mediated-sensorimotor-training-protocol-on-proprioceptive-system-lumbar-movement-control-and-quality-of-life-in-patients-with-chronic-non-specific-low-back-pain
#20
Amir Letafatkar, Maryam Nazarzadeh, Malihe Hadadnezhad, Niloufar Farivar
BACKGROUND: There is a relation between deficits of the proprioceptive system and movement control dysfunction in patients with chronic low back pain (LBP) but, the exact mechanism of this relation is unknown. Exercise therapy has been recognized as an effective method for low back pain treatment. In spite of this, it is not clear which of the various exercise therapy programs lead to better results. OBJECTIVE: Therefore, the present analyze the efficacy of a HUBER study aims to exercise system mediated sensorimotor training protocol on proprioceptive system, lumbar movement control (LMC) and quality of life (QOL) in patients with chronic non-specific LBP...
April 21, 2017: Journal of Back and Musculoskeletal Rehabilitation
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