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https://www.readbyqxmd.com/read/28238025/anesthetic-management-of-abdominal-radical-trachelectomy-for-uterine-cervical-cancer-during-pregnancy
#1
Jun Terukina, Misako Takamatsu, Takayuki Enomoto, Hiroshi Baba
Abdominal radical trachelectomy has been identified as a surgical option for fertility preservation in cervical cancer patients, particularly in pregnant women who strongly desire to continue their pregnancy. Since this procedure requires operating in the uterus, the hardness of the uterus can affect the ease of surgery. Generally, sevoflurane is used for anesthesia in non-obstetric surgery for pregnant women because uterine relaxation is advantageous for uterine blood flow maintenance. However, the use of sevoflurane during radical trachelectomy has not been thoroughly evaluated...
February 25, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28237726/transfer-of-maternal-psychosocial-stress-to-the-fetus
#2
REVIEW
Florian Rakers, Sven Rupprecht, Michelle Dreiling, Christoph Bergmeier, Otto W Witte, Matthias Schwab
Psychosocial maternal stress experienced during different vulnerable periods throughout gestation is thought to increase the individual's risk to develop neuropsychiatric, cardiovascular and metabolic disease in later life. Cortisol has generally been identified as the major mediator of maternal stress transfer to the fetus. Its lipophilic nature allows a trans-placental passage and thus excessive maternal cortisol could persistently impair the development of the fetal hypothalamic-pituitary-adrenal axis (HPAA)...
February 22, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28237345/expression-of-vascular-endothelial-growth-factor-vegf-and-factor-viii-in-the-gilt-placenta-and-its-relation-to-fetal-development
#3
Gregório C Guimarães, Lorena A Alves, Rafael P Betarelli, Camila S O Guimarães, Fernanda R Helmo, Carlos D Pereira Júnior, Rosana R M Corrêa, Márcio G Zangeronimo
Vascular endothelial growth factor (VEGF) and von Willebrand factor (Factor VIII) are important components involved in the regulation of vascular development and identification of endothelial cells in many tissues. This study aimed to evaluate the presence of these substances in the placenta of pig fetuses located in different uterine regions and at different gestational ages and correlate them with fetal development. One hundred seventy-five pig fetuses from fifteen gilts slaughtered at 50, 80 and 106 days of pregnancy were used...
April 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28237326/metabolic-profiling-of-stages-of-healthy-pregnancy-in-hu-sheep-using-nuclear-magnetic-resonance-nmr
#4
Lingwei Sun, Yixuan Guo, Yixuan Fan, Haitao Nie, Ruocheng Wang, Feng Wang
Nutrition is one of the most important factors affecting the reproductive performance of animals. Changes in the ovine maternal metabolism during pregnancy are critical to fetal development. To understand the differences in ovine metabolic changes that occur during normal pregnancy, pregnant ewes carrying twin fetuses (n = 8) were selected at 35 days of gestation (dG). All ewes received 100% of National Research Council (NRC) requirements of all nutrients and energy during this experiment. At 50, 70, 90, and 110 dG, maternal plasma samples were collected and designated as one of four corresponding time points (T1, T2, T3, and T4, respectively)...
