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Do Young Kim, Ki Tae Yoon, Won Kim, Jung Il Lee, Sung Hwi Hong, Danbi Lee, Jeong Won Jang, Jong Won Choi, Ilsu Kim, Yong Han Paik
BACKGROUND: This study aimed to estimate the direct medical costs of managing chronic hepatitis C (CHC) and its complications based on health-care resources in South Korea. METHODS: The study design was multicenter, retrospective, non-interventional, and observational. Between September 2013 and April 2014, health-care resource data from patients chronically infected with hepatitis C virus, regardless of genotype, were collected from 8 institutions, including data related to outpatient management, emergency care, and hospitalization...
July 2016: Medicine (Baltimore)
Philipp Mandel, Felix Preisser, Markus Graefen, Thomas Steuber, Georg Salomon, Alexander Haese, Uwe Michl, Hartwig Huland, Derya Tilki
: Urinary incontinence (UI) and erectile dysfunction (ED) after radical prostatectomy (RP) can impose a strong burden. While most studies focus on certain time points after RP when analyzing functional outcome, there is paucity of evidence on late functional recovery in patients with UI or ED at 12 mo after RP. Using longitudinal patient data from a large European single-center, we show that the chance of regaining continence among patients (n=974) with UI (≥1 pad/24h) at 12 mo after RP was 38...
October 12, 2016: European Urology
Yu-Liang Zhan, Bin Zou, Ting Kang, Ling-Bing Xiong, Jin Zou, Yun-Feng Wei
BACKGROUND: Accumulating evidence suggests that increased red cell distribution width (RDW) and mean corpuscular volume (MCV) were both poor prognostic factors for patients with cardiovascular diseases. Recently, the multiplicative interaction between RDW and MCV has been observed for predicting mortality in elderly patients without anemia; however, the relationship between the product of RDW-MCV and hypertension-induced target organ damage (TOD) has not been evaluated. METHODS: We performed a cross-sectional study in 1115 hypertensive patients...
October 13, 2016: Journal of Clinical Laboratory Analysis
Long Qin, Guang-Juan Xu, Chan Yao, Yan-Hong Xu
A series of phenylene-based conjugated microporous polymers (CMPs) of the A6 + Mx (x = 2, 3, 4, 6) type were synthesized. By tuning the monomer length and geometry, the BET surface area of CMPs can be tuned from 571 to 1115 m(2) g(-1). Amongst the synthesized CMPs, A6CMP-1 exhibits the highest CO2 adsorption capacity of 1218 mg g(-1) at 318 K and 60 bar pressure. In addition, A6CMP-4 shows a high selectivity ratio of 47 for CO2/N2.
October 18, 2016: Chemical Communications: Chem Comm
Pablo Perez-Martinez, Juan F Alcala-Diaz, Edmon K Kabagambe, Antonio Garcia-Rios, Michael Y Tsai, Javier Delgado-Lista, Genovefa Kolovou, Robert J Straka, Francisco Gomez-Delgado, Paul N Hopkins, Carmen Marin, Ingrid Borecki, Elena M Yubero-Serrano, James E Hixson, Antonio Camargo, Michael A Province, Javier Lopez-Moreno, Fernando Rodriguez-Cantalejo, Francisco J Tinahones, Dimitri P Mikhailidis, Francisco Perez-Jimenez, Donna K Arnett, Jose M Ordovas, Jose Lopez-Miranda
BACKGROUND: Previous studies have suggested that for clinical purposes, subjects with fasting triglycerides (TGs) between 89-180 mg/dl (1-2 mmol/l) would benefit from postprandial TGs testing. OBJECTIVE: To determine the postprandial TG response in 2 independent studies and validate who should benefit diagnostically from an oral-fat tolerance test (OFTT) in clinical practice. METHODS: A population of 1002 patients with coronary heart disease (CHD) from the CORDIOPREV clinical trial and 1115 white US subjects from the GOLDN study underwent OFTTs...
September 2016: Journal of Clinical Lipidology
Monica Attanasio, Rossella Marcucci, Anna Maria Gori, Rita Paniccia, Serafina Valente, Daniela Balzi, Alessandro Barchielli, Nazario Carrabba, Renato Valenti, David Antoniucci, Rosanna Abbate, Gian Franco Gensini
INTRODUCTION: Thrombin generation (TG) is a central step of the coagulation system involved in hemostatic and thrombotic roles. Scarce data evaluating in the acute phase the association between TG and the risk of cardiovascular death of acute coronary syndrome (ACS) patients are available, in the era of percutaneous coronary intervention (PCI) and stenting with the use of dual antiplatelet treatment. MATERIALS AND METHODS: We investigated TG in 292 ACS patients undergoing PCI with stent implantation on dual antiplatelet treatment...
September 19, 2016: Thrombosis Research
Hongbiao Yin, Shenghua Huang, Wenlan Wang
Based on an adjusted Job Demands-Resources (JD-R) model that considers the mediation of personal resources, this study examined the relationships between two characteristics of teachers' work environment (i.e., emotional job demands and trust in colleagues) and two indicators of teachers' well-being (i.e., teaching satisfaction and emotional exhaustion). In particular, the study focused on how emotion regulation strategies (i.e., reappraisal and suppression) mediate these relationships. Data collected from a questionnaire survey of 1115 primary school teachers in Hong Kong was analyzed to test the hypothesized relationships...
2016: International Journal of Environmental Research and Public Health
Lee Revere, Adele Semaan, Nicole Lievsay, Jessica Hall, Zheng M Wang, Charles Begley
The Texas Medicaid 1115 Transformation Waiver reforms the state's safety net systems by creating a Delivery System Reform Incentive Payment incentive pool for innovative healthcare delivery. The Waiver supports the design and implementation of transformative projects. As part of the Waiver requirements, regions created Learning Collaboratives to collaborate on project implementation and outcomes. This paper describes the experience of one region in adapting the Institute for Healthcare Improvement Breakthrough Series (IHI BTS) model, as a framework for their Learning Collaborative...
September 13, 2016: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
Penglian Wang, Yilong Wang, Xingquan Zhao, Wanliang Du, Anxin Wang, Gaifen Liu, Liping Liu, Ruijun Ji, Chunxue Wang, Kehui Dong, Yongjun Wang
In-hospital medical complications are common and strongly associated with the risk of death and dependency in stroke patients. Whether similar associations extend to stroke recurrence is unclear. We prospectively and systematically investigated whether in-hospital medical complications are associated with recurrent stroke of patients in the China National Stroke Registry (CNSR). We examined patients with initial ischemic stroke enrolled in CNSR between 2007 and 2008. Recurrent stroke at 3, 6, and 12 months post-stroke was used as stroke outcome...
September 2016: Medicine (Baltimore)
Chunjie Li, Jie Lin, Yi Men, Wenbin Yang, Fanglin Mi, Longjiang Li
PURPOSE: Whether mandibular involvement by oral squamous cell carcinoma (OSCC) could be identified as a factor for cancer staging and prognosis prediction remains a subject of debate. In addition, the influence of different types of mandibular invasion (cortical or medullary invasion) on patients' prognosis remains unclear. The aim of this systematic review was to establish whether mandibular invasion or its subset should be considered an independent prognostic factor for patients with OSCC...
August 18, 2016: Journal of Oral and Maxillofacial Surgery
Mohammad Reza Aghasadeghi, Ali Akbar Velayati, Setareh Mamishi, Mahmood Nabavi, Arezoo Aghakhani, Farahnaz Bidari-Zerehpoosh, Mohammad-Taghi Haghi Ashtiani, Shahram Sabeti, Mohammad Banifazl, Fatemeh Azimian-Zavareh, Fatemeh Motevalli, Sepehr Soleymani, Amitis Ramezani
A nationwide hepatitis B virus (HBV) vaccination program for neonates was launched in Iran in 1993. Despite the success of this program, concern about its long-term success still remains, because breakthrough infections due to emergence of surface mutants have been reported in immunized children. We aimed to evaluate the seroprevalence of HBV and vaccine escape mutants among individuals born after the initiation of the nationwide vaccination program in Iran. This study included 1115 participants younger than 23 years old, with 223 in each age cohort...
December 2016: Archives of Virology
Sara E Espinoza, Chen-Pin Wang, Devjit Tripathy, Stephen C Clement, Dawn C Schwenke, Mary Ann Banerji, George A Bray, Thomas A Buchanan, Robert R Henry, Abbas E Kitabchi, Sunder Mudaliar, Frankie B Stentz, Peter D Reaven, Ralph A DeFronzo, Nicolas Musi
To determine the efficacy of pioglitazone to prevent type 2 diabetes in older compared to younger adults with pre-diabetes. Six hundred two participants with impaired glucose tolerance (IGT) were randomized in double blind fashion to placebo or pioglitazone for diabetes prevention in the ACT NOW study (NEJM 364:1104-1115, 2011). Cox proportional hazard regression was used to compare time to development of diabetes over a mean of 2 years between older (≥61 years) and younger participants. We compared effects of pioglitazone versus placebo on metabolic profiles, inflammatory markers, adipokines, β cell function (disposition index), insulin sensitivity (Matsuda index), and body composition by ANOVA...
September 1, 2016: Age (2005-)
Shane A Bielko, Allison J Campbell, Chad C Wiggins, Timothy D Mickleborough, Robert F Chapman
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Alynne da Silva Barbosa, Otilio Machado Pereira Bastos, Claudia Maria Antunes Uchôa, Alcides Pissinatti, Augusto César Machado Pereira Bastos, Igo Vieira de Souza, Laís Verdan Dib, Eduarda Peixoto Azevedo, Mayara Perlingeiro de Siqueira, Matheus Lessa Cardozo, Maria Regina Reis Amendoeira
Balantidium coli is a protozoon that can cause dysentery in humans, pigs and nonhuman primates, with zoonotic potential. In the literature, there is still little information on the effectiveness of different laboratory techniques for diagnosing this disease. This study compared and evaluated the performance of the Lutz, modified Ritchie, Faust, modified Sheather and direct examination techniques for detecting cysts of this protozoon. Between 2012 and 2014, 1905 fecal samples were collected from captive animals in the state of Rio de Janeiro...