April 1, 2017: Theriogenology
https://www.readbyqxmd.com/read/28227866/modelling-nutrient-transfer-based-on-3d-imaging-of-the-human-placental-microstructure
#5
S Perazzolo, R M Lewis, B G Sengers, S Perazzolo, R M Lewis, B G Sengers, B G Sengers, R M Lewis, S Perazzolo
Impaired transfer of nutrients from mother to fetus can affect pregnancy outcomes. The placenta has a complex microstructure, including the maternal intervillous space and fetal capillaries. Previous computational models of placental transfer either assumed a simplified idealized local geometry or were based on 2D imaging. In this study, we present a novel 3D computational model to assess the placental transfer of nutrients at the microscale in interaction with the maternal flow environment. A stack of confocal microscopy images of the placental terminal villi was collected and reconstructed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226646/comparison-of-data-mining-techniques-applied-to-fetal-heart-rate-parameters-for-the-early-identification-of-iugr-fetuses
#6
G Magenes, R Bellazzi, A Malovini, M G Signorini, G Magenes, R Bellazzi, A Malovini, M G Signorini, R Bellazzi, M G Signorini, G Magenes, A Malovini
The onset of fetal pathologies can be screened during pregnancy by means of Fetal Heart Rate (FHR) monitoring and analysis. Noticeable advances in understanding FHR variations were obtained in the last twenty years, thanks to the introduction of quantitative indices extracted from the FHR signal. This study searches for discriminating Normal and Intra Uterine Growth Restricted (IUGR) fetuses by applying data mining techniques to FHR parameters, obtained from recordings in a population of 122 fetuses (61 healthy and 61 IUGRs), through standard CTG non-stress test...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224652/cardio-stic-based-reference-ranges-of-fetal-thymus-size-in-singleton-pregnancies
#7
Sirida Pittyanont, Suchaya Luewan, Theera Tongsong
OBJECTIVES: To establish the reference ranges of the fetal thymus size among Thai fetuses. METHODS: The database of spatio-temporal image correlation (cardio-STIC) was assessed to obtain the volume data sets for offline analysis. The volume data sets acquired at 16 to 38 weeks were measured for the thymus transverse diameter (TD) and the thymus/thoracic (TT) ratio at the three-vessel view. The measured values were regressed to identify the best-fitted model. RESULTS: A total of 622 volumes were successfully measured and the reference ranges of TD and TT ratio were established...
February 22, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28223455/acute-fetal-demise-with-first-trimester-maternal-infection-resulting-from-listeria-monocytogenes-in-a-nonhuman-primate-model
#8
Bryce Wolfe, Gregory J Wiepz, Michele Schotzko, Gennadiy I Bondarenko, Maureen Durning, Heather A Simmons, Andres Mejia, Nancy G Faith, Emmanuel Sampene, Marulasiddappa Suresh, Sophia Kathariou, Charles J Czuprynski, Thaddeus G Golos
Infection with Listeria monocytogenes during pregnancy is associated with miscarriage, preterm birth, and neonatal complications, including sepsis and meningitis. While the risk of these conditions is thought to be greatest during the third trimester of pregnancy, the determinants of fetoplacental susceptibility to infection, the contribution of gestational age, and the in vivo progression of disease at the maternal-fetal interface are poorly understood. We developed a nonhuman primate model of listeriosis to better understand antecedents of adverse pregnancy outcomes in early pregnancy...
February 21, 2017: MBio
https://www.readbyqxmd.com/read/28222448/acute-effects-of-viral-exposure-on-p-glycoprotein-function-in-the-mouse-fetal-blood-brain-barrier
#9
Enrrico Bloise, Sophie Petropoulos, Majid Iqbal, Alisa Kostaki, Tania Maria Ortiga-Carvalho, William Gibb, Stephen G Matthews
BACKGROUND/AIMS: Viral infection during pregnancy is known to affect the fetal brain. The toll-like receptor (TLR)-3 is a pattern recognition receptor activated by viruses known to elicit adverse fetal neurological outcomes. The P-glycoprotein (P-gp) efflux transporter protects the developing fetus by limiting the transfer of substrates across both the placenta and the fetal blood-brain barrier (BBB). As such, inhibition of P-gp at these blood-barrier sites may result in increased exposure of the developing fetus to environmental toxins and xenobiotics present in the maternal circulation...
22, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28222037/cancer-during-pregnancy-clinical-characteristics-treatment-outcomes-and-prognosis-for-mothers-and-infants
#10
Katarina Jeremic, Aleksandar Stefanovic, Jelena Dotlic, Sasa Kadija, Olivera Kontic, Miroslava Gojnic, Jelena Jeremic, Vesna Kesic
OBJECTIVE: To assess which obstetrical characteristics and treatment improved outcomes and prognosis of pregnant women with malignancy. METHODS: A prospective study, undertaken between 2005 and 2014, involving 35 pregnant women who were diagnosed with malignant tumors during pregnancy. Patients were followed-up for 1 year after delivery. The pregnancy course and outcome and parameters that could influence the condition of mother and fetus were evaluated. RESULTS: Most malignancies were hematological, diagnosed in the second trimester and treated with combined therapy (surgery/adjuvant) after pregnancy...
February 21, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28219626/maternal-depression-and-anxiety-and-fetal-neonatal-growth
#11
Tiago Miguel Pinto, Filipa Caldas, Cristina Nogueira-Silva, Bárbara Figueiredo
OBJECTIVE: Maternal depression and anxiety have been found to negatively affect fetal and neonatal growth. However, the independent effects of maternal depression and anxiety on fetal/neonatal growth outcomes and trajectories remain unclear. This study aimed to analyze simultaneously the effects of maternal prenatal depression and anxiety on (1) neonatal growth outcomes, and (2), on fetal/neonatal growth trajectories, from the 2nd trimester of pregnancy to childbirth. METHODS: A sample of 172 women was recruited and completed self-reported measures of depression and anxiety during the 2nd and 3rd trimesters of pregnancy, and at childbirth...
February 17, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28219116/prevalence-timing-of-diagnosis-and-pregnancy-outcome-of-abdominal-wall-defects-after-the-introduction-of-a-national-prenatal-screening-program
#12
Hanneke Fleurke-Rozema, Karline van de Kamp, Marian Bakker, Eva Pajkrt, Caterina Bilardo, Rosalinde Snijders
OBJECTIVE: To examine prevalence, time of diagnosis and outcome of fetuses with an exomphalos or gastroschisis, diagnosed since the introduction of a national prenatal screening program in 2007. METHODS: A prospective cohort study was undertaken in two fetal medicine units in the Netherlands. Cases were included if the estimated due date was between 2009 and 2013. Outcome measures were gestational age at diagnosis, presence of additional anomalies, and pregnancy outcome...
February 20, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28218564/-a-brief-of-gestational-diabetes-mellitus-risk-factors-and-current-criteria-of-diagnosis
#13
Zahra Al-Aissa, Orsolya Hadarits, Klára Rosta, András Zóka, János Rigó, Gábor Firneisz, Anikó Somogyi
Diabetes is one of the most common metabolic disorders that may cause pathological pregnancy. Treating diabetes recognized during pregnancy results in lowering maternal and fetal complications. These patients present higher risk for excessive weight gain, preeclampsia, delivery with cesarean sections, high risk of developing type 2 diabetes and cardiovascular disease in the future. Fetuses of mothers with gestational diabetes are at higher risk for macrosomia and birth trauma, after delivery they present higher risk of developing neonatal hypoglycemia, hyperbilirubinemia, and respiratory distress syndrome...
February 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28217610/disseminated-tuberculosis-in-a-newborn-infant
#14
Tanu Sagar, Kavita Gupta, Mayuri Rani, Iqbal Rajinder Kaur
Tuberculosis (TB) remaining as one of the deadliest communicable diseases. Congenital infection by vertical transmission is rare but high neonatal mortality (up to 60%) and morbidity warrant early and accurate diagnosis of newborns suffering from TB. Intrauterine infection of tuberculosis is most commonly caused by haematogenous spread from the mother causing placental seedling. The organisms reach the fetus via the umbilical vein and the primary focus is often in the fetal liver in hematgenous spread. Another route of infection is by direct ingestion or aspiration of infected amniotic fluid if the placental caseous lesion ruptures directly into the amniotic cavity...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28217238/fetus-in-fetu-case-report-and-brief-review-of-literature-on-embryologic-origin-clinical-presentation-imaging-and-differential-diagnosis
#15
Suhas Aithal Sitharama, Bibekanand Jindal, Mrudula Kumari Vuriti, Bikash Kumar Naredi, Sriram Krishnamurthy, Deepak Barathi Subramania
BACKGROUND: Fetus in fetu (FIF) is a rare entity in which a malformed diamniotic monochorionic parasitic fetal twin develops inside a normal co-twin's body, most commonly in the abdominal cavity. FIF is differentiated from the teratoma by the presence of vertebral column often with an appropriate arrangement of other organs or limbs around it. CASE REPORT: A two-and-a-half-year-old girl presented with a painless abdominal swelling in the right hypochondrium. On imaging, a heterogenous soft tissue mass with internal calcific densities was noted in the retroperitoneum...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28216258/review-systematic-review-of-the-utility-of-the-fetal-cerebroplacental-ratio-measured-at-term-for-the-prediction-of-adverse-perinatal-outcome
#16
REVIEW
Liam Dunn, Helen Sherrell, Sailesh Kumar
AIM: This systematic review evaluates the utility of the fetal cerebroplacental ratio (CPR) when assessed at term (from 37 + 0 weeks gestation) as a predictor of adverse obstetric and perinatal outcomes. DATA SOURCES AND SEARCH STRATEGY: An electronic search of Pubmed and Embase using variations of 'cerebroplacental ratio' and 'cerebroumbilical ratio' was conducted by two independent reviewers. Full text studies written in English that reported on low CPR and its correlation with relevant obstetric and perinatal outcomes were included...