July 2016: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
Saadullah Khan, Imran Ullah, Abdul Nasir, C Arnoud Meijer, Marlies Laurense-Bik, Johan T den Dunnen, Claudia A L Ruivenkamp, Mariëtte J V Hoffer, Gijs W E Santen, Wasim Ahmad
Postaxial polydactyly (PAP) is one of the most common congenital malformations observed in the general population. However, it can also occur as part of a syndrome. Unbiased genetic screening techniques such as exome sequencing are highly appropriate methods to provide a molecular diagnosis in patients with polydactyly due to the large number of mutated genes associated with it. The present study describes a consanguineous family of Pakistani origin with PAP, speech impairment, hearing impairment of variable degree, and proportionate short stature with no prominent intellectual disability or ophthalmological abnormalities...
August 29, 2016: American Journal of Medical Genetics. Part A
Vidyut Bhatia, Shivani Deswal, Swati Seth, Akshay Kapoor, Anupam Sibal, Sarath Gopalan
BACKGROUND: Functional gastrointestinal diseases (FGIDs) are emerging as an important cause of morbidity in adolescents globally. The prevalence of FGIDs among Indian children or adolescents is not clear. METHODS: A cross-sectional school-based survey conducted in 1115 children aged 10-17 years attending four semi urban government schools of National capital territory (NCT) of Delhi. Rome III questionnaire was translated into Hindi and was filled by the students under supervision...
July 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Ranjita Das, Frank Neese, Maurice van Gastel
In this work, a detailed quantum chemical study of the mechanism of [Ni(bdt)(dppf)] (Ni(II)L) catalyzed hydrogen formation [A. Gan, T. L. Groy, P. Tarakeshwar, S. K. S. Mazinani, J. Shearer, V. Mujica and A. K. Jones, J. Am. Chem. Soc., 2015, 137, 1109-1115] following an electro-chemical-electro-chemical (ECEC) pathway is reported. The complex exclusively catalyzes the reduction of protons to molecular hydrogen. The calculations suggest that the first one-electron reduction of the [Ni(II)L] catalyst is the rate limiting step of the catalytic cycle and hence, the buildup of detectable reaction intermediates is not expected...
September 21, 2016: Physical Chemistry Chemical Physics: PCCP
Christina Sandlund, Jeanette Westman, Jerker Hetta
OBJECTIVE: This study aims to investigate factors associated with the self-reported need for treatment of sleeping difficulties in the general population. METHODS: This study consisted of a cross-sectional telephone survey of 1550 people randomly selected from the total population of Sweden. The survey, conducted by the Swedish national statistics agency, Statistics Sweden, was completed by 1115 people aged 18-85 years. Participants were asked about sleep patterns, daytime symptoms, physical and mental health disorders, use of prescribed hypnotics, help-seeking behaviors, and sociodemographic characteristics...
June 2016: Sleep Medicine
Fang-Fang Ma, Xiao-Yi Wu, Yun-Xia Chen, Ying-Na Liu, Zhu-Qing Shao, Ping Wu, Mian Wu, Cheng-Chen Liu, Wen-Ping Wu, Jia-Yin Yang, De-Xiao Li, Jian-Qun Chen, Bin Wang
The Rsv1 - h gene in cultivar Suweon 97, which confers resistance to SMVs, was mapped to a 97.5-kb location (29,815,195-29,912,667 bp on chromosome 13) in the Rsv1 locus, thereby providing additional insights into the molecular nature underlying variations in resistance alleles in this particular locus. Soybean mosaic virus (SMV) is a well-known devastating pathogen of soybean (Glycine max (L.) Merrill.) causing significant yield losses and seed quality deterioration. A single dominant allele, Rsv1-h, which confers resistance to multiple SMV strains, was previously reported in the cultivar Suweon 97, but its exact location is unknown...
August 20, 2016: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
Kishore K Deepak, Khalid Umran Al-Umran, Mona H AI-Sheikh, B V Dkoli, Abdullah Al-Rubaish
OBJECTIVES: The functionality of distracters in a multiple choice question plays a very important role. We examined the frequency and impact of functioning and non-functioning distracters on psychometric properties of 5-option items in clinical disciplines. METHODS: We analyzed item statistics of 1115 multiple choice questions from 15 summative assessments of undergraduate medical students and classified the items into five groups by their number of non-functioning distracters...
October 2015: Indian Journal of Physiology and Pharmacology
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