February 12, 2017: Placenta
https://www.readbyqxmd.com/read/28211317/primary-human-cytomegalovirus-hcmv-infection-in-pregnancy
#17
Horst Buxmann, Klaus Hamprecht, Matthias Meyer-Wittkopf, Klaus Friese
BACKGROUND: In 0.5-4% of pregnancies, the prospective mother sustains a primary infection with human cytomegalovirus (HCMV). An HCMV infection of the fetus in the first or second trimester can cause complex post-encephalitic impairment of the infant brain, leading to motor and mental retardation, cerebral palsy, epilepsy, retinal defects, and progressive hearing loss. METHODS: This review is based on pertinent publications from January 2000 to October 2016 that were retrieved by a selective search in PubMed employing the terms "cytomegalovirus and pregnancy" and "congenital cytomegalovirus...
January 27, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28208944/the-effect-of-fetal-gender-on-the-delivery-outcome-in-primigravidae-women-with-induced-labours-for-all-indications
#18
Angeliki Antonakou, Dimitrios Papoutsis
INTRODUCTION: There is increasing evidence of a gender-related phenomenon where the presence of a male fetus may have an adverse effect on the outcome of pregnancy. AIM: The aim of this study was to investigate the effect of fetal gender on the delivery outcome in primigravidae women with induced labours. MATERIALS AND METHODS: This was an observational cohort study of primigravidae women who had Induction Of Labour (IOL) for all indications during a two-year period...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208940/neurological-disorders-complicating-pregnancy-focus-on-obstetric-outcome
#19
Sandya Renukesh, Lavanya Rai
INTRODUCTION: Neurological disorders in pregnancy can be pregnancy related or can be caused by exacerbation of a pre-existing neurological condition or sometimes may even be detected for the first time during pregnancy in which it might be an incidental finding. The diagnosis and management of the neurological disorders in pregnancy is always a challenging task due to varied symptomatology and risks to the fetus. The evaluation and management should be performed in a stepwise fashion and requires multidisciplinary approach...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28208880/balanced-autosomal-translocations-in-two-women-reporting-recurrent-miscarriage
#20
Brindha Arumugam, Chandra R Samuel, Santhiya Sathiyavedu Thyagarajan
Spontaneous abortion or loss of fetus prior to 20 weeks of gestation is observed in 15-20% of clinically recognized pregnancies. Recurrent Miscarriage (RM) is defined as three or more consecutive pregnancy losses and it affects 1-2% of women. Parental chromosomal rearrangements account for 2-5% of RM. This report describes two couples with a clinical history of RM who were subjected to conventional cytogenetic analysis to ascertain the chromosomal aetiology. Analysis of GTG-banded metaphases obtained from cultured lymphocytes at approximately 500-band resolution revealed balanced translocation in the female spouses as 46,XX,t(8;11)(p11...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
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